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List of works by Adam Grundhoff

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Inefficient establishment of KSHV latency suggests an additional role for continued lytic replication in Kaposi sarcoma pathogenesis.

scientific article published on January 2004
Virus-encoded microRNAs

scientific article published on January 31, 2011
The epigenetic landscape of latent Kaposi sarcoma-associated herpesvirus genomes.

scientific article
Micro RNAs of Epstein-Barr Virus Promote Cell Cycle Progression and Prevent Apoptosis of Primary Human B Cells

scientific article published on August 19, 2010
The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus permits replication of terminal repeat-containing plasmids.

scientific article
Epstein-Barr virus maintains lymphomas via its miRNAs.

scientific article published on 18 March 2013
Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription

scientific article published on 10 July 2014
KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition.

scientific article published in December 2011
Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C

scientific article
Murine Polyomavirus encodes a microRNA that cleaves early RNA transcripts but is not essential for experimental infection

scientific article published on 09 March 2009
High-affinity Rb binding, p53 inhibition, subcellular localization, and transformation by wild-type or tumor-derived shortened Merkel cell polyomavirus large T antigens.

scientific article
RNAs in the virion of Kaposi's sarcoma-associated herpesvirus.

scientific article published on August 2005
A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo.

scientific article published on 09 September 2010
CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X.

scientific article published on 3 September 2015
A microRNA Encoded by Kaposi Sarcoma-Associated Herpesvirus Promotes B-Cell Expansion In Vivo

scientific article published on November 20, 2012
Identification of a Novel Hepacivirus in Domestic Cattle from Germany

scientific article (publication date: 29 April 2015)
Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity.

scientific article
Presence of atypical porcine pestivirus (APPV) genomes in newborn piglets correlates with congenital tremor

scientific article
Persistent KSHV Infection Increases EBV-Associated Tumor Formation In Vivo via Enhanced EBV Lytic Gene Expression.

scientific article published on July 2017
Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice

scientific article published in 2013
Replication, gene expression and particle production by a consensus Merkel Cell Polyomavirus (MCPyV) genome.

scientific article
Evaluation of Unbiased Next-Generation Sequencing of RNA (RNA-seq) as a Diagnostic Method in Influenza Virus-Positive Respiratory Samples.

scientific article published on 13 May 2015
Highly divergent hepaciviruses from African cattle

scientific article
Influence of ND10 components on epigenetic determinants of early KSHV latency establishment

scientific article
Activation of the B cell antigen receptor triggers reactivation of latent Kaposi's sarcoma-associated herpesvirus in B cells.

scientific article published on 15 May 2013
Rapid metagenomic diagnostics for suspected outbreak of severe pneumonia

scientific article published on June 2014
Metagenome survey of a multispecies and alga-associated biofilm revealed key elements of bacterial-algal interactions in photobioreactors

scientific article (publication date: October 2013)
Deep metagenome and metatranscriptome analyses of microbial communities affiliated with an industrial biogas fermenter, a cow rumen, and elephant feces reveal major differences in carbohydrate hydrolysis strategies

scientific article
Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome contains a duplication of a long unique-region fragment within the terminal repeat region.

scientific article published on 9 February 2011
Exploring the DNA binding interactions of the Kaposi's sarcoma-associated herpesvirus lytic switch protein by selective amplification of bound sequences in vitro

scientific article published in March 2006
Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells

scientific article published on 27 July 2011
Runx1 is essential at two stages of early murine B-cell development.

scientific article published on 23 May 2013
Next-generation sequence analysis of the genome of RFHVMn, the macaque homolog of Kaposi's sarcoma (KS)-associated herpesvirus, from a KS-like tumor of a pig-tailed macaque.

scientific article published on 09 October 2013
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer.

scientific article published in May 2015
A comparative metagenome survey of the fecal microbiota of a breast- and a plant-fed Asian elephant reveals an unexpectedly high diversity of glycoside hydrolase family enzymes

scientific article
Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles

scientific article
Pregnancy-Related Immune Adaptation Promotes the Emergence of Highly Virulent H1N1 Influenza Virus Strains in Allogenically Pregnant Mice.

scientific article
Identification of viral microRNAs

scientific article published on 01 January 2007
A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence

scientific article published on 28 July 2015
Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load

scientific article published on December 9, 2010
Close relationship of ruminant pestiviruses and classical Swine Fever virus

scientific article
Novel poly-uridine insertion in the 3'UTR and E2 amino acid substitutions in a low virulent classical swine fever virus

scientific article
Comprehensive mapping and analysis of Kaposi's sarcoma-associated herpesvirus 3' UTRs identify differential posttranscriptional control of gene expression in lytic versus latent infection.

scientific article published on 25 September 2013
Generation of high-titre virus stocks using BrK.219, a B-cell line infected stably with recombinant Kaposi's sarcoma-associated herpesvirus

scientific article
Recovery of the first full-length genome sequence of a parapoxvirus directly from a clinical sample

scientific article
Generation of a novel next-generation sequencing-based method for the isolation of new human papillomavirus types

scientific article published on 07 May 2018
RNF40 regulates gene expression in an epigenetic context-dependent manner.

scientific article published on 16 February 2017
The landscape of viral associations in human cancers

scientific article published on 05 February 2020
Open chromatin structures regulate the efficiencies of pre-RC formation and replication initiation in Epstein-Barr virus

scientific article
High Abundance and Genetic Variability of Atypical Porcine Pestivirus in Pigs from Europe and Asia.

scientific article published in December 2017

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