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List of works by Lício Velloso

(-)-Tarchonanthuslactone exerts a blood glucose-increasing effect in experimental type 2 diabetes mellitus

scientific article published on 19 March 2015

A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamycin (mTOR) in high-protein diet-induced weight loss.

scientific article published on 05 December 2007

A central role for neuronal adenosine 5'-monophosphate-activated protein kinase in cancer-induced anorexia

scientific article published on 23 August 2007

A20 deubiquitinase controls PGC-1α expression in the adipose tissue.

scientific article

Ablation of primary afferent neurons by neonatal capsaicin treatment reduces the susceptibility of the portal hypertensive gastric mucosa to ethanol-induced injury in cirrhotic rats

scientific journal article

Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency

scientific article published on 27 November 2018

Abstract: Analysis of Proinflammatory Markers in Lipofilled Breast Microenvironment in a Murine Model.

scientific article published in September 2017

Activation of AMPK in rat hypothalamus participates in cold-induced resistance to nutrient-dependent anorexigenic signals.

scientific article

Activation of GPR40 induces hypothalamic neurogenesis through p38- and BDNF-dependent mechanisms

scientific article published on 06 July 2020

Acute exercise modulates the Foxo1/PGC-1alpha pathway in the liver of diet-induced obesity rats

scientific journal article

Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice

scientific article published on 26 April 2010

Acute exercise reduces insulin resistance-induced TRB3 expression and amelioration of the hepatic production of glucose in the liver of diabetic mice.

scientific article

Acute exercise reverses aged-induced impairments in insulin signaling in rodent skeletal muscle

scientific article published on 20 March 2010

Acute physical exercise reverses S-nitrosation of the insulin receptor, insulin receptor substrate 1 and protein kinase B/Akt in diet-induced obese Wistar rats.

scientific article published in November 2007

AdipoR1 mediates the anorexigenic and insulin/leptin-like actions of adiponectin in the hypothalamus

scientific journal article

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation.

scientific article

Amelioration of diet-induced diabetes mellitus by removal of visceral fat.

scientific article

Angiotensin II (AngII) induces the expression of suppressor of cytokine signaling (SOCS)-3 in rat hypothalamus - a mechanism for desensitization of AngII signaling.

scientific article published in April 2004

Anthracycline Therapy Is Associated With Cardiomyocyte Atrophy and Preclinical Manifestations of Heart Disease

Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts.

scientific article published on 9 February 2008

Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats

scientific article (publication date: 30 July 2004)

Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals

scientific article (publication date: 6 June 2005)

Assessing Specimens of Devitalized Tissue in Chronic Sacral Pressure Ulcers: A Pilot Study.

scientific article published in December 2017

Assessment of the Cancer Risk of the Fat-Grafted Breast in a Murine Model

scientific article published on 7 December 2016

Asthma and COVID-19: a systematic review

scientific article published on 06 January 2021

Atypical transforming growth factor-β signaling in the hypothalamus is linked to diabetes

scientific article published on 01 September 2014

Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway.

scientific article published on 14 November 2009

Autophagy is decreased in mesenteric fat tissue but not in intestinal mucosae of patients with Crohn's disease

scientific article published on 05 September 2012

Birth weight and type 2 diabetes in adults.

scientific article published in April 2009

Blockade of IRS1 in isolated rat pancreatic islets improves glucose-induced insulin secretion

scientific journal article

Breast Lipofilling Does Not Pose Evidence of Chronic Inflammation in Rats

scientific article published on 01 May 2019

CD1 is involved in diet-induced hypothalamic inflammation in obesity

scientific article published on 17 January 2019

Central leptin action improves skeletal muscle AKT, AMPK, and PGC1 alpha activation by hypothalamic PI3K-dependent mechanism

scientific article published on 19 August 2009

Central role of obesity in endothelial cell dysfunction and cardiovascular risk

scientific article published on 01 January 2019

Chaperone Insufficiency Links TLR4 Protein Signaling to Endoplasmic Reticulum Stress ⬇️

scientific article published on March 16, 2012

Chaperone insufficiency links TLR4 signaling to endoplasmic reticulum stress

scientific article published on December 2016

Chronic exercise reduces hypothalamic transforming growth factor-β1 in middle-aged obese mice

scientific article published on 28 August 2017

Ciliary neurotrophic factor infused intracerebroventricularly shows reduced catabolic effects when linked to the TAT protein transduction domain

scientific article

Citrate diminishes hypothalamic acetyl-CoA carboxylase phosphorylation and modulates satiety signals and hepatic mechanisms involved in glucose homeostasis in rats

scientific article published on 6 May 2008

Cold exposure induces tissue-specific modulation of the insulin-signalling pathway in Rattus norvegicus

scientific article published in August 2003

Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway.

scientific article

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.

scientific article published on 7 July 2005

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice.

scientific article published on November 2016

Cross-talk between the insulin and leptin signaling systems in rat hypothalamus.

scientific article

Defective insulin and acetylcholine induction of endothelial cell-nitric oxide synthase through insulin receptor substrate/Akt signaling pathway in aorta of obese rats

scientific article published on 17 January 2007

Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity

scientific article published on 04 July 2016

Defective regulation of the ubiquitin/proteasome system in the hypothalamus of obese male mice.

scientific article

Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis

scientific article published on 26 October 2009

Deletion of tumor necrosis factor-α receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis.

scientific article published on December 2016

Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas).

scientific article published on 7 June 2015

Detection of epithelial apoptosis in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis

scientific article

Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control

scientific article

Diet-induced inflammation of the hypothalamus in obesity.

scientific article published on 09 September 2008

Dietary fats promote functional and structural changes in the median eminence blood/spinal fluid interface-the protective role for BDNF.

scientific article published on 9 January 2018

Differential expression of TLR2, TLR4 and JNK in mucosa of ileal pouches for ulcerative colitis. Is there a role for bacterial antigen pathway in asymptomatic patients?

scientific article

Disfunção hipotalâmica na obesidade ⬇️

scientific article published on August 1, 2012

Disruption of metabolic pathways--perspectives for the treatment of cancer.

scientific article

Distinct subsets of hypothalamic genes are modulated by two different thermogenesis-inducing stimuli

scientific article

Downregulation of HIF complex in the hypothalamus exacerbates diet-induced obesity

scholarly article by Joana M. Gaspar et al published October 2018 in Brain, Behavior, and Immunity

Dynamic changes in DICER levels in adipose tissue control metabolic adaptations to exercise

scientific article published on 08 September 2020

Effect of Captopril, Losartan, and Bradykinin on Early Steps of Insulin Action ⬇️

scientific article published on December 1, 1997

Effect of pioglitazone treatment on brown adipose tissue volume and activity and hypothalamic gliosis in patients with type 2 diabetes mellitus: a proof-of-concept study

scientific article published on 10 September 2019

Effect of thiopental, pentobarbital and diethyl ether on early steps of insulin action in liver and muscle of the intact rat.

scientific article published in April 2005

Effects of taurine supplementation upon food intake and central insulin signaling in malnourished mice fed on a high-fat diet.

scientific article

Effects of topical topiramate in wound healing in mice

scientific article published on 23 February 2018

Endoplasmic reticulum stress, obesity and diabetes

scientific article published on 31 August 2011

Endothelin and neonatal capsaicin regulate gastric resistance to injury in BDL rats

scientific article

Endurance training improves responsiveness to insulin and modulates insulin signal transduction through the phosphatidylinositol 3-kinase/Akt-1 pathway

scientific article published in July 2002

Endurance training stimulates growth and survival pathways and the redox balance in rat pancreatic islets ⬇️

scientific article published on December 15, 2011

Erratum to: Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in the Brain-Adipocyte Axis.

scientific article published on 18 May 2017

Exercise activates the hypothalamic S1PR1-STAT3 axis through the central action of interleukin 6 in mice

scientific article published on 31 July 2018

Exercise improves insulin and leptin sensitivity in hypothalamus of Wistar rats

scientific article published in September 2006

Exercise intensity, inflammatory signaling, and insulin resistance in obese rats.

scientific article published in December 2010

Exercise training reduces insulin resistance and upregulates the mTOR/p70S6k pathway in cardiac muscle of diet-induced obesity rats

scientific article published in March 2011

Expression of Concern. A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet-Induced Weight Loss. Diabetes 2008;57:594-605. DOI: 10.2337/db07-0573.

scientific article published in April 2016

Expression of Concern. EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet-Fed Mice. Diabetes 2009;58:2910-2919. DOI: 10.2337/db08-0506. PMID: 19696185.

scientific article published on 10 February 2017

Expression of Concern. Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei. Diabetes 2013;62:137-148. DOI: 10.2337/db11-1388.

scientific article published on April 2016

Extra-pancreatic insulin production in RAt lachrymal gland after streptozotocin-induced islet beta-cells destruction

scientific article published on 21 May 2007

Fractalkine (CX3CL1) is involved in the early activation of hypothalamic inflammation in experimental obesity

scientific article published on 19 June 2014

Freeze-dried jaboticaba peel powder improves insulin sensitivity in high-fat-fed mice.

scientific article published on 18 February 2013

Fructose-induced hypothalamic AMPK activation stimulates hepatic PEPCK and gluconeogenesis due to increased corticosterone levels

scientific article published on 14 May 2012

Fyn mediates leptin actions in the thymus of rodents

scientific article published on 3 November 2009

Genetic analysis of hereditary angioedema in a Brazilian family by targeted next generation sequencing

scientific article published in April 2016

Glucagon-Like Peptide-1 Receptor Agonists (GLP-1RAs) in the Brain-Adipocyte Axis

scientific article published on 23 February 2017

Grape peel powder attenuates the inflammatory and oxidative response of experimental colitis in rats by modulating the NF-κB pathway and activity of antioxidant enzymes

scientific article published on 31 January 2020

Gut-to-brain signals in feeding control

scientific article published on 07 December 2020

High-fat diet induces apoptosis of hypothalamic neurons

scientific article

Hypothalamic IRX3: A New Player in the Development of Obesity

scientific article published on 05 February 2020

Hypothalamic Inhibition of Acetyl-CoA Carboxylase Stimulates Hepatic Counter-Regulatory Response Independent of AMPK Activation in Rats ⬇️

scientific article published on April 23, 2013

Hypothalamic Microglial Activation in Obesity: A Mini-Review

article

Hypothalamic S1P/S1PR1 axis controls energy homeostasis.

scientific article published on 25 September 2014

Hypothalamic action of glutamate leads to body mass reduction through a mechanism partially dependent on JAK2.

scientific article published in April 2012

Hypothalamic actions of tumor necrosis factor alpha provide the thermogenic core for the wastage syndrome in cachexia

scientific article published on 8 December 2009

Hypothalamic dysfunction in obesity.

scientific article published on January 2009

Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation

scholarly article by Arine M. Melo et al published May 2014 in Metabolism

Hypothalamic expression of the atypical chemokine receptor ACKR2 is involved in the systemic regulation of glucose tolerance

scientific article published on 07 February 2019

Hypothalamic inflammation and obesity.

scientific article published on January 2010

Hypothalamic inflammation and thermogenesis: the brown adipose tissue connection ⬇️

scientific article published on February 1, 2011

Hypothalamic melanin-concentrating hormone is induced by cold exposure and participates in the control of energy expenditure in rats

scientific journal article

Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity

scientific article published on 28 July 2017

Hypothalamic neuronal cellular and subcellular abnormalities in experimental obesity

scientific article published on 23 September 2019

Hypoxia Inducible Factor as a Central Regulator of Metabolism - Implications for the Development of Obesity

article

IKKε is key to induction of insulin resistance in the hypothalamus, and its inhibition reverses obesity

scientific article published on 8 May 2014

IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition

scientific article

Identification of insulin in the tear film and insulin receptor and IGF-1 receptor on the human ocular surface.

scientific article

Impact of gender on insulin signaling pathway in lacrimal and salivary glands of rats

scientific article published in July 2002

Impairment of body mass reduction-associated activation of brown/beige adipose tissue in patients with type 2 diabetes mellitus.

scientific article

In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus.

scientific article published in August 2004

Increased airway reactivity and hyperinsulinemia in obese mice are linked by ERK signaling in brain stem cholinergic neurons.

scientific article

Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-alpha on hypothalamic insulin-dependent inhibition of food intake

scientific article published on 21 July 2006

Inflammation of the hypothalamus leads to defective pancreatic islet function

scientific article published on 01 December 2016

Inflammation of the hypothalamus leads to defective pancreatic islet function.

scientific article

Infliximab prevents increased systolic blood pressure and upregulates the AKT/eNOS pathway in the aorta of spontaneously hypertensive rats

scientific article published on 7 December 2012

Infliximab restores glucose homeostasis in an animal model of diet-induced obesity and diabetes

scientific article published on 30 August 2007

Infliximab reverses steatosis and improves insulin signal transduction in liver of rats fed a high-fat diet

scientific journal article

Inhibition of 72 kDa inositol polyphosphate 5-phosphatase E improves insulin signal transduction in diet-induced obesity.

scientific article

Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action

scientific article published on 05 January 2007

Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats.

scientific article

Inhibition of hypothalamic inflammation reverses diet-induced insulin resistance in the liver.

scientific article published on 20 April 2012

Inhibition of hypothalamic leukemia inhibitory factor exacerbates diet-induced obesity phenotype

scientific article published on 2 September 2017

Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet.

scientific article published on 11 September 2008

Initial evidence for hypothalamic gliosis in children with obesity by quantitative T2 MRI and implications for blood oxygen-level dependent response to glucose ingestion

scientific article published on 10 December 2018

Insulin secretion by rat lacrimal glands: effects of systemic and local variables

scientific article published on 28 June 2005

Insulin, insulin receptor and insulin-like growth factor-I receptor on the human ocular surface.

scientific article published in January 2002

Interaction between leptin and insulin signaling pathways differentially affects JAK-STAT and PI 3-kinase-mediated signaling in rat liver.

scientific article published in January 2003

Interleukin-10 is a protective factor against diet-induced insulin resistance in liver

scientific article published on 31 January 2008

Interleukin-17 acts in the hypothalamus reducing food intake

scientific article published on 18 December 2019

Interleukin-6 Expression by Hypothalamic Microglia in Multiple Inflammatory Contexts: A Systematic Review

scientific article published on 22 August 2019

Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating

scientific article

Intracerebroventricular injection of citrate inhibits hypothalamic AMPK and modulates feeding behavior and peripheral insulin signaling

scientific article published on 9 May 2008

Leptin action in the thymus

scientific article published on February 2009

Leptin inhibits apoptosis in thymus through a janus kinase-2-independent, insulin receptor substrate-1/phosphatidylinositol-3 kinase-dependent pathway.

scientific article published on 27 July 2006

Leptin, Neuroinflammation and Obesity

scientific article published on 28 February 2017

Long-term disruption of maternal glucose homeostasis induced by prenatal glucocorticoid treatment correlates with miR-29 upregulation.

scientific article

Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance

scientific article published on 22 May 2007

Low-Grade Hypothalamic Inflammation Leads to Defective Thermogenesis, Insulin Resistance, and Impaired Insulin Secretion ⬇️

scientific article published on January 25, 2011

MECHANISMS IN ENDOCRINOLOGY: Hypothalamic inflammation and nutrition

scientific article

MECHANISMS IN ENDOCRINOLOGY: Metabolic and inflammatory pathways on the pathogenesis of type 2 diabetes

scientific article

Maternal Consumption of High-Fat Diet Disturbs Hypothalamic Neuronal Function in the Offspring: Implications for the Genesis of Obesity ⬇️

scientific article published on February 1, 2012

Maternal high-fat feeding through pregnancy and lactation predisposes mouse offspring to molecular insulin resistance and fatty liver ⬇️

scientific article published on May 2, 2011

Mechanisms Mediating the Actions of Fatty Acids in the Hypothalamus

scientific article published on 02 November 2019

Melanin-concentrating hormone induces insulin resistance through a mechanism independent of body weight gain

scientific journal article

Melatonin acts through MT1/MT2 receptors to activate hypothalamic Akt and suppress hepatic gluconeogenesis in rats.

scientific article

Methods for assessing and modulating UCP2 expression and function.

scientific article

Modulation of growth hormone signal transduction in kidneys of streptozotocin-induced diabetic animals: effect of a growth hormone receptor antagonist.

scientific article published in July 2002

Molecular and functional resistance to insulin in hypothalamus of rats exposed to cold

scientific article published on 18 March 2003

Neuroendocrine body weight regulation: integration between fat tissue, gastrointestinal tract, and the brain.

scientific article published on March 2010

Nitric oxide released from luminal s-nitroso-N-acetylcysteine increases gastric mucosal blood flow.

scientific article published on 4 March 2015

Noninvasive imaging assessment of rehabilitation therapy in heart failure with preserved and reduced left ventricular ejection fraction (IMAGING-REHAB-HF): design and rationale

scientific article published on 22 August 2019

Novel fibrin-fibronectin matrix accelerates mice skin wound healing

scientific article published on 01 July 2020

Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and phosphoinositol 3-kinase/Akt pathways.

scientific article published in February 2003

Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α

scientific article published on 01 February 2020

Paradoxical elevation of systemic inflammatory markers and physical activity in patients with schizophrenia

scientific article published on 30 August 2017

Partial reversibility of hypothalamic dysfunction and changes in brain activity after body mass reduction in obese subjects.

scientific article

Participation of prolactin receptors and phosphatidylinositol 3-kinase and MAP kinase pathways in the increase in pancreatic islet mass and sensitivity to glucose during pregnancy.

scientific article published on December 2004

Patients with Schizophrenia Undergoing Gastric Bypass Surgery: a Case Series Study

scientific article published on 25 May 2020

Phosphoinositide-specific inositol polyphosphate 5-phosphatase IV inhibits inositide trisphosphate accumulation in hypothalamus and regulates food intake and body weight

scientific article published on 17 August 2006

Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

scientific article published on 26 April 2017

Pro-opiomelanocortin (POMC) neuron translatome signatures underlying obesogenic gestational malprogramming in mice

scientific article published on 15 February 2020

Proopiomelanocortin Processing in the Hypothalamus Is Directly Regulated by Saturated Fat: Implications for the Development of Obesity

scientific article published on 20 May 2019

Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes.

scientific article

RETRACTED: EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat diet-fed mice.

scientific article published on 20 August 2009

Radiologic evidence that hypothalamic gliosis is improved after bariatric surgery in obese women with type 2 diabetes

scientific article published on 14 June 2019

Rapid clinical recovery of a SARS-CoV-2 infected common variable immunodeficiency patient following the infusion of COVID-19 convalescent plasma

scientific article published in 2021

Reactive oxygen species production is increased in the peripheral blood monocytes of obese patients

scientific article published on 18 June 2009

Reduction of endoplasmic reticulum stress--a novel mechanism of action of statins in the protection against atherosclerosis

scientific article published on 6 May 2010

Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance

scientific journal article

Resolvin RvD2 reduces hypothalamic inflammation and rescues mice from diet-induced obesity

scientific article published on 05 January 2017

Retracted: Central Exercise Action Increases the AMPK and mTOR Response to Leptin

retracted article

Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade

scientific article published on 26 November 2002

Reversal of diet-induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS-1 serine phosphorylation

scientific article published on 28 September 2006

RhoA/ROCK signaling is critical to FAK activation by cyclic stretch in cardiac myocytes.

scientific article

Role of mitochondria in the immune response to cancer: a central role for Ca2+

scientific article published on 01 February 2006

S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance.

scientific article

SARS-CoV-2 receptor is co-expressed with elements of the kinin-kallikrein, renin-angiotensin and coagulation systems in alveolar cells

scientific article published on 11 November 2020

Saturated fatty acids modulate autophagy's proteins in the hypothalamus

scientific article

Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

scientific journal article

Short dietary intervention with olive oil increases brown adipose tissue activity in lean but not overweight subjects

scientific article published on 12 November 2020

Short-term in vivo inhibition of insulin receptor substrate-1 expression leads to insulin resistance, hyperinsulinemia, and increased adiposity.

scientific article published on 18 November 2004

Solidago chilensis Meyen hydroalcoholic extract reduces JNK/IκB pathway activation and ameliorates insulin resistance in diet-induced obesity mice ⬇️

scientific article published on August 15, 2011

Statement of Retraction. A Central Role for Neuronal AMP-Activated Protein Kinase (AMPK) and Mammalian Target of Rapamycin (mTOR) in High-Protein Diet-Induced Weight Loss. Diabetes 2008;57:594-605. DOI: 10.2337/db07-0573.

scientific article published on 10 February 2017

Statement of Retraction. EGFR Tyrosine Kinase Inhibitor (PD153035) Improves Glucose Tolerance and Insulin Action in High-Fat Diet-Fed Mice. Diabetes 2009;58:2910-2919. DOI: 10.2337/db08-0506. PMID: 19696185.

scientific article

Statement of Retraction. Effect of Captopril, Losartan, and Bradykinin on Early Steps of Insulin Action. Diabetes 1997;46:1950-1957. DOI: 10.2337/diab.46.12.1950

scientific article published on 01 April 2016

Statement of Retraction. Exercise Improves Insulin and Leptin Sensitivity in Hypothalamus of Wistar Rats. Diabetes 2006;55:2554-2561. DOI: 10.2337/db05-1622

scientific article published on 01 April 2016

Statement of Retraction. Loss-of-Function Mutation in Toll-Like Receptor 4 Prevents Diet-Induced Obesity and Insulin Resistance. Diabetes 2007;56:1986-1998. DOI: 10.2337/db06-1595

scientific article published on 01 April 2016

Statement of Retraction. Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei. Diabetes 2013;62:137-148. DOI: 10.2337/db11-1388.

scientific article published on 10 February 2017

Suppressor of cytokine signaling 3 is induced by angiotensin II in heart and isolated cardiomyocytes, and participates in desensitization

scientific article published on 26 June 2003

Suppressor of cytokine signaling-3 Provides a novel interface in the cross-talk between angiotensin II and insulin signaling systems

scientific article

TGF-β1 down-regulation in the mediobasal hypothalamus attenuates hypothalamic inflammation and protects against diet-induced obesity

scientific article published on 13 April 2018

TGF-β1 downregulation in the hypothalamus of obese mice through acute exercise

scientific article published on 29 May 2019

TLR4 at the Crossroads of Nutrients, Gut Microbiota, and Metabolic Inflammation.

scientific article published on 26 March 2015

TLR4 expression in bone marrow-derived cells is both necessary and sufficient to produce the insulin resistance phenotype in diet-induced obesity

scientific article published in January 2015

TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient--effects on leptin and insulin signaling pathways

scientific article

TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.

scientific article published in December 2013

Targeted disruption of iNOS prevents LPS-induced S-nitrosation of IRbeta/IRS-1 and Akt and insulin resistance in muscle of mice.

scientific article published on 25 April 2006

Targeted disruption of inducible nitric oxide synthase protects against aging, S-nitrosation, and insulin resistance in muscle of male mice

scientific article published on 18 September 2012

Taurine enhances the anorexigenic effects of insulin in the hypothalamus of rats.

scientific article published on 5 August 2011

Taurine supplementation modulates glucose homeostasis and islet function

scientific article published on 15 August 2008

The Obese Brain--Effects of Bariatric Surgery on Energy Balance Neurocircuitry

scientific article

The bile acid TUDCA improves glucose metabolism in streptozotocin-induced Alzheimer's disease mice model

scientific article published on 13 December 2020

The cross-talk between angiotensin and insulin differentially affects phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-mediated signaling in rat heart: implications for insulin resistance.

scientific article published on 4 September 2003

The crosstalk between insulin and renin-angiotensin-aldosterone signaling systems and its effect on glucose metabolism and diabetes prevention.

scientific article

The immunosuppressant drug, thalidomide, improves hepatic alterations induced by a high-fat diet in mice.

scientific article

The influence of ageing on the insulin signalling system in rat lacrimal and salivary glands

scientific article

The influence of aging in the insulin-signaling system in rat exocrine glands

scientific article published on 01 January 2002

The multi-faceted cross-talk between the insulin and angiotensin II signaling systems.

scientific article

The partial inhibition of hypothalamic IRX3 exacerbates obesity

scientific article published on 03 December 2018

The pathophysiology of defective proteostasis in the hypothalamus - from obesity to ageing

scientific article

The phosphatidylinositol/AKT/atypical PKC pathway is involved in the improved insulin sensitivity by DHEA in muscle and liver of rats in vivo

scientific article published in November 2004

The role of proliferator-activated receptor gamma coactivator-1alpha in the fatty-acid-dependent transcriptional control of interleukin-10 in hepatic cells of rodents.

scientific article

The thymus is a common target in malnutrition and infection

scientific article published on October 2007

Toll-like receptor 4, F4/80 and pro-inflammatory cytokines in intestinal and mesenteric fat tissue of Crohn's disease ⬇️

scientific article published on January 26, 2013

Topical 5-azacytidine accelerates skin wound healing in rats.

scientific article published in September 2014

Topical Docosahexaenoic Acid (DHA) Accelerates Skin Wound Healing in Rats and Activates GPR120

scientific article published on 08 January 2016

Topical Topiramate Improves Wound Healing in an Animal Model of Hyperglycemia

scientific article published on 01 May 2019

Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial

scientific article

Topiramate treatment improves hypothalamic insulin and leptin signaling and action and reduces obesity in mice.

scientific article published on 20 July 2012

Tub Has a Key Role in Insulin and Leptin Signaling and Action In Vivo in Hypothalamic Nuclei ⬇️

scientific article published on September 10, 2012

Tumor necrosis factor-alpha activates signal transduction in hypothalamus and modulates the expression of pro-inflammatory proteins and orexigenic/anorexigenic neurotransmitters

scientific article published on 21 April 2006

Turning off a viral/lipid sensor improves type 2 diabetes

scientific article published on February 2014

Type 2 diabetes mellitus--an autoimmune disease?

scientific article

UCP2 protects hypothalamic cells from TNF-alpha-induced damage

scientific journal article

Unmanipulated native fat exposed to high-energy diet, but not autologous grafted fat by itself, may lead to overexpression of Ki67 and PAI-1.

scientific article published on 19 June 2015

Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity

scientific journal article

Verapamil-sensitive Ca2+ channel regulation of Th1-type proliferation of splenic lymphocytes induced by Walker 256 tumor development in rats.

scientific article published on 26 August 2006

We could be better if we ate better

scientific article published on 01 May 2020

[The hypothalamic control of feeding and thermogenesis: implications on the development of obesity]

scientific article published on 01 April 2006

beta3-Adrenergic-dependent and -independent mechanisms participate in cold-induced modulation of insulin signal transduction in brown adipose tissue of rats

scientific article

n-3 Fatty Acids Induce Neurogenesis of Predominantly POMC-Expressing Cells in the Hypothalamus

scientific article published on 28 October 2015

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