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List of works by Frank P Vleggaar

A High Lymph Node Yield is Associated with Prolonged Survival in Elderly Patients Undergoing Curative Gastrectomy for Cancer: A Dutch Population-Based Cohort Study

scientific article

A cyclic AMP response element is involved in retinoic acid-dependent RAR beta 2 promoter activation

scientific article published on December 1992

A new fully covered metal stent with anti-migration features for the treatment of malignant dysphagia

scientific article published on 30 September 2014

A novel lumen-apposing metal stent for endoscopic ultrasound-guided drainage of pancreatic fluid collections: a prospective cohort study

scientific article published on 30 September 2014

A real-time RT-PCR assay for the quantitative determination of adenoviral gene expression in tumor cells.

scientific article published on 21 November 2005

A risk-profiling approach for surveillance of inflammatory bowel disease-colorectal carcinoma is more cost-effective: a comparative cost-effectiveness analysis between international guidelines

scientific article published in August 2014

A rule for determining risk of colorectal cancer in patients with inflammatory bowel disease

scientific article published on 17 July 2014

AI-07GLIOBLASTOMA SUBTYPES DO NOT EXPLOIT DIFFERENTIAL ANGIOGENIC SIGNALING PATHWAYS NOR ARE THE VESSELS FUNCTIONALLY DIFFERENT

Abnormal microsomal detoxification implicated in Fanconi anemia group C by interaction of the FAC protein with NADPH cytochrome P450 reductase

scientific article published on 01 November 1998

Adding preoperative radiotherapy plus cetuximab to perioperative chemotherapy for resectable esophageal adenocarcinoma: a single-center prospective phase II trial

scientific article published on 12 December 2013

Aggregation and cell cycle dependent retinoic acid receptor mRNA expression in P19 embryonal carcinoma cells

scientific article published on February 1, 1992

Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy

scientific article published on 13 April 2010

Apoptosis: target of cancer therapy.

scientific article

Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients.

scientific article published in June 2001

Automated serum peptide profiling using novel magnetic C18 beads off-line coupled to MALDI-TOF-MS

scientific article published on 11 May 2007

BFD-22 a new potential inhibitor of BRAF inhibits the metastasis of B16F10 melanoma cells and simultaneously increased the tumor immunogenicity.

scientific article published on 10 February 2016

Biodegradable stent placement before neoadjuvant chemoradiotherapy as a bridge to surgery in patients with locally advanced esophageal cancer.

scientific article

Bortezomib, but not cisplatin, induces mitochondria-dependent apoptosis accompanied by up-regulation of noxa in the non-small cell lung cancer cell line NCI-H460.

scientific article published on March 2007

CD44, SHH and SOX2 as novel biomarkers in esophageal cancer patients treated with neoadjuvant chemoradiotherapy.

scientific article published on 10 September 2015

CRM1-mediated nuclear export determines the cytoplasmic localization of the antiapoptotic protein Survivin

scientific article published on 01 April 2002

CT-colonography after incomplete colonoscopy: what is the diagnostic yield?

scientific article published in May 2013

Cancer Stem Cells, Epithelial to Mesenchymal Markers, and Circulating Tumor Cells in Small Cell Lung Cancer.

scientific article published on 8 June 2016

Caspase-dependent and -independent suppression of apoptosis by monoHER in Doxorubicin treated cells.

scientific article published on February 2007

Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.

scientific article

Cell death independent of caspases: a review.

scientific article

Challenges in oral drug delivery in patients with esophageal dysphagia

scientific article

Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells

scientific article published on February 2003

Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460.

scientific article

Cholecystectomy without visible scars: the transvaginal method

scientific article published in January 2011

Circulating miRNAs in patients with Barrett's esophagus, high-grade dysplasia and esophageal adenocarcinoma

scientific article published on 01 December 2018

Cisplatin triggers apoptotic or nonapoptotic cell death in Fanconi anemia lymphoblasts in a concentration-dependent manner.

scientific article published on June 2003

Cloning and analysis of the mouse Fanconi anemia group A cDNA and an overlapping penta zinc finger cDNA.

scientific article

Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells.

scientific article

Consistency of a high-grade dysplasia diagnosis in Barrett's oesophagus: a Dutch nationwide cohort study

scientific article published on 30 December 2013

Correspondence re: L. Yang et al., Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine-conjugated Smac peptide. Cancer Res., 63: 831-837, 2003

scientific article published on 01 October 2003

Cryospray ablation using pressurized CO2 for ablation of Barrett's esophagus with early neoplasia: early termination of a prospective series

scientific article

Declining risk of colorectal cancer in inflammatory bowel disease: an updated meta-analysis of population-based cohort studies

scientific article published in March 2013

Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells.

scientific article published on May 2010

Do Fanconi anemia genes control cell response to cross-linking agents by modulating cytochrome P-450 reductase activity?

scientific article

EMT- and MET-related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities.

scientific article published on 28 May 2017

ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation

scientific article published on 18 September 2019

EUS-guided FNA cytology diagnosis of paraduodenal pancreatitis (groove pancreatitis) with numerous giant cells: conservative management allowed by cytological and radiological correlation

scientific article published on 20 March 2014

EUS-guided celiac ganglia neurolysis: a clinical and human cadaver study (with video).

scientific article published on 7 February 2017

EUS-guided drainage of pancreatic fluid collections using a novel lumen-apposing metal stent on an electrocautery-enhanced delivery system: a large retrospective study (with video).

scientific article published on 23 May 2015

EUS-guided gall bladder drainage with a lumen-apposing metal stent: a prospective long-term evaluation

scientific article published on 3 June 2015

Embryological signaling pathways in Barrett's metaplasia development and malignant transformation; mechanisms and therapeutic opportunities.

scientific article

Endoscopic biopsy and EUS for the detection of pathologic complete response after neoadjuvant chemoradiotherapy in esophageal cancer: a systematic review and meta-analysis.

scientific article published on 26 November 2015

Endoscopic corticosteroid injections do not reduce dysphagia after endoscopic dilation therapy in patients with benign esophagogastric anastomotic strictures

scientific article

Endoscopic sclerotherapy for bleeding oesophagogastric varices secondary to extrahepatic portal vein obstruction in an adult Caucasian population

scientific article published on 01 January 1998

Endoscopic ultrasonography-guided drainage is an effective and relatively safe treatment for peripancreatic fluid collections in a cohort of 108 symptomatic patients

scientific article published in August 2013

Endoscopic ultrasound and fine-needle aspiration for the detection of residual nodal disease after neoadjuvant chemoradiotherapy for esophageal cancer

scientific article published on 09 December 2019

Endoscopic ultrasound measurements for detection of residual disease after neoadjuvant chemoradiotherapy for esophageal cancer

scientific article published on 29 November 2018

Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.

scientific article published on January 2006

Erratum to: the ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma

scientific article published on 15 December 2014

Exon 6 skipping in the Fanconi anemia C gene associated with a nonsense/missense mutation (775C-->T) in exon 5: the first example of a nonsense mutation in one exon causing skipping of another downstream

scientific article published on 01 January 1998

Expression and localization of inhibitor of apoptosis proteins in normal human tissues

scientific article published on 17 November 2005

Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA.

scientific article published on November 1996

Expression of X-linked inhibitor of apoptosis as a novel prognostic marker in radically resected non-small cell lung cancer patients

scientific article published on 01 August 2001

Expression of the Fanconi anemia gene FAC in human cell lines: lack of effect of oxygen tension.

scientific article published on January 1995

FANCD2 expression in advanced non-small-cell lung cancer and response to platinum-based chemotherapy.

scientific article published in January 2005

Factors associated with cancer worries in individuals participating in annual pancreatic cancer surveillance

scientific article published on 14 September 2016

Fanconi anemia genes act to suppress a cross-linker-inducible p53-independent apoptosis pathway in lymphoblastoid cell lines.

scientific article published on February 1996

Functional outcome of patients treated for radiation-induced complete esophageal obstruction after successful endoscopic recanalization (with video)

scientific article published on 05 May 2014

GATA6 expression in Barrett's oesophagus and oesophageal adenocarcinoma.

scientific article published on 16 October 2014

Genomic organization of the human retinoic acid receptor beta 2

scientific article (publication date: 30 October 1992)

Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC

scientific article published on 01 March 2008

Global histone modifications predict prognosis of resected non small-cell lung cancer.

scientific article

Growth rate of small pancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: results from an endoscopic ultrasound based cohort study.

scientific article published on 14 December 2016

High frequency of early colorectal cancer in inflammatory bowel disease

scientific article published on 12 March 2008

High lifetime risk of cancer in primary sclerosing cholangitis

scientific article published on 14 October 2008

High prevalence of autoimmune hepatitis among patients with primary sclerosing cholangitis

scientific article published on 01 October 2000

High proximal migration rate of a partially covered "big cup" duodenal stent in patients with malignant gastric outlet obstruction.

scientific article published on 11 December 2013

How to drain the gallbladder: that is the question

scientific article published on 28 January 2020

Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis

scientific article

IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma.

scientific article published on 28 February 2018

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

scientific article published in March 2018

Identification of multiple nuclear export sequences in Fanconi anemia group A protein that contribute to CRM1-dependent nuclear export.

scientific article

Immunohistochemical detection of nuclear survivin in NSCLC: a comparison of commercial antibodies

scientific article published on 01 April 2007

In vitro evaluation of the radial and axial force of self-expanding esophageal stents.

scientific article published on 28 November 2013

Independent root-cause analysis of contributing factors, including dismantling of 2 duodenoscopes, to investigate an outbreak of multidrug-resistant Klebsiella pneumoniae

scientific article published on 15 May 2019

Induction of HOX-2 genes in P19 embryocarcinoma cells is dependent on retinoic acid receptor alpha.

scientific article published on April 1993

International multicenter comprehensive analysis of adverse events associated with lumen-apposing metal stent placement for pancreatic fluid collection drainage

scientific article published on 20 November 2019

Involvement of the Fanconi's anemia protein FAC in a pathway that signals to the cyclin B/cdc2 kinase

scientific article published on 01 June 1997

Kahalalide F induces necrosis-like cell death that involves depletion of ErbB3 and inhibition of Akt signaling.

scientific article

Late activation of apoptotic pathways plays a negligible role in mediating the cytotoxic effects of discodermolide and epothilone B in non-small cell lung cancer cells.

scientific article

Loss of CD44 and SOX2 expression is correlated with a poor prognosis in esophageal adenocarcinoma patients

scientific article published on 16 May 2014

Low value of second-look endoscopy in detecting residual colorectal cancer after endoscopic removal

scientific article published on 24 February 2020

Lung cancer stem cells: origin, features, maintenance mechanisms and therapeutic targeting

scientific article published on 14 December 2018

MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1.

scientific article published on July 2013

MCAM/CD146 promotes tamoxifen resistance in breast cancer cells through induction of epithelial-mesenchymal transition, decreased ERα expression and AKT activation.

scientific article published on 9 November 2016

MRI guided stereotactic radiotherapy for locally advanced pancreatic cancer

scientific article published on 31 July 2018

Management of delayed bleeding after endoscopic mucosal resection of large colorectal polyps: a retrospective multi-center cohort study

scientific article published on 21 July 2020

Metal or plastic stents for preoperative biliary drainage in resectable pancreatic cancer.

scientific article published on 25 August 2015

MiR-221/222 promote epithelial-mesenchymal transition by targeting Notch3 in breast cancer cell lines

scientific article published on 06 August 2018

Microenvironment involved in FPR1 expression by human glioblastomas

scientific article published on 19 April 2015

Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell lines.

scientific article

More right-sided IBD-associated colorectal cancer in patients with primary sclerosing cholangitis.

scientific article published in September 2009

Mouse and human retinoic acid receptor beta 2 promoters: sequence comparison and localization of retinoic acid responsiveness

scientific article (publication date: 1991)

Multiple Interactions Between Cancer Cells and the Tumor Microenvironment Modulate TRAIL Signaling: Implications for TRAIL Receptor Targeted Therapy

scientific article published on 03 July 2019

No reduction of radiation dose following the introduction of dose-area product measurement in endoscopic retrograde cholangiopancreatography

scientific article published on 01 December 2015

Normal expression of the Fanconi anemia proteins FAA and FAC and sensitivity to mitomycin C in two patients with Seckel syndrome.

scientific article published on April 1999

Novel cell death mechanisms of trifluorothymidine.

scientific article published on January 2008

Novel insights into vascularization patterns and angiogenic factors in glioblastoma subclasses

scientific article published on 15 September 2016

Nuclear localization of survivin is a positive prognostic factor for survival in advanced non-small-cell lung cancer

scientific article published on 01 November 2004

Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL.

scientific article published on 17 October 2013

Overview of the clinical problem: facts and current issues of mucinous cystic neoplasms of the pancreas

scientific article published on 22 May 2008

Paclitaxel triggers cell death primarily via caspase-independent routes in the non-small cell lung cancer cell line NCI-H460.

scientific article published on February 2002

Pain patterns in chronic pancreatitis: a nationwide longitudinal cohort study

scientific article published on 06 November 2020

Palliative treatment of malignant dysphagia: stent by and await further instructions

scientific article published in April 2016

Patency of endoscopic ultrasound-guided gastroenterostomy in the treatment of malignant gastric outlet obstruction

scientific article published on 31 August 2020

Patient-reported burden of intensified surveillance and surgery in high-risk individuals under pancreatic cancer surveillance

scientific article published on 19 March 2020

Population-based epidemiology, malignancy risk, and outcome of primary sclerosing cholangitis

scientific article

Prevalence and Progression of Pancreatic Cystic Precursor Lesions Differ Between Groups at High Risk of Developing Pancreatic Cancer

scientific article published on 11 November 2016

Probiotics in primary sclerosing cholangitis: a randomized placebo-controlled crossover pilot study

scientific article

Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancer.

scientific article

Protein replacement by receptor-mediated endocytosis corrects the sensitivity of Fanconi anemia group C cells to mitomycin C.

scientific article published on January 1999

Rapid on-site evaluation during endoscopic ultrasound-guided fine-needle aspiration of lymph nodes does not increase diagnostic yield: A randomized, multicenter trial

scientific article published on 23 April 2018

Removable self-expanding plastic esophageal stent as a continuous, non-permanent dilator in treating refractory benign esophageal strictures: a prospective two-center study

scientific article

Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathwa

scientific article published on June 2003

Retinoic acid resistance of the variant embryonal carcinoma cell line RAC65 is caused by expression of a truncated RAR alpha

scientific article published on January 1, 1992

Robot-assisted Minimally Invasive Thoracolaparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy for Resectable Esophageal Cancer: A Randomized Controlled Trial

article

Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation.

scientific article published on 29 December 2006

Role of endoscopic ultrasonography in the diagnostic work-up of idiopathic acute pancreatitis (PICUS): study protocol for a nationwide prospective cohort study

scientific article published on 20 August 2020

SSTR-2 as a potential tumour-specific marker for fluorescence-guided meningioma surgery

scientific article published on 01 June 2018

Safety and efficacy of the use of lumen-apposing metal stents in the management of postoperative fluid collections: a large, international, multicenter study

scientific article published on 07 June 2019

Sclerosing pancreato-cholangitis responsive to steroid therapy

scientific article published on 01 July 1999

Secreted and tumour targeted human carboxylesterase for activation of irinotecan

scientific article published on September 2002

Sentinel node biopsy during thoracolaparoscopic esophagectomy for advanced esophageal cancer

scientific article published on 19 April 2016

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9

scientific article

Stent placement for benign esophageal leaks, perforations, and fistulae: a clinical prediction rule for successful leakage control

scientific article

Subcellular localization of CrmA: identification of a novel leucine-rich nuclear export signal conserved in anti-apoptotic serpins.

scientific article

Subclassification of newly diagnosed glioblastomas through an immunohistochemical approach.

scientific article

Surveillance of Barrett's esophagus and mortality from esophageal adenocarcinoma: a population-based cohort study

scientific article published in July 2014

Symptoms associated with finding colorectal cancer during colonoscopy

scientific article

Synergistic interaction between trifluorothymidine and docetaxel is sequence dependent.

scientific article published on 18 October 2008

Systematic review: periprocedural hydration in the prevention of post-ERCP pancreatitis

scientific article

TGF-β Antibody Uptake in Recurrent High-Grade Glioma Imaged with 89Zr-Fresolimumab PET.

scientific article

TGF-β as a therapeutic target in high grade gliomas - promises and challenges.

scientific article

TGF-β is an inducer of ZEB1-dependent mesenchymal transdifferentiation in glioblastoma that is associated with tumor invasion.

scientific article published on 2 October 2014

TRAIL and cancer therapy.

scientific article published on 10 March 2008

TRAIL receptor targeting therapies for non-small cell lung cancer: current status and perspectives.

scientific article published on 29 December 2009

TRAIL therapy in non-small cell lung cancer cells: sensitization to death receptor-mediated apoptosis by proteasome inhibitor bortezomib.

scientific article

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

scientific article

Targeting FLIP and Mcl-1 using a combination of aspirin and sorafenib sensitizes colon cancer cells to TRAIL.

scientific article

Targeting apoptosis pathways in lung cancer.

scientific article published on 25 October 2010

The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma.

scientific article published on September 2014

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

scientific article

The Fanconi anemia proteins FAA and FAC function in different cellular compartments to protect against cross-linking agent cytotoxicity

scientific article published on 01 October 1998

The endoplasmic reticulum stress/unfolded protein response in gliomagenesis, tumor progression and as a therapeutic target in glioblastoma.

scientific article published on 19 April 2016

The expression of TUCAN, an inhibitor of apoptosis protein, in patients with advanced non-small cell lung cancer treated with chemotherapy

scientific article published on 01 September 2006

The gene for the precursor of plastocyanin from the cyanobacterium Anabaena sp. PCC 7937: isolation, sequence and regulation

scientific article published on 01 March 1989

The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells.

scientific article published on 18 April 2014

The role of routine preoperative EUS when performed after contrast enhanced CT in the diagnostic work-up in patients suspected of pancreatic or periampullary cancer

scientific article published on 10 January 2014

The safety and efficacy of a new 20-mm lumen apposing metal stent (lams) for the endoscopic treatment of pancreatic and peripancreatic fluid collections: a large international, multicenter study

scientific article published on 22 April 2020

Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors.

scientific article published on 8 March 2011

Toll-like Receptor 2 Signalling and the Lysosomal Machinery in Barrett's Esophagus

scientific article published on September 2016

Toll-like receptor 4 activation in Barrett's esophagus results in a strong increase in COX-2 expression

scientific article published on 17 August 2013

Transcriptional regulation of retinoic acid receptor β in retinoic acid-sensitive and -resistant P19 embryocarcinoma cells ⬇️

scientific article published on March 1, 1991

Treatment for unresectable or metastatic oesophageal cancer: current evidence and trends

scientific article published on 13 December 2017

Treatment of Barrett's esophagus with a novel focal cryoablation device: a safety and feasibility study

scientific article published on 9 July 2015

Treatment of refractory post-esophagectomy anastomotic esophageal strictures using temporary fully covered esophageal metal stenting compared to repeated bougie dilation: results of a randomized controlled trial

Trifluorothymidine induces cell death independently of p53.

scientific article

Tumor Seeding During Colonoscopy as a Possible Cause for Metachronous Colorectal Cancer

scientific article published on 13 August 2019

Two death-inducing human TRAIL receptors to target in cancer: similar or distinct regulation and function?

scientific article

Upper gastrointestinal tumors

scientific article published on 26 February 2014

Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial

scientific article published on 01 July 2020

Well-differentiated Pancreatic Neuroendocrine Tumor in a Patient With Familial Atypical Multiple Mole Melanoma Syndrome (FAMMM)

scientific article published on 01 September 2019

[British and American screening guidelines inadequate for prevention of colorectal carcinoma in patients with inflammatory bowel disease]

scientific article published on 01 December 2007

[Ending up in a wheelchair in a strange way]

scientific article published on 01 February 2010

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