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List of works by Michael J Ausserlechner

A conceptual view on glucocorticoid-lnduced apoptosis, cell cycle arrest and glucocorticoid resistance in lymphoblastic leukemia

scientific article published on December 2003

A drug library screen identifies Carbenoxolone as novel FOXO inhibitor that overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma

scientific article published on 07 October 2019

A novel Mcl1 variant inhibits apoptosis via increased Bim sequestration ⬇️

scientific article published on August 1, 2013

Altered procollagen mRNA expression during the progression of avian scleroderma.

scientific article published on October 1997

Apoptosis induced by the histone deacetylase inhibitor sodium butyrate in human leukemic lymphoblasts.

scientific article

BIRC5/Survivin as a target for glycolysis inhibition in high-stage neuroblastoma.

scientific article published on 6 July 2015

BIRC5/Survivin enhances aerobic glycolysis and drug resistance by altered regulation of the mitochondrial fusion/fission machinery.

scientific article

C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma.

scientific article published on 28 September 2014

C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy

scientific article

Characterization of the XIAP-Inhibiting Proanthocyanidin Fraction of the Aerial Parts of Ephedra sinica.

scientific article published on 24 May 2016

Chemiluminescence-based RNase protection assays for simultaneous quantification of procollagen mRNAs containing AU-rich regions

scientific article published on 01 March 1998

Crosstalk between Mitochondria and Cytoskeleton in Cardiac Cells

scientific article published on 16 January 2020

Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells.

scientific article published on February 2004

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

scientific article published on 5 July 2014

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells

scientific article

FOXO3-induced reactive oxygen species are regulated by BCL2L11 (Bim) and SESN3.

scientific article published on 20 February 2012

FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3.

scientific article published on 4 September 2017

FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

scientific article

Forkhead Domains of FOXO Transcription Factors Differ in both Overall Conformation and Dynamics

scientific article published on 24 August 2019

Functional analysis of the mutated Epstein-Barr virus oncoprotein LMP1(69del): implications for a new role of naturally occurring LMP1 variants.

scientific article published on December 2003

G1 arrest by p16INK4A uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression

scientific article published on 01 June 2005

Gene expression profiles of proliferating vs. G1/G0 arrested human leukemia cells suggest a mechanism for glucocorticoid-induced apoptosis.

scientific article published in March 2001

Lipidomic and Proteomic Alterations Induced by Even and Odd Medium-Chain Fatty Acids on Fibroblasts of Long-Chain Fatty Acid Oxidation Disorders

scientific article published in 2021

Mitochondria and FOXO3: breath or die

scientific article

Mitochondrial survivin - an Achilles' heel in cancer chemoresistance.

scientific article published on 29 July 2015

Modulating FOXO3 transcriptional activity by small, DBD-binding molecules

scientific article published on 4 December 2019

Modulation of Respiration and Mitochondrial Dynamics by SMAC-Mimetics for Combination Therapy in Chemoresistant Cancer

scientific article published on 09 July 2019

Nuclear FOXO3 predicts adverse clinical outcome and promotes tumor angiogenesis in neuroblastoma.

scientific article published on 18 October 2016

Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells ⬇️

scientific article

Premature aging of the immune system in children with juvenile idiopathic arthritis

scientific article published on 01 July 2008

Repaglinide Silences the FOXO3/Lumican Axis and Represses the Associated Metastatic Potential of Neuronal Cancer Cells

scientific article published on 18 December 2019

Resistance to glucocorticoid-induced apoptosis in lymphoblastic leukemia.

scientific article

Successful transplantation in a child with rapid progression of autosomal recessive polycystic kidney disease associated with a novel mutation.

scientific article published in May 2006

Targeting transcription factors by small compounds--Current strategies and future implications.

scientific article published on 11 December 2015

The Role of Mitochondria in the Mechanisms of Cardiac Ischemia-Reperfusion Injury

scientific article published on 06 October 2019

The anti-apoptotic protein BCL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression.

scientific article

The cell cycle inhibitor p16(INK4A) sensitizes lymphoblastic leukemia cells to apoptosis by physiologic glucocorticoid levels

scientific article published on 12 January 2001

The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.

scientific article published on 19 September 2009

The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species

scientific article

The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma

scientific article published on 22 March 2017

Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa

scientific article published on July 2013

Toll-like receptor 9 expression in breast and ovarian cancer is associated with poorly differentiated tumors

scientific article

Very long-/ and long Chain-3-Hydroxy Acyl CoA Dehydrogenase Deficiency correlates with deregulation of the mitochondrial fusion/fission machinery.

scientific article published on 19 February 2018

X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.

scientific article

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

scientific article

p53-induced apoptosis in the human T-ALL cell line CCRF-CEM.

scientific article published in November 1997

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