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List of works by Hernando A del Portillo Obando

A functional microengineered model of the human splenon-on-a-chip

scientific article published on 24 March 2014

A new computational approach redefines the subtelomeric vir superfamily of Plasmodium vivax.

scientific article

A reduced risk of infection with Plasmodium vivax and clinical protection against malaria are associated with antibodies against the N terminus but not the C terminus of merozoite surface protein 1.

scientific article published on May 2006

A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax

scientific article

Advances toward the development of an asexual blood stage MSP-1 vaccine of Plasmodium vivax.

scientific article

Analysis of single-nucleotide polymorphisms in the crt-o and mdr1 genes of Plasmodium vivax among chloroquine-resistant isolates from the Brazilian Amazon region

scientific article published on 18 May 2009

Antigenic properties of the merozoite surface protein 1 gene of Plasmodium vivax

scientific article published in August 1999

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

scientific article

Biological properties of extracellular vesicles and their physiological functions.

scientific article published on 14 May 2015

Characterisation of the Cdc2-related kinase 2 gene from Plasmodium knowlesi and P. berghei.

scientific article published in September 1998

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

scientific article published on 25 June 2018

Circumsporozoite gene of a Plasmodium falciparum strain from Thailand

scientific article published in July 1987

Comparison of diagnostic methods for the detection and quantification of the four sympatric Plasmodium species in field samples from Papua New Guinea

scientific article published on 14 December 2010

Comparison of introns in a cdc2-homologous gene within a number of Plasmodium species.

scientific article published in May 1995

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles.

scientific article

Corrigendum: Spleen-Dependent Immune Protection Elicited by CpG Adjuvanted Reticulocyte-Derived Exosomes from Malaria Infection Is Associated with Changes in T Cell Subsets' Distribution.

scientific article published on January 2016

EVpedia: a community web portal for extracellular vesicles research

scientific article

Effect of immunosuppression in miRNAs from extracellular vesicles of colorectal cancer and their influence on the pre-metastatic niche

scientific article published on 01 August 2019

Evaluation of the acquired immune responses to Plasmodium vivax VIR variant antigens in individuals living in malaria-endemic areas of Brazil

scientific article

Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.

scientific article published on 27 April 2001

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine

scientific article

Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections.

scientific article

Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum.

scientific article published on 5 September 2006

Expression levels of pvcrt-o and pvmdr-1 are associated with chloroquine resistance and severe Plasmodium vivax malaria in patients of the Brazilian Amazon.

scientific article

Expression of non-TLR pattern recognition receptors in the spleen of BALB/c mice infected with Plasmodium yoelii and Plasmodium chabaudi chabaudi AS.

scientific article published in May 2012

Extracellular vesicles in parasitic diseases

scientific article

Functional analysis of Plasmodium vivax VIR proteins reveals different subcellular localizations and cytoadherence to the ICAM-1 endothelial receptor.

scientific article published on 28 December 2011

Genetic immunization of BALB/c mice with a plasmid bearing the gene coding for a hybrid merozoite surface protein 1-hepatitis B virus surface protein fusion protects mice against lethal Plasmodium chabaudi chabaudi PC1 infection

scientific article

Heat shock induction of apoptosis in promastigotes of the unicellular organism Leishmania (Leishmania) amazonensis

scientific article published on 01 May 1996

Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication.

scientific article published on 26 November 2017

Human IgG responses against the N-terminal region of the Merozoite Surface Protein 1 of Plasmodium vivax

scientific article

Human Splenon-on-a-chip: Design and Validation of a Microfluidic Model Resembling the Interstitial Slits and the Close/Fast and Open/Slow Microcirculations

Imaging of the spleen in malaria.

scientific article published on 31 August 2013

In vivo and in vitro characterization of a Plasmodium liver stage-specific promoter

scientific article (publication date: 2015)

Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria

scientific article published on 02 April 2009

Intravital microscopy of the spleen: quantitative analysis of parasite mobility and blood flow

scientific article

Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite

scientific article published on September 2009

Malaria parasites contain two identical copies of an elongation factor 1 alpha gene.

scientific article published in July 1998

Malaria parasites lacking eef1a have a normal S/M phase yet grow more slowly due to a longer G1 phase.

scientific article published in December 2003

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Mining the malaria transcriptome.

scientific article

Molecular analysis of Plasmodium vivax relapses using the MSP1 molecule as a genetic marker.

scientific article published in February 1998

Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study

scientific article published on 17 February 2017

Naturally-acquired humoral immune responses against the N- and C-termini of the Plasmodium vivax MSP1 protein in endemic regions of Brazil and Papua New Guinea using a multiplex assay

scientific article

On cytoadhesion of Plasmodium vivax: raison d'être?

scientific article published on August 2011

On the cytoadhesion of Plasmodium vivax-infected erythrocytes

scientific article published in August 2010

Origins of sequence diversity in the malaria vaccine candidate merozoite surface protein-2 (MSP-2) in Amazonian isolates of Plasmodium falciparum.

scientific article published on 5 April 2006

Paucity of Plasmodium vivax mature schizonts in peripheral blood is associated with their increased cytoadhesive potential

scientific article published on 9 January 2014

Placental infection with Plasmodium vivax: a histopathological and molecular study

scientific article published on 10 October 2012

Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence

scientific article published on 02 June 2020

Plasmodium falciparum: DBL-1 var sequence analysis in field isolates from central Brazil.

scientific article published in June 2000

Plasmodium falciparum: epidemiological studies on the circumsporozoite gene

scientific article published on 01 December 1987

Plasmodium falciparum: new vector with bi-directional promoter activity to stably express transgenes

scientific article published in January 2003

Plasmodium vivax VIR Proteins Are Targets of Naturally-Acquired Antibody and T Cell Immune Responses to Malaria in Pregnant Women

scientific article

Plasmodium vivax and the importance of the subtelomeric multigene vir superfamily.

scientific article

Plasmodium vivax epidemiology in Ethiopia 2000-2020: A systematic review and meta-analysis

scientific article published on 15 September 2021

Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile.

scientific article

Plasmodium vivax malaria in Mali: a study from three different regions

scientific article (publication date: 5 December 2012)

Plasmodium vivax spleen-dependent genes encode antigens associated with cytoadhesion and clinical protection

scientific article published on 21 May 2020

Plasmodium vivax: cloning and expression of a major blood-stage surface antigen.

scientific article

Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays

scientific article

Postmortem characterization of patients with clinical diagnosis of Plasmodium vivax malaria: to what extent does this parasite kill?

scientific article published on 6 July 2012

Pregnancy and malaria exposure are associated with changes in the B cell pool and in plasma eotaxin levels

scientific article published on 18 August 2014

Production of recombinant PvDBPII, receptor binding domain of Plasmodium vivax Duffy binding protein, and evaluation of immunogenicity to identify an adjuvant formulation for vaccine development.

scientific article published on 11 November 2015

Progress in imaging methods: insights gained into Plasmodium biology

scientific article

Proinflammatory responses and higher IL-10 production by T cells correlate with protection against malaria during pregnancy and delivery outcomes

scientific article published on 27 February 2015

Promoter regions of Plasmodium vivax are poorly or not recognized by Plasmodium falciparum

scientific article published on 21 February 2007

Proteomics study of human cord blood reticulocyte-derived exosomes

scientific article published in Scientific Reports

Red blood cells derived from peripheral blood and bone marrow CD34⁺ human haematopoietic stem cells are permissive to Plasmodium parasites infection

scientific article published on September 2013

Relapses contribute significantly to the risk of Plasmodium vivax infection and disease in Papua New Guinean children 1-5 years of age.

scientific article published on 10 September 2012

Removal of leucocytes from Plasmodium vivax-infected blood.

scientific article published in April 1994

Reticulocyte-prone malaria parasites predominantly invade CD71hi immature cells: implications for the development of an in vitro culture for Plasmodium vivax.

scientific article

Second form in a segment of the merozoite surface protein 1 gene of Plasmodium vivax among isolates from Rondônia (Brazil).

scientific article

Serum-derived exosomes from non-viremic animals previously exposed to the porcine respiratory and reproductive virus contain antigenic viral proteins

scientific article

Sex-specific and blood meal-induced proteins of Anopheles gambiae midguts: analysis by two-dimensional gel electrophoresis ⬇️

scientific article

Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals

scientific article published on 06 July 2015

Size-exclusion chromatography-based enrichment of extracellular vesicles from urine samples

scientific article

Spleen rupture in a case of untreated Plasmodium vivax infection.

scientific article

Spleen-Dependent Immune Protection Elicited by CpG Adjuvanted Reticulocyte-Derived Exosomes from Malaria Infection Is Associated with Changes in T cell Subsets' Distribution

scientific article

Strain-specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage-clearance escape.

scientific article published on October 2010

Sudden spleen rupture in a Plasmodium vivax-infected patient undergoing malaria treatment.

scientific article published on 13 February 2018

Talking to each other to initiate sexual differentiation.

scientific article published in May 2013

Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections

scientific article published in Scientific Reports

The Role of Extracellular Vesicles in Modulating the Host Immune Response during Parasitic Infections

scientific article published on 08 September 2014

The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites

scientific article

Variant genes and the spleen in Plasmodium vivax malaria.

scientific article

Variant proteins of Plasmodium vivax are not clonally expressed in natural infections.

scientific article published on November 2005

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