List of works - Shu Yang

A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling

scientific article published on 02 September 2020

A novelTARDBPinsertion/deletion mutation in the flail arm variant of amyotrophic lateral sclerosis

scientific article published on 16 March 2012

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

scientific article published on 04 December 2019

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

scientific article

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

scientific article published on 10 August 2017

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

scientific article published on 15 April 2016

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex.

scientific article

Cellular uptake of self-assembled cationic peptide-DNA complexes: multifunctional role of the enhancer chloroquine.

scientific article

Cyclin F: A component of an E3 ubiquitin ligase complex with roles in neurodegeneration and cancer.

scientific article published on 23 June 2017

DNA nanoclew templated spherical nucleic acids for siRNA delivery.

scientific article published on 23 March 2018

ERp57 is protective against mutant SOD1-induced cellular pathology in Amyotrophic Lateral Sclerosis.

scientific article published in February 2018

Evaluation of Skin Fibroblasts from Amyotrophic Lateral Sclerosis Patients for the Rapid Study of Pathological Features.

scientific article

Fused in sarcoma/translocated in liposarcoma: a multifunctional DNA/RNA binding protein.

scientific article published on 10 June 2010

Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming

scientific article published on 14 August 2019

Genetic and Pathological Assessment of hnRNPA1, hnRNPA2/B1, and hnRNPA3 in Familial and Sporadic Amyotrophic Lateral Sclerosis

scientific article published on 11 November 2017

Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice

scientific article published on 05 November 2019

Mutation analysis of the optineurin gene in familial amyotrophic lateral sclerosis

article

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

scientific article published on 29 August 2017

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43.

scientific article

Sensitive Detection of Motor Neuron Disease Derived Exosomal miRNA Using Electrocatalytic Activity of Gold‐Loaded Superparamagnetic Ferric Oxide Nanocubes

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.

scientific article

TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.

scientific article published on 25 June 2010

The characterization of a novel dendritic system for gene delivery by isothermal titration calorimetry

scientific article published on 01 January 2008

The mRNA-based reprogramming of fibroblasts from a SOD1E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007

scientific article published on 16 January 2020

Theme 3 In vitro experimental models

scientific article published on 01 November 2019

Ubiquilin 2: a component of the ubiquitin-proteasome system with an emerging role in neurodegeneration

scientific article published on 28 February 2014

Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations

List of works by Shu Yang

A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling

A novelTARDBPinsertion/deletion mutation in the flail arm variant of amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex.

Cellular uptake of self-assembled cationic peptide-DNA complexes: multifunctional role of the enhancer chloroquine.

Cyclin F: A component of an E3 ubiquitin ligase complex with roles in neurodegeneration and cancer.

DNA nanoclew templated spherical nucleic acids for siRNA delivery.

ERp57 is protective against mutant SOD1-induced cellular pathology in Amyotrophic Lateral Sclerosis.

Evaluation of Skin Fibroblasts from Amyotrophic Lateral Sclerosis Patients for the Rapid Study of Pathological Features.

Fused in sarcoma/translocated in liposarcoma: a multifunctional DNA/RNA binding protein.

Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming

Genetic and Pathological Assessment of hnRNPA1, hnRNPA2/B1, and hnRNPA3 in Familial and Sporadic Amyotrophic Lateral Sclerosis

Genetic and immunopathological analysis of CHCHD10 in Australian amyotrophic lateral sclerosis and frontotemporal dementia and transgenic TDP-43 mice

Mutation analysis of the optineurin gene in familial amyotrophic lateral sclerosis

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43.

Sensitive Detection of Motor Neuron Disease Derived Exosomal miRNA Using Electrocatalytic Activity of Gold‐Loaded Superparamagnetic Ferric Oxide Nanocubes

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.

TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.

The characterization of a novel dendritic system for gene delivery by isothermal titration calorimetry

The mRNA-based reprogramming of fibroblasts from a SOD1E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007

Theme 3 In vitro experimental models

Ubiquilin 2: a component of the ubiquitin-proteasome system with an emerging role in neurodegeneration

Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations