List of works - Yaw Sing Tan

A comparison of the dynamics of pantothenate synthetase from M. tuberculosis and E. coli: Computational studies ⬇️

scientific article published on March 21, 2011

Accelerated Ligand-Mapping Molecular Dynamics Simulations for the Detection of Recalcitrant Cryptic Pockets and Occluded Binding Sites

scientific article published on 17 February 2022

An intramolecular tryptophan-condensation approach for peptide stapling.

scientific article published on 22 December 2017

Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells

scientific article published on 25 May 2021

Development of Cell-Permeable, Non-Helical Constrained Peptides to Target a Key Protein-Protein Interaction in Ovarian Cancer

scientific article published on 5 December 2016

Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein-protein interaction.

scientific article published on 12 April 2019

Incorporation of Putative Helix-Breaking Amino Acids in the Design of Novel Stapled Peptides: Exploring Biophysical and Cellular Permeability Properties

scientific article published on 20 June 2019

Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2

scientific article published in Scientific Reports

Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges.

scientific article published on 16 March 2018

Macrocyclized Extended Peptides: Inhibiting the Substrate-Recognition Domain of Tankyrase.

scientific article published on 13 January 2017

Role of the N-terminal lid in regulating the interaction of phosphorylated MDMX with p53.

scientific article published in December 2017

Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting

scientific article published on 01 April 2019

Stapled peptides as a new technology to investigate protein-protein interactions in human platelets.

scientific article published on 25 April 2018

Stereoisomerism of stapled peptide inhibitors of the p53-Mdm2 interaction: an assessment of synthetic strategies and activity profiles

scientific article published on 30 May 2019

Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides

scientific article published on 21 June 2019

Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide

article published in the Proceedings of the National Academy of Sciences of the United States of America

Ultrasensitive Detection of MCF-7 Cells with a Carbon Nanotube-Based Optoelectronic-Pulse Sensor Framework

scientific article published on 26 May 2022

List of works by Yaw Sing Tan