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List of works by Joanna B Strosznajder

A novel mechanism of non-Aβ component of Alzheimer's disease amyloid (NAC) neurotoxicity. Interplay between p53 protein and cyclin-dependent kinase 5 (Cdk5).

scientific article

ATP a potent regulator of inositol phospholipids-phospholipase C and lipid mediators in brain cortex

scientific article published on 01 January 1996

Activated neutrophils oxidize extracellular proteins of endothelial cells in culture: effect of nitric oxide donors

scientific article

Activation of constitutive nitric oxide synthase(s) and absence of inducible isoform in aged rat brain

scientific article published in March 2003

Activation of ethanolamine phospholipase A2 in Brain during ischemia.

scientific article published in October 1982

Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus

scientific article

Acute Systemic Inflammatory Response Alters Transcription Profile of Genes Related to Immune Response and Ca2+ Homeostasis in Hippocampus; Relevance to Neurodegenerative Disorders

scientific article published on 22 October 2020

Age-related alteration of activity and gene expression of endothelial nitric oxide synthase in different parts of the brain in rats

scientific article published in November 2004

Age-related alteration of poly(ADP-ribose) polymerase activity in different parts of the brain

scientific article published on 01 January 2000

Age-related changes of GABA-activated chloride channel properties in brain cortex synaptic plasma membrane: evidence for phospholipase involvement.

scientific article

Aggregated beta amyloid peptide 1-40 decreases Ca2+- and cholinergic receptor-mediated phosphoinositide degradation by alteration of membrane and cytosolic phospholipase C in brain cortex

scientific article published on February 2000

Aging diminishes serotonin-stimulated arachidonic acid uptake and cholinergic receptor-activated arachidonic acid release in rat brain cortex membrane.

scientific article

Aging modulates calcium-dependent phosphatidylinositol degradation by cerebral cortex synaptic plasma membrane phospholipases

scientific article published in January 1994

Aging modulates nitric oxide synthesis and cGMP levels in hippocampus and cerebellum. Effects of amyloid beta peptide.

scientific article published in August 1998

Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders.

scientific article published on 3 January 2017

Alpha-synuclein and its neurotoxic fragment inhibit dopamine uptake into rat striatal synaptosomes. Relationship to nitric oxide

scientific article published on 20 March 2006

Alpha-synuclein induced cell death in mouse hippocampal (HT22) cells is mediated by nitric oxide-dependent activation of caspase-3.

scientific article published on 16 July 2010

Alpha-synuclein potentiates Ca2+ influx through voltage-dependent Ca2+ channels

scientific article published in December 2006

Alteration of GSK-3β in the hippocampus and other brain structures after chronic paraquat administration in rats.

scientific article

Alteration of phosphatidylinositol transfer protein during global brain ischemia-reperfusion in gerbils.

scientific article published in October 2002

Alteration of phosphoinositide degradation by cytosolic and membrane-bound phospholipases after forebrain ischemia-reperfusion in gerbil: effects of amyloid beta peptide

scientific article

Alterations of Transcription of Genes Coding Anti-oxidative and Mitochondria-Related Proteins in Amyloid β Toxicity: Relevance to Alzheimer's Disease

scientific article published on 16 November 2019

Alterations of cyclin dependent kinase 5 expression and phosphorylation in amyloid precursor protein (APP)-transfected PC12 cells.

scientific article

Alzheimer's amyloid-β peptide disturbs P2X7 receptor-mediated circadian oscillations of intracellular calcium.

scientific article published on January 2016

Alzheimer's disease genetic mutation evokes ultrastructural alterations: correlation to an intracellular Abeta deposition and the level of GSK-3beta-P(Y216) phosphorylated form.

scientific article published on 6 June 2009

Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs.

scientific article published on January 1996

Amyloid beta enhances cytosolic phospholipase A2 level and arachidonic acid release via nitric oxide in APP-transfected PC12 cells.

scientific article

Amyloid beta peptide 25-35 modulates hydrolysis of phosphoinositides by membrane phospholipase(s) C of adult brain cortex

scientific article published on April 1999

Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons

scientific article

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

scientific article

Arachidonate transport through the blood-retina and blood-brain barrier of the rat after reperfusion of varying duration following complete cerebral ischemia.

scientific article published in April 1998

Arachidonate transport through the blood-retina and blood-brain barrier of the rat during aging

scientific article published on 01 May 1996

Association between genetic and environmental factors and the risk of Alzheimer's disease.

scientific article published in January 2008

Association between plasma biomarkers, CDK5 polymorphism and the risk of Alzheimer's disease.

scientific article

Baclofen or nNOS inhibitor affect molecular and behavioral alterations evoked by traumatic spinal cord injury in rat spinal cord.

scientific article published on 20 August 2014

Biphasic enhancement of nitric oxide synthase activity and cGMP level following brain ischemia in gerbils

scientific article published on 01 January 1996

Brain ischemia increased high affinity binding of [3H]muscimol into synaptic plasma membrane receptor

scientific article published on 01 January 1990

Brain lipids of a myelin-deficient rabbit mutant during development

scientific article published in June 1986

Ca(2+)-independent, Ca(2+)-dependent, and carbachol-mediated arachidonic acid release from rat brain cortex membrane

scientific article published on October 1991

Carbachol-stimulated release of arachidonic acid and eicosanoids from brain cortex synaptoneurosome lipids of adult and aged rats.

scientific article published in January 1992

Catabolism of mitochondrial membrane phospholipids in conditions of ischemia and barbiturate anesthesia

scientific article published on 01 January 1977

Choline and ethanolamine glycerophospholipid synthesis in isolated synaptosomes of rat brain

scientific article

Cyclic GMP and nitric oxide synthase in aging and Alzheimer's disease.

scientific article published on 09 March 2010

Cyclic GMP metabolism and its role in brain physiology.

scientific article

Detection of protein oxidation in endothelial cells by fluorescently labelled tyramine

scientific article

Diacylglycerol kinase and lipase activities in rat brain subcellular fractions.

scientific article published in January 1986

Differential effect on inositol-phospholipid hydrolysis, cytosolic-free Ca2+ concentration, protein kinase C activity and protein phosphorylation of 1-oleoyl-2-acetyl-sn-glycerol growth-stimulated ascites tumor cells.

scientific article published on August 1988

Docosahexaenoic acid and tetracyclines as promising neuroprotective compounds with poly(ADP-ribose) polymerase inhibitory activities for oxidative/genotoxic stress treatment.

scientific article published on 21 February 2013

Dolichol alters GABA uptake and high affinity binding of agonist to rat brain synaptic plasma membranes

scientific article published in October 1989

Effect of 1-oleoyl-2-acetyl-sn-glycerol on inositol lipid metabolism of ascites tumor cells in culture

scientific article published in May 1989

Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on alpha-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain.

scientific article published in November 2009

Effect of amyloid beta peptide on poly(ADP-ribose) polymerase activity in adult and aged rat hippocampus.

scientific article published in January 2000

Effect of aniracetam on phosphatidylinositol transfer protein alpha in cytosolic and plasma membrane fractions of astrocytes subjected to simulated ischemia in vitro.

scientific article

Effect of anoxia and hypoxia on brain lipid metabolism

scientific article published in June 1980

Effect of atropine and gammahydroxybutyrate on ischemically induced changes in the level of radioactivity in [3H]inositol phosphates in gerbil brain in vivo.

scientific article published in May 1988

Effect of hypoglycemia on the brain free fatty acid level and the uptake of fatty acids by phospholipids

scientific article published on 01 April 1984

Effect of ischemia and hypoxia on rat brain glycolipids.

scientific article published in January 1982

Effect of ischemic anoxia and barbiturate anesthesia on free radical oxidation of mitochondrial phospholipids

scientific article

Effect of poly(ADP-ribose) polymerase inhibitors on oxidative stress evoked hydroxyl radical level and macromolecules oxidation in cell free system of rat brain cortex.

scientific article published in February 2004

Effect of spinal cord compression on cyclic 3',5'-guanosine monophosphate in the white matter columns of rabbit.

scientific article

Effects of acute hypoxia on incorporation of [1-14C]arachidonic into glycerolipids of rat brain

scientific article published on 01 July 1981

Effects of adenine nucleotides, biogenic amines and oleic acid on synthesis of choline and ethanolamine glycerophospholipids in neuronal and glial cells from adult rabbit brain

scientific article published on 01 March 1980

Effects of aging and amyloid-beta peptides on choline acetyltransferase activity in rat brain.

scientific article published in April 2002

Effects of cerebral ischemia on [3H]inositol lipids and [3H]inositol phosphates of gerbil brain and subcellular fractions

scientific article published on 01 March 1987

Effects of free fatty acids on the enzymic synthesis of diacyl and ether types of choline and ethanolamine phosphoglycerides

scientific article published on November 1976

Effects of ischemia and exogenous fatty acids on the energy metabolism in brain mitochondria

scientific article published on 01 January 1972

Effects of postdecapitative ischemia and hypoxia on the phosphoglyceride acyl groups of rat brain membranes

scientific article published on 01 November 1980

Elevated nitric oxide production mediates beta-amyloid-induced mitochondria failure

scientific article published on 01 September 2004

Enzymic synthesis of ethanolamine plasmalogens in the microsomal fraction of rat brain under oxygen deficiency

scientific article published on 01 January 1977

Enzymic synthesis of ether types of choline and ethanolamine phosphoglycerides by microsomal fractions from rat brain and liver

scientific article published on January 1977

Expression and activity of PARP family members in the hippocampus during systemic inflammation: their role in the regulation of prooxidative genes

scientific article

Expression of alpha-synuclein in different brain parts of adult and aged rats

scientific journal article

Fingolimod Affects Transcription of Genes Encoding Enzymes of Ceramide Metabolism in Animal Model of Alzheimer's Disease

scientific article published on 30 April 2020

Glycerophospholipid metabolism regulation in the brain under normal conditions and in anoxia

scientific article published on 01 January 1981

Glycogen synthase kinase 3β and its phosphorylated form (Y216) in the paraquat-induced model of parkinsonism

scientific article published on 9 February 2010

Guanine nucleotides activate cytosolic phospholipase C of ascites tumour cells stimulated by 1-oleoyl-2-acetyl-sn-glycerol

scientific article published on 01 January 1988

Guanine nucleotides and fluoride enhance carbachol-mediated arachidonic acid release from phosphatidylinositol. Evidence for involvement of GTP-binding protein in phospholipase A2 activation

scientific article published on 01 July 1989

Incorporation of linoleic acid into membrane glycerophospholipids from rat brain submitted to ischemia and hypoxia

scientific article published on 01 December 1980

Inhibition of N-methyl-D-aspartic acid-nitric oxide synthase in rat hippocampal slices by ethanol. Evidence for the involvement of tetrahydrobiopterin but not lipid peroxidation

scientific article

Inhibition of Poly(ADP-ribose) Polymerase-1 Enhances Gene Expression of Selected Sirtuins and APP Cleaving Enzymes in Amyloid Beta Cytotoxicity

scientific article published on 12 July 2017

Inhibition of nitric oxide synthase prevents energy failure and oxidative damage evoked in the brain by lipopolysaccharide.

scientific article published in September 2004

Inhibition of poly(ADP-ribose) polymerase-1 alters expression of mitochondria-related genes in PC12 cells: relevance to mitochondrial homeostasis in neurodegenerative disorders

scientific article

Inhibitor of cyclooxygenase-2 protects against amyloid beta peptide-evoked memory impairment in mice

scientific article

Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio

scientific article published on 30 January 2012

Interplay between the p53 tumor suppressor protein family and Cdk5: novel therapeutic approaches for the treatment of neurodegenerative diseases using selective Cdk inhibitors

scientific article published on August 2006

Involvement of multiple protein kinases in cPLA2 phosphorylation, arachidonic acid release, and cell death in in vivo and in vitro models of 1-methyl-4-phenylpyridinium-induced parkinsonism--the possible key role of PKG.

scientific article

Lipid composition of myelin and protein--lipid complex in a neurological rabbit mutant.

scientific article

Lipoxygenases and poly(ADP-ribose) polymerase in amyloid beta cytotoxicity

scientific article published on 2 February 2011

Metabolic disturbances of synaptosomes isolated from ischemic gerbil brain.

scientific article published in May 1985

Metabolic studies on dysmyelinating mutant "pt" rabbit brain in vitro

scientific article

Metabolism of [14C]arachidonic acid-labeled lipids in quiescent and OAG-stimulated ascites tumor cells

scientific article published on 01 September 1992

Metabolism of oleoyl-CoA in rat brain synaptosomes: effects of calcium and post-decapitative ischemia

scientific article published on 01 November 1981

Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease?

scientific article published on October 2007

Modification of GABA and calcium uptake by lipids in synaptosomes from normoxic and ischemic brain

scientific article published in January 1986

Modulation of calcium-dependent neutral protease activity by fatty acids and lysophospholipids

scientific article published on 01 April 1988

Modulatory action of arachidonic acid on GABAA/chloride channel receptor function in adult and aged brain cortex membranes

scientific article published on 01 September 1993

Molecular mechanism of PC12 cell death evoked by sodium nitroprusside, a nitric oxide donor

scientific journal article

Monoacylglycerol lipase. Regulation and increased activity during hypoxia and ischemia

scientific article published on January 1984

NMDA receptor mediated nitric oxide dependent cGMP synthesis in brain cortex and hippocampus. Effect of ischemia on NO related biochemical processes during reperfusion

scientific article published on 01 January 1996

NMDA receptor-dependent nitric oxide and cGMP synthesis in brain hemispheres and cerebellum during reperfusion after transient forebrain ischemia in gerbils: effect of 7-Nitroindazole.

scientific article published in December 1998

Nitric oxide alters arachidonic acid turnover in brain cortex synaptoneurosomes.

scientific article published on 10 October 2005

Nitric oxide responsible for NMDA receptor-evoked inhibition of arachidonic acid incorporation into lipids of brain membrane.

scientific article published in September 1996

Nitric oxide: a potent mediator of glutamatergic neurotoxicity in brain ischemia.

scientific article

Oxydative phosphorylation of mitochondria of Ehrlich ascites tumor cells and normal rat liver in the presence of 2-deoxy-D-glucose

scientific article published on 01 January 1968

P2X7 nucleotide receptor activation enhances IFN gamma-induced type II nitric oxide synthase activity in BV-2 microglial cells

scientific article published on October 2003

Pergolide mesylate, a dopaminergic receptor agonist, applied with L-DOPA enhances serum antioxidant enzyme activity in Parkinson disease.

scientific article published in September 2004

Peroxidation of fatty acids in microsomes prepared from normal and ischemic guinea pig brains

scientific article published on 01 January 1975

Phosphatidylinositol degradation in ischemic brain specifically activated by synaptosomal enzymes

scientific article published on 01 May 1987

Phosphatidylinositol transfer protein expression altered by aging and Parkinson disease.

scientific article published on 16 June 2006

Phospholipid-protein ratio in brain of suckling rabbits treated with an organophosphorus compound

scientific article published on 01 January 1984

Poly(ADP-ribose) metabolism in brain and its role in ischemia pathology

scientific article published on 23 April 2010

Poly(ADP-ribose) polymerase during reperfusion after transient forebrain ischemia: its role in brain edema and cell death

scientific article published in February 2003

Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.

scientific article published on 20 March 2012

Poly(ADP-ribose) polymerase-1 inhibition protects the brain against systemic inflammation.

scientific article published on 9 August 2006

Pramipexole and Fingolimod exert neuroprotection in a mouse model of Parkinson's disease by activation of sphingosine kinase 1 and Akt kinase.

scientific article published on 23 February 2018

Prolonged ischemia differently affects phospholipase C acting against phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate in brain subsynaptosomal fraction

scientific article published on 01 October 1989

Rabbit brain lipids during short-term hyperthermia

scientific article published on June 1986

Recent Insights on the Role of PPAR-β/δ in Neuroinflammation and Neurodegeneration, and Its Potential Target for Therapy

scientific article published on 18 November 2020

Regional differences in the effects of insulin-induced hypoglycemia on phospholipid metabolism of rat brain

scientific article published on 01 January 1984

Regulation of arachidonic acid release by enzyme(s) of rat brain cortex.

scientific article published in January 1990

Regulation of phosphatidylethanolamine degradation by enzyme(s) of subcellular fractions from cerebral cortex.

scientific article published in October 1997

Role of nitric oxide in the brain during lipopolysaccharide-evoked systemic inflammation.

scientific article published in June 2007

Role of phospholipids in calcium accumulation in brain mitochondria from adult rat after ischemic anoxia and hypoxic hypoxia

scientific article published on 01 March 1980

Serotonin 5HT1B/1D receptor agonists abolish NMDA receptor-evoked enhancement of nitric oxide synthase activity and cGMP concentration in brain cortex slices

scientific article published on 01 December 1999

Serotonin, a potent modulator of arachidonic acid turnover, interaction with glutamatergic receptor in brain cortex

scientific article published on 01 August 1994

Serum albumin washing specifically enhances arachidonate incorporation into synaptosomal phosphatidylinositols.

scientific article published in January 1983

Sirtuins and Their Roles in Brain Aging and Neurodegenerative Disorders

scientific article

Sphingosine kinase 1 and sphingosine-1-phosphate in oxidative stress evoked by 1-methyl-4-phenylpyridinium (MPP+) in human dopaminergic neuronal cells

scientific article published on 9 January 2014

Sphingosine kinase 1/sphingosine-1-phosphate receptors dependent signalling in neurodegenerative diseases. The promising target for neuroprotection in Parkinson's disease

scientific article published on 20 June 2018

Sphingosine kinases/sphingosine-1-phosphate and death Signalling in APP-transfected cells

scientific article published on 23 January 2014

Sphingosine-1-phosphate and its effect on glucose deprivation/glucose reload stress: from gene expression to neuronal survival

scientific article

Stimulation of phosphoinositide degradation and phosphatidylinositol-4-phosphate phosphorylation by GTP exclusively in plasma membrane of rat brain

scientific article

Synaptic vesicle-bound phospholipase(s) acting on phosphatidylinositol exhibit(s) high susceptibility to brain ischemia

scientific article published in July 1990

Synthesis in vitro of 1-alkyl-2-acyl- and 1,2-diacyl-sn-glycerophosphorylcholines and ethanolamines by neuronal, glial and synaptosomal fractions from adult rabbit brain

scientific article published on 01 January 1977

Systemic administration of lipopolysaccharide induces molecular and morphological alterations in the hippocampus.

scientific article published on 7 August 2010

The Lipoxygenases: Their Regulation and Implication in Alzheimer's Disease.

scientific article published on 16 December 2015

The Molecular Mechanism of Amyloid β42 Peptide Toxicity: The Role of Sphingosine Kinase-1 and Mitochondrial Sirtuins

scientific article published on 3 September 2015

The Novel Role of PPAR Alpha in the Brain: Promising Target in Therapy of Alzheimer's Disease and Other Neurodegenerative Disorders

scientific article published on 13 March 2020

The effect of selective inhibition of cyclic GMP hydrolyzing phosphodiesterases 2 and 5 on learning and memory processes and nitric oxide synthase activity in brain during aging

scientific article published on 6 April 2008

The effect of transient ischemia on fatty acid and lipid metabolism in the gerbil brain

scientific article published on 01 November 1980

The key role of sphingosine kinases in the molecular mechanism of neuronal cell survival and death in an experimental model of Parkinson's disease.

scientific article published on January 2014

The mechanisms regulating cyclin-dependent kinase 5 in hippocampus during systemic inflammatory response: The effect on inflammatory gene expression.

scientific article published on 21 January 2016

The negative coupling between serotonin and muscarinic receptor(s) for arachidonic acid and inositol phosphates release in brain cortex synaptoneurosomes. Effect of aging.

scientific article

Toxicity of extracellular secreted alpha-synuclein: Its role in nitrosative stress and neurodegeneration

scientific article published on 14 February 2013

Ultrastructural evidence of amyloid beta-induced autophagy in PC12 cells

scientific article published on January 2009

Uptake and subcellular distribution of intraventricularly injected [1-3H]dolichol in rat brain

scientific article

[Effect of ischemia on the free fatty acid content in guinea pig brain]

scientific article published on 01 July 1972

[Influence of NMDA receptor stimulation in brain cortex and hippocampus on NO dependent cGMP synthase. Effect of ischemia on NO related biochemical processes during recirculation]

scientific article published on 01 May 1998

[Mechanisms of brain mitochondrial injury in cerebral ischemia]

scientific article published on 01 September 1980

[The role of cyclooxygenases in neurotoxicity of amyloid beta peptides in Alzheimer's disease].

scientific article published in January 2010

[The role of extracellular α-synuclein in molecular mechanisms of cell death]

scientific article published on 04 November 2013

[The synthesis of plasmalogens during myelination in the rat. VI. The incorporation of 14C,32P-labelled O-(1-alkyl-sn-glycerol-3-phosphoryl) ethanolamine after different incubation times (author's transl)]

scientific article published on 01 July 1973

alpha-Synuclein enhances secretion and toxicity of amyloid beta peptides in PC12 cells.

scientific article published on 29 August 2008