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List of works by Thomas C. T. Michaels

Adsorption free energy predicts amyloid protein nucleation rates

scientific article published in 2022

Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.

scientific article

Asymptotic solutions of the Oosawa model for the length distribution of biofilaments

scientific article published in May 2014

Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

scientific article published on 17 April 2020

Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.

scientific article published on 29 May 2018

Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation.

scientific article published on 28 February 2018

Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes

scientific article published on 07 May 2018

Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly.

scientific article published on 28 June 2016

Cooperative Assembly of Hsp70 Subdomain Clusters

scientific article published on 29 May 2018

Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation

scientific article published on 10 August 2020

Direct observation of oligomerization by single molecule fluorescence reveals a multi-step aggregation mechanism for the yeast prion protein Ure2.

scientific article published on 22 January 2018

Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide.

scientific article published on 26 March 2018

Dynamic microfluidic control of supramolecular peptide self-assembly

scientific article

Dynamics of heteromolecular filament formation

scientific article published on November 2016

Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

scientific article published on 13 April 2020

Dynamics of protein aggregation and oligomer formation governed by secondary nucleation

scientific article

Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces.

scientific article published on 11 October 2016

Fluctuations in the Kinetics of Linear Protein Self-Assembly.

scientific article published on 21 June 2016

Force generation by the growth of amyloid aggregates.

scientific article

Hamiltonian Dynamics of Protein Filament Formation

scientific article published on 22 January 2016

Identification of on- and off-pathway oligomers in amyloid fibril formation

scientific article published on 08 June 2020

Kinetic Analysis of Amyloid Formation

scientific article published on 01 January 2018

Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in <i>C. elegans</i>

scientific article published on 8 March 2021

Kinetic constraints on self-assembly into closed supramolecular structures.

scientific article published on 25 September 2017

Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation.

scientific article published on December 2016

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

scientific article

Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading.

scientific article published on 8 April 2018

Mechanical basis for fibrillar bundle morphology

scientific article published on 16 September 2020

Mechanics and kinetics of dynamic instability

scientific article published on 11 May 2020

Molecular mechanisms of protein aggregation from global fitting of kinetic models.

scientific article published on 7 January 2016

Physical determinants of the self-replication of protein fibrils

scientific article published on 18 July 2016

Physical principles of filamentous protein self-assembly kinetics.

scientific article published on 7 February 2017

Quantitative Analysis of Diffusive Reactions at the Solid-Liquid Interface in Finite Systems.

scientific article published on 4 February 2014

Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms

scientific article published on 27 June 2016

Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization.

scientific article published in June 2014

SAR by kinetics for drug discovery in protein misfolding diseases

article published in the Proceedings of the National Academy of Sciences of the United States of America

Scaling theory of electric-field-assisted tunnelling.

scientific article published in July 2014

Secondary nucleation in amyloid formation

scientific article published on 01 August 2018

Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces

scientific article published on 09 August 2018

Spatial control of irreversible protein aggregation

scientific article published on 14 May 2019

Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform

scientific article published on 7 July 2016

The catalytic nature of protein aggregation

scientific article published on 01 January 2020

The length distribution of frangible biofilaments.

scientific article published on October 2015

Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors

scientific article published on 14 September 2020

Thermodynamics of Polypeptide Supramolecular Assembly in the Short-Chain Limit

scientific article published on 10 October 2017

Trodusquemine enhances Aβ aggregation but suppresses its toxicity by displacing oligomers from cell membranes

scientific article published in Nature Communications

β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces.

scientific article published on 3 November 2016