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List of works by Amrie C Grammer

A comprehensive approach to identify approved drugs and treatments for repositioning as therapies for systemic lupus erythematosus.

scientific article published on 18 September 2014

Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

scientific article published on November 2003

Analysis of CD40-CD40 ligand interactions in the regulation of human B cell function.

scientific article published on April 1997

Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.

scientific article

Are autoantibodies the targets of B-cell-directed therapy?

scientific article published on 2 August 2011

Bidirectional regulation of human B cell responses by CD40-CD40 ligand interactions.

scientific article published in May 1997

CD154-CD40 interactions mediate differentiation to plasma cells in healthy individuals and persons with systemic lupus erythematosus.

scientific article

CD40-mediated regulation of immune responses by TRAF-dependent and TRAF-independent signaling mechanisms.

scientific article

Comparative characteristics of mu chain and alpha chain transcripts expressed by individual tonsil plasma cells.

scientific article

Different patterns of bcl-6 and p53 gene mutations in tonsillar B cells indicate separate mutational mechanisms.

scientific article published in November 2002

Drug Repositioning Strategies for the Identification of Novel Therapies for Rheumatic Autoimmune Inflammatory Diseases

scientific article published on August 2017

Drug repositioning in SLE: crowd-sourcing, literature-mining and Big Data analysis.

scientific article

Expression of recombination activating genes 1 and 2 in peripheral B cells of patients with systemic lupus erythematosus

scientific article published on 01 May 2002

Expression, regulation, and function of B cell-expressed CD154 in germinal centers.

scientific article published in October 1999

Flow cytometric measurement of fluorescence (Förster) resonance energy transfer from cyan fluorescent protein to yellow fluorescent protein using single-laser excitation at 458 nm.

scientific article

Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser.

scientific article

Genomic Identification of Low-Density Granulocytes and Analysis of Their Role in the Pathogenesis of Systemic Lupus Erythematosus

scientific article published on 24 April 2019

IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells

scientific article published on 01 March 2007

Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus

scientific article published in PLoS ONE

Ligation of CD40 influences the function of human Ig-secreting B cell hybridomas both positively and negatively

scientific article published on 01 May 1996

Machine learning approaches to predict lupus disease activity from gene expression data

scientific article published on 03 July 2019

Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus.

scientific article

RAG1 and RAG2 expression by B cell subsets from human tonsil and peripheral blood.

scientific article published in January 2001

Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

scientific article

Regulation of the germinal center gene program by interferon (IFN) regulatory factor 8/IFN consensus sequence-binding protein

Repertoire analysis of anergic B cells from patients with systemic lupus erythematosus.

scientific article published on 12 September 2003

Sustained secretion of immunoglobulin by long-lived human tonsil plasma cells.

scientific article published on 9 August 2007

T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue.

scientific article published on 13 February 2007

TNF receptor-associated factor-3 signaling mediates activation of p38 and Jun N-terminal kinase, cytokine secretion, and Ig production following ligation of CD40 on human B cells ⬇️

scientific article published on August 1, 1998

TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation.

scientific article published on 21 September 2004

The Impact of Protein Acetylation/Deacetylation on Systemic Lupus Erythematosus ⬇️

scientific article published on 12 December 2018

The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.

scientific article published on 27 March 2007

The relationship between hepatic immunoglobulin production and CD154 expression in chronic liver diseases

scientific article published on 01 March 2006

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