List of works - Eric Le Cam

A key presynaptic role in transformation for a widespread bacterial protein: DprA conveys incoming ssDNA to RecA

scientific journal article

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

scientific article published on 24 September 2012

A three-branched DNA template for carbon nanotube self-assembly into nanodevice configuration.

scientific article published on 12 December 2008

A type IV pilus mediates DNA binding during natural transformation in Streptococcus pneumoniae

scientific article (publication date: 2013)

ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA.

scientific article

Adsorption of DNA to mica mediated by divalent counterions: a theoretical and experimental study.

scientific article published on October 2003

Atomic force microscopy imaging of DNA under macromolecular crowding conditions.

scientific article

C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair

scientific article published on 09 March 2016

Cellular uptake pathways of sepiolite nanofibers and DNA transfection improvement.

scientific article

Conformational changes of DNA minicircles upon the binding of the archaebacterial histone-like protein MC1

scientific article published on 01 March 1995

Constitutive autophagy contributes to resistance to TP53-mediated apoptosis in Epstein-Barr virus-positive latency III B-cell lymphoproliferations.

scientific article published on 13 November 2015

Contribution of DNA conformation and topology in right-handed DNA wrapping by the Bacillus subtilis LrpC protein

scientific article published on 27 November 2002

Effect of Rap1 binding on DNA distortion and potassium permanganate hypersensitivity

scientific article

Extracellular membrane vesicles harbouring viral genomes

scientific article

Functionalization of DNA G-Wires for patterning and nanofabrication.

scientific article

G-quartets direct assembly of HIV-1 nucleocapsid protein along single-stranded DNA.

scientific article

HIV-1 protease and reverse transcriptase control the architecture of their nucleocapsid partner

scientific article (publication date: 2007)

High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes.

scientific article published on 28 March 2007

Histidine containing peptides and polypeptides as nucleic acid vectors.

scientific article

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

scientific article

In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation

scientific article published on 06 September 2019

In vivo and in vitro characterization of DdrC, a DNA damage response protein in Deinococcus radiodurans bacterium

scientific article

Investigation of radiation damage in DNA by using atomic force microscopy.

scientific article published in January 2002

Linker histones incorporation maintains chromatin fiber plasticity

scientific article

Multiple binding of repressed mRNAs by the P-body protein Rck/p54.

scientific article

Multiple topological labeling for imaging single plasmids.

scientific article

Nucleosome chiral transition under positive torsional stress in single chromatin fibers

scientific article published on 01 July 2007

Nucleosome-remodelling machines and other molecular motors observed at the single-molecule level.

scientific article

Observation of binding and polymerization of Fur repressor onto operator-containing DNA with electron and atomic force microscopes

scientific article

Padlock oligonucleotides as a tool for labeling superhelical DNA.

scientific article

Physical interaction of apoptosis-inducing factor with DNA and RNA.

scientific article published in March 2006

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

scientific article

Plasma hydrogenated cationic detonation nanodiamonds efficiently deliver to human cells in culture functional siRNA targeting the Ewing sarcoma junction oncogene

scientific article

Poly-isoprenylated ifosfamide analogs: Preactivated antitumor agents as free formulation or nanoassemblies

scientific article published on 22 May 2017

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

scientific article published on 23 December 2014

Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: An electron microscopy investigation ⬇️

scientific article published on March 1, 1998

Rad51 polymerization reveals a new chromatin remodeling mechanism

scientific article

Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2

scientific article (publication date: 2013)

Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation

scientific article published on 09 July 2018

Recombinases and Related Proteins in the Context of Homologous Recombination Analyzed by Molecular Microscopy

article published in 2018

Sepiolite as a New Nanocarrier for DNA Transfer into Mammalian Cells: Proof of Concept, Issues and Perspectives

scientific article published on 29 December 2017

Simultaneous cathodoluminescence and electron microscopy cytometry of cellular vesicles labeled with fluorescent nanodiamonds

scientific article

Smart DNA vectors based on cyclodextrin polymers: compaction and endosomal release

scientific article published on 17 August 2011

Srs2 removes deadly recombination intermediates independently of its interaction with SUMO-modified PCNA

scientific article published on 25 July 2008

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

scientific article

Study of the DNA/ethidium bromide interactions on mica surface by atomic force microscope: influence of the surface friction.

scientific article

Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase

scientific article published on 01 June 2021

Synthesis of a multibranched porphyrin-oligonucleotide scaffold for the construction of DNA-based nano-architectures.

scientific article

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

scientific article

The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells.

scientific article published on 14 March 2003

The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation

scientific article published on 11 February 2018

Transmission electron microscopy reveals an optimal HIV-1 nucleocapsid aggregation with single-stranded nucleic acids and the mature HIV-1 nucleocapsid protein

scientific article published on 30 August 2006

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint

scientific article

Unique genome replication mechanism of the archaeal virus AFV1.

scientific article published on 23 May 2014

UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli.

scientific article published on 25 November 2004

Verotoxin-1-Induced ER Stress Triggers Apoptotic or Survival Pathways in Burkitt Lymphoma Cells

scientific article published on 11 May 2020

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

scientific article published on 05 October 2018

[Complementarity of microscopies in the structural analysis of DNA minicircles associated to protein MC1]

scientific article published on 01 June 1996

mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes

scientific article published on 22 June 2007

αTAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities.

scientific article

List of works by Eric Le Cam

A key presynaptic role in transformation for a widespread bacterial protein: DprA conveys incoming ssDNA to RecA

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

A three-branched DNA template for carbon nanotube self-assembly into nanodevice configuration.

A type IV pilus mediates DNA binding during natural transformation in Streptococcus pneumoniae

ATP-independent cooperative binding of yeast Isw1a to bare and nucleosomal DNA.

Adsorption of DNA to mica mediated by divalent counterions: a theoretical and experimental study.

Atomic force microscopy imaging of DNA under macromolecular crowding conditions.

C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair

Cellular uptake pathways of sepiolite nanofibers and DNA transfection improvement.

Conformational changes of DNA minicircles upon the binding of the archaebacterial histone-like protein MC1

Constitutive autophagy contributes to resistance to TP53-mediated apoptosis in Epstein-Barr virus-positive latency III B-cell lymphoproliferations.

Contribution of DNA conformation and topology in right-handed DNA wrapping by the Bacillus subtilis LrpC protein

Effect of Rap1 binding on DNA distortion and potassium permanganate hypersensitivity

Extracellular membrane vesicles harbouring viral genomes

Functionalization of DNA G-Wires for patterning and nanofabrication.

G-quartets direct assembly of HIV-1 nucleocapsid protein along single-stranded DNA.

HIV-1 protease and reverse transcriptase control the architecture of their nucleocapsid partner

High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes.

Histidine containing peptides and polypeptides as nucleic acid vectors.

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation

In vivo and in vitro characterization of DdrC, a DNA damage response protein in Deinococcus radiodurans bacterium

Investigation of radiation damage in DNA by using atomic force microscopy.

Linker histones incorporation maintains chromatin fiber plasticity

Multiple binding of repressed mRNAs by the P-body protein Rck/p54.

Multiple topological labeling for imaging single plasmids.

Nucleosome chiral transition under positive torsional stress in single chromatin fibers

Nucleosome-remodelling machines and other molecular motors observed at the single-molecule level.

Observation of binding and polymerization of Fur repressor onto operator-containing DNA with electron and atomic force microscopes

Padlock oligonucleotides as a tool for labeling superhelical DNA.

Physical interaction of apoptosis-inducing factor with DNA and RNA.

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

Plasma hydrogenated cationic detonation nanodiamonds efficiently deliver to human cells in culture functional siRNA targeting the Ewing sarcoma junction oncogene

Poly-isoprenylated ifosfamide analogs: Preactivated antitumor agents as free formulation or nanoassemblies

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

Properties and growth mechanism of the ordered aggregation of a model RNA by the HIV-1 nucleocapsid protein: An electron microscopy investigation ⬇️

Rad51 polymerization reveals a new chromatin remodeling mechanism

Rad52 sumoylation prevents the toxicity of unproductive Rad51 filaments independently of the anti-recombinase Srs2

Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation

Recombinases and Related Proteins in the Context of Homologous Recombination Analyzed by Molecular Microscopy

Sepiolite as a New Nanocarrier for DNA Transfer into Mammalian Cells: Proof of Concept, Issues and Perspectives

Simultaneous cathodoluminescence and electron microscopy cytometry of cellular vesicles labeled with fluorescent nanodiamonds

Smart DNA vectors based on cyclodextrin polymers: compaction and endosomal release

Srs2 removes deadly recombination intermediates independently of its interaction with SUMO-modified PCNA

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

Study of the DNA/ethidium bromide interactions on mica surface by atomic force microscope: influence of the surface friction.

Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase

Synthesis of a multibranched porphyrin-oligonucleotide scaffold for the construction of DNA-based nano-architectures.

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells.

The role of the N-terminal domain of human apurinic/apyrimidinic endonuclease 1, APE1, in DNA glycosylase stimulation

Transmission electron microscopy reveals an optimal HIV-1 nucleocapsid aggregation with single-stranded nucleic acids and the mature HIV-1 nucleocapsid protein

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint

Unique genome replication mechanism of the archaeal virus AFV1.

UvrD helicase, unlike Rep helicase, dismantles RecA nucleoprotein filaments in Escherichia coli.

Verotoxin-1-Induced ER Stress Triggers Apoptotic or Survival Pathways in Burkitt Lymphoma Cells

XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining

[Complementarity of microscopies in the structural analysis of DNA minicircles associated to protein MC1]

mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes

αTAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities.