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List of works by Isabel Goncalves

A biomarker of collagen type I degradation is associated with cardiovascular events and mortality in patients with atherosclerosis

scientific article published on 28 August 2018

ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis.

scientific article

Activation of calpain-1 in human carotid artery atherosclerotic lesions

scientific article published on 18 June 2009

Activation of immune responses against the basement membrane component collagen type IV does not affect the development of atherosclerosis in ApoE-deficient mice

article

Activator protein-1 in carotid plaques is related to cerebrovascular symptoms and cholesteryl ester content

scientific article published on 01 January 2011

Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques.

scientific article published on 19 March 2018

Apolipoprotein B-100 Antibody Interaction With Atherosclerotic Plaque Inflammation and Repair Processes

scientific article published on 10 March 2016

Association between renin and atherosclerotic burden in subjects with and without type 2 diabetes.

scientific article

Associations Between Macrophage Colony-Stimulating Factor and Monocyte Chemotactic Protein 1 in Plasma and First-Time Coronary Events: A Nested Case-Control Study

scientific article published on 13 September 2016

Attenuation of experimental atherosclerosis by interleukin-19.

scientific article published on 15 August 2013

Cardiovascular organ damage in type 2 diabetes mellitus: the role of lipids and inflammation

scientific article published on 10 May 2019

Cartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques

scientific article published on 09 September 2019

Changes related to age and cerebrovascular symptoms in the extracellular matrix of human carotid plaques

scientific article published on 13 February 2003

Changing From Conventional to Eversion Endarterectomy in Carotid Artery Disease—A Safe Transition Process in the Short and Long Term ⬇️

scientific article published on July 30, 2010

Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques

scientific article published on 3 June 2015

Collagen and related extracellular matrix proteins in atherosclerotic plaque development.

scientific article

Computer-assisted carotid plaque analysis: characteristics of plaques associated with cerebrovascular symptoms and cerebral infarction.

scientific article published in February 2000

Coronary liposuction during percutaneous coronary intervention: evidence by near-infrared spectroscopy that aspiration reduces culprit lesion lipid content prior to stent placement.

scientific article published on 28 September 2014

Decreased levels of stem cell factor in subjects with incident coronary events.

scientific article published on 14 October 2015

Detecting the vulnerable plaque in patients

scientific article published on 26 August 2015

Determining carotid plaque vulnerability using ultrasound center frequency shifts

scientific article published on 15 January 2016

Direct association between diet and the stability of human atherosclerotic plaque.

scientific article

Distinctive peri-luminal presence of agrin in murine and human carotid atherosclerotic plaques

scientific article published on 6 February 2018

Dystrophin deficiency reduces atherosclerotic plaque development in ApoE-null mice

scientific article

Echolucency of carotid plaques correlates with plaque cellularity

scientific article published on 01 July 2003

Effects of simvastatin on circulating autoantibodies to oxidized LDL antigens: relation with immune stimulation markers.

scientific article published in March 2009

Elastin- and collagen-rich human carotid plaques have increased levels of the cysteine protease inhibitor cystatin C.

scientific article published on 28 March 2008

Elevated IL-27 in patients with acute coronary syndrome is associated with adverse ventricular remodeling and increased risk of recurrent myocardial infarction and cardiovascular death.

scientific article published on 7 February 2018

Elevated Markers of Death Receptor-Activated Apoptosis are Associated with Increased Risk for Development of Diabetes and Cardiovascular Disease.

scientific article published on 24 November 2017

Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes

scientific article published on 07 May 2015

Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up.

scientific article published on 22 June 2016

Evidence Supporting a Key Role of Lp-PLA2-Generated Lysophosphatidylcholine in Human Atherosclerotic Plaque Inflammation

article

Evidence for a protective role of placental growth factor in cardiovascular disease

scientific article published on 01 December 2020

Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients

scientific article published on 06 September 2014

Exploring the role of extracellular matrix proteins to develop biomarkers of plaque vulnerability and outcome

scientific article published on 03 February 2020

Expression of fibromodulin in carotid atherosclerotic plaques is associated with diabetes and cerebrovascular events.

scientific article published on 18 June 2015

Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

scientific article published on 22 September 2015

High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy

scientific article

High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

scientific article published on 27 January 2016

High plasma levels of heparin-binding epidermal growth factor are associated with a more stable plaque phenotype and reduced incidence of coronary events

scientific article published on 30 October 2014

Human Carotid Plaques With High Levels of Interleukin-16 Are Associated With Reduced Risk for Cardiovascular Events

scientific article published on September 2015

Humoral immune response against defined oxidized low-density lipoprotein antigens reflects structure and disease activity of carotid plaques

scientific article published on 14 April 2005

Identification of the target for therapeutic recombinant anti-apoB-100 peptide antibodies in human atherosclerotic lesions

scientific article published on 30 November 2008

Impaired fibrous repair: a possible contributor to atherosclerotic plaque vulnerability in patients with type II diabetes

scientific article published on 17 July 2014

Increased aldehyde-modification of collagen type IV in symptomatic plaques--a possible cause of endothelial dysfunction.

scientific article published on 24 February 2015

Increased echolucency of carotid plaques in patients with type 2 diabetes

scientific article published on 24 May 2007

Increased proteolytic cleavage of osteoglycin is associated with a stable plaque phenotype and lower risk of cardiovascular events

scientific article published in 2022

Inhibition of pro-inflammatory myeloid cell responses by short-term S100A9 blockade improves cardiac function after myocardial infarction

scientific article published on 01 August 2019

Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

scientific article published on 11 July 2017

Legumain is upregulated in acute cardiovascular events and associated with improved outcome - potentially related to anti-inflammatory effects on macrophages

scientific article published on 14 December 2019

Long-term treatment with low-dose metoprolol CR/XL is associated with increased plaque echogenicity: the Beta-blocker Cholesterol-lowering Asymptomatic Plaque Study (BCAPS)

scientific article published on 19 January 2011

Low carotid calcium score is associated with higher levels of glycosaminoglycans, tumor necrosis factor-alpha, and parathyroid hormone in human carotid plaques

scientific article published on 11 August 2011

Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke

scientific article

Low levels of IgG autoantibodies against the apolipoprotein B antigen p210 increases the risk of cardiovascular death after carotid endarterectomy.

scientific article published on 28 January 2015

Markers of Basement Membrane Remodeling Are Associated With Higher Mortality in Patients With Known Atherosclerosis

scientific article published on 01 November 2018

Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: a European cross-sectional study

article

Metformin is the key factor in elevated plasma growth differentiation factor-15 levels in type 2 diabetes: A nested, case-control study

scientific article published on 02 October 2018

NFAT regulates the expression of AIF-1 and IRT-1: yin and yang splice variants of neointima formation and atherosclerosis

scientific article

Plasma levels of high-sensitive C-reactive protein do not correlate with inflammatory activity in carotid atherosclerotic plaques.

scientific article

Plasma stem cell factor levels are associated with risk of cardiovascular disease and death.

scientific article published on 26 August 2017

Serology assessment of antibody response to SARS-CoV-2 in patients with COVID-19 by rapid IgM/IgG antibody test

scientific article published on 20 September 2020

Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation

scientific article published on 07 April 2016

Spotty Carotid Plaques Are Associated with Inflammation and the Occurrence of Cerebrovascular Symptoms.

scientific article published on 15 January 2018

Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy

scientific article published on 29 July 2019

The conundrum of asymptomatic carotid stenosis-determinants of decision and evidence

scientific article published on 01 October 2020

The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death

scientific article published on 25 September 2020

The soluble receptor for advanced glycation end-products (sRAGE) has a dual phase-dependent association with residual cardiovascular risk after an acute coronary event

scientific article published on 24 May 2019

Transthyretin expression in the postischemic brain

scientific article published on 03 September 2019

Treatment with betablockers is associated with higher grey-scale median in carotid plaques

scientific article

Use of Vascular Assessments and Novel Biomarkers to Predict Cardiovascular Events in Type 2 Diabetes: The SUMMIT VIP Study

scientific article published on 30 July 2018

sTRAIL-R2 (Soluble TNF [Tumor Necrosis Factor]-Related Apoptosis-Inducing Ligand Receptor 2) a Marker of Plaque Cell Apoptosis and Cardiovascular Events

scientific article published on 05 July 2019

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