List of works - Boris Chernyak

"Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis.

scientific article

6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes

scientific article published on 01 January 1997

A cytochrome c mutant with high electron transfer and antioxidant activities but devoid of apoptogenic effect

scientific article published on March 2002

A short-chain alkyl derivative of Rhodamine 19 acts as a mild uncoupler of mitochondria and a neuroprotector

scientific article published on 16 July 2014

Activation of a complex of ATPase with the natural protein inhibitor in submitochondrial particles

scientific article published on 01 October 1990

Adenine nucleotide-binding sites on mitochondrial F1-ATPase: studies of the inactive complex formed upon binding ADP at a catalytic site

scientific article published on June 1, 1992

Adenylylimidodiphosphate release from the active site of submitochondrial particles ATPase ⬇️

scientific article published on August 15, 1979

An attempt to prevent senescence: a mitochondrial approach.

scientific article published on 29 December 2008

Analysis of genes regulated by DUX4 via oxidative stress reveals potential therapeutic targets for treatment of facioscapulohumeral dystrophy

publication published on 13 May 2021

Ca(2+)-triggered membrane permeability transition in deenergized mitochondria from rat liver

scientific article published on 01 May 1995

Comparative analysis of proapoptotic activity of cytochrome c mutants in living cells.

scientific article published on August 2005

Control of DNA integrity in skeletal muscle under physiological and pathological conditions

scientific article published on 25 April 2017

Cyclosporin A-sensitive release of Ca2+ from mitochondria in intact thymocytes

scientific article published on 01 November 1997

Cytoskeleton inhibitors combined with TRAIL induce apoptosis in HeLa carcinoma cells overexpressing antiapoptotic protein Bcl-2.

scientific article published in March 2008

DUX4 Pathological Expression: Causes and Consequences in Cancer

scientific article published on 16 April 2019

Depletion of mitochondrial reactive oxygen species downregulates epithelial-to-mesenchymal transition in cervical cancer cells

scientific article published on 25 November 2016

Derivatives of the cationic plant alkaloids berberine and palmatine amplify protonophorous activity of fatty acids in model membranes and mitochondria

scientific article published on 29 September 2012

Does Oxidation of Mitochondrial Cardiolipin Trigger a Chain of Antiapoptotic Reactions?

scientific article published on 01 October 2018

Effect of oxidative stress on dynamics of mitochondrial reticulum.

scientific article published on 15 May 2006

Effects of Zn2+ on the activity and binding of the mitochondrial ATPase inhibitor protein, IF1

scientific article published on 01 June 1993

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production.

scientific article

High-pressure enzyme kinetics. Lactate dehydrogenase in an optical cell that allows a reaction to be started under high pressure

scientific article published on 01 April 1984

In search of novel highly active mitochondria-targeted antioxidants: thymoquinone and its cationic derivatives.

scientific article published on 10 May 2013

Induction of autophagy by depolarization of mitochondria.

scientific article published on 20 February 2018

Induction of the non-selective mitochondrial pore in lymphoid cells. 1. Permeabilized rat thymocytes

scientific article published on 01 August 1999

Induction of the non-selective mitochondrial pore in lymphoid cells. 2. Intact rat thymocytes

scientific article published on 01 August 1999

Long-distance apoptotic killing of cells is mediated by hydrogen peroxide in a mitochondrial ROS-dependent fashion.

scientific article published in November 2005

Low Concentrations of Uncouplers of Oxidative Phosphorylation Prevent Inflammatory Activation of Endothelial Cells by Tumor Necrosis Factor

scientific article published on May 2015

MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation

scientific article published on 13 November 2019

Mitochondria-Targeted Antioxidant SkQ1 (10-(6´-Plastoquinonyl)decyltriphenylphosphonium Bromide) Inhibits Mast Cell Degranulation in vivo and in vitro.

scientific article published in December 2017

Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

scientific article

Mitochondria-Targeted Antioxidant SkQR1 Reduces TNF-Induced Endothelial Permeability in vitro.

scientific article published on October 2016

Mitochondria-Targeted Antioxidants and Uncouplers of Oxidative Phosphorylation in Treatment of the Systemic Inflammatory Response Syndrome (SIRS).

scientific article

Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice.

scientific article published on 30 June 2015

Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

scientific article published on 31 July 2018

Mitochondria-targeted antioxidants as a prospective therapeutic strategy for multiple sclerosis.

scientific article published on 16 March 2017

Mitochondria-targeted antioxidants prevent TNFα-induced endothelial cell damage.

scientific article published on February 2014

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.

scientific article

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells.

scientific article

Mitochondrial reactive oxygen species are involved in chemoattractant-induced oxidative burst and degranulation of human neutrophils in vitro.

scientific article

Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies.

scientific article published on June 2011

Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo

scientific article published on 10 February 2020

Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell.

scientific article published on 8 April 2008

Novel mitochondria-targeted antioxidants, “Skulachev-Ion” derivatives, accelerate dermal wound healing in animals

scientific article published on 01 March 2010

Novel mitochondria-targeted antioxidants: plastoquinone conjugated with cationic plant alkaloids berberine and palmatine

scientific article published on 14 June 2011

Novel penetrating cations for targeting mitochondria.

scientific article published on January 2013

Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis.

scientific article

Proapoptotic activity of cytochrome c in living cells: effect of K72 substitutions and species differences.

scientific article published on 19 April 2008

Prolonged lipid oxidation after photodynamic treatment. Study with oxidation-sensitive probe C11-BODIPY581/591.

scientific article published on 26 January 2005

Prooxidant properties of p66shc are mediated by mitochondria in human cells

scientific article

Protective effects of mitochondria-targeted antioxidant SkQ in aqueous and lipid membrane environments.

scientific article published in April 2008

Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway.

scientific article

Radioprotective effects of mitochondria-targeted antioxidant SkQR1.

scientific article published on 12 December 2014

Reactive oxygen species produced in mitochondria are involved in age-dependent changes of hematopoietic and mesenchymal progenitor cells in mice. A study with the novel mitochondria-targeted antioxidant SkQ1

scientific article published on 17 June 2010

Regulation of ATP hydrolysis in hepatoma 22a mitochondria ⬇️

scientific article published on May 1, 1991

Regulation of ATP hydrolysis in liver mitochondria from ground squirrel

scientific article published on 01 June 1990

Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells.

scientific article published in February 2002

Role of Reactive Oxygen Species in Mast Cell Degranulation.

scientific article published on December 2016

Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium.

scientific article

Scavenging of reactive oxygen species in mitochondria induces myofibroblast differentiation.

scientific article published in November 2010

Selective elimination of mitochondria from living cells induced by inhibitors of bioenergetic functions.

scientific article

Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane

scientific article published on 01 April 1995

SkBQ - prooxidant addressed to mitochondria.

scientific article published on December 2013

The Mitochondrial Permeability Transition Pore is Modulated by Oxidative Agents Through Both Pyridine Nucleotides and Glutathione at Two Separate Sites

scientific article published on 01 June 1996

The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III.

scientific article published on January 2014

The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface

scientific article published on 18 December 2018

The interaction of MgADP with H+ -ATPase in rat liver mitochondria

scientific article published on 01 March 1988

The oxidation of sulfhydryl groups in mitochondrial F1-ATPase decreases the rate of its inactivation by the natural protein inhibitor

scientific article published on 01 August 1985

The role of mitochondrial ROS in antibacterial immunity.

scientific article

Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis

scientific article published on 01 July 2019

Thread-grain transition of mitochondrial reticulum as a step of mitoptosis and apoptosis.

scientific article published in January 2004

Uncoupling of respiration and oxidative phosphorylation in transformed mouse L929 fibroblasts induced by cocultivation with human erythroleukemic K562 cells or by tumor necrosis factor.

scientific article published in September 2001

Zn2+ allows differentiation between two kinds of IF1-ATPase interaction in intact mitochondria

scientific article published on 01 November 1992

List of works by Boris Chernyak

"Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis.

6-Ketocholestanol is a recoupler for mitochondria, chromatophores and cytochrome oxidase proteoliposomes

A cytochrome c mutant with high electron transfer and antioxidant activities but devoid of apoptogenic effect

A short-chain alkyl derivative of Rhodamine 19 acts as a mild uncoupler of mitochondria and a neuroprotector

Activation of a complex of ATPase with the natural protein inhibitor in submitochondrial particles

Adenine nucleotide-binding sites on mitochondrial F1-ATPase: studies of the inactive complex formed upon binding ADP at a catalytic site

Adenylylimidodiphosphate release from the active site of submitochondrial particles ATPase ⬇️

An attempt to prevent senescence: a mitochondrial approach.

Analysis of genes regulated by DUX4 via oxidative stress reveals potential therapeutic targets for treatment of facioscapulohumeral dystrophy

Ca(2+)-triggered membrane permeability transition in deenergized mitochondria from rat liver

Comparative analysis of proapoptotic activity of cytochrome c mutants in living cells.

Control of DNA integrity in skeletal muscle under physiological and pathological conditions

Cyclosporin A-sensitive release of Ca2+ from mitochondria in intact thymocytes

Cytoskeleton inhibitors combined with TRAIL induce apoptosis in HeLa carcinoma cells overexpressing antiapoptotic protein Bcl-2.

DUX4 Pathological Expression: Causes and Consequences in Cancer

Depletion of mitochondrial reactive oxygen species downregulates epithelial-to-mesenchymal transition in cervical cancer cells

Derivatives of the cationic plant alkaloids berberine and palmatine amplify protonophorous activity of fatty acids in model membranes and mitochondria

Does Oxidation of Mitochondrial Cardiolipin Trigger a Chain of Antiapoptotic Reactions?

Effect of oxidative stress on dynamics of mitochondrial reticulum.

Effects of Zn2+ on the activity and binding of the mitochondrial ATPase inhibitor protein, IF1

HIV-1 Tat protein induces DNA damage in human peripheral blood B-lymphocytes via mitochondrial ROS production.

High-pressure enzyme kinetics. Lactate dehydrogenase in an optical cell that allows a reaction to be started under high pressure

In search of novel highly active mitochondria-targeted antioxidants: thymoquinone and its cationic derivatives.

Induction of autophagy by depolarization of mitochondria.

Induction of the non-selective mitochondrial pore in lymphoid cells. 1. Permeabilized rat thymocytes

Induction of the non-selective mitochondrial pore in lymphoid cells. 2. Intact rat thymocytes

Long-distance apoptotic killing of cells is mediated by hydrogen peroxide in a mitochondrial ROS-dependent fashion.

Low Concentrations of Uncouplers of Oxidative Phosphorylation Prevent Inflammatory Activation of Endothelial Cells by Tumor Necrosis Factor

MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation

Mitochondria-Targeted Antioxidant SkQ1 (10-(6´-Plastoquinonyl)decyltriphenylphosphonium Bromide) Inhibits Mast Cell Degranulation in vivo and in vitro.

Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice

Mitochondria-Targeted Antioxidant SkQR1 Reduces TNF-Induced Endothelial Permeability in vitro.

Mitochondria-Targeted Antioxidants and Uncouplers of Oxidative Phosphorylation in Treatment of the Systemic Inflammatory Response Syndrome (SIRS).

Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice.

Mitochondria-targeted antioxidant SkQ1 suppresses fibrosarcoma and rhabdomyosarcoma tumour cell growth

Mitochondria-targeted antioxidants as a prospective therapeutic strategy for multiple sclerosis.

Mitochondria-targeted antioxidants prevent TNFα-induced endothelial cell damage.

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: synthesis and in vitro studies.

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells.

Mitochondrial reactive oxygen species are involved in chemoattractant-induced oxidative burst and degranulation of human neutrophils in vitro.

Mitochondrial-targeted plastoquinone derivatives. Effect on senescence and acute age-related pathologies.

Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo

Novel mechanism of elimination of malfunctioning mitochondria (mitoptosis): formation of mitoptotic bodies and extrusion of mitochondrial material from the cell.

Novel mitochondria-targeted antioxidants, “Skulachev-Ion” derivatives, accelerate dermal wound healing in animals

Novel mitochondria-targeted antioxidants: plastoquinone conjugated with cationic plant alkaloids berberine and palmatine

Novel penetrating cations for targeting mitochondria.

Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis.

Proapoptotic activity of cytochrome c in living cells: effect of K72 substitutions and species differences.

Prolonged lipid oxidation after photodynamic treatment. Study with oxidation-sensitive probe C11-BODIPY581/591.

Prooxidant properties of p66shc are mediated by mitochondria in human cells

Protective effects of mitochondria-targeted antioxidant SkQ in aqueous and lipid membrane environments.

Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway.

Radioprotective effects of mitochondria-targeted antioxidant SkQR1.

Reactive oxygen species produced in mitochondria are involved in age-dependent changes of hematopoietic and mesenchymal progenitor cells in mice. A study with the novel mitochondria-targeted antioxidant SkQ1

Regulation of ATP hydrolysis in hepatoma 22a mitochondria ⬇️

Regulation of ATP hydrolysis in liver mitochondria from ground squirrel

Respiration and mitochondrial membrane potential are not required for apoptosis and anti-apoptotic action of Bcl-2 in HeLa cells.

Role of Reactive Oxygen Species in Mast Cell Degranulation.

Role of mitochondrial reactive oxygen species in age-related inflammatory activation of endothelium.

Scavenging of reactive oxygen species in mitochondria induces myofibroblast differentiation.

Selective elimination of mitochondria from living cells induced by inhibitors of bioenergetic functions.

Selective inhibition of the mitochondrial permeability transition pore at the oxidation-reduction sensitive dithiol by monobromobimane

SkBQ - prooxidant addressed to mitochondria.

The Mitochondrial Permeability Transition Pore is Modulated by Oxidative Agents Through Both Pyridine Nucleotides and Glutathione at Two Separate Sites

The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III.

The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface

The interaction of MgADP with H+ -ATPase in rat liver mitochondria

The oxidation of sulfhydryl groups in mitochondrial F1-ATPase decreases the rate of its inactivation by the natural protein inhibitor

The role of mitochondrial ROS in antibacterial immunity.

Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis

Thread-grain transition of mitochondrial reticulum as a step of mitoptosis and apoptosis.

Uncoupling of respiration and oxidative phosphorylation in transformed mouse L929 fibroblasts induced by cocultivation with human erythroleukemic K562 cells or by tumor necrosis factor.

Zn2+ allows differentiation between two kinds of IF1-ATPase interaction in intact mitochondria

[Mitochondria-targeted antioxidant SkQR1 selectively protects MDR-negative cells against ionizing radiation]