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List of works by Elisabeth de Vries

(111)In-trastuzumab scintigraphy in HER2-positive metastatic breast cancer patients remains feasible during trastuzumab treatment.

scientific article

(89)Zr-trastuzumab PET visualises HER2 downregulation by the HSP90 inhibitor NVP-AUY922 in a human tumour xenograft

scientific article

111Indium-trastuzumab visualises myocardial human epidermal growth factor receptor 2 expression shortly after anthracycline treatment but not during heart failure: a clue to uncover the mechanisms of trastuzumab-related cardiotoxicity.

scientific article published on 24 August 2007

18F-Fluoroestradiol Tumor Uptake Is Heterogeneous and Influenced by Site of Metastasis in Breast Cancer Patients

scientific article published on 30 March 2018

18F-dihydroxyphenylalanine PET in patients with biochemical evidence of medullary thyroid cancer: relation to tumor differentiation.

scientific article published in April 2008

5-Fluorouracil/leucovorin/interferon alpha-2a in patients with advanced colorectal cancer. Effects of maintenance therapy on remission duration

scientific article published on 01 March 1995

6-[F-18]Fluoro-L-dihydroxyphenylalanine positron emission tomography is superior to conventional imaging with (123)I-metaiodobenzylguanidine scintigraphy, computer tomography, and magnetic resonance imaging in localizing tumors causing catecholamine

scientific article published on 21 July 2009

89Zr-Bevacizumab PET Visualizes Disease Manifestations in Patients with von Hippel-Lindau Disease.

scientific article published on 12 May 2016

89Zr-Bevacizumab PET: Potential Early Indicator of Everolimus Efficacy in Patients with Metastatic Renal Cell Carcinoma

scientific article published on 12 January 2017

89Zr-Lumretuzumab PET Imaging before and during HER3 Antibody Lumretuzumab Treatment in Patients with Solid Tumors.

scientific article published on 21 July 2017

89Zr-Onartuzumab PET imaging of c-MET receptor dynamics.

scientific article

89Zr-atezolizumab imaging as a non-invasive approach to assess clinical response to PD-L1 blockade in cancer

scientific article published on 26 November 2018

89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922.

scientific article published on 15 April 2010

89Zr-bevacizumab PET visualizes heterogeneous tracer accumulation in tumor lesions of renal cell carcinoma patients and differential effects of antiangiogenic treatment.

scientific article published on 4 December 2014

89Zr-labeled Bispecific T-cell Engager AMG 211 PET Shows AMG 211 Accumulation in CD3-rich Tissues and Clear, Heterogeneous Tumor Uptake

scientific article published on 11 February 2019

89Zr-labeled anti-PD-L1 CX-072 PET imaging in human xenograft and syngeneic tumors

scientific article published on 01 February 2019

89Zr-mAb3481 PET for HER3 tumor status assessment during lapatinib treatment

scientific article

89Zr-trastuzumab PET supports clinical decision making in breast cancer patients, when HER2 status cannot be determined by standard work up

scientific article published on 30 July 2018

89Zr-trastuzumab and 89Zr-bevacizumab PET to evaluate the effect of the HSP90 inhibitor NVP-AUY922 in metastatic breast cancer patients.

scientific article

99mTc-Sestamibi scanning with SDZ PSC 833 as a functional detection method for resistance modulation in patients with solid tumours

scientific article published on 01 May 1999

99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein ⬇️

scientific article published on January 1, 1998

A Conversation Between Elisabeth de Vries and Johannes Czernin

scientific article published on 01 October 2019

A bioinformatical and functional approach to identify novel strategies for chemoprevention of colorectal cancer.

scientific article published on 10 January 2011

A case of localized Castleman's disease with systemic involvement: treatment and pathogenetic aspects

scientific article published on 01 July 1996

A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma.

scientific article

A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma

article

A multi-center prospective phase II study of high-dose chemotherapy in germ-cell cancer patients relapsing from complete remission

scientific article published on 01 December 1999

A new in vitro assay for quantitation of chemotherapy-induced mucositis.

scientific article

A patient education program for a continuous infusion regimen on an outpatient basis

scientific article published on 01 August 1987

A phase 1b study evaluating the effect of elacestrant treatment on estrogen receptor availability and estradiol binding to the estrogen receptor in metastatic breast cancer lesions using 18F-FES PET/CT imaging

scientific article published on 11 September 2020

A phase I and pharmacokinetic study of intraperitoneal topotecan

scientific article

A phase I and pharmacokinetic study with 21-day continuous infusion of epirubicin

scientific article published on 01 September 1987

A phase I dose escalation study of BIBW 2992, an irreversible dual inhibitor of epidermal growth factor receptor 1 (EGFR) and 2 (HER2) tyrosine kinase in a 2-week on, 2-week off schedule in patients with advanced solid tumours

scientific article published on 15 January 2008

A phase I pharmacokinetic study of 21-day continuous infusion mitoxantrone.

scientific article

A phase I study of 1,2-diamminomethyl-cyclobutane-platinum (II)-lactate (D-19466; lobaplatin) administered daily for 5 days.

scientific article

A phase I study of a new polyamine biosynthesis inhibitor, SAM486A, in cancer patients with solid tumours.

scientific article published on September 2000

A phase I study of lobaplatin (D-19466) administered by 72 h continuous infusion.

scientific article

A phase I study with MAG-camptothecin intravenously administered weekly for 3 weeks in a 4-week cycle in adult patients with solid tumours

scientific article published on June 2004

A phase I-II study of 14-days continuous infusion of 5-fluorouracil with weekly bolus leucovorin in metastatic colorectal carcinoma

scientific article published on 01 January 1992

A phase I-II study with intraperitoneal cisplatin plus systemic etoposide in patients with minimal residual ovarian cancer.

scientific article

A phase II and pharmacokinetic study with oral piritrexim for metastatic breast cancer.

scientific article

A phase II study of a 21 day continuous infusion schedule with epirubicin in advanced gastric cancer

scientific article published on 01 October 1989

A phase II study of carboplatin and vincristine in previously treated patients with small-cell lung cancer

scientific article published on 01 January 1989

A phase Ib study of the VEGF receptor tyrosine kinase inhibitor tivozanib and modified FOLFOX-6 in patients with advanced gastrointestinal malignancies.

scientific article

A progress report on the outpatient treatment of patients with advanced renal cell carcinoma using subcutaneous recombinant interleukin-2

scientific article published on 01 December 1993

A prolonged methoxymorpholino doxorubicin (PNU-152243 or MMRDX) infusion schedule in patients with solid tumours: a phase 1 and pharmacokinetic study.

scientific article

A quantitative reverse transcriptase polymerase chain reaction-based assay to detect carcinoma cells in peripheral blood ⬇️

scientific article published on January 1, 1997

A randomized phase II study of paclitaxel with carboplatin +/- amifostine as first line treatment in advanced ovarian carcinoma.

scientific article published in April 2005

A randomized, double-blind, multicentre study comparing daily 2 and 5 mg of tropisetron for the control of nausea and vomiting induced by low-dose cisplatin- or non-cisplatin-containing chemotherapy

scientific article published on 01 July 1996

A review of bispecific antibodies and antibody constructs in oncology and clinical challenges

scientific article published on 24 April 2019

A review on CXCR4/CXCL12 axis in oncology: no place to hide.

scientific article published on 09 June 2012

A robust ex vivo model for evaluation of induction of apoptosis by rhTRAIL in combination with proteasome inhibitor MG132 in human premalignant cervical explants

scientific article published in September 2008

A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS).

scientific article

A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS): Table 6:

article

ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance.

scientific article published on 23 March 2007

ADCC responses and blocking of EGFR-mediated signaling and cell growth by combining the anti-EGFR antibodies imgatuzumab and cetuximab in NSCLC cells.

scientific article published on 17 April 2017

APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.

scientific article

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.

scientific article published on February 1999

ATP-binding cassette (ABC) transporters in normal and pathological lung

scientific article

ATR inhibition preferentially targets homologous recombination-deficient tumor cells.

scientific article published in September 2014

Absence of relation between nutritional parameters and renal function in non-seminomatous testicular cancer patients

scientific article published on 01 January 1988

Absence of the influence of age on remission rate and duration of remission in a group of thirty-four patients with acute myeloid leukaemia

scientific article published on 01 January 1980

Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells.

scientific article published on July 1998

Activity of (7) anthracycline related compounds in an doxorubicin sensitive human small cell lung cancer line and its doxorubicin resistant descendant. Activity of doxorubicin, daunorubicin, 4-deoxyrubicin, 4-demethoxydaunorubicin, detorubicin, 4'-e

scientific article

Acute and long-term toxicity following radiotherapy alone or in combination with chemotherapy for locally advanced cervical cancer.

scientific article published on December 2003

Acute-phase response in patients given rhIL-3 after chemotherapy

scientific article published on 01 June 1992

Additive value of transoesophageal echocardiography in the visualization of carcinoid heart disease

scientific article published on 01 August 1992

Advanced ovarian cancer. Drug resistance, supportive care and dose intensity.

scientific article published on January 1993

Alpha-fetoprotein-lectin binding as a marker of tumour activity or liver damage ⬇️

scientific article published on January 1, 1990

Alternating cycles of PVB and BEP in the treatment of patients with advanced seminoma ⬇️

scientific article published on January 1, 1991

An in vitro model for purging of tumour cells from ovarian tissue.

scientific article published on 7 April 2004

An oncological view on the blood-testis barrier.

scientific article

Analysis of the entire HLA region in susceptibility for cervical cancer: a comprehensive study.

scientific article published in August 2005

Analyzing longitudinal data with patients in different disease states during follow-up and death as final state.

scientific article

Androgen and Estrogen Receptor Imaging in Metastatic Breast Cancer Patients as a Surrogate for Tissue Biopsies

scientific article

Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer

scientific article published on 09 September 2018

Angiotensin II-Receptor Inhibition With Candesartan to Prevent Trastuzumab-Related Cardiotoxic Effects in Patients With Early Breast Cancer: A Randomized Clinical Trial.

scientific article published on 23 June 2016

Antibody positron emission tomography imaging in anticancer drug development.

scientific article published on 16 March 2015

Anticancer drugs aimed at E6 and E7 activity in HPV-positive cervical cancer.

scientific article published on February 2012

Antisense of oligonucleotides and the inhibition of oncogene expression

scientific article published on 01 January 1993

Apoptosis induction by sennoside laxatives in man; escape from a protective mechanism during chronic sennoside use?

scientific article published on 01 August 2001

Assessment of apoptosis by M30 immunoreactivity and the correlation with morphological criteria in normal colorectal mucosa, adenomas and carcinomas

scientific article published on 01 January 2004

Assessment of estrogen receptor expression in epithelial ovarian cancer patients using 16α-18F-fluoro-17β-estradiol PET/CT.

scientific article

Ataxia following docetaxel infusion.

scientific article published on August 1997

Automated mass spectrometric analysis of urinary and plasma serotonin.

scientific article

Automated on-line solid-phase extraction coupled with HPLC for measurement of 5-hydroxyindole-3-acetic acid in urine.

scientific article published on 14 July 2005

Balancing treatment efficacy, toxicity and complication risk in elderly patients with metastatic renal cell carcinoma

scientific article

Better yield of (18)fluorodeoxyglucose-positron emission tomography in patients with metastatic differentiated thyroid carcinoma during thyrotropin stimulation.

scientific article published in May 2002

Bevacizumab-induced normalization of blood vessels in tumors hampers antibody uptake

scientific article published on 11 April 2013

Bevacizumab-induced vessel normalization hampers tumor uptake of antibodies--response.

scientific article published on 21 November 2013

Beware of amenorrhea during tamoxifen: it may be a wolf in sheep's clothing

scientific article published on 01 August 2007

Biodistribution and PET Imaging of Labeled Bispecific T Cell-Engaging Antibody Targeting EpCAM.

scientific article published on 4 February 2016

Biodistribution of a CD3/EpCAM bispecific T-cell engager is driven by the CD3 arm

scientific article published on 13 April 2020

Bleeding prophylaxis in autologous bone marrow transplantation for solid tumors. Comparison of cryopreserved autologous and fresh allogeneic single-donor platelets

scientific article published on 01 January 1989

Bleomycin-Induced Pulmonary Changes on Restaging Computed Tomography Scans in Two Thirds of Testicular Cancer Patients Show No Correlation With Fibrosis Markers.

scientific article published on 21 June 2016

Bone marrow toxicity of cyclophosphazenes is related to their structure and the treatment schedule

scientific article published on 01 February 1986

Bone metastases in carcinoid tumors: clinical features, imaging characteristics, and markers of bone metabolism.

scientific article

Breaking the DNA damage response to improve cervical cancer treatment.

scientific article

Breast cancer studies in The Netherlands

scientific article published on 01 August 1996

Broad phase II and pharmacokinetic study of methoxy-morpholino doxorubicin (FCE 23762-MMRDX) in non-small-cell lung cancer, renal cancer and other solid tumour patients ⬇️

scientific article published on January 1, 1998

CA-125 in ovarian cancer: relation between half-life, doubling time and survival.

scientific article

CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment

scientific article published on January 2015

CXCR4 inhibition enhances radiosensitivity, while inducing cancer cell mobilization in a prostate cancer mouse model

scientific article published on 26 August 2014

CXCR4 inhibition with AMD3100 sensitizes prostate cancer to docetaxel chemotherapy

scientific article published on August 2012

Calcium affects biomarkers of colon carcinogenesis after right hemicolectomy.

scientific article

Calcium and colorectal epithelial cell proliferation.

scientific article published in November 1996

Calcium and the Prevention of Colon Cancer ⬇️

scientific article published on January 1, 1991

Calcium and vitamin D: possible protective agents against colorectal cancer?

scientific article

Calcium or resistant starch does not affect colonic epithelial cell proliferation throughout the colon in adenoma patients: a randomized controlled trial.

scientific article published on January 2002

Calculating optimal surveillance for detection of von Hippel-Lindau-related manifestations.

scientific article

Cancer-drug induced insulin resistance: innocent bystander or unusual suspect

scientific article published on 18 February 2015

Carbon-11-labeled daunorubicin and verapamil for probing P-glycoprotein in tumors with PET.

scientific article published on September 1996

Carboplatin in the treatment of ovarian carcinoma; as effective and less toxic in comparison with cisplatin

scientific article

Carcinoid crisis after injection of 6-18F-fluorodihydroxyphenylalanine in a patient with metastatic carcinoid.

scientific article published in July 2005

Carcinoid heart disease

scientific article published on 01 June 2003

Carcinoid tumors

scientific article published on 01 August 1999

Carcinoid tumors; current viewpoints of biochemical and endocrine aspects, diagnosis and treatment

scientific article published in May 1992

Cardiotoxicity associated with the use of trastuzumab in breast cancer patients.

scientific article published on December 2007

Cardiotoxicity from intensive chemotherapy combined with radiotherapy in breast cancer

scientific article

Cardiovascular morbidity after radiotherapy or chemoradiation in patients with cervical cancer

scientific article published on 29 March 2010

Catecholamine-synthesizing enzymes in carcinoid tumors and pheochromocytomas

scientific article published in April 2003

Cell biological markers of drug resistance in ovarian carcinoma.

scientific article published on August 1995

Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell lines.

scientific article published on April 1995

Changes in body composition after childhood cancer treatment: impact on future health status--a review.

scientific article published on 6 March 2007

Characterization of a human small cell lung carcinoma cell line with acquired resistance to cis-diamminedichloroplatinum(II) in vitro.

scientific article published on December 1988

Characterization of three small cell lung cancer cell lines established from one patient during longitudinal follow-up.

scientific article published on December 1988

Chemo-immunotherapy of ovarian cancer in a murine tumour model

scientific article published on 01 July 2000

Chemotherapy dose-escalation with hemopoietic growth factor support in ovarian cancer.

scientific article published on December 1994

Chemotherapy induces death receptor 5 in epithelial ovarian carcinoma.

scientific article published in March 2004

Chemotherapy with maximally tolerable doses of VP 16-213 and cyclophosphamide followed by autologous bone marrow transplantation for the treatment of relapsed or refractory germ cell tumors.

scientific article

Children born after their fathers had been treated with chemotherapy for testicular cancer

scientific article published on 01 January 1990

Cigarette smoke extract affects functional activity of MRP1 in bronchial epithelial cells

scientific article

Cisplatin and platinum pharmacokinetics during hyperthermic isolated limb perfusion for human tumours of the extremities ⬇️

scientific article published on June 1, 1992

Cisplatin-induced DNA-platination in experimental dorsal root ganglia neuronopathy

scientific article published on 01 December 1999

Clinical cancer research 2001: new agents and therapies.

scientific article

Clinical potential of inhibitors of survival pathways and activators of apoptotic pathways in treatment of cervical cancer: changing the apoptotic balance.

scientific article

Clinical relevance of transforming growth factor alpha, epidermal growth factor receptor, p53, and Ki67 in colorectal liver metastases and corresponding primary tumors

scientific article published on 01 October 1998

Clinical role of GM-CSF in neutrophil recovery in relation to health care parameters.

scientific article published on September 1996

Clinical trial design for systemic agents in patients with brain metastases from solid tumours: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group.

scientific article published in January 2018

Clinical, toxicological and pharmaceutical aspects of the antineoplastic drug taxol: a review.

scientific article published on January 1994

Clinical-grade N-(4-[18F]fluorobenzoyl)-interleukin-2 for PET imaging of activated T-cells in humans

scientific article published on 17 July 2019

Colorectal cancer and theCHEK2 1100delC mutation

article

Combination chemotherapy for acute lymphocytic leukaemia in 25 adults

scientific article published on 01 March 1982

Combination therapy with cisplatin: modulation of activity and tumour sensitivity.

scientific article

Combined treatment with goserelin and tamoxifen in patients with advanced chemotherapy resistant ovarian cancer

scientific article published on 01 July 1999

Combinedin vitro modulation of adriamycin resistance ⬇️

scientific article published on October 21, 1991

Combining 6-fluoro-[18F]l-dihydroxyphenylalanine and [18F]fluoro-2-deoxy-d-glucose positron emission tomography for distinction of non-carcinoid malignancies in carcinoid patients.

scientific article published on 22 May 2009

Comparative Assessment of Clinical Benefit Using the ESMO-Magnitude of Clinical Benefit Scale Version 1.1 and the ASCO Value Framework Net Health Benefit Score

scientific article published on 17 December 2018

Comparative biodistribution analysis across four different Zr-monoclonal antibody tracers-The first step towards an imaging warehouse

scientific article published on 30 July 2018

Comparison of the kinetics of active efflux of 99mTc-MIBI in cells with P-glycoprotein-mediated and multidrug-resistance protein-associated multidrug-resistance phenotypes

scientific article published on 01 February 1998

Complete in vivo reversal of P‐glycoprotein pump function in the blood‐brain barrier visualized with positron emission tomography ⬇️

scientific article published on August 1, 1998

Complications of midgut carcinoid tumors and carcinoid syndrome.

scientific article published in January 2004

Concurrent chemo- and radiotherapy in patients with locally advanced carcinoma of the cervix

scientific article published on 01 July 1996

Consensus on the use of neutrophil-stimulating hematopoietic growth factors in clinical practice: an international viewpoint

scientific article published on 01 May 1997

Consideration of breast cancer subtype in targeting the androgen receptor

scientific article published on 08 May 2019

Considerations on absence of 68Ga-DOTA-F(ab')2-trastuzumab tracer uptake in HER2-overexpressing tumor lesions

scientific article published on 01 July 2014

Considering the biology of late recurrences in selecting patients for extended endocrine therapy in breast cancer

scientific article published on 26 July 2018

Constrictive pericarditis after high-dose chemotherapy

scientific article published on 01 November 1997

Continuous carboplatin infusion during 6 weeks' radiotherapy in locally inoperable non-small-cell lung cancer: a phase I and pharmacokinetic study.

scientific article

Continuous infusion of chemotherapy on an outpatient basis via a totally implanted venous access port

scientific article published on 01 January 1991

Continuously infused carboplatin used as radiosensitizer in locally unresectable non-small-cell lung cancer: a multicenter phase III study

scientific article published on 01 March 2004

Conversion of the prodrug etoposide phosphate to etoposide in gastric juice and bile ⬇️

scientific article published on January 1, 1997

Correcting the Conclusion in a Study of Frameworks for Measurement of Absolute or Relative Clinical Survival Benefit

scientific article published on 17 October 2019

Correspondence re: C. G. Ferreira et al., Apoptosis: target of cancer therapy. Clin. Cancer Res., 8: 2024-2034, 2002

scientific article published on 01 February 2003

Corrigendum to "Dopamine and serotonin regulate tumor behavior by affecting angiogenesis" [Drug Resist. Updat. 17 (2014) 96-104]

scientific article published on 30 July 2020

Cross-cohort gut microbiome associations with immune checkpoint inhibitor response in advanced melanoma

scientific article published on 28 February 2022

Current state of liposome-complexed drugs in the treatment of cancer patients

scientific article published on 01 June 1992

Cyclophosphamide and VP 16-213 with autologous bone marrow transplantation. A dose escalation study.

scientific article

Dacarbazine (DTIC), human recombinant interferon alpha 2a (Roferon) and 5-fluorouracil for disseminated malignant melanoma ⬇️

scientific article published on February 1, 1992

Dacarbazine (DTIC)-based chemotherapy or chemoimmunotherapy of patients with disseminated malignant melanoma ⬇️

scientific article published on October 1, 1994

Debulking surgery for ovarian epithelial cancer performed by a gynaecological oncologist improved survival compared with less specialised surgeons

scientific article published on 16 May 2006

Decalcification of Breast Cancer Bone Metastases With EDTA Does Not Affect ER, PR, and HER2 Results

scientific article published on 01 October 2019

Deficiencies in fat-soluble vitamins in long-term users of somatostatin analogue.

scientific article published on 7 October 2010

Deletion of the multidrug resistance protein MRP1 gene in acute myeloid leukemia: the impact on MRP activity

scientific article published on 01 June 2000

Delirium after interleukin-2 and alpha-interferon therapy for renal cell carcinoma

scientific article published on 01 September 2001

Design and conduct of early clinical studies of immunotherapy: Recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies 2019 (MDICT)

scientific article published on 21 February 2020

Detection of DNA cross-links in tumor cells with the ethidium bromide fluorescence assay

scientific article published on 01 April 1986

Detection of anthracycline-induced cardiotoxicity.

scientific article

Detection of micrometastatic breast cancer by means of real time quantitative RT-PCR and immunostaining in perioperative blood samples and sentinel nodes.

scientific article

Determination of epirubicin and its metabolite epirubicinol in saliva and plasma by HPLC.

scientific article published in August 2003

Development and evaluation of interleukin-2 derived radiotracers for PET imaging of T-cells in mice

scientific article published on 28 February 2020

Development of a radioiodinated apoptosis-inducing ligand, rhTRAIL, and a radiolabelled agonist TRAIL receptor antibody for clinical imaging studies ⬇️

scientific article published on April 1, 2012

Development of an optimal sampling strategy for clinical pharmacokinetic studies of the novel anthracycline disaccharide analogue MEN-10755.

scientific article published on 7 April 2004

Development, preclinical safety, formulation, and stability of clinical grade bevacizumab-800CW, a new near infrared fluorescent imaging agent for first in human use

scientific article published on 12 May 2016

Diagnostic I-131 scintigraphy in patients with differentiated thyroid cancer: no additional value of higher scan dose.

scientific article published in December 2004

Dietary influences on plasma and urinary metanephrines: implications for diagnosis of catecholamine-producing tumors.

scientific article published on 30 June 2009

Difference in CXCR4 expression between sporadic and VHL-related hemangioblastoma

scientific article published on 26 February 2016

Different type of DNA damage caused by three aziridinyl substituted cyclophosphazenes in a human small cell lung carcinoma cell line.

scientific article published on June 1986

Differential effects of all-trans-retinoic acid, docosahexaenoic acid, and hexadecylphosphocholine on cisplatin-induced cytotoxicity and apoptosis in a cisplantin-sensitive and resistant human embryonal carcinoma cell line.

scientific article published on January 1998

Differential expression of DNA topoisomerase II alpha and -beta in P-gp and MRP-negative VM26, mAMSA and mitoxantrone-resistant sublines of the human SCLC cell line GLC4.

scientific article

Differential modulation of the TRAIL receptors and the CD95 receptor in colon carcinoma cell lines.

scientific article published on July 2003

Differential regulation of IL-6 promoter activity in a human ovarian-tumor cell line transfected with various p53 mutants: involvement of AP-1.

scientific article published on April 1999

Differentiated thyroid carcinoma in the elderly.

scientific article

Differentiated thyroid carcinoma: a polygenic disease.

scientific article

Diffuse alveolar hemorrhage in autologous bone marrow transplant recipients

scientific article published on 01 February 1991

Diminished expression of multidrug resistance-associated protein 1 (MRP1) in bronchial epithelium of COPD patients

scientific article published on 27 October 2006

Discrepancy between ultrasonography and hysteroscopy and histology of endometrium in postmenopausal breast cancer patients using tamoxifen

scientific article published on 01 April 1999

Discriminating capacity of indole markers in the diagnosis of carcinoid tumors

scientific article published on 01 October 2000

Don't blaze the trailblazer TRAIL too early.

scientific article published in December 2000

Dopamine and serotonin regulate tumor behavior by affecting angiogenesis

scientific article published on 22 September 2014

Dose escalation of dacarbazine combined with interferon alpha-2a, G-CSF and ondansetron in patients with metastatic melanoma

scientific article published on May 1, 1994

Dose intensity of standard adjuvant CMF with granulocyte colony-stimulating factor for premenopausal patients with node-positive breast cancer

scientific article published on 01 July 1996

Dose intensive therapy in breast cancer.

scientific article

Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines ⬇️

scientific article published on October 1, 2010

Drug resistance-associated markers P-glycoprotein, multidrug resistance-associated protein 1, multidrug resistance-associated protein 2, and lung resistance protein as prognostic factors in ovarian carcinoma.

scientific article published in October 1999

Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis.

scientific article

Duodenal 7-ethoxycoumarin-o-deethylase activity in colon-cancer patients

scientific article published on 01 July 1993

Dysplasia in fundic gland polyps is associated with nuclear beta-catenin expression and relatively high cell turnover rates.

scientific article published in September 2003

EHA evaluation of the ESMO-Magnitude of Clinical Benefit Scale version 1.1 (ESMO-MCBS v1.1) for haematological malignancies

scientific article published on 01 January 2020

ESMO - Magnitude of Clinical Benefit Scale V.1.0 questions and answers

scientific article

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016

scientific article (publication date: 2016)

ESMO-MCBS: setting the record straight

scientific article published on 01 April 2019

ESMO-Magnitude of Clinical Benefit Scale version 1.1.

scientific article published on 4 September 2017

EUS is superior for detection of pancreatic lesions compared with standard imaging in patients with multiple endocrine neoplasia type 1.

scientific article published in January 2015

Early detection of anthracycline induced cardiotoxicity in asymptomatic patients with normal left ventricular systolic function: autonomic versus echocardiographic variables

scientific article

Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells.

scientific article

Effect of interferon and 5-fluorouracil on serum VEGF levels in neuroendocrine tumours

scientific article published on 01 January 2008

Effect of low-dose oral etoposide on serum CA-125 in patients with advanced epithelial ovarian cancer

scientific article published on 01 August 1997

Effect of novobiocin on cisplatin cytotoxicity and DNA interstrand cross-link formation in a cisplatin-resistant, small-cell lung carcinoma cell line.

scientific article published on January 1993

Effect of partial liver resection on tumour growth.

scientific article published on July 1996

Effect of vemurafenib on a V600R melanoma brain metastasis

scientific article published on 6 March 2013

Effects of an inducible anti-sense c-myc gene transfer in a drug-resistant human small-cell-lung-carcinoma cell line.

scientific article

Effects of c-myc oncogene modulation on differentiation of human small cell lung carcinoma cell lines.

scientific article published on January 1998

Effects of hematopoietic growth factors on chemotherapy-induced myelosuppression

scientific article published on September 1, 1992

Effects of hemicolectomy on bile acid metabolism in relation to colon carcinogenesis in man

scientific article published on 01 July 1997

Effects of impaired renal function on the pharmacokinetics and toxicity of i.v. ZD9331, a novel non-polyglutamated thymidylate synthase inhibitor, in adult patients with solid tumors.

scientific article published in July 2002

Effects of interleukin-3 after chemotherapy for advanced ovarian cancer.

scientific article

Effects of ondansetron on gastrointestinal symptoms in carcinoid syndrome

scientific article published on 01 July 1998

Effects of peripheral stem-cell or bone-marrow reinfusion on peripheral serotonin metabolism

scientific article published on 01 January 1999

Effects of supplemental dietary calcium on quantitative and qualitative fecal fat excretion in man

article

Elevated hTERT mRNA levels: A potential determinant of bronchial squamous cell carcinoma (in situ).

scientific article published on April 2004

Elevated urinary free and deconjugated catecholamines after consumption of a catecholamine-rich diet.

scientific article published on 9 April 2010

Emerging Opportunities for c-MET Visualization in the Clinic.

scientific article

Endodermal sinus tumor of the ovary during pregnancy: a case report

scientific article published on 01 February 1991

Endothelial cell effects of cytotoxics: balance between desired and unwanted effects.

scientific article published in October 2004

Endothelial damage in long-term survivors of childhood cancer

scientific article published on 23 September 2013

Endotoxin increases plasma soluble tumor necrosis factor-related apoptosis-inducing ligand level mediated by the p38 mitogen-activated protein kinase signaling pathway.

scientific article published in August 2004

Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression ⬇️

scientific article published on January 1, 1992

Enhanced antitumor efficacy of a DR5-specific TRAIL variant over recombinant human TRAIL in a bioluminescent ovarian cancer xenograft model.

scientific article published on 10 March 2009

Enhancement of cisplatin and etoposide cytotoxicity after all-trans retinoic-acid-induced cellular differentiation of a murine embryonal carcinoma cell line.

scientific article published on September 1993

Enteral nutrition by nasogastric tube in adult patients treated with intensive chemotherapy for acute leukemia

scientific article published on 01 June 1982

Epithelial cell proliferation in the sigmoid colon of patients with adenomatous polyps increases during oral calcium supplementation

scientific article

Evaluation of a totally implanted venous access port and portable pump in a continuous chemotherapy infusion schedule on an outpatient basis

scientific article published on 01 November 1987

Evaluation of long term cardiotoxicity after epirubicin containing adjuvant chemotherapy and locoregional radiotherapy for breast cancer using various detection techniques.

scientific article published on July 2002

Evaluation of the in vitro cytotoxicity of some sesquiterpene lactones on a human lung carcinoma cell line using the fast green dye exclusion assay

scientific article published on 01 April 1986

Everolimus Effect on Gastrin and Glucagon in Pancreatic Neuroendocrine Tumors

scientific article published in July 2017

Everolimus Reduces (89)Zr-Bevacizumab Tumor Uptake in Patients with Neuroendocrine Tumors

scientific article published on 01 May 2014

Everolimus for the Treatment of Advanced Pancreatic Neuroendocrine Tumors (pNET): Final Overall Survival (OS) Results of the RADIANT-3 Study.

scientific article published in September 2014

Evolution in sentinel lymph node biopsy in breast cancer

scientific article published on 20 September 2017

Excessively high cell proliferation in sigmoid colon after an oral purge with anthraquinone glycosides

scientific article published on 01 March 1995

Excretion of platinum into breast milk

scientific article published on 01 March 1989

Experimental animal model for anthracycline-induced heart failure.

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Expression of TRAIL and TRAIL death receptors in stage III non-small cell lung cancer tumors

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Extracellular domain shedding influences specific tumor uptake and organ distribution of the EGFR PET tracer 89Zr-imgatuzumab

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Familial cervical cancer: case reports, review and clinical implications.

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Gemcitabine and epirubicin plasma concentration-related excretion in saliva in patients with non-small cell lung cancer.

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Gene expression analysis identifies global gene dosage sensitivity in cancer.

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Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype

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Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy

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Glypican 3 Overexpression across a Broad Spectrum of Tumor Types Discovered with Functional Genomic mRNA Profiling of a Large Cancer Database

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Good results with liver resection for colorectal liver metastases

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Granulosa cell tumors of the ovary: the clinical value of serum inhibin A and B levels in a large single center cohort

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Growth differentiation factor 15 (GDF-15) plasma levels increase during bleomycin- and cisplatin-based treatment of testicular cancer patients and relate to endothelial damage

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HER3, serious partner in crime: therapeutic approaches and potential biomarkers for effect of HER3-targeting

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HIF-1α overexpression in ductal carcinoma in situ of the breast in BRCA1 and BRCA2 mutation carriers

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HLA-Dr-expressing CD8bright cells are only temporarily present in the circulation during subcutaneous recombinant interleukin-2 therapy in renal cell carcinoma patients

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Haptoglobin phenotype is not a predictor of recurrence free survival in high-risk primary breast cancer patients.

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Harnessing Integrative Omics to Facilitate Molecular Imaging of the Human Epidermal Growth Factor Receptor Family for Precision Medicine.

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Heat-shock-protein-27 (hsp27) expression in ovarian carcinoma: relation in response to chemotherapy and prognosis

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Hemodialysis no reason to withhold everolimus.

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Hepatocellular carcinoma in a patient with Gaucher disease on enzyme supplementation therapy

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Heterogeneity in simvastatin-induced cytotoxicity in AML is caused by differences in Ras-isoprenylation.

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High Functional P-glycoprotein Activity is More Often Present in T-cell Acute Lymphoblastic Leukaemic Cells in Adults than in Children ⬇️

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High dose oral amiodarone added to doxorubicin and vindesine for overcoming multidrug resistance in solid tumors.

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High performance liquid chromatographic profiling of tryptophan and related indoles in body fluids and tissues of carcinoid patients

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High-Dose Chemotherapy With Hematopoietic Stem Cell Transplant in Patients With High-Risk Breast Cancer and 4 or More Involved Axillary Lymph Nodes: 20-Year Follow-up of a Phase 3 Randomized Clinical Trial

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High-dosage chemotherapy with autologous bone marrow reinfusion in the treatment of patients with solid tumours. The Groningen experience, 1981-1986

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High-dose chemotherapy with autologous stem-cell support as adjuvant therapy in breast cancer: overview of 15 randomized trials.

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High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer.

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High-dose chemotherapy with peripheral blood progenitor cell transplantation in the adjuvant treatment of breast cancer.

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High-dose cyclophosphamide and high-dose VP 16-213 for recurrent or refractory small cell lung cancer. A phase II study.

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High-dose methotrexate, vincristine and cisplatin as salvage treatment for relapsed non-seminomatous germ-cell cancer

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Higher levels of interleukin-6 in cystic fluids from patients with malignant versus benign ovarian tumors correlate with decreased hemoglobin levels and increased platelet counts

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Hormone receptors as a marker of poor survival in epithelial ovarian cancer

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Human DNA topoisomerase II: biochemistry and role in chemotherapy resistance (review).

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Human Epidermal Growth Factor Receptor 3-Specific Tumor Uptake and Biodistribution of 89Zr-MSB0010853 Visualized by Real-Time and Noninvasive PET Imaging

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Human papilloma virus 16 E6 RNA interference enhances cisplatin and death receptor-mediated apoptosis in human cervical carcinoma cells.

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Human stromal cells are required for an anti-breast cancer effect of zoledronic acid

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Hybrid imaging of fluorescently labeled cancer drugs and label-free four-wave mixing microscopy of cancer cells and tissues.

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Hyperalimentation in autologous bone marrow transplantation for solid tumors. Comparison of total parenteral versus partial parenteral plus enteral nutrition

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Hyperthermic isolated limb perfusion with cisplatin in four patients with sarcomas of soft tissue and bone

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Hyperthermic isolated regional perfusion of the limb with carboplatin

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Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non-polyposis colorectal cancer.

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Ifosfamide given as a 24-h infusion with mesna in patients with recurrent ovarian cancer: preliminary results.

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Images in cardiovascular medicine: myocardial metastases of carcinoid visualized by 18F-dihydroxy-phenyl-alanine positron emission tomography.

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Imaging Diagnostic and Therapeutic Targets: Human Epidermal Growth Factor Receptor 2.

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Imaging of soft-tissue tumors using L-3-[iodine-123]iodo-alpha-methyl-tyrosine single photon emission computed tomography: comparison with proliferative and mitotic activity, cellularity, and vascularity

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Imaging the distribution of an antibody-drug conjugate constituent targeting mesothelin with ⁸⁹Zr and IRDye 800CW in mice bearing human pancreatic tumor xenografts.

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Immuno-PET: a navigator in monoclonal antibody development and applications.

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ImmunoPET and biodistribution with human epidermal growth factor receptor 3 targeting antibody ⁸⁹Zr-RG7116

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ImmunoPET with Anti-Mesothelin Antibody in Patients with Pancreatic and Ovarian Cancer before Anti-Mesothelin Antibody-Drug Conjugate Treatment.

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Immunocytochemical analysis of cisplatin-induced platinum-DNA adducts with double-fluorescence video microscopy ⬇️

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Immunoscintigraphy as potential tool in the clinical evaluation of HER2/neu targeted therapy

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Immunotherapeutic options on the horizon in breast cancer treatment.

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Impact of intracellular chloride concentration on cisplatin accumulation in sensitive and resistant GLC4 cells

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Improved diagnosis of carcinoid tumors by measurement of platelet serotonin

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Improved staging of patients with carcinoid and islet cell tumors with 18F-dihydroxy-phenyl-alanine and 11C-5-hydroxy-tryptophan positron emission tomography.

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Improving gene function predictions using independent transcriptional components

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Improving on Tail-of-the-Curve Evaluation With the American Society of Clinical Oncology Value Framework

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In Vivo Quantification of ERβ Expression by Pharmacokinetic Modeling: Studies with 18F-FHNP PET.

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In vitro chemosensitivity of human lung cancer for vindesine

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In vitro effects of lithium on granulocyte colony formation in normal men, in hematological disorders and in small-cell carcinoma of the lung

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In vitro response of human small-cell lung-cancer cell lines to chemotherapeutic drugs; no correlation with clinical data

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In vivo VEGF imaging with radiolabeled bevacizumab in a human ovarian tumor xenograft.

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In vivo imaging of hepatobiliary transport function mediated by multidrug resistance associated protein and P-glycoprotein.

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In vivo measurement of [11C]verapamil kinetics in human tissues.

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In vivo visualization of MET tumor expression and anticalin biodistribution with the MET-specific anticalin 89Zr-PRS-110 PET tracer.

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Increased cancer risk after liver transplantation: a population-based study

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Increased epithelial cell proliferation in the colon of patients with acromegaly.

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Increased incidence of cardiovascular risk factors in cured testicular cancer patients

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Indispensable benefit of independent investigator-driven research in a changing clinical trial landscape.

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Indium-111-labeled trastuzumab scintigraphy in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer.

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Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1.

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Induction chemotherapy and intensification with autologous bone marrow reinfusion in patients with locally advanced and disseminated breast cancer

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Infection after subcutaneous interleukin-2

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Influence of a highly purified senna extract on colonic epithelium

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Influence of docosahexaenoic acid on cisplatin resistance in a human small cell lung carcinoma cell line.

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Influence of protein properties and protein modification on biodistribution and tumor uptake of anticancer antibodies, antibody derivatives, and non-Ig scaffolds.

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Influence of various beverages on urine acid output.

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Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL

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Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.

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Inhibition of multidrug resistance-associated protein (MRP) activity by rifampicin in human multidrug-resistant lung tumor cells

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Integrating molecular nuclear imaging in clinical research to improve anticancer therapy

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Interlesional Heterogeneity of Metastatic Neuroendocrine Tumors Based on 18F-DOPA PET/CT

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Interleukin-10 and Fas polymorphisms and susceptibility for (pre)neoplastic cervical disease.

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Internet-based support programs to alleviate psychosocial and physical symptoms in cancer patients: a literature analysis

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Interobserver reproducibility of tumor uptake quantification with 89Zr-immuno-PET: a multicenter analysis

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Intraoperative near-infrared fluorescence tumor imaging with vascular endothelial growth factor and human epidermal growth factor receptor 2 targeting antibodies

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Involvement of the TGF-β and β-Catenin Pathways in Pelvic Lymph Node Metastasis in Early-Stage Cervical Cancer

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Irradiation of rat brain reduces P-glycoprotein expression and function.

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Irritability rather than depression during interferon treatment is linked to increased tryptophan catabolism.

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Issues in the chemotherapy of breast cancer

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JM216-, JM118-, and cisplatin-induced cytotoxicity in relation to platinum-DNA adduct formation, glutathione levels and p53 status in human tumour cell lines with different sensitivities to cisplatin.

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Kinetic modeling and efficacy of intraperitoneal paclitaxel combined with intravenous cyclophosphamide and carboplatin as first-line treatment in ovarian cancer

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Knowledge and use of biosimilars in oncology: a survey by the European Society for Medical Oncology

L-3-[123I]Iodo-alpha-methyltyrosine scintigraphy in carcinoid tumors: correlation with biochemical activity and comparison with [111In-DTPA-D-Phe1]-octreotide imaging

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Lack of cross-resistance to fostriecin in a human small-cell lung carcinoma cell line showing topoisomerase II-related drug resistance.

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Lack of nephrotoxicity of new oral platinum drug JM216 in lung cancer patients

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Laparoscopic Placement of PAP Catheters for Intraperitoneal Chemotherapy in Ovarian Carcinoma ⬇️

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Lapatinib and 17AAG reduce 89Zr-trastuzumab-F(ab')2 uptake in SKBR3 tumor xenografts.

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Lesion detection by [89Zr]Zr-DFO-girentuximab and [18F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma

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Lessons from TRAIL-resistance mechanisms in colorectal cancer cells: paving the road to patient-tailored therapy.

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Letter to the Editor: When Expertly Applied, ESMO-MCBS and ASCO Net Health Benefit Scores Usually Agree

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Limitations of the Fast Green Assay for Chemosensitivity Testing in Human Lung Cancer ⬇️

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Limited human epidermal growth factor receptor 2 discordance in metastatic breast cancer patients treated with trastuzumab, a population based study.

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Local antitumour treatment in carcinoma patients with bispecific-monoclonal-antibody-redirected T cells.

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Long-term cardiac follow-up in survivors of a malignant bone tumour

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Long-term disease-free survival after isolated peritoneal metastasis from colonic cancer

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Long-term exposure to circulating platinum is associated with late effects of treatment in testicular cancer survivors.

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Long-term haematological recovery following high-dose chemotherapy with autologous bone marrow transplantation or peripheral stem cell transplantation in patients with solid tumours

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Long-term results of induction- and intensification chemotherapy supported with autologous bone marrow reinfusion in patients with disseminated or T4 breast cancer

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Long-term survival after vinblastine, bleomycin, and cisplatin treatment in patients with germ cell tumors of the ovary: an update

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Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line.

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Low complication rate during intraperitoneal therapy through a totally implanted peritoneal access port in patients with ovarian cancer

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Low p21Waf1/Cip1 protein level sensitizes testicular germ cell tumor cells to Fas-mediated apoptosis.

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Low plasma tryptophan in carcinoid patients is associated with increased urinary cortisol excretion

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Low-dose regimen of interleukin-2 for metastatic renal carcinoma.

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Low-penetrance genes and their involvement in colorectal cancer susceptibility.

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MAPK pathway activity plays a key role in PD-L1 expression of lung adenocarcinoma cells

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MEIS and PBX homeobox proteins in ovarian cancer.

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MLH1 and MSH2 protein expression as a pre-screening marker in hereditary and non-hereditary endometrial hyperplasia and cancer

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Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells.

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Mapatumumab, a fully human agonistic monoclonal antibody that targets TRAIL-R1, in combination with gemcitabine and cisplatin: a phase I study.

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Mapping heterogeneity in glucose uptake in metastatic melanoma using quantitative F-FDG PET/CT analysis

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Mass spectrometric quantification of urinary 6-sulfatoxymelatonin: age-dependent excretion and biological variation

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Measurement of 5-HIAA in urine

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Measurement of tumor VEGF-A levels with 89Zr-bevacizumab PET as an early biomarker for the antiangiogenic effect of everolimus treatment in an ovarian cancer xenograft model

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Mechanism of hyperthermic potentiation of cisplatin action in cisplatin-sensitive and -resistant tumour cells.

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Mechanisms for high methoxymorpholino doxorubicin cytotoxicity in doxorubicin-resistant tumor cell lines.

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Medical oncology in the next century

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Melatonin is not stored in platelets

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Mesna: continuous or bolus infusion?

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Metformin: taking away the candy for cancer?

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Micro-computed tomography (micro-CT) for intraoperative surgical margin assessment of breast cancer: A feasibility study in breast conserving surgery

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Microenvironment involved in FPR1 expression by human glioblastomas

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Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1

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Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation.

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Mitoxantrone: bluebeard for malignancies

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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

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Modest effect of p53, EGFR and HER-2/neu on prognosis in epithelial ovarian cancer: a meta-analysis

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Modification of 5-fluorouracil activity by high-dose methotrexate or leucovorin in advanced colorectal carcinoma

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Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.

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Modulation of cis-diamminedichloroplatinum(II) resistance: a review ⬇️

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Molecular Imaging As a Tool for Drug Development and Trial Design

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Molecular Imaging in Cancer Drug Development

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Molecular Imaging of Radiolabeled Bispecific T-Cell Engager Zr-AMG211 Targeting CEA-Positive Tumors

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Molecular analysis of the topoisomerase II alpha gene and its expression in human ovarian cancer

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Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant

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Molecular imaging as a tool to investigate heterogeneity of advanced HER2-positive breast cancer and to predict patient outcome under trastuzumab emtansine (T-DM1): the ZEPHIR trial.

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Molecular imaging biomarkers for immune checkpoint inhibitor therapy

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Molecular imaging for monitoring treatment response in breast cancer patients.

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Molecular imaging in neuroendocrine tumors: molecular uptake mechanisms and clinical results.

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Molecular imaging in ovarian cancer.

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Molecular imaging of PD-L1 expression and dynamics with the adnectin-based PET tracer 18F-BMS-986192

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Molecular imaging of breast cancer.

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Molecular imaging to enlighten cancer immunotherapies and underlying involved processes

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Molecular imaging: what can be used today.

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Molecular profile of ductal carcinoma in situ of the breast in BRCA1 and BRCA2 germline mutation carriers.

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Molecular prognostic markers in ovarian cancer: toward patient-tailored therapy.

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More on bevacizumab in hereditary hemorrhagic telangiectasia

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Multidrug resistance in oncology and beyond: from imaging of drug efflux pumps to cellular drug targets

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Multidrug resistance related molecules in human and murine lung

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Multiple VEGF family members are simultaneously expressed in ovarian cancer: a proposed model for bevacizumab resistance.

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Mutual interactions between p53 and growth factors in cancer

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Myocardial metastases on 6-[18F] fluoro-L-DOPA PET/CT: a retrospective analysis of 116 serotonin producing neuroendocrine tumour patients.

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NMR spectroscopy analysis of phosphorus metabolites and the effect of adriamycin on these metabolite levels in an adriamycin-sensitive and -resistant human small cell lung carcinoma cell line ⬇️

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Negative inotropic effects of recombinant interleukin 2 in patients without left ventricular dysfunction

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Neuroendocrine tumours and their microenvironment

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Neuropsychiatric symptoms during treatment with interleukin-2

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Neuropsychological investigation into the carcinoid syndrome.

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Niacin (Vitamin B3) Supplementation in Patients with Serotonin-Producing Neuroendocrine Tumor.

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No association between the Arg201Gly polymorphism of the DCC gene and colorectal cancer

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No association between two MLH3 variants (S845G and P844L)and colorectal cancer risk.

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No increased susceptibility to breast cancer from combined CHEK2 1100delC genotype and the HLA class III region risk factors

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No narcosis for bone marrow harvest in autologous bone marrow transplantation.

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Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL.

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Ophthalmic toxicity following paclitaxel infusion

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Options for modulation of drug resistance in ovarian cancer.

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Outcome in patients with differentiated thyroid cancer with negative diagnostic whole-body scanning and detectable stimulated thyroglobulin.

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Outpatient bone marrow harvesting without general anesthesia.

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Ovarian cysts in women receiving tamoxifen for breast cancer

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Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance.

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Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

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P-glycoprotein at the blood-brain barrier and analysis of drug transport with positron-emission tomography.

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P-glycoprotein expression and DNA topoisomerase I and II activity in benign tumors of the ovary and in malignant tumors of the ovary, before and after platinum/cyclophosphamide chemotherapy ⬇️

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PET imaging of estrogen receptors as a diagnostic tool for breast cancer patients presenting with a clinical dilemma

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PET imaging of oestrogen receptors in patients with breast cancer

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PET with the 89Zr-labeled transforming growth factor-β antibody fresolimumab in tumor models

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PET/CT Imaging of 89Zr-N-sucDf-Pembrolizumab in Healthy Cynomolgus Monkeys

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PNU-145156E, a novel angiogenesis inhibitor, in patients with solid tumors: a phase I and pharmacokinetic study

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Paclitaxel and carboplatin concurrent with radiotherapy for primary cervical cancer

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Pancreatic Uptake by 18F-FDOPA PET/CT in Patients With Hypoglycemia After Gastric Bypass Surgery Compared With Controls With or Without Carbidopa Pretreatment

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Pancreatic cyst development: insights from von Hippel-Lindau disease.

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Patients with carcinoid syndrome exhibit symptoms of aggressive impulse dysregulation.

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Persistent low urinary excretion of 5-HIAA is a marker for favourable survival during follow-up in patients with disseminated midgut carcinoid tumours

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Perspectives for tailored chemoprevention and treatment of colorectal cancer in Lynch syndrome.

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Pharmacokinetics of MEN-10755, a novel anthracycline disaccharide analogue, in two phase I studies in adults with advanced solid tumours.

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Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism

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Pharmacokinetics of high-dose teniposide.

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Pharmacokinetics of recombinant human interleukin 3 administered subcutaneously and by continuous intravenous infusion in patients after chemotherapy for ovarian cancer

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Phase I Study of DMOT4039A, an Antibody-Drug Conjugate Targeting Mesothelin, in Patients with Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer.

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Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

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Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer

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Phase I study of MEN-10755, a new anthracycline in patients with solid tumours: a report from the European Organization for Research and Treatment of Cancer, Early Clinical Studies Group.

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Phase I study of saracatinib (AZD0530) in combination with paclitaxel and/or carboplatin in patients with solid tumours

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Phase I study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with 5-fluorouracil and leucovorin: a safe combination.

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Phase I study of transforming growth factor-beta3 mouthwashes for prevention of chemotherapy-induced mucositis.

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Phase I trial with BMS-275183, a novel oral taxane with promising antitumor activity

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Phase I-II study of the addition of alpha-2a interferon to 5-fluorouracil/leucovorin. Pharmacokinetic interaction of alpha-2a interferon and leucovorin.

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Phase II study of a 21-day continuous infusion schedule with epirubicin in metastatic colorectal cancer

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Phase II study of bleomycin, actinomycin D, DTIC and vindesine in disseminated malignant melanoma.

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Phase II study of bleomycin, dacarbazine (DTIC) and vindesine in disseminated malignant melanoma

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Phase II study of intensive chemotherapy with autologous bone marrow transplantation in patients in complete remission of disseminated breast cancer.

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Phase II study of intraperitoneal cisplatin plus systemic etoposide as second-line treatment in patients with small volume residual ovarian cancer.

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Phase II study of subcutaneous interleukin-2 in unselected patients with advanced renal cell cancer on an outpatient basis ⬇️

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Phase one study of twice-weekly vindesine

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Pilot study of vaginal plethysmography in women treated with radiotherapy for gynecological cancer

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Placental growth factor (PlGF)-specific uptake in tumor microenvironment of 89Zr-labeled PlGF antibody RO5323441.

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Plasma fibronectin in idiopathic myelofibrosis

Plasma free metanephrine measurement using automated online solid-phase extraction HPLC tandem mass spectrometry

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Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry.

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Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancer

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Portal and systemic serum growth factor and acute-phase response after laparotomy or partial hepatectomy in patients with colorectal liver metastases: a prognostic role for C-reactive protein and hepatocyte growth factor

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Positron emission tomography of tumour [(18)F]fluoroestradiol uptake in patients with acquired hormone-resistant metastatic breast cancer prior to oestradiol therapy

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Potential Red-Flag Identification of Colorectal Adenomas with Wide-Field Fluorescence Molecular Endoscopy.

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Potential use of recombinant human interleukin-6 in clinical oncology.

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Preclinical characterisation of 111In-DTPA-trastuzumab.

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Preoperative serum squamous cell carcinoma antigen levels in clinical decision making for patients with early-stage cervical cancer.

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Prevention of colorectal cancer: acetylsalicyclic acid and cyclo-oxygenase-2 inhibitors are only partially effective

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Preventive intervention possibilities in radiotherapy- and chemotherapy-induced oral mucositis: results of meta-analyses.

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Pro- and anti-apoptotic effects of p53 in cisplatin-treated human testicular cancer are cell context-dependent.

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Probody therapeutic design of 89Zr-CX-072 promotes accumulation in PD-L1 expressing tumors compared to normal murine lymphoid tissue

scientific article published on 17 January 2020

Procalcitonin behaves as a fast responding acute phase protein in vivo and in vitro

scientific article published on 01 February 2000

Profiling of tryptophan-related plasma indoles in patients with carcinoid tumors by automated, on-line, solid-phase extraction and HPLC with fluorescence detection.

scientific article published in October 2001

Prognosis in childhood and adult acute lymphoblastic leukaemia: a question of maturation?

scientific article published on February 2004

Prognostic significance of tumor necrosis factor-related apoptosis-inducing ligand and its receptors in adjuvantly treated stage III colon cancer patients

scientific article published on 01 November 2006

Prognostic versus predictive value of biomarkers in oncology.

scientific article published on 07 April 2008

Proliferation Rate in Hereditary Nonpolyposis Colon Cancer ⬇️

scientific article published on November 20, 1991

Prospective evaluation of early cardiac damage induced by epirubicin-containing adjuvant chemotherapy and locoregional radiotherapy in breast cancer patients.

scientific article

Prospective study of long-term impact of adjuvant high-dose and conventional-dose chemotherapy on health-related quality of life

scientific article published on December 2007

Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis.

scientific article

Pulmonary function after high-dose chemotherapy with autologous bone marrow transplantation and radiotherapy in patients with advanced loco-regional breast cancer

scientific article published on 01 January 1997

Pulmonary function changes in lung-cancer patients treated with radiation with or without carboplatin

scientific article published on 01 December 1995

Purging of epithelial tumor cells from peripheral blood stem cells by means of the bispecific antibody BIS-1.

scientific article published in June 2000

Quantitation of DNA topoisomerase II alpha messenger ribonucleic acid levels in a small cell lung cancer cell line and two drug resistant sublines using a polymerase chain reaction-aided transcript titration assay.

scientific article published on July 1994

Quantitative Profiling of Platelet-Rich Plasma Indole Markers by Direct-Matrix Derivatization Combined with LC-MS/MS in Patients with Neuroendocrine Tumors

scientific article published on 24 September 2019

Quantitative and qualitative aspects of topoisomerase I and II alpha and beta in untreated and platinum/cyclophosphamide treated malignant ovarian tumors

scientific article published on 01 February 1994

Quantitative fluorescence endoscopy: an innovative endoscopy approach to evaluate neoadjuvant treatment response in locally advanced rectal cancer

scientific article published on 18 September 2019

Quantitative proteomics analysis identifies MUC1 as an effect sensor of EGFR inhibition

scientific article published on 10 October 2018

RAS and BRAF mutations in cell-free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue-tested RAS wild-type advanced colorectal cancer

scientific article published on 30 September 2019

RE: Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration.

scientific article

RECIST - learning from the past to build the future

scientific article published on 20 December 2016

RECIST 1.1 - Standardisation and disease-specific adaptations: Perspectives from the RECIST Working Group

scientific article published on 26 May 2016

RECIST 1.1 for Response Evaluation Apply Not Only to Chemotherapy-Treated Patients But Also to Targeted Cancer Agents: A Pooled Database Analysis

scientific article published on 12 March 2019

RECIST 1.1-Update and clarification: From the RECIST committee.

scientific article published on 14 May 2016

Randomized placebo-controlled trial of granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related febrile neutropenia.

scientific article published on February 1996

Randomized, double-blinded, placebo-controlled intervention study with supplemental calcium in families with hereditary nonpolyposis colorectal cancer

scientific article published on 01 April 1995

Recent developments in diagnosis and treatment of metastatic carcinoid tumours.

scientific article

Recombinant human interleukin 3 in clinical oncology.

scientific article

Recombinant human interleukin 6 in metastatic renal cell cancer: a phase II trial.

scientific article

Recombinant human interleukin-3 to dose-intensify carboplatin and cyclophosphamide chemotherapy in epithelial ovarian cancer: a phase I trial.

scientific article

Recombinant human interleukin-6 induces a rapid and reversible anemia in cancer patients

scientific article published on 01 August 1995

Recombinant human interleukin-6 induces hepatocyte growth factor production in cancer patients

scientific article published on 01 June 2001

Recombinant interferon alpha-2b in patients with metastatic apudomas: effect on tumours and tumour markers ⬇️

scientific article published on November 1, 1992

Rectal and colon cancer: Not just a different anatomic site.

scientific article published on 28 June 2015

Red blood cell glutathione levels in lung cancer patients treated by radiation and continuously infused carboplatin

scientific article published on 01 March 1996

Reduced 5-FU clearance in a patient with low DPD activity due to heterozygosity for a mutant allele of the DPYD gene.

scientific article published on April 2002

Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice

scientific article published on 7 July 2007

Refusing to Become a "Potted Plant"

scientific article published on 01 August 2018

Regulation of TRAIL receptor expression by β-catenin in colorectal tumours

scientific article published on 30 December 2013

Regulation of spontaneous and TNF/IFN-induced IL-6 expression in two human ovarian-carcinoma cell lines.

scientific article published on July 1999

Regulators of homologous recombination repair as novel targets for cancer treatment.

scientific article

Relationship of cellular glutathione to the cytotoxicity and resistance of seven platinum compounds ⬇️

scientific article published on December 15, 1992

Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Breast Cancer.

scientific article published on 13 October 2016

Relevance of high and low penetrance

scientific article published on 01 July 2001

Relevance of high-dose chemotherapy in solid tumours.

scientific article

Renal failure after treatment with interferon alpha 2b

scientific article published on 01 May 2002

Renal toxicity of the anticancer drug fostriecin

scientific article published on 01 January 1998

Replication-defective recombinant Semliki Forest virus encoding GM-CSF as a vector system for rapid and facile generation of autologous human tumor cell vaccines ⬇️

scientific article published on October 1, 2001

Reply to "ESMO-MCBS v1.1: Statistical and Patient Relevant Shortcomings" by R. Emprechtinger et al.

scientific article

Reply to Verlingue, Koscielny and Ferté

scientific article published on 15 September 2014

Reply to the letter to the editor 'Addressing the quality of the ESMO-MCBS' by Del Paggio

scientific article published on 01 August 2017

Reply to the letter to the editor 'Re-aligning the ASCO and ESMO clinical benefit frameworks or modern cancer therapies'.

scientific article

Reply to the letter to the editor 'Utilisation of the ESMO-MCBS in practice of HTA' by Wild et al

scientific article published in November 2016

Reply to the letter to the editor ‘The ESMO Magnitude of Clinical Benefit Scaling Tool: from theory to practice’ by Hartmann and the letter ‘Comment on ESMO Magnitude of Clinical Benefit Scale’ by Muhonen et al

scientific article published on 30 October 2015

Resistance-associated factors in human small-cell lung-carcinoma GLC4 sub-lines with increasing adriamycin resistance.

scientific article published on May 1995

Response assessment criteria for brain metastases: proposal from the RANO group.

scientific article

Review article: anthranoid laxatives and their potential carcinogenic effects.

scientific article

Review of current clinical experience with prolonged (oral) etoposide in cancer treatment.

scientific article published on September 1995

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability.

scientific article published on 5 August 2015

Risk of new primary nonbreast cancers after breast cancer treatment: a Dutch population-based study.

scientific article published in March 2008

Risks and benefits of cisplatin in ovarian cancer. A quality-adjusted survival analysis

scientific article published on 01 March 1990

Role of chemokines and their receptors in cancer.

scientific article published on January 2009

Role of metallothionein in cisplatin sensitivity of germ-cell tumours

scientific article published on 01 March 2000

Role of the glutathione S-conjugate pump in cisplatin resistance

scientific article published on 01 April 1995

Routine bone scintigraphy in primary staging of soft tissue sarcoma; Is it worthwhile?

scientific article published on 01 October 2000

Screening for infectious foci in breast cancer patients prior to high-dose chemotherapy and stem cell transplantation.

scientific article

Selective expression of cholesterol metabolism genes in normal CD34+CD38- cells with a heterogeneous expression pattern in AML cells.

scientific article published on May 2006

Sensitivity to Fas-mediated apoptosis in high-risk HPV-positive human cervical cancer cells: relationship with Fas, caspase-8, and Bid.

scientific article

Sensitization to cisplatin action by step-down heating in cDDP-sensitive and -resistant cells.

scientific article published in May 1995

Serial FLT PET imaging to discriminate between true progression and pseudoprogression in patients with newly diagnosed glioblastoma: a long-term follow-up study

scientific article published on 21 July 2018

Serotonin and Dopamine Receptor Expression in Solid Tumours Including Rare Cancers

scientific article published on 02 September 2019

Serotonin metabolism following platinum-based chemotherapy combined with the serotonin type-3 antagonist tropisetron

scientific article published on 01 January 1995

Serotonin, catecholamines, histamine, and their metabolites in urine, platelets, and tumor tissue of patients with carcinoid tumors

scientific article published on 01 January 1994

Serum obtained from rats after partial hepatectomy enhances growth of cultured colon carcinoma cells

scientific article published on 01 January 1998

Serum response of hepatocyte growth factor, insulin-like growth factor-I, interleukin-6, and acute phase proteins in patients with colorectal liver metastases treated with partial hepatectomy or cryosurgery

scientific article published on 01 March 2001

Serum squamous cell carcinoma antigen and CYFRA 21-1 in cervical cancer treatment

scientific article published in January 2002

Sexual function in patients with metastatic midgut carcinoid tumours.

scientific article published on 26 November 2008

Short-term continuous infusion of mitozantrone for advanced breast cancer

scientific article published on 01 April 1990

Shortages of inexpensive essential medicines

scientific article published on 18 April 2019

Side effects of therapy: case 2. Tamoxifen and uterine abnormalities.

scientific article

Small cell lung cancer and the influence of chemotherapy on CFUcs in bone marrow ⬇️

scientific article published on February 1, 1984

Soluble TRAIL concentrations are raised in patients with systemic lupus erythematosus.

scientific article published on 25 November 2004

Stability of the new anticancer platinum analogue 1,2-diaminomethyl-cyclobutane-platinum(II)-lactate (lobaplatin; D19466) in intravenous solutions.

scientific article published in June 1992

Structural alterations of transforming growth factor-beta receptor genes in human cervical carcinoma

scientific article published on 01 July 1999

Successful long-term control of idiopathic hypereosinophilic syndrome with etoposide.

scientific article

Successful treatment of metastatic esthesioneuroblastoma

scientific article published on 01 December 2003

Sulfonylurea derivatives and cancer, friend or foe?

scientific article published on 10 August 2019

Surgery by consultant gynecologic oncologists improves survival in patients with ovarian carcinoma

scientific article published on 01 February 2006

Survival-related profile, pathways, and transcription factors in ovarian cancer

scientific article published on February 2009

Synthesis and Evaluation of the Estrogen Receptor β-Selective Radioligand 2-18F-Fluoro-6-(6-Hydroxynaphthalen-2-yl)Pyridin-3-ol: Comparison with 16α-18F-Fluoro-17β-Estradiol

scientific article published in December 2016

Systolic and diastolic dysfunction in long-term adult survivors of childhood cancer.

scientific article published on 21 June 2011

TGF-β Antibody Uptake in Recurrent High-Grade Glioma Imaged with 89Zr-Fresolimumab PET.

scientific article

TNF-related apoptosis-inducing ligand cooperates with NSAIDs via activated Wnt signalling in (pre)malignant colon cells.

scientific article published on 29 October 2010

TRAIL induces apoptosis in human colorectal adenoma cell lines and human colorectal adenomas.

scientific article published on July 2006

TRAIL receptor targeting therapies for non-small cell lung cancer: current status and perspectives.

scientific article published on 29 December 2009

Tailored imaging of islet cell tumors of the pancreas amidst increasing options.

scientific article published on 25 June 2011

Tamoxifen and endometrial screening

scientific article published on 01 January 2000

Tamoxifen effects on subjective and psychosexual well-being, in a randomised breast cancer study comparing high-dose and standard-dose chemotherapy.

scientific article published on May 2002

Tamoxifen; wider indications, more frequent controls?

scientific article published in September 2001

Targeting FLIP and Mcl-1 using a combination of aspirin and sorafenib sensitizes colon cancer cells to TRAIL.

scientific article

Targeting TRAIL death receptors.

scientific article published on 28 July 2008

Targeting TRAIL towards the clinic.

scientific article published on December 2011

Targeting breast cancer through its microenvironment: current status of preclinical and clinical research in finding relevant targets

scientific article

Targeting pro-apoptotic trail receptors sensitizes HeLa cervical cancer cells to irradiation-induced apoptosis

scientific article published on October 2008

Telomerase activity as a biomarker for (pre)neoplastic cervical disease in scrapings and frozen sections from patients with abnormal cervical smear.

scientific article published in June 1998

Telomerase in (pre)neoplastic cervical disease

scientific article published on 01 October 2000

Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer

scientific article published on 01 March 2001

Telomerase in relation to expression of p53, c-Myc and estrogen receptor in ovarian tumours ⬇️

scientific article published on November 1, 2003

Telomerase targeting in cancer treatment: new developments

scientific article published on 01 April 1999

The HLA class III subregion is responsible for an increased breast cancer risk

scientific article published on 22 July 2003

The Human Leukocyte Antigen Region and Colorectal Cancer Risk

article

The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification ⬇️

scientific article published on October 1, 1995

The analysis of longitudinal quality of life measures with informative drop-out: a pattern mixture approach

scientific article

The antibody-drug conjugate target landscape across a broad range of tumour types.

scientific article

The attractive Achilles heel of germ cell tumours: an inherent sensitivity to apoptosis-inducing stimuli.

scientific article

The carcinoid syndrome and angioedema

scientific article published on 01 October 1995

The clinical trail of TRAIL.

scientific article published on August 2006

The clinical value of squamous cell carcinoma antigen in cancer of the uterine cervix

scientific article published on 01 January 1998

The components of progression as explanatory variables for overall survival in the Response Evaluation Criteria in Solid Tumours 1.1 database.

scientific article published on 10 April 2014

The current and future role of the medical oncologist in the professional care for cancer patients: a position paper by the European Society for Medical Oncology (ESMO).

scientific article published on 13 December 2013

The distribution of drug-efflux pumps, P-gp, BCRP, MRP1 and MRP2, in the normal blood-testis barrier and in primary testicular tumours.

scientific article

The effect of partial hepatectomy on tumor growth in rats: in vivo and in vitro studies

scientific article published on 01 October 1995

The effects of tamoxifen on the female genital tract

scientific article published in November 2003

The extrinsic apoptosis pathway and its prognostic impact in ovarian cancer

scientific article published on 3 December 2009

The impact of adjuvant therapy on contralateral breast cancer risk and the prognostic significance of contralateral breast cancer: a population based study in the Netherlands.

scientific article published on 9 August 2007

The importance of family history in young patients with endometrial cancer.

scientific article

The influence of endocrine treatments for breast cancer on health-related quality of life.

scientific article published on 02 June 2008

The modulatory impact of recombinant human interleukin-6 on the immune system of cancer patients

scientific article published on 01 July 1999

The myc family of oncogenes and their presence and importance in small-cell lung carcinoma and other tumour types.

scientific article

The ovary: cysts, screening, and tamoxifen

scientific article published on 01 June 2000

The prognostic effect of the number of histologically examined axillary lymph nodes in breast cancer: stage migration or age association?

scientific article published on 20 February 2006

The prognostic value of TRAIL and its death receptors in cervical cancer

scientific article published in September 2009

The relation between soluble apoptotic proteins and subclinical cardiotoxicity in adjuvant-treated breast cancer patients

scientific article published on 01 September 2006

The role of ATM and 53BP1 as predictive markers in cervical cancer.

scientific article

The role of apoptosis-related genes in non-small-cell lung cancer.

scientific article

The role of breast cancer resistance protein in acute lymphoblastic leukemia.

scientific article published in November 2003

The role of drug efflux pumps in acute myeloid leukemia.

scientific article

The role of response evaluation criteria in solid tumour in anticancer treatment evaluation: results of a survey in the oncology community.

scientific article

Theranostics Using Antibodies and Antibody-Related Therapeutics.

scientific article published on September 2017

Third-party payers and breast cancer study.

scientific article published in February 1998

Threshold Analysis and Biodistribution of Fluorescently Labeled Bevacizumab in Human Breast Cancer

scientific article published on 22 November 2016

Tissue distribution of the death ligand TRAIL and its receptors.

scientific article published in June 2004

Total 18F-dopa PET tumour uptake reflects metabolic endocrine tumour activity in patients with a carcinoid tumour.

scientific article

Total abdominal 18F-FDG uptake reflects intestinal adenoma burden in Apc mutant mice.

scientific article published on 14 February 2011

Toward molecular imaging-driven drug development in oncology

scientific article published on 01 June 2011

Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis.

scientific article published in December 2003

Towards optimal personalized diet and vitamin supplementation in NET patients.

scientific article published in March 2018

Toxicity Adjustment in the ESMO-MCBS: A diligent process of data interpretation with peer review that is far from "Gestalt".

scientific article

Toxicity and efficacy of escalating dosages of recombinant human interleukin-6 after chemotherapy in patients with breast cancer or non-small-cell lung cancer ⬇️

scientific article published on October 1, 1995

Toxicity of hyperthermic isolated limb perfusion with cisplatin for recurrent melanoma of the lower extremity after previous perfusion treatment

scientific article published on 01 August 1993

Transcriptional effects of copy number alterations in a large set of human cancers

scientific article published on 05 February 2020

Transforming growth factor (TGF)-β expression and activation mechanisms as potential targets for anti-tumor therapy and tumor imaging.

scientific article published on 12 May 2012

Translating TRAIL-receptor targeting agents to the clinic.

scientific article published on 21 April 2012

Translation of New Molecular Imaging Approaches to the Clinical Setting: Bridging the Gap to Implementation.

scientific article published on February 2016

Transport of glutathione conjugates into secretory vesicles is mediated by the multidrug-resistance protein 1.

scientific article

Trastuzumab duocarmazine in locally advanced and metastatic solid tumours and HER2-expressing breast cancer: a phase 1 dose-escalation and dose-expansion study

scientific article published on 27 June 2019

Trastuzumab pharmacokinetics influenced by extent human epidermal growth factor receptor 2-positive tumor load.

scientific article published on 10 May 2010

Treatment costs and quality of life with granulocyte-macrophage colony-stimulating factor in patients with antineoplastic therapy-related febrile neutropenia. Results of a randomised placebo-controlled trial.

scientific article published on September 1997

Treatment of special breast cancer patients ⬇️

scientific article published on September 1, 1998

Treatment with high-dose simvastatin inhibits geranylgeranylation in AML blast cells in a subset of AML patients.

scientific article published on 25 November 2011

Troponin I, troponin T, and creatine kinase-MB mass in patients with the carcinoid syndrome with and without heart failure

scientific article published on 01 December 1999

Tube feeding of cancer patients treated with chemotherapy

scientific article published on 01 January 1985

Tumor necrosis factor-related apoptosis-inducing ligand pathway and its therapeutic implications

scientific article published on 01 April 2006

Tumor progression in a giant cell type malignant fibrous histiocytoma of bone: clinical, radiologic, histologic, and cytogenetic evidence

scientific article published on 01 May 1994

Tumor-Specific Uptake of Fluorescent Bevacizumab-IRDye800CW Microdosing in Patients with Primary Breast Cancer: A Phase I Feasibility Study

scientific article published on 9 November 2016

Tumor-associated macrophages in breast cancer: Innocent bystander or important player?

scientific article published on 28 August 2018

Turning promise into progress for antiangiogenic agents in epithelial ovarian cancer

scientific article published on 21 April 2012

Uptake mechanisms of L-3-[125I]iodo-alpha-methyl-tyrosine in a human small-cell lung cancer cell line: comparison with L-1.

scientific article

Use of Video-consultation is Feasible During Follow-up Care of Patients with a Neuroendocrine Tumour

scientific article published on 03 March 2018

Use of natriuretic peptides for detecting cardiac dysfunction in long-term disease-free breast cancer survivors.

scientific article published in September 2005

Use of selective serotonin reuptake inhibitors is associated with very low plasma-free serotonin concentrations in humans

scientific article published on 10 October 2019

VEGF pathway targeting agents, vessel normalization and tumor drug uptake: from bench to bedside

scientific article

VEGF-SPECT with ¹¹¹In-bevacizumab in stage III/IV melanoma patients.

scientific article

Value of P-glycoprotein, glutathione S-transferase pi, c-erbB-2, and p53 as prognostic factors in ovarian carcinomas

scientific article published on 01 January 1995

Vemurafenib-Induced Disseminated Intravascular Coagulation in Metastatic Melanoma.

scientific article published on 28 April 2014

Venlafaxine versus clonidine for the treatment of hot flashes in breast cancer patients: a double-blind, randomized cross-over study

scientific article published in August 2008

Video-rate optical flow corrected intraoperative functional fluorescence imaging

scientific article

Visual and quantitative evaluation of [18F]FES and [18F]FDHT PET in patients with metastatic breast cancer: an interobserver variability study

scientific article published on 19 April 2020

Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer.

scientific article

Web-based personalised information and support for patients with a neuroendocrine tumour: randomised controlled trial

scientific article published on 28 February 2019

Web-based tailored psycho-education for breast cancer patients at the onset of the survivorship phase: a multicenter randomized controlled trial

scientific article

When is off-label off-road?

scientific article published on 01 October 2019

Which patients are prone to undergo disproportionate recurrent CT imaging and should we worry?

scientific article published on 13 February 2020

Whole-body PET imaging of breast cancer characteristics to improve precision treatment

scientific article published in May 2014

Words matter: distinguishing "personalized medicine" and "biologically personalized therapeutics"

scientific article

Zeniplatin in patients with advanced ovarian cancer, a phase II study with a third generation platinum complex.

scientific article published on January 1993

Zirconium-89-trastuzumab positron emission tomography as a tool to solve a clinical dilemma in a patient with breast cancer.

scientific article

[Dutch Institute for Healthcare Improvement guideline, "Treatment of breast carcinoma": important document but an open attitude to new "evidence" is necessary]

scientific article published on 01 November 2002

[Expression and prognostic value of the drug resistance markers P-gp, Mrp1, Mrp2, and Lrp in ovarian carcinoma].

scientific article

[High-dose chemotherapy with stem cell support for solid tumors in adults]

scientific article published on 01 April 1999

[One hundred years of the Association of Surgeons in the Netherlands. VIII. Surgical oncology]

scientific article published on 01 October 2002

[Primary surgery by a gynecological oncologist improves the prognosis in patients with ovarian carcinoma]

scientific article published on 01 January 2009

[Targeted therapy: the benefit of new oncological tests]

scientific article published on 01 January 2011

[The limitations of observational research]

scientific article published on 01 January 2009

[The role of trastuzumab in mammary carcinoma in The Netherlands]

scientific article published on 01 April 2006

[Treatment of patients with differentiated thyroid carcinoma]

scientific article published on 01 June 2002

cis-diamminedichloroplatinum(ii) resistance in vitro and in vivo in human embryonal carcinoma cells.

scientific article published on December 1993

iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics

scientific article published on 2 March 2017

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