List of works - William Henry Welch, Jr.

A model of the putative pore region of the cardiac ryanodine receptor channel

scientific article

Alcelaphine herpesviruses 1 and 2 SDS-PAGE analysis of virion polypeptides, restriction endonuclease analysis of genomic DNA and virus replication restriction in different cell types

scientific article

Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells

scientific article

An anionic ryanoid, 10-O-succinoylryanodol, provides insights into the mechanisms governing the interaction of ryanoids and the subsequent altered function of ryanodine-receptor channels

scientific article

Antimicrobial peptide RP-1 structure and interactions with anionic versus zwitterionic micelles

scientific article

Binding of captan to DNA polymerase I from Escherichia coli and the concomitant effect on 5'----3' exonuclease activity

scientific article

Calreticulin, a component of the endoplasmic reticulum and of cytotoxic lymphocyte granules, regulates perforin-mediated lysis in the hemolytic model system.

scientific article

Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor.

scientific article published on February 2009

Characterization of a novel microsomal fatty acid synthetase (FAS) compared to a cytosolic FAS in the housefly, Musca domestica.

scientific article published in October 1997

Chemical cross-linking stabilizes the enzymic activity and quaternary structure of formyltetrahydrofolate synthetase

scientific article published on 01 November 1980

Comparative Arrhenius plots of enzyme activity from penicillium ⬇️

scientific article published on 01 July 1973

Concentrations of caffeine greater than 20 mM increase the indo-1 fluorescence ratio in a Ca(2+)-independent manner

scientific article

De novo molecular modeling and biophysical characterization of Manduca sexta eclosion hormone

scientific article published on September 2009

Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel

scientific article

Erratum to: Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities.

scientific article published in March 2014

Excess noise in modified conductance states following the interaction of ryanoids with cardiac ryanodine receptor channels

scientific article published in April 2002

Functional and structural diversity in the Als protein family of Candida albicans

scientific article

Functional expression of a bark beetle cytochrome P450 that hydroxylates myrcene to ipsdienol

scientific article

His-404 and His-405 are essential for enzyme catalytic activities of a bacterial indole-3-acetyl-L-aspartic acid hydrolase

scientific article published in September 2004

Hydrogen-tritium exchange in polypeptides. Models of alpha-helical and beta conformations

scientific article published on 01 June 1974

IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis

scientific article

Ipsdienol dehydrogenase (IDOLDH): a novel oxidoreductase important for Ips pini pheromone production

scientific article

Isolation and characterization of farnesyl diphosphate synthase from the cotton boll weevil, Anthonomus grandis

scientific article published in June 2009

Isolation and functional expression of an animal geranyl diphosphate synthase and its role in bark beetle pheromone biosynthesis

scientific article

Juvenile hormone diol kinase. I. Purification, characterization, and substrate specificity of juvenile hormone-selective diol kinase from Manduca sexta

scientific article published on 21 March 2002

Juvenile hormone diol kinase. II. Sequencing, cloning, and molecular modeling of juvenile hormone-selective diol kinase from Manduca sexta

scientific article

Kinetic analysis of the amplification phase for activation and binding of C3 to encapsulated and nonencapsulated Cryptococcus neoformans ⬇️

scientific article published on August 1, 1992

Modular determinants of antimicrobial activity in platelet factor-4 family kinocidins

scientific article

Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities

scientific article

Monovalent cation induced reassociation of formyltetrahydrofolate synthetase monitored by Rayleigh light scattering and enzymic activity.

scientific article published in July 1982

Myrcene hydroxylases do not determine enantiomeric composition of pheromonal ipsdienol in Ips spp.

scientific article published on 26 November 2008

Observations on the monovalent cation requirements of formyltetrahydrofolate synthetase

scientific article published on 01 February 1968

Phosphatidylethanolamine N-methyltransferase in human red blood cell membrane preparations. Kinetic mechanism

scientific article published in Journal of Biological Chemistry

Phospholipid methylation in brain membrane preparations: kinetic mechanism

scientific article published in February 1993

Platelet microbicidal protein 1: structural themes of a multifunctional antimicrobial peptide

scientific article published in November 2004

Promiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviour

scientific article published in Scientific Reports

Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule

scientific article

Protein-polysaccharide interactions. A monoclonal antibody specific for the capsular polysaccharide of Cryptococcus neoformans

scientific article published in January 1994

Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid

scientific article published on 01 May 2007

Quantitative relationships between ryanoids, receptor affinity and channel conductance

scientific article

Residue Gln4863 within a predicted transmembrane sequence of the Ca2+ release channel (ryanodine receptor) is critical for ryanodine interaction

scientific article published on 13 October 2003

Ryanoid modification of the cardiac muscle ryanodine receptor channel results in relocation of the tetraethylammonium binding site

scientific article

Stereo-selective binding of monoclonal antibodies to the poly-γ-D-glutamic acid capsular antigen of Bacillus anthracis

scientific article published on 17 April 2013

Structural basis of the phospholipid acyltransferase enzyme substrate specificity: a computer modeling study of the phospholipid acceptor molecule

scientific article published on 01 March 1995

Structural characteristics that govern binding to, and modulation through, the cardiac ryanodine receptor nucleotide binding site

scientific article

Structural components of ryanodine responsible for modulation of sarcoplasmic reticulum calcium channel function

scientific article published on 01 March 1997

Structural correlates of antimicrobial efficacy in IL-8 and related human kinocidins

scientific article published on 30 November 2006

Structural determinants of high-affinity binding of ryanoids to the vertebrate skeletal muscle ryanodine receptor: a comparative molecular field analysis

scientific article published on 01 May 1994

Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor

scientific article

Substrate specificity and kinetics for VP14, a carotenoid cleavage dioxygenase in the ABA biosynthetic pathway

scientific article

Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues

scientific article published on February 2006

The Gln4863Ala mutation within a putative, pore-lining trans-membrane helix of the cardiac ryanodine receptor channel alters both the kinetics of ryanoid interaction and the subsequent fractional conductance

scientific article published on 14 June 2005

The interaction of a neutral ryanoid with the ryanodine receptor channel provides insights into the mechanisms by which ryanoid binding is modulated by voltage

scientific article

The interaction of an impermeant cation with the sheep cardiac RyR channel alters ryanoid association

scientific article published on 15 March 2006

The pharmacology of ryanodine and related compounds.

scientific article published on March 1997

The pyrrole locus is the major orienting factor in ryanodine binding

scientific article published on 01 June 1996

The stimulation of rat brain monoamine oxidase by dietary lithium chloride ⬇️

scientific article published on August 15, 1979

The subunit structure of formyltetrahydrofolate synthetase

scientific article published on 01 June 1971

Voltage-sensitive equilibrium between two states within a ryanoid-modified conductance state of the ryanodine receptor channel

scientific article

pKa and aggregation of bilirubin: titrimetric and ultracentrifugation studies on water-soluble pegylated conjugates of bilirubin and fatty acids

scientific article

List of works by William Henry Welch, Jr.

A model of the putative pore region of the cardiac ryanodine receptor channel

Alcelaphine herpesviruses 1 and 2 SDS-PAGE analysis of virion polypeptides, restriction endonuclease analysis of genomic DNA and virus replication restriction in different cell types

Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells

An anionic ryanoid, 10-O-succinoylryanodol, provides insights into the mechanisms governing the interaction of ryanoids and the subsequent altered function of ryanodine-receptor channels

Antimicrobial peptide RP-1 structure and interactions with anionic versus zwitterionic micelles

Binding of captan to DNA polymerase I from Escherichia coli and the concomitant effect on 5'----3' exonuclease activity

Calreticulin, a component of the endoplasmic reticulum and of cytotoxic lymphocyte granules, regulates perforin-mediated lysis in the hemolytic model system.

Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor.

Characterization of a novel microsomal fatty acid synthetase (FAS) compared to a cytosolic FAS in the housefly, Musca domestica.

Chemical cross-linking stabilizes the enzymic activity and quaternary structure of formyltetrahydrofolate synthetase

Comparative Arrhenius plots of enzyme activity from penicillium ⬇️

Concentrations of caffeine greater than 20 mM increase the indo-1 fluorescence ratio in a Ca(2+)-independent manner

De novo molecular modeling and biophysical characterization of Manduca sexta eclosion hormone

Electrophysiological effects of ryanodine derivatives on the sheep cardiac sarcoplasmic reticulum calcium-release channel

Erratum to: Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities.

Excess noise in modified conductance states following the interaction of ryanoids with cardiac ryanodine receptor channels

Functional and structural diversity in the Als protein family of Candida albicans

Functional expression of a bark beetle cytochrome P450 that hydroxylates myrcene to ipsdienol

His-404 and His-405 are essential for enzyme catalytic activities of a bacterial indole-3-acetyl-L-aspartic acid hydrolase

Hydrogen-tritium exchange in polypeptides. Models of alpha-helical and beta conformations

IgG subclass and heavy chain domains contribute to binding and protection by mAbs to the poly γ-D-glutamic acid capsular antigen of Bacillus anthracis

Ipsdienol dehydrogenase (IDOLDH): a novel oxidoreductase important for Ips pini pheromone production

Isolation and characterization of farnesyl diphosphate synthase from the cotton boll weevil, Anthonomus grandis

Isolation and functional expression of an animal geranyl diphosphate synthase and its role in bark beetle pheromone biosynthesis

Juvenile hormone diol kinase. I. Purification, characterization, and substrate specificity of juvenile hormone-selective diol kinase from Manduca sexta

Juvenile hormone diol kinase. II. Sequencing, cloning, and molecular modeling of juvenile hormone-selective diol kinase from Manduca sexta

Kinetic analysis of the amplification phase for activation and binding of C3 to encapsulated and nonencapsulated Cryptococcus neoformans ⬇️

Modular determinants of antimicrobial activity in platelet factor-4 family kinocidins

Molecular models of the Mojave rattlesnake (Crotalus scutulatus scutulatus) venom metalloproteinases reveal a structural basis for differences in hemorrhagic activities

Monovalent cation induced reassociation of formyltetrahydrofolate synthetase monitored by Rayleigh light scattering and enzymic activity.

Myrcene hydroxylases do not determine enantiomeric composition of pheromonal ipsdienol in Ips spp.

Observations on the monovalent cation requirements of formyltetrahydrofolate synthetase

Phosphatidylethanolamine N-methyltransferase in human red blood cell membrane preparations. Kinetic mechanism

Phospholipid methylation in brain membrane preparations: kinetic mechanism

Platelet microbicidal protein 1: structural themes of a multifunctional antimicrobial peptide

Promiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviour

Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule

Protein-polysaccharide interactions. A monoclonal antibody specific for the capsular polysaccharide of Cryptococcus neoformans

Quantification of the effects of a ryanodine receptor channel mutation on interaction with a ryanoid

Quantitative relationships between ryanoids, receptor affinity and channel conductance

Residue Gln4863 within a predicted transmembrane sequence of the Ca2+ release channel (ryanodine receptor) is critical for ryanodine interaction

Ryanoid modification of the cardiac muscle ryanodine receptor channel results in relocation of the tetraethylammonium binding site

Stereo-selective binding of monoclonal antibodies to the poly-γ-D-glutamic acid capsular antigen of Bacillus anthracis

Structural basis of the phospholipid acyltransferase enzyme substrate specificity: a computer modeling study of the phospholipid acceptor molecule

Structural characteristics that govern binding to, and modulation through, the cardiac ryanodine receptor nucleotide binding site

Structural components of ryanodine responsible for modulation of sarcoplasmic reticulum calcium channel function

Structural correlates of antimicrobial efficacy in IL-8 and related human kinocidins

Structural determinants of high-affinity binding of ryanoids to the vertebrate skeletal muscle ryanodine receptor: a comparative molecular field analysis

Structural factors that determine the ability of adenosine and related compounds to activate the cardiac ryanodine receptor

Substrate specificity and kinetics for VP14, a carotenoid cleavage dioxygenase in the ABA biosynthetic pathway

Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues

The Gln4863Ala mutation within a putative, pore-lining trans-membrane helix of the cardiac ryanodine receptor channel alters both the kinetics of ryanoid interaction and the subsequent fractional conductance

The interaction of a neutral ryanoid with the ryanodine receptor channel provides insights into the mechanisms by which ryanoid binding is modulated by voltage

The interaction of an impermeant cation with the sheep cardiac RyR channel alters ryanoid association

The pharmacology of ryanodine and related compounds.

The pyrrole locus is the major orienting factor in ryanodine binding

The stimulation of rat brain monoamine oxidase by dietary lithium chloride ⬇️

The subunit structure of formyltetrahydrofolate synthetase

Voltage-sensitive equilibrium between two states within a ryanoid-modified conductance state of the ryanodine receptor channel

pKa and aggregation of bilirubin: titrimetric and ultracentrifugation studies on water-soluble pegylated conjugates of bilirubin and fatty acids