List of works by Elisa Ciraolo

Crossroads of PI3K and Rac pathways.

scientific article published on April 2015

Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits

scientific article published on 7 October 2016

Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility.

scientific article

Genetic Deletion and Pharmacological Inhibition of PI3K γ Reduces Neutrophilic Airway Inflammation and Lung Damage in Mice with Cystic Fibrosis-Like Lung Disease

scientific article published on 21 June 2015

Genetic evidence for a predominant role of PI3Kbeta catalytic activity in ITAM- and integrin-mediated signaling in platelets.

scientific article

Groebke multicomponent reaction and subsequent nucleophilic aromatic substitution for a convenient synthesis of 3,8-diaminoimidazo[1,2-a]pyrazines as potential kinase inhibitors.

scientific article

Hyperactivity of Rac1-GTPase pathway impairs neuritogenesis of cortical neurons by altering actin dynamics.

scientific article

Identification of a Potent Phosphoinositide 3-Kinase Pan Inhibitor Displaying a Strategic Carboxylic Acid Group and Development of Its Prodrugs.

scientific article published on 31 August 2017

Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis

scientific article published in Nature Communications

Methods to measure the enzymatic activity of PI3Ks

scientific article published on January 2014

Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function

scientific article published in October 2017

Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits.

scientific article published on 7 December 2017

New pre-clinical evidence of anti-inflammatory effect and safety of a substituted fluorophenyl imidazole

scientific article published on 19 January 2019

PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function

scientific article

PI3K in cancer-stroma interactions: bad in seed and ugly in soil.

scientific article published on 29 July 2013

PI3K signaling: a crossroads of metabolic regulation

scientific article published on 01 July 2009

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling

scientific article published on 23 June 2015

PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism

scientific article published on 27 October 2011

Phosphoinositide 3-kinases as a common platform for multi-hormone signaling.

scientific article published on August 2007

Rac signal adaptation controls neutrophil mobilization from the bone marrow.

scientific article

Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling.

scientific article

Sustained release of PI3K inhibitor from PHA nanoparticles and in vitro growth inhibition of cancer cell lines.

scientific article published on February 2011

Taming the PI3K team to hold inflammation and cancer at bay.

scientific article published on 05 March 2008

Targeting PI3K in Cancer: Any Good News?

scientific article published on 08 May 2013

The Guareschi Pyridine Scaffold as a Valuable Platform for the Identification of Selective PI3K Inhibitors

scientific article published on 18 September 2015

The absence of functional PI3Kgamma prevents leukocyte recruitment and ameliorates DSS-induced colitis in mice.

scientific article published on 27 March 2010

Twice upon a time: PI3K's secret double life exposed

scientific article

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