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List of works by Beat Schafer

A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300

scientific journal article

Alpha-parvalbumin reduces depolarization-induced elevations of cytosolic free calcium in human neuroblastoma cells.

scientific article published in June 1996

Analysis of CA(2+)-binding S100 proteins in human heart by HPLC-electrospray mass spectrometry

scientific article published on 01 December 1993

Anemia and survival in childhood acute lymphoblastic leukemia

scientific article published on 24 September 2008

Array comparative genomic hybridization reveals unbalanced gain of the MYCN region in Wilms tumors.

scientific article

BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma

scientific article published on 26 November 2021

Binding of Ca2+ and Zn2+ to Human Nuclear S100A2 and Mutant Proteins ⬇️

scientific article published on July 24, 1998

CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres

scientific article

Ca(2+)-binding proteins S100A6 and S100B in primary cutaneous melanoma.

scientific article

Ca2+ -dependent interaction of S100A1 with the sarcoplasmic reticulum Ca2+ -ATPase2a and phospholamban in the human heart

scientific article

Calcium regulation of Ndr protein kinase mediated by S100 calcium-binding proteins ⬇️

scientific article published on October 15, 1998

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma.

scientific article

Cell-based small-molecule compound screen identifies fenretinide as potential therapeutic for translocation-positive rhabdomyosarcoma

scientific article

Characterization of the human S100A12 (calgranulin C, p6, CAAF1, CGRP) gene, a new member of the S100 gene cluster on chromosome 1q21

scientific article

Characterization of the human and mouse cDNAs coding for S100A13, a new member of the S100 protein family

scientific article

Clonal expansion of a new MLL rearrangement in the absence of leukemia

scientific article published on 01 May 2005

Cloning and characterization of the human PAX7 promoter.

scientific article published on April 2000

Complementary DNA sequence and chromosomal mapping of a human proteoglycan-binding cell-adhesion protein (dermatopontin).

scholarly article

Differential expression of S100B and S100A6(1) in the human fetal and aged cerebral cortex.

scientific article published in February 2000

Differential expression of the Ca2+ binding S100A6 protein in normal, preneoplastic and neoplastic colon mucosa

scientific article published on 01 May 2000

Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia

scientific article published on 23 September 2004

Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays

scientific article published on 01 July 2003

Expression of Ca(2+)-binding proteins of the S100 family in malignant human breast-cancer cell lines and biopsy samples

scientific article published on 01 June 1994

Expression of intracellular calcium-binding proteins in cultured skin fibroblasts from Alzheimer and normal aged donors.

scientific article published on September 1994

FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.

scientific article

Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma

scientific article published on 06 March 2020

Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1.

scientific article

Generation of a novel rtTA transgenic mouse to induce time-controlled, tissue-specific alterations in Pax2-expressing cells.

scientific article published on 23 September 2011

Helicase CHD4 is an epigenetic coregulator of PAX3-FOXO1 in alveolar rhabdomyosarcoma

scientific article published on 17 October 2016

Human alpha and beta parvalbumins. Structure and tissue-specific expression

scientific article

Human ferrochelatase: a novel mutation in patients with erythropoietic protoporphyria and an isoform caused by alternative splicing

scientific article published on 01 April 1995

Human recombinant alpha-parvalbumin and nine mutants with individually inactivated calcium- and magnesium-binding sites: biochemical and immunological properties.

scientific article published in October 1996

Identification of a rhabdomyosarcoma targeting peptide by phage display with sequence similarities to the tumour lymphatic-homing peptide LyP-1.

scientific article

Identification of novel DNA binding sites recognized by the transcription factor mPOU (POU6F1).

scientific article

Immunohistochemical localization of S100A1 and S100A6 in postnatally developing salivary glands of rats

scientific article published on 01 December 1998

Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

scientific article published on November 1996

Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance

scientific article

Interfering with Hedgehog Pathway: New Avenues for Targeted Therapy in Rhabdomyosarcoma

scientific article published on 05 May 2015

Inv(11)(p13p15) and myf-3(MyoD1) in a malignant extrarenal rhabdoid tumor of a premature newborn

scientific article published on 01 October 2000

Late MRD response determines relapse risk overall and in subsets of childhood T-cell ALL: results of the AIEOP-BFM-ALL 2000 study

scientific article

Localization of Ca 2+ -binding S100 proteins in epithelial tumours of the skin ⬇️

scientific article published on January 1, 1998

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

scientific article published on 30 May 2007

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

scientific article published on 31 January 2008

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes

scientific article

Molecular cloning and characterization of the human S100A14 gene encoding a novel member of the S100 family

scientific article

Multidisciplinary management of childhood sarcoma: time to expand ⬇️

scientific article published on 01 August 2010

New insights to the MLL recombinome of acute leukemias

scientific article

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

scientific article published on 10 November 2020

NuRD subunit CHD4 regulates super-enhancer accessibility in Rhabdomyosarcoma and represents a general tumor dependency ⬇️

scientific article published on 03 August 2020

PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.

scientific article published on 22 August 2015

PLK1 phosphorylates PAX3-FOXO1, the inhibition of which triggers regression of alveolar Rhabdomyosarcoma.

scientific article

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

scientific article published on 15 September 2020

Phosphorylation regulates transcriptional activity of PAX3/FKHR and reveals novel therapeutic possibilities.

scientific article published in May 2008

Prediction of chromosomal aneuploidy from gene expression data.

scientific article

Preferred analysis methods for single genomic regions in RNA sequencing revealed by processing the shape of coverage.

scientific article published on 30 December 2011

Prenatal origin of separate evolution of leukemia in identical twins.

scientific article published on October 2004

Prognostic significance of the Ca(2+) binding protein S100A2 in laryngeal squamous-cell carcinoma.

scientific article published in July 2000

Proteasomal Degradation of the EWS-FLI1 Fusion Protein Is Regulated by a Single Lysine Residue.

scientific article published on 8 November 2016

Purification and Cation Binding Properties of the Recombinant Human S100 Calcium-binding Protein A3, an EF-hand Motif Protein with High Affinity for Zinc ⬇️

scientific article published on September 8, 1995

Purification and characterization of the recombinant human calcium-binding S100 proteins CAPL and CACY

scientific journal article

Rapid molecular diagnosis of erythropoietic protoporphyria among Swiss patients

scientific article published on 01 October 1998

Reduced-Intensity Delayed Intensification in Standard-Risk Pediatric Acute Lymphoblastic Leukemia Defined by Undetectable Minimal Residual Disease: Results of an International Randomized Trial (AIEOP-BFM ALL 2000).

scientific article published on 17 November 2017

Repression of the candidate tumor suppressor gene S100A2 in breast cancer is mediated by site-specific hypermethylation ⬇️

scientific article published on October 1, 1997

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

scientific article

S100 alpha, CAPL, and CACY: molecular cloning and expression analysis of three calcium-binding proteins from human heart

scientific article (publication date: 27 October 1992)

S100 protein translocation in response to extracellular S100 is mediated by receptor for advanced glycation endproducts in human endothelial cells

scientific article

S100 proteins in Corpora amylacea from normal human brain.

scientific article

S100A2, a Putative Tumor Suppressor Gene, Regulates In Vitro Squamous Cell Carcinoma Migration

article

Selective association of S100A6 (calcyclin)-immunoreactive astrocytes with the tangential migration pathway of subventricular zone cells in the rat ⬇️

scientific article published on December 19, 1997

Structural insight into human Zn(2+)-bound S100A2 from NMR and homology modeling.

scientific article

Subtype and prognostic classification of rhabdomyosarcoma by immunohistochemistry

scientific article published on 03 January 2006

Systematic Analysis of Molecular Defects in the Ferrochelatase Gene from Patients with Erythropoietic Protoporphyria ⬇️

scientific article published on June 1, 1998

Targeting hedgehog signaling reduces self-renewal in embryonal rhabdomyosarcoma

scientific article

Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma

scientific article published on 25 November 2015

The LIM-only protein FHL2 is a negative regulator of E4F1

scientific article

The MLL recombinome of acute leukemias

scientific article published on 01 May 2006

The MLL recombinome of acute leukemias in 2013.

scientific article

The MLL recombinome of acute leukemias in 2017.

scientific article published on 13 July 2017

The PAX5 oncogene is expressed in N-type neuroblastoma cells and increases tumorigenicity of a S-type cell line.

scientific article published on 20 May 2004

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.

scientific article

The S100 family of EF-hand calcium-binding proteins: functions and pathology

scientific article

The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity.

scientific article published on 7 June 2005

The human paired domain gene PAX7 (Hup1) maps to chromosome 1p35-1p36.2

scientific article

The in vivo form of the murine class VI POU protein Emb is larger than that encoded by previously described transcripts.

scientific article published on May 2004

The primary structure of chicken B-creatine kinase and evidence for heterogeneity of its mRNA.

scientific article

The proprotein convertase furin is required to maintain viability of alveolar rhabdomyosarcoma cells

scientific article published on 27 August 2016

The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease

scientific article

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

scientific article

Transcriptional activation of the human S100A2 promoter by wild-type p53

scientific article published on 01 February 1999

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

scientific article published in Scientific Reports

Unpeaceful roles of mutant PAX proteins in cancer

scientific article

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells

scientific article published on 08 January 2021

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.

scientific article

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