List of works - Matti Myllykoski

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

scientific article published on January 2017

Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome)

scientific article published on 03 April 2019

Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases

scientific article published on 05 July 2018

Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility

scientific article

Complex formation between calmodulin and a peptide from the intracellular loop of the gap junction protein connexin43: Molecular conformation and energetics of binding

scientific article published on 07 August 2009

Conformations of peptides derived from myelin-specific proteins in membrane-mimetic conditions probed by synchrotron radiation CD spectroscopy

scientific article published on 20 April 2011

Crystallographic home-source X-ray data for the atomic-resolution experimental phasing of the Shank3 SH3 domain structure from pseudomerohedrally twinned crystals

scientific article published on 18 September 2018

Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase

scientific article

Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath.

scientific article

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

scientific article published on 26 November 2018

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate

scientific article published on 14 March 2019

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

scientific article published on 10 July 2017

Molecular structure and function of myelin protein P0 in membrane stacking

scientific article published in Scientific Reports

Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation ⬇️

scientific article published on February 29, 2012

Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule

scientific journal article

Structural and functional evolution of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

scientific article

Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase

scientific article

Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.

scientific article published on 23 February 2018

Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

scientific article

Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution.

scientific article

Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains

scientific article published on 17 December 2020

List of works by Matti Myllykoski

Antagonistic Functions of MBP and CNP Establish Cytosolic Channels in CNS Myelin

Biallelic loss-of-function P4HTM gene variants cause hypotonia, hypoventilation, intellectual disability, dysautonomia, epilepsy, and eye abnormalities (HIDEA syndrome)

Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases

Collapsin response mediator protein 2: high-resolution crystal structure sheds light on small-molecule binding, post-translational modifications, and conformational flexibility

Complex formation between calmodulin and a peptide from the intracellular loop of the gap junction protein connexin43: Molecular conformation and energetics of binding

Conformations of peptides derived from myelin-specific proteins in membrane-mimetic conditions probed by synchrotron radiation CD spectroscopy

Crystallographic home-source X-ray data for the atomic-resolution experimental phasing of the Shank3 SH3 domain structure from pseudomerohedrally twinned crystals

Determinants of ligand binding and catalytic activity in the myelin enzyme 2',3'-cyclic nucleotide 3'-phosphodiesterase

Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath.

High-affinity heterotetramer formation between the large myelin-associated glycoprotein and the dynein light chain DYNLL1

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate

Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line

Molecular structure and function of myelin protein P0 in membrane stacking

Myelin 2′,3′-Cyclic Nucleotide 3′-Phosphodiesterase: Active-Site Ligand Binding and Molecular Conformation ⬇️

Structural analysis of the complex between calmodulin and full-length myelin basic protein, an intrinsically disordered molecule

Structural and functional evolution of 2',3'-cyclic nucleotide 3'-phosphodiesterase.

Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesterase

Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3.

Structural similarities and functional differences clarify evolutionary relationships between tRNA healing enzymes and the myelin enzyme CNPase

Structure of an unconventional SH3 domain from the postsynaptic density protein Shank3 at ultrahigh resolution.

Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains