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List of works by Trevor G Smart

-Aminobutyric Acid Type B (GABAB) Receptor Internalization Is Regulated by the R2 Subunit ⬇️

scientific article published on July 8, 2011

A Selective Nociceptin Receptor Antagonist to Treat Depression: Evidence from Preclinical and Clinical Studies

scientific article

A translational study of the effects of ketamine and pregabalin on temporal summation of experimental pain

scientific article published in November 2011

Activation of single heteromeric GABA(A) receptor ion channels by full and partial agonists ⬇️

scientific article

An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis

scientific article published on June 21, 2012

Brief report: isogenic induced pluripotent stem cell lines from an adult with mosaic down syndrome model accelerated neuronal ageing and neurodegeneration

scientific article published on June 2015

CaMKII phosphorylation of the GABA(A) receptor: receptor subtype- and synapse-specific modulation

scientific article published on 30 March 2009

Cell surface expression of homomeric GABAA receptors depends on single residues in subunit transmembrane domains

scientific article published on 09 July 2018

Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites.

scientific article

Deficits in spatial memory correlate with modified {gamma}-aminobutyric acid type A receptor tyrosine phosphorylation in the hippocampus.

scientific article

Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants

scientific article

Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties

scientific article published on 6 March 2018

Disrupting the clustering of GABAA receptor α2 subunits in the frontal cortex leads to reduced γ-power and cognitive deficits

scientific article published on 16 September 2013

Effects of gabapentin on experimental somatic pain and temporal summation

scientific article published in September 2007

Efficient assessment of efficacy in post-traumatic peripheral neuropathic pain patients: pregabalin in a randomized, placebo-controlled, crossover study ⬇️

scientific article published on July 27, 2012

Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

scientific article

Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission

scientific article

HEK293 cell line: a vehicle for the expression of recombinant proteins

scientific article

Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking

scholarly article

Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells

scientific article published on 16 July 2015

Intracellular chloride ions regulate the time course of GABA-mediated inhibitory synaptic transmission

scientific article published in August 2009

Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia

scientific article (publication date: 4 July 2003)

Mechanisms of inhibition and activation of extrasynaptic αβ GABA<sub>A</sub> receptors

scientific article published on 09 February 2022

Methods for recording and measuring tonic GABAA receptor-mediated inhibition

scientific article

Modulation of neurosteroid potentiation by protein kinases at synaptic- and extrasynaptic-type GABAA receptors

scientific article

Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors

scientific journal article

Murine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.

scientific article

Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition

scientific article

Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease

scientific article

Nanoscale live-cell imaging using hopping probe ion conductance microscopy

scientific article published on March 2009

Neurosteroid binding sites on GABA(A) receptors

scientific article published on 21 April 2007

Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes

scientific article

Photo-antagonism of the GABAA receptor.

scientific article

Physiological role for GABA<sub>A</sub> receptor desensitization in the induction of long-term potentiation at inhibitory synapses

scientific article published on 09 April 2021

Probing GABAA receptors with inhibitory neurosteroids

scientific article published on 12 February 2018

Prolonged activation of NMDA receptors promotes dephosphorylation and alters postendocytic sorting of GABAB receptors

scientific article

Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus

scientific article

Proton modulation of recombinant GABA(A) receptors: influence of GABA concentration and the beta subunit TM2-TM3 domain

scientific article

Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory.

scientific article published on 20 April 2015

Structural determinants and regulation of spontaneous activity in GABA<sub>A</sub> receptors

scientific article published on 15 September 2021

Sushi domains confer distinct trafficking profiles on GABAB receptors

scientific article

The GDP-GTP exchange factor collybistin: an essential determinant of neuronal gephyrin clustering

scientific article

The future of pharmacology

scientific article

The major central endocannabinoid directly acts at GABA A receptors ⬇️

scientific article published on October 24, 2011

Tyrosine phosphorylation of GABAA receptor γ2-subunit regulates tonic and phasic inhibition in the thalamus.

scientific article

Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition

scientific article published on 06 October 2009

Zinc-mediated inhibition of GABA(A) receptors: discrete binding sites underlie subtype specificity

scientific article

Zn2+ ions: modulators of excitatory and inhibitory synaptic activity.

scientific article published in October 2004

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