List of works - Stefan Rüdiger

3D DOSY-TROSY to determine the translational diffusion coefficient of large protein complexes.

scientific article published on 8 November 2010

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

scientific article

A script to highlight hydrophobicity and charge on protein surfaces.

scientific article published on 13 October 2015

Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

scientific article published on 29 January 2020

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network

scientific article

Behind closed gates - chaperones and charged residues determine protein fate

scientific article published on 30 April 2020

Binding specificity of Escherichia coli trigger factor ⬇️

scientific article published on November 27, 2001

Binding specificity of an alpha-helical protein sequence to a full-length Hsp70 chaperone and its minimal substrate-binding domain

scientific article published on 01 November 2006

Correlation of levels of folded recombinant p53 in escherichia coli with thermodynamic stability in vitro

scientific article published on 22 June 2007

Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded

scientific article

Dancing with the Diva: Hsp90-Client Interactions.

scientific article

Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTpp

scientific article published on 3 October 2012

Expressed protein ligation for a large dimeric protein

scientific article published on 18 February 2011

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System

scientific article published on 26 April 2018

Hsp90 interaction with clients.

scientific article published on 09 January 2015

Hsp90 structure and function studied by NMR spectroscopy.

scientific article

Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone.

scientific article

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations

scientific article

MAP7 family proteins regulate kinesin-1 recruitment and activation

scientific article published on 15 February 2019

Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?

scientific article

Modulation of substrate specificity of the DnaK chaperone by alteration of a hydrophobic arch

scientific article published on 01 December 2000

Molecular basis for regulation of the heat shock transcription factor sigma32 by the DnaK and DnaJ chaperones.

scientific article

Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2

scientific article

Multistep mechanism of substrate binding determines chaperone activity of Hsp70

scientific article published on 01 July 2000

Novel Hsp90 partners discovered using complementary proteomic approaches

scientific article

Picky Hsp90-Every Game with Another Mate

scientific article

Production and purification of human Hsp90β in Escherichia coli

scientific article

Recombinant production and purification of the human protein Tau

scientific article published on 01 December 2018

Regulatory region C of the E. coli heat shock transcription factor, sigma32, constitutes a DnaK binding site and is conserved among eubacteria.

scientific article published on March 1996

Studying protein-protein interactions using peptide arrays.

scientific article

Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.

scientific article

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation

scientific article published on 25 November 2020

The central region of HDM2 provides a second binding site for p53.

scholarly article

The conserved helix C region in the superfamily of interferon-gamma /interleukin-10-related cytokines corresponds to a high-affinity binding site for the HSP70 chaperone DnaK.

scientific article

The mechanism of Hsp90-induced oligomerizaton of Tau

scientific article published on 13 March 2020

The structure and interactions of the proline-rich domain of ASPP2

scientific article

The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.

scientific article published in June 2012

Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.

scientific article published in May 2001

Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled

scientific article published on 12 March 2012

List of works by Stefan Rüdiger

3D DOSY-TROSY to determine the translational diffusion coefficient of large protein complexes.

A peptide that binds and stabilizes p53 core domain: chaperone strategy for rescue of oncogenic mutants

A script to highlight hydrophobicity and charge on protein surfaces.

Arginine π-stacking drives binding to fibrils of the Alzheimer protein Tau

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network

Behind closed gates - chaperones and charged residues determine protein fate

Binding specificity of Escherichia coli trigger factor ⬇️

Binding specificity of an alpha-helical protein sequence to a full-length Hsp70 chaperone and its minimal substrate-binding domain

Correlation of levels of folded recombinant p53 in escherichia coli with thermodynamic stability in vitro

Critical scaffolding regions of the tumor suppressor Axin1 are natively unfolded

Dancing with the Diva: Hsp90-Client Interactions.

Determining biophysical protein stability in lysates by a fast proteolysis assay, FASTpp

Expressed protein ligation for a large dimeric protein

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System

Hsp90 interaction with clients.

Hsp90 structure and function studied by NMR spectroscopy.

Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone.

Large extent of disorder in Adenomatous Polyposis Coli offers a strategy to guard Wnt signalling against point mutations

MAP7 family proteins regulate kinesin-1 recruitment and activation

Messing up disorder: how do missense mutations in the tumor suppressor protein APC lead to cancer?

Modulation of substrate specificity of the DnaK chaperone by alteration of a hydrophobic arch

Molecular basis for regulation of the heat shock transcription factor sigma32 by the DnaK and DnaJ chaperones.

Molecular basis of the interaction between the antiapoptotic Bcl-2 family proteins and the proapoptotic protein ASPP2

Multistep mechanism of substrate binding determines chaperone activity of Hsp70

Novel Hsp90 partners discovered using complementary proteomic approaches

Picky Hsp90-Every Game with Another Mate

Production and purification of human Hsp90β in Escherichia coli

Recombinant production and purification of the human protein Tau

Regulatory region C of the E. coli heat shock transcription factor, sigma32, constitutes a DnaK binding site and is conserved among eubacteria.

Studying protein-protein interactions using peptide arrays.

Sulforaphane inhibits pancreatic cancer through disrupting Hsp90-p50(Cdc37) complex and direct interactions with amino acids residues of Hsp90.

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation

The central region of HDM2 provides a second binding site for p53.

The conserved helix C region in the superfamily of interferon-gamma /interleukin-10-related cytokines corresponds to a high-affinity binding site for the HSP70 chaperone DnaK.

The mechanism of Hsp90-induced oligomerizaton of Tau

The structure and interactions of the proline-rich domain of ASPP2

The vertebrate mitotic checkpoint protein BUBR1 is an unusual pseudokinase.

Tuning of chaperone activity of Hsp70 proteins by modulation of nucleotide exchange.

Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled