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List of works by Emily Edwards

Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation, function and EBV immunity.

scientific article

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells

scientific article published on 06 February 2019

Beyond monogenetic rare variants: tackling the low rate of genetic diagnoses in predominantly antibody deficiency

scientific article published on 17 August 2020

Combined immunodeficiency and Epstein-Barr virus-induced B cell malignancy in humans with inherited CD70 deficiency

scientific article published on 23 December 2016

Design, synthesis and evaluation of β-lactam antigenic peptide hybrids; unusual opening of the β-lactam ring in acidic media ⬇️

scientific article published on October 7, 2010

Human immunity against EBV-lessons from the clinic.

scientific article published on 20 January 2017

Influenza-specific IgG1+ memory B-cell numbers increase upon booster vaccination in healthy adults but not in patients with predominantly antibody deficiency

scientific article published on 16 October 2020

MHC class I molecules with Superenhanced CD8 binding properties bypass the requirement for cognate TCR recognition and nonspecifically activate CTLs.

scientific article published on 26 February 2010

Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition

scientific article

Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.

scientific article published on 12 March 2018

Phenotypic and transcriptional profile correlates with functional plasticity of antigen-specific CD4+ T cells.

scientific article published on 3 December 2013

Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers

scientific article

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