Search filters

List of works by Isao Hozumi

A Golgi-targeting fluorescent probe for labile Fe(ii) to reveal an abnormal cellular iron distribution induced by dysfunction of VPS35

scientific article published on 26 November 2018

A novel calpain inhibitor, ((1S)-1((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl) carbamic acid 5-methoxy-3-oxapentyl ester, protects neuronal cells from cerebral ischemia-induced damage in mice

scientific article

A novel monoclonal antibody which reacts with a high molecular weight neuronal cytoplasmic protein and myelin basic protein (MBP) in a patient with macroglobulinemia.

scientific article published in May 1997

Accumulation of glycosphingolipids in spinal and sympathetic ganglia of a symptomatic heterozygote of Fabry's disease

scientific article published on 01 May 1989

Administration of prosaposin ameliorates spatial learning disturbance and reduces cavity formation following stab wounds in rat brain.

scientific article

Anti-endothelial cell antibodies in patients with cerebral small vessel disease.

scientific article published in November 2012

Association between metallothionein genes polymorphisms and sporadic amyotrophic lateral sclerosis in a Japanese population.

scientific article published in March 2006

Attenuation of cadmium-induced testicular injury in metallothionein-III null mice.

scientific article published on 17 September 2010

Autoantibodies against glutamate receptor epsilon2-subunit detected in a subgroup of patients with reversible autoimmune limbic encephalitis.

scientific article

Biochemistry and neurobiology of prosaposin: a potential therapeutic neuro-effector.

scientific article published on June 2009

Brain injury and growth inhibitory factor (GIF)--a minireview.

scientific article published on March 1998

Cerebellar Ataxia and Peripheral Neuropathy due to Chronic Bromvalerylurea Poisoning ⬇️

scientific article published on October 1, 1997

Changes in anti-HuD antibody titers in the long-term course in paraneoplastic sensory neuropathy

scientific article published on 01 January 1997

Changes of growth inhibitory factor after stab wounds in rat brain.

scientific article

Characterization of canine dental pulp cells and their neuroregenerative potential.

scientific article published on 14 July 2015

Cilostazol reduces ischemic brain damage partly by inducing metallothionein-1 and -2.

scientific article published on 6 September 2006

Conditioned medium of dental pulp cells stimulated by Chinese propolis show neuroprotection and neurite extension in vitro.

scientific article

DNA microarray analysis of transcriptional responses of mouse spinal cords to physical exercise

article

Diffuse skeletal muscles uptake of [18F] fluorodeoxyglucose on positron emission tomography in primary muscle peripheral T-cell lymphoma.

scientific article published on 15 September 2011

Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies.

scientific article published on 12 January 2017

Effects of gem-dihydroperoxides against mutant copper‑zinc superoxide dismutase-mediated neurotoxicity

scientific article published on 05 September 2018

Elevated Anti–Heat Shock Protein 60 Antibody Titer is Related to White Matter Hyperintensities

scientific article published on 14 October 2010

Evaluation of SLC20A2 mutations that cause idiopathic basal ganglia calcification in Japan

scientific article published on 24 January 2014

Exercise induces metallothioneins in mouse spinal cord

scientific article published on 30 May 2009

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

scientific article

Expression of growth inhibitory factor (GIF) in normal and injured rat brains

scientific article published on 01 July 1995

Fasudil and ozagrel in combination show neuroprotective effects on cerebral infarction after murine middle cerebral artery occlusion

scientific article published on 14 April 2011

Functional evaluation of PDGFB-variants in idiopathic basal ganglia calcification, using patient-derived iPS cells

scientific article published on 05 April 2019

Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain

scientific article published on 28 November 2005

High Levels of Copper, Zinc, Iron and Magnesium, but not Calcium, in the Cerebrospinal Fluid of Patients with Fahr’s Disease

scientific article

High prevalence of autoantibodies against phosphoglycerate mutase 1 in patients with autoimmune central nervous system diseases.

scientific article published on 6 December 2009

ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis.

scientific article published on 23 February 2013

Identification of antibodies as biological markers in serum from multiple sclerosis patients by immunoproteomic approach

scientific article published on 04 December 2010

Immunoreactivity of growth inhibitory factor in normal rat brain and after stab wounds--an immunocytochemical study using confocal laser scan microscope

scientific journal article

Induced pluripotent stem cells derived from a patient with familial idiopathic basal ganglia calcification (IBGC) caused by a mutation in SLC20A2 gene.

scientific article

Inorganic phosphorus (Pi) in CSF is a biomarker for SLC20A2-associated idiopathic basal ganglia calcification (IBGC1)

scientific article published on 08 March 2018

Involvement of CHOP, an ER-stress apoptotic mediator, in both human sporadic ALS and ALS model mice

scientific article published on 04 September 2009

Is there a delayed gastric emptying of patients with early-stage, untreated Parkinson’s disease? An analysis using the 13C-acetate breath test

article

Is there a difference in gastric emptying between myotonic dystrophy type 1 patients with and without gastrointestinal symptoms?

scientific article published on 24 January 2013

Is there delayed gastric emptying in patients with multiple system atrophy? An analysis using the (13)C-acetate breath test.

scientific article published on 5 January 2012

Late-onset Patients with Sporadic Amyotrophic Lateral Sclerosis in Japan have a Higher Progression Rate of ALSFRS-R at the Time of Diagnosis ⬇️

scientific article published on March 15, 2012

Linkage mapping of the gene for Charcot-Marie-Tooth disease type 2 to chromosome 1p (CMT2A) and the clinical features of CMT2A

scientific article

Living with idiopathic basal ganglia calcification 3: a qualitative study describing the lives and illness of people diagnosed with a rare neurological disease

scientific article

Localization of type-III sodium-dependent phosphate transporter 2 in the mouse brain.

scientific article published on 30 July 2013

Longitudinal analysis of cytokines and chemokines in the cerebrospinal fluid of a patient with Neuro-Sweet disease presenting with recurrent encephalomeningitis

scientific article published on 01 February 2008

Marked asymmetry of putaminal pathology in an MSA-P patient with Pisa syndrome.

scientific article

Markedly Ring-enhanced Optic Nerves Due to Metastasis of Signet-ring Cell Gastric Carcinoma

article

Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors

scientific article published on 30 September 2009

Metallothionein-3 is expressed in the brain and various peripheral organs of the rat

scientific article published on 18 April 2008

Metallothionein-III knockout mice aggravates the neuronal damage after transient focal cerebral ischemia

scientific journal article

Metallothionein-III prevents neuronal death and prolongs life span in amyotrophic lateral sclerosis model mice

article

Methylmercury causes epigenetic suppression of the tyrosine hydroxylase gene in an in vitro neuronal differentiation model

scientific article published on 02 June 2018

MicroRNA-5572 Is a Novel MicroRNA-Regulating SLC30A3 in Sporadic Amyotrophic Lateral Sclerosis

scientific article published on 24 June 2020

Microarray analysis of the liver in metallothionein-III null mice treated with cadmium.

scientific article published in April 2010

Motor-dominant chronic inflammatory demyelinating polyneuropathy.

scientific article published on 22 November 2009

Neuromyelitis optica in Japanese sisters.

scientific article published on 15 November 2011

Neuroprotective effect of 5-aminolevulinic acid against low inorganic phosphate in neuroblastoma SH-SY5Y cells.

scientific article published on 18 July 2017

Neuroprotective effect of erythropoietin, and role of metallothionein-1 and -2, in permanent focal cerebral ischemia.

scientific article

Occurrence of myelin-associated glycoprotein (MAG)-like immunoreactivity in some nervous, endocrine, and immune-related cells of the rat. An immunohistochemical study.

scientific article published in May 1997

Patterns of growth inhibitory factor (GIF) and glial fibrillary acidic protein relative level changes differ following left middle cerebral artery occlusion in rats.

scientific article published in February 1996

Patterns of levels of biological metals in CSF differ among neurodegenerative diseases.

scientific article published on 2 February 2011

Protective function of SLC30A10 induced via PERK-ATF4 pathway against 1-methyl-4-phenylpyridinium.

scientific article

Protective roles of SLC30A3 against endoplasmic reticulum stress via ERK1/2 activation.

scientific article published on 24 September 2016

Proteomic analysis of autoantibodies in neuropsychiatric systemic lupus erythematosus patient with white matter hyperintensities on brain MRI

scientific article published on 01 January 2008

Quantitative aspects of reactive gliosis: a review

scientific article

Regulation of gene expression in response to brain injury: enhanced expression and alternative splicing of rat prosaposin (SGP-1) mRNA in injured brain

scientific article

Review of relevance between metal homeostasis and neurodegenerative disease.

scientific article

Roles and therapeutic potential of metallothioneins in neurodegenerative diseases.

scientific article published on January 2013

SA4503, a sigma-1 receptor agonist, suppresses motor neuron damage in in vitro and in vivo amyotrophic lateral sclerosis models

scientific article published on 12 December 2013

SLC20A2 variants cause dysfunctional phosphate transport activity in endothelial cells induced from Idiopathic Basal Ganglia Calcification patients-derived iPSCs

scientific article published on 28 January 2019

Selective cauda equina hypertrophy with idiopathic inflammation.

scientific article published in August 2008

Serial monitoring of basal metabolic rate for therapeutic evaluation in an Isaacs' syndrome patient with chronic fluctuating symptoms.

scientific article published in March 2010

Shared carbohydrate antigenic determinant between the myelin-associated glycoprotein (MAG) and lung cancers. An immunohistochemical study by an anti-MAG IgM monoclonal antibody

scientific article published on 01 June 1987

Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology.

scientific article

Subcellular localization of growth inhibitory factor in rat brain: light and electron microscopic immunohistochemical studies

scientific journal article

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

scientific article published in February 1998

The Novel gem-Dihydroperoxide 12AC3O Suppresses High Phosphate-Induced Calcification via Antioxidant Effects in p53LMAco1 Smooth Muscle Cells ⬇️

scientific article published on 29 June 2020

The effects of Brazilian green propolis that contains flavonols against mutant copper-zinc superoxide dismutase-mediated toxicity

scientific article published on 6 June 2017

The expression of metallothioneins is diminished in the spinal cords of patients with sporadic ALS

scientific article published on 01 October 2008

The potential of GPNMB as novel neuroprotective factor in amyotrophic lateral sclerosis ⬇️

scientific article published on August 13, 2012

The type III transporters (PiT-1 and PiT-2) are the major sodium-dependent phosphate transporters in the mice and human brains.

scientific article published on 25 February 2016

Venous congestive myelopathy of the cervical spinal cord: an autopsy case showing a rapidly progressive clinical course.

scientific article

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis

scientific article published on 03 October 2014

[Case report; Two cases of neurolymphomatosis as a manifestation of relapsed non-Hodgkin lymphoma]

scientific article published on 01 January 2012

[Progress on the Pathophysiology of Idiopathic Basal Ganglia Calcification]

scientific article published on 01 January 2019

p-Coumaric Acid Has Protective Effects against Mutant Copper-Zinc Superoxide Dismutase 1 via the Activation of Autophagy in N2a Cells

scientific article published on 16 June 2019

Paulina is supported by:

About Paulina

Help