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List of works by Margreet Vissers

A functional NADPH oxidase prevents caspase involvement in the clearance of phagocytic neutrophils

scientific article published on 16 April 2007

A genetically engineered mutant of alpha 1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease

scientific article published on 01 December 1984

A randomised cross-over pharmacokinetic bioavailability study of synthetic versus kiwifruit-derived vitamin C

scientific article published on 11 November 2013

A randomized steady-state bioavailability study of synthetic versus natural (kiwifruit-derived) vitamin C

scientific article published on 17 September 2013

A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils.

scientific article

Activation of human neutrophil gelatinase by endogenous serine proteinases

scientific article published on January 1988

Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels

scientific article published on 3 April 2019

Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation

scientific article published on 18 October 2017

Ascorbate as a co-factor for fe- and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression

scientific article

Ascorbate availability affects tumor implantation-take rate and increases tumor rejection in Gulo-/- mice

scientific article published on 8 April 2016

Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1alpha

scientific article published on 30 January 2007

Ascorbate deficiency results in impaired neutrophil apoptosis and clearance and is associated with up-regulation of hypoxia-inducible factor 1α.

scientific article published in May 2007

Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells

scientific article

Ascorbate modulates the hypoxic pathway by increasing intracellular activity of the HIF hydroxylases in renal cell carcinoma cells

scientific article published on 15 May 2019

Bacterial killing by neutrophils in hypertonic environments.

scientific article

Beating the blues--the association between fruit and vegetable intake and improved mood

scientific article published on 18 October 2013

Bioavailability of vitamin C from kiwifruit in non-smoking males: determination of 'healthy' and 'optimal' intakes

scientific article

Bioavailable Blueberry-Derived Phenolic Acids at Physiological Concentrations Enhance Nrf2-Regulated Antioxidant Responses in Human Vascular Endothelial Cells

scientific article published on 26 December 2017

Changes in ascorbate levels on stimulation of human neutrophils

scientific article published on 01 September 1983

Chloramines and hypochlorous acid oxidize erythrocyte peroxiredoxin 2

scientific article published on 27 August 2009

Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils

scientific article published on August 1988

Cleavage of alpha 1-antitrypsin by human neutrophil collagenase

scientific article published on 01 January 1992

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1

scientific article published on 02 October 2019

Consumption of vitamin C is below recommended daily intake in many cancer patients and healthy volunteers in Christchurch

scientific article published on 7 March 2014

Correction: Conner et al. KiwiC for Vitality: Results of a Placebo-Controlled Trial Testing the Effects of Kiwifruit or Vitamin C Tablets on Vitality in Adults with Low Vitamin C Levels. 2020, , 2898

Degradation of glomerular basement membrane by human neutrophils in vitro ⬇️

scientific article published on June 19, 1984

Detection of apoptosis by caspase-3 activation in tracheal aspirate neutrophils from premature infants: relationship with NF-kappaB activation

scientific article published on 16 December 2004

Dietary ascorbate intake affects steady state tissue concentrations in vitamin C-deficient mice: tissue deficiency after suboptimal intake and superior bioavailability from a food source (kiwifruit)

scientific article published in December 2010

Different effects of hypochlorous acid on human neutrophil metalloproteinases: Activation of collagenase and inactivation of collagenase and gelatinase ⬇️

scientific article published on 01 February 1992

Elevated seminal plasma myeloperoxidase is associated with a decreased sperm concentration in young men.

scientific article

Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate

scientific article published on 22 October 2020

Enhanced human neutrophil vitamin C status, chemotaxis and oxidant generation following dietary supplementation with vitamin C-rich SunGold kiwifruit

scientific article published on 9 April 2015

Erythrocyte Ascorbate Is a Potential Indicator of Steady-State Plasma Ascorbate Concentrations in Healthy Non-Fasting Individuals

scientific article published on 6 February 2020

Extracellular oxidation by taurine chloramine activates ERK via the epidermal growth factor receptor

scientific article published on 27 May 2004

Fatty acid chlorohydrins and bromohydrins are cytotoxic to human endothelial cells

scientific article published on 01 January 2001

Gelatinase contributes to the degradation of glomerular basement membrane collagen by human neutrophils.

scientific article published in March 1988

Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione disulfide

scientific article published on 29 March 2001

Good nutrition matters: hypovitaminosis C associated with depressed mood and poor wound healing

scientific article published on September 21, 2012

Gulonolactone Addition to Human Hepatocellular Carcinoma Cells with Gene Transfer of Gulonolactone Oxidase Restores Ascorbate Biosynthesis and Reduces Hypoxia Inducible Factor 1

scientific article published on 5 March 2014

Hemoglobin Volga, beta 27 (B9) Ala replaced by Asp: functional and clinical correlations of an unstable hemoglobin

scientific article published on 01 January 1980

High Vitamin C Status Is Associated with Elevated Mood in Male Tertiary Students

scientific article published on 16 July 2018

Human neutrophil collagenase cleaves alpha 1-antitrypsin

scientific article published on September 1990

Human skeletal muscle ascorbate is highly responsive to changes in vitamin C intake and plasma concentrations ⬇️

scientific article published on February 27, 2013

Hypochlorous Acid Disrupts the Adhesive Properties of Subendothelial Matrix ⬇️

scientific article published on January 1, 1997

Hypochlorous acid causes caspase activation and apoptosis or growth arrest in human endothelial cells

scientific article published in December 1999

Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival

scientific article

Hypothiocyanous acid is a potent inhibitor of apoptosis and caspase 3 activation in endothelial cells

scientific article published on 13 July 2010

Increased Tumor Ascorbate is Associated with Extended Disease-Free Survival and Decreased Hypoxia-Inducible Factor-1 Activation in Human Colorectal Cancer

scientific article published on 4 February 2014

Inhibition by nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine

scientific article published on August 1987

Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine

scientific article published on 01 September 1987

Inhibition of neutrophil-mediated degradation of isolated basement membrane collagen by nonsteroidal antiinflammatory drugs that inhibit degranulation

scientific article published on 01 August 1987

Intracellular ascorbate enhances hypoxia-inducible factor (HIF)-hydroxylase activity and preferentially suppresses the HIF-1 transcriptional response

scholarly article

KiwiC for Vitality: Results of a Randomized Placebo-Controlled Trial Testing the Effects of Kiwifruit or Vitamin C Tablets on Vitality in Adults with Low Vitamin C Levels

scientific article published on 22 September 2020

Let them eat fruit! The effect of fruit and vegetable consumption on psychological well-being in young adults: A randomized controlled trial

scientific article published on 3 February 2017

Living with a killer: the effects of hypochlorous acid on mammalian cells

scientific article

Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid

scientific article published on 01 October 1999

Low Vitamin C Status in Patients with Cancer Is Associated with Patient and Tumor Characteristics

scientific article published on 5 August 2020

Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer

scientific article published on 22 June 2010

Marginal Ascorbate Status (Hypovitaminosis C) Results in an Attenuated Response to Vitamin C Supplementation

scientific article published on 3 June 2016

Maternal Vitamin C Intake during Pregnancy Influences Long-Term Offspring Growth with Timing- and Sex-Specific Effects in Guinea Pigs

scholarly article

Membrane changes associated with lysis of red blood cells by hypochlorous acid

scientific article

Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins ⬇️

scientific article published on October 1, 1997

Modulation of hypoxia-inducible factor-1 alpha in cultured primary cells by intracellular ascorbate

scientific article published on 30 November 2006

Mood improvement in young adult males following supplementation with gold kiwifruit, a high-vitamin C food

scientific article

Multiple nutrient insufficiencies--hypovitaminosis D and C in young adult New Zealand males

scientific article published on October 26, 2012

Myeloperoxidase

scientific article published on 01 January 2000

Myeloperoxidase-dependent lipid peroxidation promotes the oxidative modification of cytosolic proteins in phagocytic neutrophils

scientific article

Myeloperoxidase-dependent oxidative inactivation of neutrophil neutral proteinases and microbicidal enzymes

scientific article published on July 1987

Neutrophils adherent to a nonphagocytosable surface (glomerular basement membrane) produce oxidants only at the site of attachment

scientific article published on 01 July 1985

Nuclear factor kappaB activation in pulmonary leukocytes from infants with hyaline membrane disease: associations with chorioamnionitis and Ureaplasma urealyticum colonization

scientific article published on 03 March 2005

Oxidant-mediated phosphatidylserine exposure and macrophage uptake of activated neutrophils: possible impairment in chronic granulomatous disease.

scientific article

Oxidation of 2-cys peroxiredoxins in human endothelial cells by hydrogen peroxide, hypochlorous acid, and chloramines

scientific article published on 2 March 2012

Oxidation of intracellular glutathione after exposure of human red blood cells to hypochlorous acid

scientific article published on April 1995

Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl

scientific article

Oxidative damage to fibronectin. II. The effect of H2O2 and the hydroxyl radical

scientific article published on 01 March 1991

Oxidative inactivation of neutrophil granule proteinases: implications for neutrophil-mediated proteolysis

scientific article

Parenteral vitamin C for palliative care of terminal cancer patients

scientific article

Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice

scientific article published on 24 August 2016

Pharmacokinetic modeling of ascorbate diffusion through normal and tumor tissue

scientific article published on 30 September 2014

Physiological Concentrations of Blueberry-Derived Phenolic Acids Reduce Monocyte Adhesion to Human Endothelial Cells

scientific article published on 28 June 2019

Potential Mechanisms of Action for Vitamin C in Cancer: Reviewing the Evidence

scientific article published on 3 July 2018

Prolonged exposure to hypoxia induces an autophagy-like cell survival program in human neutrophils

scientific article published on 14 August 2019

Proteinase-antiproteinase balance in tracheal aspirates from neonates

scientific article published on 01 February 1994

Rapid proteolysis of unstable globins in human bone marrow ⬇️

scientific article published on 01 March 1983

Regulation of apoptosis by vitamin C. Specific protection of the apoptotic machinery against exposure to chlorinated oxidants.

scientific article

Regulation of the 2-oxoglutarate-dependent dioxygenases and implications for cancer

scientific article

Relief from cancer chemotherapy side effects with pharmacologic vitamin C

scientific article published on 24 January 2014

Reply to Vorland et al. Mixed Random and Nonrandom Allocation, and Group Randomization Have Been Mislabeled and Misanalysed, Necessitating Reanalysis. Comment on “Conner et al. KiwiC for Vitality: Results of a Randomized Placebo-Controlled Trial Te

scientific article published on 30 September 2022

Restoring physiological levels of ascorbate slows tumor growth and moderates HIF-1 pathway activity in Gulo(-/-) mice

scientific article

Roles of superoxide and myeloperoxidase in ascorbate oxidation in stimulated neutrophils and H2O2-treated HL60 cells

scientific article published on 5 July 2011

Synthetic or food-derived vitamin C - are they equally bioavailable?

scientific article published on 28 October 2013

The Association Between Ascorbate and the Hypoxia-Inducible Factors in Human Renal Cell Carcinoma Requires a Functional Von Hippel-Lindau Protein

scientific article published on 30 November 2018

The Bioavailability of Vitamin C from Kiwifruit

scientific article published on January 1, 2013

The Roles of Vitamin C in Skin Health

scientific article published on 12 August 2017

The Vitamin C Status of Patients with Diabetic Foot Ulcers

scientific article published on 26 October 2020

The development and effectiveness of an ecological momentary intervention to increase daily fruit and vegetable consumption in low-consuming young adults

scientific article

The effect of hypochlorous acid on the expression of adhesion molecules and activation of NF-kappaB in cultured human endothelial cells

scientific article published in February 2002

The effect of intracellular ascorbate on the susceptibility of HL60 and Jurkat cells to chemotherapy agents

scientific article

The effect of intravenous vitamin C on cancer- and chemotherapy-related fatigue and quality of life

scientific article

The effect of oxidants on neutrophil-mediated degradation of glomerular basement membrane collagen

scientific article published on 01 December 1986

The role of oxidants and vitamin C on neutrophil apoptosis and clearance

scientific article published on June 2004

Unstable Haemoglobin Haemolytic Crises: Contributions of Pyrexia and Neutrophil Oxidants ⬇️

scientific article published on 01 September 1981

Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study

scientific article published on 3 August 2017

Vitamin C and immune cell function in inflammation and cancer

scholarly article

Vitamin C supplementation and kidney stone risk

scientific article published on 18 October 2013

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