List of works - Renwick Dobson

"Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes.

scientific article published on 8 December 2017

A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals.

scientific article published on 6 April 2018

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

scientific article published in Nature Communications

A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis.

scientific article

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

scientific article

Analytical ultracentrifugation: still the gold standard that offers multiple solutions

scientific article published on 19 November 2020

Aromatic residues in the C-terminal helix of human apoC-I mediate phospholipid interactions and particle morphology.

scientific article

Biochemical characterization of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase (MurE) from Verrucomicrobium spinosum DSM 4136(T.)

scientific article (publication date: 2013)

Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5-7.5.

scientific article published on 17 July 2012

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

scientific article published on 10 July 2009

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana

scientific article

Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization

scientific article

Chromatic Bacteria - A Broad Host-Range Plasmid and Chromosomal Insertion Toolbox for Fluorescent Protein Expression in Bacteria

scientific article published on 12 December 2018

Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

scientific article published on 25 December 2009

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens

scientific article published on 30 August 2012

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera

scientific article published on 25 November 2011

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica

scientific article published on 29 October 2010

Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution

scientific article published in January 2016

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine kinase from methicillin-resistant Staphylococcus aureus.

scientific article published on 17 April 2014

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine-6-phosphate 2-epimerase from methicillin-resistant Staphylococcus aureus

scientific article published on 17 April 2014

Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus

scientific article published on 27 February 2013

Comparative Molecular Dynamics Simulations Provide Insight Into Antibiotic Interactions: A Case Study Using the Enzyme L,L-Diaminopimelate Aminotransferase (DapL)

scientific article published on 24 March 2020

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution

scientific article published on 17 January 2020

Conformational Dynamics and Allostery in Pyruvate Kinase.

scientific article

Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase.

scientific article published on 3 December 2007

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

scientific article

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis

scientific article

Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae

scientific article published on 28 June 2018

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

scientific article

Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate

scientific article published on 14 February 2009

Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii.

scientific article published on 24 December 2010

Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli

scientific article published on 25 December 2009

Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana

scientific article published on 27 October 2011

Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity

scientific article

Development of the procedures for high-yield expression and rapid purification of active recombinant Csk-homologous kinase (CHK): comparison of the catalytic activities of CHK and CSK.

scientific article published on 25 July 2010

Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds.

scientific article published on 9 November 2013

Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution

scientific article published on January 2017

Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate

scientific article

Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde.

scientific article published on February 2004

Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis

scientific article

Discovery of a novel circular single-stranded DNA virus from porcine faeces.

scientific article

Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine.

scientific article published on 13 August 2010

Dual diaminopimelate biosynthesis pathways in Bacteroides fragilis and Clostridium thermocellum

scientific article published on 14 May 2011

Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

scientific article published on 23 October 2017

Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain

scientific article

Evolution of quaternary structure in a homotetrameric enzyme

scientific article

Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface?

scientific article published on 15 November 2009

Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery

scientific article published on 10 March 2016

Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate

scientific article published on 31 January 2009

Federated repositories of X-ray diffraction images

scientific article

Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus

scientific article published on 26 November 2018

G-quadruplex structures bind to EZ-Tn5 transposase

scientific article published on 14 August 2020

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

scientific article published on 19 June 2015

Genomic and Biochemical Analysis of the Diaminopimelate and Lysine Biosynthesis Pathway in Verrucomicrobium spinosum: Identification and Partial Characterization of L,L-Diaminopimelate Aminotransferase and UDP-N-Acetylmuramoylalanyl-D-glutamyl-2,6-m

scientific article

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?

scientific article

Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae

scientific article published in 2024

Identification and Partial Characterization of a Novel UDP-N-Acetylenolpyruvoylglucosamine Reductase/UDP-N-Acetylmuramate:l-Alanine Ligase Fusion Enzyme from Verrucomicrobium spinosum DSM 4136(T).

scientific article published on 23 March 2016

Identification of the bona fide DHDPS from a common plant pathogen

scientific journal article

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

scientific journal article

Inhibition of Arabidopsis growth by the allelopathic compound azetidine-2-carboxylate is due to the low amino acid specificity of cytosolic prolyl-tRNA synthetase

scientific article published on 22 June 2016

Investigating the catalytic and regulatory mechanisms of dihydrodipicolinate synthase. ⬇️

2003 doctoral thesis by Renwick C. J. Dobson at University of Canterbury

Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues

scientific article

L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development

scientific article

L,L-diaminopimelate aminotransferase (DapL): a putative target for the development of narrow-spectrum antibacterial compounds.

scientific article

Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

scientific article published on 31 March 2021

Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen

scientific article published on 1 September 2021

Molecular characterisation of a novel cassava associated circular ssDNA virus

scientific article

Multi-wavelength analytical ultracentrifugation as a tool to characterise protein-DNA interactions in solution

scientific article published on 21 November 2020

Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme

scientific article

New flow control systems in capillarics: off valves

scientific article published on 09 December 2020

On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism

scientific article published on 21 November 2019

On the utility of fluorescence-detection analytical ultracentrifugation in probing biomolecular interactions in complex solutions: a case study in milk

scientific article published on 14 October 2020

Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis

scientific article published on 13 April 2019

Potential pathogenicity determinants in the genome of ‘Candidatus Liberibacter solanacearum’, the causal agent of zebra chip disease of potato

article by Jenna M. Gilkes et al published 21 February 2018 in Australasian Plant Pathology

Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus.

scientific article published on 28 June 2008

Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase.

scientific article

Quaternary variations in the structural assembly of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella multocida

scientific article published on 31 August 2020

Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase

scientific article published in October 2005

Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis

scientific article

Structural and Dynamic Requirements for Optimal Activity of the Essential Bacterial Enzyme Dihydrodipicolinate Synthase ⬇️

scientific article (publication date: 2012)

Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter

scientific article published on 13 February 2024

Structural and biophysical analysis of aHaemophilus influenzaetripartite ATP-independent periplasmic (TRAP) transporter

Structural and functional analysis of the GABARAP interaction motif (GIM).

scientific article

Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism

scientific article

Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition

scientific article

Structure and Function of N-Acetylmannosamine Kinases from Pathogenic Bacteria

scientific article published on 23 November 2020

Structure and evolution of a novel dimeric enzyme from a clinically important bacterial pathogen

scientific article

Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus

scientific article

Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter

scientific article published on 27 February 2023

Structure and mechanism of the tripartite ATP-independent periplasmic (TRAP) transporter

Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases

scientific article published on 10 March 2020

Structure-function analyses of alkylhydroperoxidase D from Streptococcus pneumoniae reveal an unusual three-cysteine active site architecture

scientific article published on 23 January 2020

Structure-function analyses of two plant meso-diaminopimelate decarboxylase isoforms reveal that active-site gating provides stereochemical control

scientific article published on 08 April 2019

Structure-function studies of the antibiotic target L,L-diaminopimelate aminotransferase from Verrucomicrobium spinosum reveal an unusual oligomeric structure

scientific article published on 01 June 2020

Sub-Ångstrom structure of collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations

scientific article published on 10 March 2020

Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target

scientific article published on 24 May 2018

Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.

scientific article

Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax

scientific article

Synthesis and incorporation of an advanced lipid peroxidation end-product building block into collagen mimetic peptides.

scientific article published on 12 July 2017

TRAPs: the ‘elevator-with-an-operator’ mechanism

scientific article published in February 2024

The C-terminal domain of Escherichia coli dihydrodipicolinate synthase (DHDPS) is essential for maintenance of quaternary structure and efficient catalysis

scientific article

The First Purification of Functional Proteins from the Unculturable, Genome-Reduced, Bottlenecked α-Proteobacterium 'Candidatus Liberibacter solanacearum'

scientific article published on 29 May 2019

The Molecular Basis for Escherichia coli O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability

scientific article published in 2021

The Quest for Novel Antimicrobial Compounds: Emerging Trends in Research, Development, and Technologies

article

The Sodium Sialic Acid Symporter From Staphylococcus aureus Has Altered Substrate Specificity.

scientific article published on 4 July 2018

The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus

scientific article published on 15 January 2020

The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution

scientific article

The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product ⬇️

scientific article published on June 4, 2012

The crystal structure of three site-directed mutants of Escherichia coli dihydrodipicolinate synthase: further evidence for a catalytic triad.

scientific article published in April 2004

The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance.

scientific article

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

scientific article published on 8 April 2016

The fitness challenge of studying molecular adaptation

scientific article published on 01 October 2019

The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate

scientific article

The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase

scientific article published on 25 September 2020

The preparation of (S)-aspartate semi-aldehyde appropriate for use in biochemical studies.

scientific article published in January 2003

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

scientific article

The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum

scientific article published on 29 February 2008

The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thaliana

scientific article

The quaternary structure of pyruvate kinase type 1 from Escherichia coli at low nanomolar concentrations

scientific article published on 2 October 2009

The rules of engagement for the nanRepressor- the regulator for sialic acid catabolism in pathogens

scholarly article

The self-association and thermal denaturation of caprine and bovine β-lactoglobulin.

scientific article published on 16 April 2018

The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily

scientific article published in 2022

The structure of human interleukin-11 reveals receptor-binding site features and structural differences from interleukin-6

scientific article

The structure of the extracellular domains of human interleukin 11 α-receptor reveals mechanisms of cytokine engagement

scientific article published on 24 April 2020

Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate.

scientific article

Tyrosine Latching of a Regulatory Gate Affords Allosteric Control of Aromatic Amino Acid Biosynthesis

scientific article

Ultra-high resolution crystal structure of recombinant caprine β-lactoglobulin

scientific article

List of works by Renwick Dobson

"Just a spoonful of sugar...": import of sialic acid across bacterial cell membranes.

A Three-Ring Circus: Metabolism of the Three Proteogenic Aromatic Amino Acids and Their Role in the Health of Plants and Animals.

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis.

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Analytical ultracentrifugation: still the gold standard that offers multiple solutions

Aromatic residues in the C-terminal helix of human apoC-I mediate phospholipid interactions and particle morphology.

Biochemical characterization of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase (MurE) from Verrucomicrobium spinosum DSM 4136(T.)

Bovine β-lactoglobulin is dimeric under imitative physiological conditions: dissociation equilibrium and rate constants over the pH range of 2.5-7.5.

Characterisation of dihydrodipicolinate synthase (DHDPS) from Bacillus anthracis.

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana

Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization

Chromatic Bacteria - A Broad Host-Range Plasmid and Chromosomal Insertion Toolbox for Fluorescent Protein Expression in Bacteria

Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from Agrobacterium tumefaciens

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the grapevine Vitis vinifera

Cloning, expression, purification and crystallization of dihydrodipicolinate synthase from the psychrophile Shewanella benthica

Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine kinase from methicillin-resistant Staphylococcus aureus.

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine-6-phosphate 2-epimerase from methicillin-resistant Staphylococcus aureus

Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus

Comparative Molecular Dynamics Simulations Provide Insight Into Antibiotic Interactions: A Case Study Using the Enzyme L,L-Diaminopimelate Aminotransferase (DapL)

Comparing the Conformational Stability of Pyruvate Kinase in the Gas Phase and in Solution

Conformational Dynamics and Allostery in Pyruvate Kinase.

Conformationally constrained diketopimelic acid analogues as inhibitors of dihydrodipicolinate synthase.

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis

Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

Crystallization and preliminary X-ray analysis of dihydrodipicolinate synthase from Clostridium botulinum in the presence of its substrate pyruvate

Crystallization and preliminary X-ray diffraction analysis of L,L-diaminopimelate aminotransferase (DapL) from Chlamydomonas reinhardtii.

Crystallization and preliminary X-ray diffraction analysis of diaminopimelate epimerase from Escherichia coli

Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana

Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity

Development of the procedures for high-yield expression and rapid purification of active recombinant Csk-homologous kinase (CHK): comparison of the catalytic activities of CHK and CSK.

Differential response of orthologous L,L-diaminopimelate aminotransferases (DapL) to enzyme inhibitory antibiotic lead compounds.

Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution

Dihydrodipicolinate synthase (DHDPS) from Escherichia coli displays partial mixed inhibition with respect to its first substrate, pyruvate

Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde.

Dimerization of Bacterial Diaminopimelate Epimerase Is Essential for Catalysis

Discovery of a novel circular single-stranded DNA virus from porcine faeces.

Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine.

Dual diaminopimelate biosynthesis pathways in Bacteroides fragilis and Clostridium thermocellum

Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain

Evolution of quaternary structure in a homotetrameric enzyme

Exploring the dihydrodipicolinate synthase tetramer: how resilient is the dimer-dimer interface?

Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery

Expression, purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Bacillus anthracis in the presence of pyruvate

Federated repositories of X-ray diffraction images

Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus

G-quadruplex structures bind to EZ-Tn5 transposase

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

Genomic and Biochemical Analysis of the Diaminopimelate and Lysine Biosynthesis Pathway in Verrucomicrobium spinosum: Identification and Partial Characterization of L,L-Diaminopimelate Aminotransferase and UDP-N-Acetylmuramoylalanyl-D-glutamyl-2,6-m

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase?

Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae

Identification and Partial Characterization of a Novel UDP-N-Acetylenolpyruvoylglucosamine Reductase/UDP-N-Acetylmuramate:l-Alanine Ligase Fusion Enzyme from Verrucomicrobium spinosum DSM 4136(T).

Identification of the bona fide DHDPS from a common plant pathogen

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

Inhibition of Arabidopsis growth by the allelopathic compound azetidine-2-carboxylate is due to the low amino acid specificity of cytosolic prolyl-tRNA synthetase

Investigating the catalytic and regulatory mechanisms of dihydrodipicolinate synthase. ⬇️

Irreversible inhibition of dihydrodipicolinate synthase by 4-oxo-heptenedioic acid analogues

L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development

L,L-diaminopimelate aminotransferase (DapL): a putative target for the development of narrow-spectrum antibacterial compounds.

Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism

Molecular basis of a redox switch: molecular dynamics simulations and surface plasmon resonance provide insight into reduced and oxidised angiotensinogen

Molecular characterisation of a novel cassava associated circular ssDNA virus

Multi-wavelength analytical ultracentrifugation as a tool to characterise protein-DNA interactions in solution

Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme

New flow control systems in capillarics: off valves

On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism

On the utility of fluorescence-detection analytical ultracentrifugation in probing biomolecular interactions in complex solutions: a case study in milk

Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis

Potential pathogenicity determinants in the genome of ‘Candidatus Liberibacter solanacearum’, the causal agent of zebra chip disease of potato

Purification, crystallization and preliminary X-ray diffraction studies to near-atomic resolution of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus.

Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase.