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List of works by Oliver Friedrich

'Set the controls...' - phenotype matching beyond genetics in muscular dystrophy

scientific article published on 01 April 2014

3D Printed Lab-on-a-Chip Platform for Chemical Stimulation and Parallel Analysis of Ion Channel Function

scientific article published on 19 August 2019

3D printed oxidized alginate-gelatin bioink provides guidance for C2C12 muscle precursor cell orientation and differentiation via shear stress during bioprinting

scientific article published on 02 June 2020

: 2D Inplane Cell Stretch Systems for Studies of Cardiac Mechano-Signaling

scientific article published on 27 March 2019

A Novel Bone Substitute with High Bioactivity, Strength, and Porosity for Repairing Large and Load-Bearing Bone Defects

scientific article published on 18 February 2019

A Recombinant Human Pluripotent Stem Cell Line Stably Expressing Halide-Sensitive YFP-I152L for GABAAR and GlyR-Targeted High-Throughput Drug Screening and Toxicity Testing

scientific article

A novel quantitative morphometry approach to assess regeneration in dystrophic skeletal muscle

scientific article published on 04 May 2014

A portable low-cost long-term live-cell imaging platform for biomedical research and education.

scientific article

Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin

scientific article published on 24 May 2018

Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling

scientific article

Altered Ca2+ kinetics associated with α-actinin-3 deficiency may explain positive selection for ACTN3 null allele in human evolution

scientific article

Artemisinin-(Iso)quinoline Hybrids by C-H Activation and Click Chemistry: Combating Multidrug-Resistant Malaria

scientific article published on 08 August 2019

Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria

scientific article published in 2019

Assessing viability of extracorporeal preserved muscle transplants using external field stimulation: a novel tool to improve methods prolonging bridge-to-transplantation time

scientific article published on 6 July 2015

Assessment of Plasmodium falciparum PfMDR1 transport rates using Fluo-4.

scientific article

Assessment of Population and ECM Production Using Multiphoton Microscopy as an Indicator of Cell Viability.

scientific article published in January 2017

Automated multiscale morphometry of muscle disease from second harmonic generation microscopy using tensor-based image processing.

scientific article published on 8 September 2011

Bacterial nanocellulose stimulates mesenchymal stem cell expansion and formation of stable collagen-I networks as a novel biomaterial in tissue engineering.

scientific article

Beyond endoscopic assessment in inflammatory bowel disease: real-time histology of disease activity by non-linear multimodal imaging

scientific article published on 13 July 2016

Calcium Sensitive Fluorescent Dyes Fluo-4 and Fura Red under Pressure: Behaviour of Fluorescence and Buffer Properties under Hydrostatic Pressures up to 200 MPa

scientific article

Calcium currents during contraction and shortening in enzymatically isolated murine skeletal muscle fibres

scientific article published on 01 June 1999

Chloroquine exposure triggers distinct cellular responses in sensitive versus resistant Plasmodium falciparum parasites

scientific article published in Scientific Reports

Critical Illness Myopathy (CIM) and Ventilator-Induced Diaphragm Muscle Dysfunction (VIDD): Acquired Myopathies Affecting Contractile Proteins.

scientific article published on 6 December 2016

Critical illness myopathy: sepsis-mediated failure of the peripheral nervous system.

scientific article published on January 2008

Critical illness myopathy: what is happening?

scientific article (publication date: July 2006)

Deeper Insight into the Six-Step Domino Reaction of Aldehydes with Malononitrile and Evaluation of Antiviral and Antimalarial Activities of the Obtained Bicyclic Products.

scientific article published on 26 April 2017

Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.

scientific article published on 4 February 2008

Depolarisation of the plasma membrane in the arsenic trioxide (As2O3)-and anti-CD95-induced apoptosis in myeloid cells.

scientific article published in December 2004

Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice

scientific article published on 3 May 2017

Effects of Material-Tissue Interactions on Bone Regeneration Outcomes Using Baghdadite Implants in a Large Animal Model

scientific article published on 06 June 2018

Electrophysiological investigations of peripheral nerves and muscles: a method for looking at cell dysfunction in the critically ill patients

scientific article published on 29 January 2019

Elementary Ca2+ release events in mammalian skeletal muscle: effects of the anaesthetic drug thiopental.

scientific article published on 4 August 2006

Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk

scientific article published on 30 October 2017

Enhanced muscle shortening and impaired Ca2+ channel function in an acute septic myopathy model.

scientific article published on 4 November 2009

Fast XYT imaging of elementary calcium release events in muscle with multifocal multiphoton microscopy and wavelet denoising and detection.

scientific article published in July 2007

From chaos to split-ups--SHG microscopy reveals a specific remodelling mechanism in ageing dystrophic muscle.

scientific article published on February 2013

GABAmimetic intravenous anaesthetics inhibit spontaneous Ca2+ -oscillations in cultured hippocampal neurons.

scientific article published in July 2006

Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

scientific article published on 22 June 2006

Growing Old Too Early: Skeletal Muscle Single Fiber Biomechanics in Ageing R349P Desmin Knock-in Mice Using the MyoRobot Technology

scientific article published on 31 July 2020

Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities

scientific article published on 29 July 2015

Hybrid integration of scalable mechanical and magnetophoretic focusing for magnetic flow cytometry.

scientific article published on 12 March 2018

Hydroxyethyl starch solution for extracorporeal tissue perfusion.

scientific article published on 17 February 2016

IL-1α reversibly inhibits skeletal muscle ryanodine receptor. a novel mechanism for critical illness myopathy?

scientific article

Improving alginate printability for biofabrication: establishment of a universal and homogeneous pre-crosslinking technique

scientific article published on 02 June 2020

In mammalian skeletal muscle, phosphorylation of TOMM22 by protein kinase CSNK2/CK2 controls mitophagy.

scientific article published on 22 November 2017

Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation

scientific article published on 16 November 2018

Innenrücktitelbild: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. 37/2019)

scientific article published in 2019

Inside Back Cover: Artemisinin–(Iso)quinoline Hybrids by C−H Activation and Click Chemistry: Combating Multidrug‐Resistant Malaria (Angew. Chem. Int. Ed. 37/2019)

scientific article published in 2019

Ketamine stereoselectively inhibits spontaneous Ca2+-oscillations in cultured hippocampal neurons.

scientific article published in June 2005

Label-Free High-Throughput Leukemia Detection by Holographic Microscopy

scientific article published on 11 October 2018

Label-Free Multiphoton Endomicroscopy for Minimally Invasive In Vivo Imaging

scientific article published on 25 February 2019

Label-free imaging of inflammatory bowel disease using multiphoton microscopy.

scientific article published on 11 July 2013

Label-free, high-throughput detection of P. falciparum infection in sphered erythrocytes with digital holographic microscopy

scientific article published on 01 June 2018

Long-term NMDA receptor inhibition affects NMDA receptor expression and alters glutamatergic activity in developing rat hippocampal neurons

scientific article published on 30 April 2015

Magnetic Tissue Engineering of the Vocal Fold Using Superparamagnetic Iron Oxide Nanoparticles

scientific article published on 02 May 2019

Magnetic fingerprints of rolling cells for quantitative flow cytometry in whole blood

scientific article

Mechanical properties of cell- and microgel bead-laden oxidized alginate-gelatin hydrogels

Mechano-regulation of the beating heart at the cellular level – Mechanosensitive channels in normal and diseased heart ⬇️

scientific article published on August 27, 2012

Membrane ion conductances of mammalian skeletal muscle in the post-decompression state after high-pressure treatment.

scientific article

Mini-dystrophin restores L-type calcium currents in skeletal muscle of transgenic mdx mice.

scientific article published on 31 October 2003

Motor protein function in skeletal abdominal muscle of cachectic cancer patients

scientific article

Motor protein function in skeletal muscle-a multiple scale approach to contractility.

scientific article published on 30 June 2009

Multiphoton Microscopy Reveals DAPK1-Dependent Extracellular Matrix Remodeling in a Chorioallantoic Membrane (CAM) Model

scientific article published on 10 May 2022

Multiphoton microscopy analysis of extracellular collagen I network formation by mesenchymal stem cells.

scientific article published on 29 December 2015

MyoBio: An Automated Bioreactor System Technology for Standardized Perfusion-Decellularization of Whole Skeletal Muscle

scientific article published in 2022

MyoRobot 2.0: An advanced biomechatronics platform for automated, environmentally controlled skeletal muscle single fiber biomechanics assessment employing inbuilt real-time optical imaging

scientific article published on 12 May 2019

NA+- and K+-channels as molecular targets of the alkaloid ajmaline in skeletal muscle fibres

scientific article published on 12 March 2007

Nano- and Micro-Patterned S-, H-, and X-PDMS for Cell-Based Applications: Comparison of Wettability, Roughness, and Cell-Derived Parameters.

scientific article

New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids

scientific article published on 28 April 2015

New factors contributing to dynamic calcium regulation in the skeletal muscle triad-a crowded place

scientific article

One arm is enough, two might actually be worse--when dystrophic muscle cells grow old

scientific article published on 22 February 2010

Optical prediction of single muscle fiber force production using a combined biomechatronics and second harmonic generation imaging approach

scientific article published on 24 October 2018

Optimizing neuronal differentiation of human pluripotent NT2 stem cells in monolayer cultures.

scientific article

Performance of scientific cameras with different sensor types in measuring dynamic processes in fluorescence microscopy

scientific article published on 3 June 2013

PiezoGRIN: A High-Pressure Chamber Incorporating GRIN Lenses for High-Resolution 3D-Microscopy of living Cells and Tissues

scientific article published on 14 December 2018

Portoporator©: A portable low-cost electroporation device for gene transfer to cultured cells in biotechnology, biomedical research and education

scientific article published on 19 February 2019

Preaged remodeling of myofibrillar cytoarchitecture in skeletal muscle expressing R349P mutant desmin.

scientific article published on 13 June 2017

Pressure, the nervous system and ion channels: are humans too complicated?

scientific article published in September 2010

Proliferation characteristics of cells cultured under periodic versus static conditions

scientific article published on 04 December 2018

Quantification of human complement factor H binding to asexual malaria blood stages by an enzyme-linked immunosorbent assay.

scientific article published on 12 February 2018

Quantitative Ratiometric Ca2+ Imaging to Assess Cell Viability.

scientific article

Rapid Ca2+ flux through the transverse tubular membrane, activated by individual action potentials in mammalian skeletal muscle.

scientific article

Regulation of murine cardiac contractility by activation of α(1A)-adrenergic receptor-operated Ca(2+) entry.

scientific article published on 5 May 2011

Resting membrane potentials recorded on-site in intact skeletal muscles from deep sea fish (Sigmops gracile) salvaged from depths up to 1.000 m

scientific article published on 21 February 2008

Reversibility of high pressure effects on the contractility of skeletal muscle

scientific article published on 01 January 2001

S100A1 DNA-based Inotropic Therapy Protects Against Proarrhythmogenic Ryanodine Receptor 2 Dysfunction.

scientific article published on 25 May 2015

S100A1 decreases calcium spark frequency and alters their spatial characteristics in permeabilized adult ventricular cardiomyocytes

scientific article

Second Harmonic Generation Microscopy Probes Different States of Motor Protein Interaction in Myofibrils ⬇️

scientific article published on September 22, 2010

Second harmonic imaging of intrinsic signals in muscle fibers in situ.

scientific article

Septic cardiomyopathy in rat LPS-induced endotoxemia: relative contribution of cellular diastolic Ca(2+) removal pathways, myofibrillar biomechanics properties and action of the cardiotonic drug levosimendan.

scientific article

Single muscle fibre biomechanics and biomechatronics - The challenges, the pitfalls and the future

scientific article published on 27 June 2019

Step-by-step guide to building an inexpensive 3D printed motorized positioning stage for automated high-content screening microscopy.

scientific article

Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

scientific article

Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P. falciparum, and Cervical and Breast Cancer

scientific article published on 19 October 2018

Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells.

scientific article published in June 2017

Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents

scientific article published on 21 December 2017

Synthesis of artemisinin-derived di/tri-mers and dendrimers, investigation of their activity against P. falciparum and cytomegalovirus, and insights into their mechanisms of action.

scientific article published on 23 March 2018

Synthesis of new betulinic acid/betulin-derived dimers and hybrids with potent antimalarial and antiviral activities

scientific article published on 14 November 2018

Taking a deep look: modern microscopy technologies to optimize the design and functionality of biocompatible scaffolds for tissue engineering in regenerative medicine

scientific article

The IsoStretcher: An isotropic cell stretch device to study mechanical biosensor pathways in living cells

scientific article published on 09 March 2016

The MyoRobot: A novel automated biomechatronics system to assess voltage/Ca2+ biosensors and active/passive biomechanics in muscle and biomaterials.

scientific article published on 7 December 2017

The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill.

scientific article

The Toxic Effects of S(+)-Ketamine on Differentiating Neurons In Vitro as a Consequence of Suppressed Neuronal Ca2+ Oscillations ⬇️

scientific article published on July 25, 2011

The heart in Duchenne muscular dystrophy: early detection of contractile performance alteration ⬇️

scientific article published on December 1, 2012

The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.

scientific article

The toxic effect of R350P mutant desmin in striated muscle of man and mouse

scientific article

Tissue Viability of Free Flaps after Extracorporeal Perfusion Using a Modified Hydroxyethyl Starch Solution

scientific article published on 03 December 2020

Towards in vitro DT/DNT testing: Assaying chemical susceptibility in early differentiating NT2 cells

scientific article published on 20 October 2015

Toxic effects of midazolam on differentiating neurons in vitro as a consequence of suppressed neuronal Ca2+-oscillations.

scientific article published on 6 September 2011

Ultra-rapid activation and deactivation of store-operated Ca2+ entry in skeletal muscle

scientific article published on 01 May 2010

Understanding critical illness myopathy: approaching the pathomechanism

scientific article published on 01 July 2005

Unloaded speed of shortening in voltage-clamped intact skeletal muscle fibers from wt, mdx, and transgenic minidystrophin mice using a novel high-speed acquisition system.

scientific article published on 18 April 2008

Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle

scientific article published on 28 April 2010

Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission

scientific article

Weak by the machines: muscle motor protein dysfunction - a side effect of intensive care unit treatment

scientific article published on 7 April 2017

[Critical illness myopathy in intensive care patients. Pathogenetic concepts and clinical management]

scientific article published on 01 December 2006

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