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List of works by Nozomi Sugimoto

A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo.

scientific article published on 7 May 2015

ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.

scientific article

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

scientific article

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

scientific journal article

Chromatin remodeler sucrose nonfermenting 2 homolog (SNF2H) is recruited onto DNA replication origins through interaction with Cdc10 protein-dependent transcript 1 (Cdt1) and promotes pre-replication complex formation

scientific article published on 20 September 2011

Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.

scientific article published on 11 July 2006

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity

scientific article published on 01 January 2020

GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.

scientific article published on 17 November 2016

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

scientific article published on 03 August 2018

GRWD1, a new player among oncogenesis-related ribosomal/nucleolar proteins.

scientific article

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

scientific article published on 01 July 2018

Heterocomplex formation by Arp4 and β-actin is involved in the integrity of the Brg1 chromatin remodeling complex

scientific article published on 08 May 2012

Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1

scientific article

Molecular Mechanism for Chromatin Regulation During MCM Loading in Mammalian Cells.

scientific article published in January 2017

Nucleosome assembly and disassembly activity of GRWD1, a novel Cdt1-binding protein that promotes pre-replication complex formation

scientific journal article

Redundant and differential regulation of multiple licensing factors ensures prevention of re-replication in normal human cells.

scientific article published in April 2009

TRF2 recruits ORC through TRFH domain dimerization.

scientific article

TRF2-mediated ORC recruitment underlies telomere stability upon DNA replication stress

scientific article published in 2021

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

scientific article

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