List of works - George C Tsokos

Autoimmunity and organ damage in systemic lupus erythematosus

scientific article published on 04 May 2020

CD25 and Protein Phosphatase 2A Cooperate to Enhance IL-2R Signaling in Human Regulatory T Cells

scientific article published on 13 May 2019

CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice.

scientific article published on 20 February 2017

Cathepsin K Deficiency Ameliorates Systemic Lupus Erythematosus-like Manifestations in Faslpr Mice.

scientific article published on 16 January 2017

Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production

scientific article published on 11 May 2016

Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype.

scientific article published on 30 March 2018

Downregulation of miR-200a-3p, Targeting CtBP2 Complex, Is Involved in the Hypoproduction of IL-2 in Systemic Lupus Erythematosus-Derived T Cells.

scientific article published on 24 April 2017

Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity

scientific article published on 01 December 2020

Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis

scientific article published on 27 September 2019

Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity

scientific article published on 12 August 2021

IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury.

scientific article

IL-23 Limits the Production of IL-2 and Promotes Autoimmunity in Lupus.

scientific article published on 23 June 2017

IL-23 reshapes kidney resident cell metabolism and promotes local kidney inflammation

scientific article published in 2021

Intracellular Activation of Complement 3 Is Responsible for Intestinal Tissue Damage during Mesenteric Ischemia.

scientific article published on 2 December 2016

Maintenance of Efficacy and Safety of Ustekinumab Through One Year in a Phase II Multicenter, Prospective, Randomized, Double-Blind, Placebo-Controlled Crossover Trial of Patients With Active Systemic Lupus Erythematosus

scientific article published on 25 November 2019

Response to ustekinumab treatment in patients with systemic lupus erythematosus is linked to suppression of serum interferon gamma levels

scientific article published on 03 October 2020

SLAMF6 as a Regulator of Exhausted CD8+ T Cells in Cancer

scientific article published on 17 July 2019

SNPs talk to genes using landlines: long-range chromatin interactions link genetic risk with epigenetic patterns in Takayasu arteritis

scientific article published on 07 August 2019

Single-cell sequencing of immune cells from anticitrullinated peptide antibody positive and negative rheumatoid arthritis

scientific article published on 17 August 2021

Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity

scientific article published on 01 December 2019

Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells

scientific article published on 05 June 2020

T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy

scientific article published on 16 January 2020

TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation

scientific article published on 13 January 2021

The gut microbiota of non-treated patients with SLE defines an autoimmunogenic and proinflammatory profile

scientific article published on 30 October 2020

The role of platelets in immune-mediated inflammatory diseases

scientific article published in 2023

cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus

scientific article published on 25 October 2019

List of works by George C Tsokos