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List of works by Adam Grundhoff

A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence

scientific article published on 28 July 2015

A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment

scientific article published on 31 October 2019

A comparative metagenome survey of the fecal microbiota of a breast- and a plant-fed Asian elephant reveals an unexpectedly high diversity of glycoside hydrolase family enzymes

scientific article

A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo.

scientific article published on 09 September 2010

A microRNA Encoded by Kaposi Sarcoma-Associated Herpesvirus Promotes B-Cell Expansion In Vivo ⬇️

scientific article published on November 20, 2012

Activation of the B cell antigen receptor triggers reactivation of latent Kaposi's sarcoma-associated herpesvirus in B cells.

scientific article published on 15 May 2013

BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells

scientific article

Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription

scientific article published on 10 July 2014

CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X.

scientific article published on 3 September 2015

Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C

scientific article

Close relationship of ruminant pestiviruses and classical Swine Fever virus

scientific article

Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load ⬇️

scientific article published on December 9, 2010

Complete Genome Sequence of Bovine Pestivirus Strain PG-2, a Second Member of the Tentative Pestivirus Species Giraffe.

scientific article published on 15 May 2014

Complete Genome Sequence of a Novel Human Gammapapillomavirus Isolated from Skin.

scientific article

Complete genome sequence of Pig-tailed macaque rhadinovirus 2 and its evolutionary relationship with rhesus macaque rhadinovirus and human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus.

scientific article published on 21 January 2015

Complete genome sequence of pronghorn virus, a pestivirus.

scientific article

Comprehensive mapping and analysis of Kaposi's sarcoma-associated herpesvirus 3' UTRs identify differential posttranscriptional control of gene expression in lytic versus latent infection.

scientific article published on 25 September 2013

Computational Prediction of Viral miRNAs ⬇️

scientific article published on 01 January 2011

Correction: Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load.

scientific article

DAMIAN: an open source bioinformatics tool for fast, systematic and cohort based analysis of microorganisms in diagnostic samples

scientific article published on 14 November 2019

Deep metagenome and metatranscriptome analyses of microbial communities affiliated with an industrial biogas fermenter, a cow rumen, and elephant feces reveal major differences in carbohydrate hydrolysis strategies

scientific article

Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells

scientific article published on 27 July 2011

Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.

scientific article

Dynamic changes of circulating miRNAs induced by the Ebola virus vaccine VSV-EBOV

scientific article published on 21 September 2018

Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer.

scientific article published in May 2015

Epigenetic control in Kaposi sarcoma-associated herpesvirus infection and associated disease

scientific article published on 26 March 2020

Epigenetic manipulation of host chromatin by Kaposi sarcoma-associated herpesvirus: a tumor-promoting factor?

scientific article published on 9 August 2017

Epstein-Barr virus maintains lymphomas via its miRNAs.

scientific article published on 18 March 2013

Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples.

scientific article published on 13 May 2015

Exploring the DNA binding interactions of the Kaposi's sarcoma-associated herpesvirus lytic switch protein by selective amplification of bound sequences in vitro

scientific article published in March 2006

First report of Escherichia coli co-producing NDM-1 and OXA-232.

scientific article published on 16 September 2016

Functional Dissection of an Alternatively Spliced Herpesvirus Gene by Splice Site Mutagenesis

scientific article published on 24 February 2016

Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types

scientific article published on 07 May 2018

Generation of high-titre virus stocks using BrK.219, a B-cell line infected stably with recombinant Kaposi's sarcoma-associated herpesvirus

scientific article

High Abundance and Genetic Variability of Atypical Porcine Pestivirus in Pigs from Europe and Asia.

scientific article published in December 2017

High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens.

scientific article

High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms

scientific article published on 24 August 2020

Highly divergent hepaciviruses from African cattle

scientific article

Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice

scientific article published in 2013

Identification of a Novel Hepacivirus in Domestic Cattle from Germany

scientific article (publication date: 29 April 2015)

Identification of a novel clade of group A rotaviruses in fatally diseased domestic pigeons in Europe

scientific article published on 28 November 2018

Identification of viral microRNAs

scientific article published on 01 January 2007

Identification of virus-encoded microRNAs in divergent Papillomaviruses

scientific article published on 26 July 2018

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells

scientific article

In Vitro Replication Assay for Merkel Cell Polyomavirus (MCPyV).

scientific article published on 3 August 2015

Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles

scientific article

Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis.

scientific article published on January 2004

Influence of ND10 components on epigenetic determinants of early KSHV latency establishment

scientific article

Investigation of Viral and Host Chromatin by ChIP-PCR or ChIP-Seq Analysis

scientific article

KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition.

scientific article published in December 2011

Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Targeting of a dCas9-Based Transcription Activator to the ORF50 Promoter

scientific article published on 27 August 2020

Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region.

scientific article published on 9 February 2011

Merkel cell polyomavirus detection in Merkel cell cancer tumors in Northern Germany using PCR and protein expression.

scientific article published on 17 October 2013

Merkel cell polyomavirus, a highly prevalent virus with tumorigenic potential.

scientific article published on 05 October 2015

Metagenome survey of a multispecies and alga-associated biofilm revealed key elements of bacterial-algal interactions in photobioreactors

scientific article (publication date: October 2013)

Micro RNAs of Epstein-Barr Virus Promote Cell Cycle Progression and Prevent Apoptosis of Primary Human B Cells ⬇️

scientific article published on August 19, 2010

MicroRNA Profiling During Human Keratinocyte Differentiation Using a Quantitative Real-Time PCR Method ⬇️

scientific article published on January 1, 2013

Molecular consequences of SARS-CoV-2 liver tropism

scientific article published on 28 March 2022

Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection

scientific article published on 09 March 2009

Next-generation sequence analysis of the genome of RFHVMn, the macaque homolog of Kaposi's sarcoma (KS)-associated herpesvirus, from a KS-like tumor of a pig-tailed macaque.

scientific article published on 09 October 2013

Next-generation sequencing of peripheral B-lineage cells pinpoints the circulating clonotypic cell pool in multiple myeloma

scientific article published on 21 April 2014

Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus

scientific article

Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus

scientific article

Osmotic Stress Interferes with DNA Damage Response and H2AX Phosphorylation in Human Keratinocytes

scientific article published in 2022

Pegivirus Infection in Domestic Pigs, Germany

scientific article (publication date: July 2016)

Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression.

scientific article published on July 2017

Piscine Orthoreovirus 3 Is Not the Causative Pathogen of Proliferative Darkening Syndrome (PDS) of Brown Trout ()

scientific article published on 28 January 2019

Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice.

scientific article

Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor

scientific article

RNAs in the virion of Kaposi's sarcoma-associated herpesvirus.

scientific article published on August 2005

RNF40 regulates gene expression in an epigenetic context-dependent manner.

scientific article published on 16 February 2017

Rapid metagenomic diagnostics for suspected outbreak of severe pneumonia

scientific article published on June 2014

Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample

scientific article

Replication of Merkel cell polyomavirus induces reorganization of promyelocytic leukemia nuclear bodies

scientific article published on 30 August 2016

Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome.

scientific article

Repression of Human Papillomavirus Oncogene Expression under Hypoxia Is Mediated by PI3K/mTORC2/AKT Signaling

scientific article published on 12 February 2019

Runx1 is essential at two stages of early murine B-cell development.

scientific article published on 23 May 2013

Spontaneous lung metastasis formation of human Merkel cell carcinoma cell lines transplanted into scid mice

scientific article published on 5 April 2017

Successful retreatment of a patient with chronic hepatitis C genotype 2k/1b virus with ombitasvir/paritaprevir/ritonavir plus dasabuvir.

scientific article published on 18 January 2017

Suspected encephalitis with Candida tropicalis and Fusarium detected by unbiased RNA sequencing

scientific article published on 29 July 2016

T-Cell Receptor Diversity and the Control of T-Cell Homeostasis Mark Ebola Virus Disease Survival in Humans

scientific article published on 01 November 2018

TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease

scientific article published on 01 January 2019

The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Permits Replication of Terminal Repeat-Containing Plasmids

article published in 2003

The acidic protein rich in leucines Anp32b is an immunomodulator of inflammation in mice

scientific article published on 19 March 2019

The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes.

scientific article

The landscape of viral associations in human cancers

scientific article published on 05 February 2020

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids.

scientific article

Virus-encoded microRNAs ⬇️

scientific article published on January 31, 2011

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