List of works - Sadanandan E Velu

A Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer Cells

scientific article published on 27 July 2019

A facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloids

scientific article

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.

scientific article

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

scientific article

An Expedient Synthesis of Murrayaquinone A via a Novel Oxidative Free Radical Reaction

scientific article published on 04 January 2018

Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

scientific article published on 25 February 2007

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs

scientific article

Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression

scientific article

Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer

scientific article published on 14 August 2018

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

scientific article

Conjugate addition reactions of alpha-aminoalkylcuprates with alpha, beta-alkenyl-, alpha,beta-alkynyl-, alpha,beta-beta,gamma-allenyl-, and alpha,beta-gamma,delta-dienyl carboxylic acid derivatives, nitriles, and sulfoxides

scientific article published on 01 December 2000

Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation

scientific article

Development and validation of an HPLC method for quantitation of BA‐TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice ⬇️

scientific article published on September 15, 2010

Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy

scientific article published on 14 September 2018

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

scientific article published on 3 April 2018

Elevated levels of NO are localized to distal airways in asthma

scientific article

FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

scientific article published on 10 March 2009

Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes

scientific article published on 2 June 2017

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

scientific article

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents.

scientific article published on 14 June 2016

Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.

scientific article published on July 2013

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

scientific article published on May 2009

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases

scientific article published on 30 July 2018

L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.

scientific article

MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53

scientific article published on 07 June 2019

Mini-review: bmx kinase inhibitors for cancer therapy.

scientific article published on September 2013

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.

scientific article published on 8 January 2016

New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.

scientific article published on 8 May 2015

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV

scientific article published on 17 February 2021

Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

scientific article

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

scientific article

SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia

scientific article published on 21 January 2022

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

scientific article

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function

scientific article

Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs.

scientific article

Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors.

scientific article published on 20 May 2010

Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry.

scientific article published on June 2009

Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

scientific article published on 26 October 2020

Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.

scientific article

Tethered dimers as NAD synthetase inhibitors with antibacterial activity.

scientific article

Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.

scientific article published in September 2014

List of works by Sadanandan E Velu

A Novel Marine Natural Product Derived Pyrroloiminoquinone with Potent Activity against Skin Cancer Cells

A facile synthesis of bispyrroloquinone and bispyrroloiminoquinone ring system of marine alkaloids

A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.

A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action.

An Expedient Synthesis of Murrayaquinone A via a Novel Oxidative Free Radical Reaction

Analogs of the marine alkaloid makaluvamines: synthesis, topoisomerase II inhibition, and anticancer activity.

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs

Attenuation of nonsense-mediated mRNA decay enhances in vivo nonsense suppression

Biochemical and Epigenetic Insights into L-2-Hydroxyglutarate, a Potential Therapeutic Target in Renal Cancer

Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

Conjugate addition reactions of alpha-aminoalkylcuprates with alpha, beta-alkenyl-, alpha,beta-alkynyl-, alpha,beta-beta,gamma-allenyl-, and alpha,beta-gamma,delta-dienyl carboxylic acid derivatives, nitriles, and sulfoxides

Cyanobacterial Metabolite Calothrixins: Recent Advances in Synthesis and Biological Evaluation

Development and validation of an HPLC method for quantitation of BA‐TPQ, a novel iminoquinone anticancer agent, and an initial pharmacokinetic study in mice ⬇️

Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy

Discovery and evaluation of nNav1.5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells.

Elevated levels of NO are localized to distal airways in asthma

FBA-TPQ, a novel marine-derived compound as experimental therapy for prostate cancer.

Highly efficient delivery of potent anticancer iminoquinone derivative by multilayer hydrogel cubes

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor

Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents.

Identification of the ZAK-MKK4-JNK-TGFβ signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ.

In vitro and in vivo anticancer activity of novel synthetic makaluvamine analogues.

Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases

L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer.

MDM2-NFAT1 dual inhibitor, MA242: Effective against hepatocellular carcinoma, independent of p53

Mini-review: bmx kinase inhibitors for cancer therapy.

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels.

New small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.

Nonsense-mediated decay controls the reactivation of the oncogenic herpesviruses EBV and KSHV

Preclinical pharmacology of BA-TPQ, a novel synthetic iminoquinone anticancer agent.

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents.

SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function

Synthesis and in vitro anti-lung cancer activity of novel 1, 3, 4, 8-tetrahydropyrrolo [4, 3, 2-de]quinolin-8(1H)-one alkaloid analogs.

Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors.

Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometry.

Synthetic Makaluvamine Analogs Decrease c-Kit Expression and Are Cytotoxic to Neuroendocrine Tumor Cells

Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.

Tethered dimers as NAD synthetase inhibitors with antibacterial activity.

Total Synthesis of Calothrixins A and B via Oxidative Radical Reaction of Cyclohexenone with Aminophenanthridinedione.