List of works - Dušan Hesek

A Type VI secretion system delivers a cell-wall amidase to target bacterial competitors

scientific article published on 12 April 2020

A mechanism-based inhibitor targeting the DD-transpeptidase activity of bacterial penicillin-binding proteins.

scientific article

A neutral upper to lower rim linked bis-calix[4]arene receptor that recognises anionic guest species

A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition

scientific article published on February 2009

A practical synthesis of nitrocefin

scientific article published in January 2005

Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa

scientific article

Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall

scientific article published in February 2005

Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases

scientific article

Amidase Activity of AmiC Controls Cell Separation and Stem Peptide Release and Is Enhanced by NlpD in Neisseria gonorrhoeae

scientific article published on 16 March 2016

Anion Recognition by Redox-Responsive Ditopic Bis-Cobaltocenium Receptor Molecules Including a Novel Calix[4]arene Derivative That Binds a Dicarboxylate Dianion

Anion recognition by novel ruthenium(II) bipyridyl calix[4]arene receptor molecules

scholarly article by Paul D. Beer et al published 1994 in Journal of the Chemical Society. Chemical communications

Bacterial AmpD at the crossroads of peptidoglycan recycling and manifestation of antibiotic resistance

scientific article published on July 2009

Catalytic spectrum of the penicillin-binding protein 4 of Pseudomonas aeruginosa, a nexus for the induction of β-lactam antibiotic resistance

scientific journal article

Cell-Wall Remodeling by the Zinc-Protease AmpDh3 from Pseudomonas aeruginosa

scientific article

Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3'')-Ii/AAC(6')-IId from Serratia marcescens

scientific article published in July 2006

Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase

scientific article

Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics

scientific article

Complications from dual roles of sodium hydride as a base and as a reducing agent

scientific article published on March 2009

Corrigenda

scholarly article published in Journal of the Chemical Society. Chemical communications

Corrigendum: Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance.

scientific article published in October 2016

Crystal Structures of Penicillin-Binding Protein 6 from Escherichia coli

scientific article

Deciphering the Nature of Enzymatic Modifications of Bacterial Cell Walls

scientific article published on 7 June 2017

Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1

scientific article

Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa.

scientific article published on 9 April 2018

Facile preparation of a highly functionalized tetrahydropyran by catalytic hydrogenation of an oxazoline

scientific article

From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa

scientific article published on 27 January 2017

Inhibitors for Bacterial Cell-Wall Recycling ⬇️

scientific article published on January 19, 2012

Lysine Nζ-Decarboxylation Switch and Activation of the β-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus ⬇️

scientific article published on July 20, 2011

Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall

scientific article

Lytic transglycosylases LtgA and LtgD perform distinct roles in remodeling, recycling and releasing peptidoglycan in Neisseria gonorrhoeae

scientific article published on 8 September 2016

Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram‐negative bacterial outer membrane ⬇️

scientific article published on September 30, 2011

Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus

scientific article published on 3 February 2006

Mechanistic characterization of the bifunctional aminoglycoside-modifying enzyme AAC(3)-Ib/AAC(6')-Ib' from Pseudomonas aeruginosa

scientific article published on 07 April 2007

Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance

scientific article published on 25 April 2016

Potentiation of the activity of β-lactam antibiotics by farnesol and its derivatives

scientific article published on 31 January 2018

Reaction Products and the X-ray Structure of AmpDh2, a Virulence Determinant of Pseudomonas aeruginosa

scientific article

Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall.

scientific article

Reactions of the three AmpD enzymes of Pseudomonas aeruginosa

scientific journal article

Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae

scientific article

Regiospecific syntheses of 6alpha-(1R-Hydroxyoctyl)penicillanic acid and 6beta-(1R-hydroxyoctyl)penicillanic acid as mechanistic probes of class D beta-lactamases

scientific article published on June 2009

Shared functional attributes between the mecA gene product of Staphylococcus sciuri and penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.

scientific article published on 13 June 2007

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in -Lactam Resistance

scientific article

Structural Basis of the Heterodimer Formation between Cell Shape-Determining Proteins Csd1 and Csd2 from Helicobacter pylori

scientific article

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

scientific article

Structural and photophysical characterisation of coordination and optical isomers of mononuclear ruthenium(ii) polypyridyl 1,2,4-triazole complexesElectronic supplementary information (ESI) available: analytical and semipreparative HPLC chromatograms

Structural basis for the recognition of muramyltripeptide by Helicobacter pylori Csd4, a D,L-carboxypeptidase controlling the helical cell shape

scientific article

Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins

scientific article

Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli

scientific article

Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase

scientific article

Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors

scientific article

Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence

scientific article

Sulfonylation-induced N- to O-acetyl migration in 2-acetamidoethanol derivatives

scientific article

Synthesis and Characterization of Novel Acyclic, Macrocyclic, and Calix[4]arene Ruthenium(II) Bipyridyl Receptor Molecules That Recognize and Sense Anions

article

Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol

scientific article

Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.

scientific article published on 15 November 2017

Synthesis of a fragment of bacterial cell wall

scientific article published in March 2004

Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors

scientific article

Synthetic peptidoglycan motifs for germination of bacterial spores

scientific article

Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria

scientific article published in February 2004

The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of L,D-Carboxypeptidase.

scientific article

The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity

scientific article published on 6 April 2016

Thermodynamics of interactions of vancomycin and synthetic surrogates of bacterial cell wall

scientific article published on June 2006

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials

scientific article published on 12 December 2015

Three-dimensional structure of the bacterial cell wall peptidoglycan

scholarly article

Total synthesis of N-acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and evaluation of its turnover by AmpD from Escherichia coli

scientific article published on April 2009

Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa

scientific article

Use of silver carbonate in the Wittig reaction

scientific article published on 26 November 2013

Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury

scientific article published on 4 August 2015

List of works by Dušan Hesek

A Type VI secretion system delivers a cell-wall amidase to target bacterial competitors

A mechanism-based inhibitor targeting the DD-transpeptidase activity of bacterial penicillin-binding proteins.

A neutral upper to lower rim linked bis-calix[4]arene receptor that recognises anionic guest species

A potent gelatinase inhibitor with anti-tumor-invasive activity and its metabolic disposition

A practical synthesis of nitrocefin

Activation by Allostery in Cell-Wall Remodeling by a Modular Membrane-Bound Lytic Transglycosylase from Pseudomonas aeruginosa

Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall

Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases

Amidase Activity of AmiC Controls Cell Separation and Stem Peptide Release and Is Enhanced by NlpD in Neisseria gonorrhoeae

Anion Recognition by Redox-Responsive Ditopic Bis-Cobaltocenium Receptor Molecules Including a Novel Calix[4]arene Derivative That Binds a Dicarboxylate Dianion

Anion recognition by novel ruthenium(II) bipyridyl calix[4]arene receptor molecules

Bacterial AmpD at the crossroads of peptidoglycan recycling and manifestation of antibiotic resistance

Catalytic spectrum of the penicillin-binding protein 4 of Pseudomonas aeruginosa, a nexus for the induction of β-lactam antibiotic resistance

Cell-Wall Remodeling by the Zinc-Protease AmpDh3 from Pseudomonas aeruginosa

Characterization of the bifunctional aminoglycoside-modifying enzyme ANT(3'')-Ii/AAC(6')-IId from Serratia marcescens

Cleavage at the stem region releases an active ectodomain of the membrane type 1 matrix metalloproteinase

Co-opting the cell wall in fighting methicillin-resistant Staphylococcus aureus: potent inhibition of PBP 2a by two anti-MRSA beta-lactam antibiotics

Complications from dual roles of sodium hydride as a base and as a reducing agent

Corrigenda

Corrigendum: Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance.

Crystal Structures of Penicillin-Binding Protein 6 from Escherichia coli

Deciphering the Nature of Enzymatic Modifications of Bacterial Cell Walls

Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1

Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa.

Facile preparation of a highly functionalized tetrahydropyran by catalytic hydrogenation of an oxazoline

From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa

Inhibitors for Bacterial Cell-Wall Recycling ⬇️

Lysine Nζ-Decarboxylation Switch and Activation of the β-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus ⬇️

Lytic transglycosylase MltB of Escherichia coli and its role in recycling of peptidoglycan strands of bacterial cell wall

Lytic transglycosylases LtgA and LtgD perform distinct roles in remodeling, recycling and releasing peptidoglycan in Neisseria gonorrhoeae

Mechanism of anchoring of OmpA protein to the cell wall peptidoglycan of the gram‐negative bacterial outer membrane ⬇️

Mechanistic basis for the action of new cephalosporin antibiotics effective against methicillin- and vancomycin-resistant Staphylococcus aureus

Mechanistic characterization of the bifunctional aminoglycoside-modifying enzyme AAC(3)-Ib/AAC(6')-Ib' from Pseudomonas aeruginosa

Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance

Potentiation of the activity of β-lactam antibiotics by farnesol and its derivatives

Reaction Products and the X-ray Structure of AmpDh2, a Virulence Determinant of Pseudomonas aeruginosa

Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall.

Reactions of the three AmpD enzymes of Pseudomonas aeruginosa

Recognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae

Regiospecific syntheses of 6alpha-(1R-Hydroxyoctyl)penicillanic acid and 6beta-(1R-hydroxyoctyl)penicillanic acid as mechanistic probes of class D beta-lactamases

Shared functional attributes between the mecA gene product of Staphylococcus sciuri and penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus.

Structural Analysis of the Role of Pseudomonas aeruginosa Penicillin-Binding Protein 5 in -Lactam Resistance

Structural Basis of the Heterodimer Formation between Cell Shape-Determining Proteins Csd1 and Csd2 from Helicobacter pylori

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

Structural and photophysical characterisation of coordination and optical isomers of mononuclear ruthenium(ii) polypyridyl 1,2,4-triazole complexesElectronic supplementary information (ESI) available: analytical and semipreparative HPLC chromatograms

Structural basis for the recognition of muramyltripeptide by Helicobacter pylori Csd4, a D,L-carboxypeptidase controlling the helical cell shape

Structural insights into the bactericidal mechanism of human peptidoglycan recognition proteins

Structure and Cell Wall Cleavage by Modular Lytic Transglycosylase MltC of Escherichia coli

Structure of Csd3 from Helicobacter pylori, a cell shape-determining metallopeptidase

Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors

Substrate recognition and catalysis by LytB, a pneumococcal peptidoglycan hydrolase involved in virulence

Sulfonylation-induced N- to O-acetyl migration in 2-acetamidoethanol derivatives

Synthesis and Characterization of Novel Acyclic, Macrocyclic, and Calix[4]arene Ruthenium(II) Bipyridyl Receptor Molecules That Recognize and Sense Anions

Synthesis and NMR characterization of (Z,Z,Z,Z,E,E,ω)-heptaprenol

Synthesis and shift-reagent-assisted full NMR assignment of bacterial (Z8,E2,ω)-undecaprenol.

Synthesis of a fragment of bacterial cell wall

Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors

Synthetic peptidoglycan motifs for germination of bacterial spores

Synthetic peptidoglycan substrates for penicillin-binding protein 5 of Gram-negative bacteria

The Cell Shape-determining Csd6 Protein from Helicobacter pylori Constitutes a New Family of L,D-Carboxypeptidase.

The Natural Product Essramycin and Three of Its Isomers Are Devoid of Antibacterial Activity

Thermodynamics of interactions of vancomycin and synthetic surrogates of bacterial cell wall

Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials

Three-dimensional structure of the bacterial cell wall peptidoglycan

Total synthesis of N-acetylglucosamine-1,6-anhydro-N-acetylmuramylpentapeptide and evaluation of its turnover by AmpD from Escherichia coli

Turnover of Bacterial Cell Wall by SltB3, a Multidomain Lytic Transglycosylase of Pseudomonas aeruginosa

Use of silver carbonate in the Wittig reaction

Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury