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Analysis of clonal expansions through the normal and premalignant human breast epithelium reveals the presence of luminal stem cells.

scientific article

Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations.

scientific article

Barrett oesophagus: lessons on its origins from the lesion itself

scientific article published on 04 November 2014

Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor.

scientific article

Bullying at Barts

scientific article published on 13 April 2012

Cell migration leads to spatially distinct but clonally related airway cancer precursors.

scientific article published on 18 February 2014

Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis

scientific article published on 01 May 1997

Clonal Transitions and Phenotypic Evolution in Barrett’s Esophagus

scientific article published in 2022

Clonal expansion in the human gut: mitochondrial DNA mutations show us the way.

scientific article

Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablation.

scientific article

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

scientific article published on 25 January 2010

Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia

scientific article published on 07 November 2008

Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells.

scientific article

Crypt fusion as a homeostatic mechanism in the human colon

scientific article published on 14 March 2019

Detection of intestinal metaplasia in Barrett's esophagus: an observational comparator study suggests the need for a minimum of eight biopsies.

scientific article published on 13 April 2007

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread

scientific article

Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo.

scientific article published on October 2008

Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus

scientific article published on 23 December 2015

Field cancerization in the GI tract.

scientific article published on August 2011

Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis.

scientific article

Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why?

scientific article published on April 2010

Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver

scientific article published in 2023

Identification of lineage-uncommitted, long-lived, label-retaining cells in healthy human esophagus and stomach, and in metaplastic esophagus.

scientific article

Inherited pathogenic mitochondrial DNA mutations and gastrointestinal stem cell populations

scientific article published on 05 November 2018

Intestinal stem cells

scientific article published on 01 January 2005

Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.

scientific article published on 13 June 2013

Mechanisms of disease: from stem cells to colorectal cancer.

scientific article

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.

scholarly article

Protection of mitochondrial genome integrity: a new stem cell property?

scientific article published on 01 January 2010

Quantification of crypt and stem cell evolution in the normal and neoplastic human colon

scientific article (publication date: 21 August 2014)

Re: Mitochondria and tumor progression in ulcerative colitis.

scientific article

Squamous cell carcinoma after radiofrequency ablation for Barrett's dysplasia.

scientific article published on April 2014

Stem cells and inflammation in the intestine.

scientific article published on January 2011

Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

scientific article published on 22 October 2013

Superficial Esophageal Mucosal Afferent Nerves May Contribute to Reflux Hypersensitivity in Nonerosive Reflux Disease.

scientific article published on 19 July 2017

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

scientific journal article

The Barrett's Gland in Phenotype Space.

scientific article published on 12 November 2014

The Complex, Clonal, and Controversial Nature of Barrett's Esophagus

scientific article

The clonal origins of dysplasia from intestinal metaplasia in the human stomach.

scientific article

The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

scientific article published on 18 February 2014

Use of methylation patterns to determine expansion of stem cell clones in human colon tissue.

scientific article published on 28 December 2010

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