Search filters

List of works by Frank Bretz

A graphical approach to sequentially rejective multiple test procedures

scientific article published in February 2009

A note on testing families of hypotheses using graphical procedures

scientific article published on 20 July 2014

A simple and flexible graphical approach for adaptive group-sequential clinical trials

scientific article

A unified framework for weighted parametric multiple test procedures

scientific article published on 29 March 2017

Adaptive Dunnett tests for treatment selection

Adaptive designs based on the truncated product method

scientific article

Adaptive designs for confirmatory clinical trials

scientific article published on April 2009

Adaptive designs: The Swiss Army knife among clinical trial designs?

scientific article published on 22 March 2017

Advanced multiplicity adjustment methods in clinical trials

scientific article published on 16 September 2013

Alterations of pre-mRNA splicing in human inflammatory bowel disease

article

Assessing the similarity of dose response and target doses in 2 non-overlapping subgroups.

scientific article

Author's reply: To PMID 21837623.

scientific article published on 16 January 2013

Authors' response to comments

scientific article published on February 2016

Bayesian predictive power for interim adaptation in seamless phase II/III trials where the endpoint is survival up to some specified timepoint

scientific article published in November 2007

Commentary on Parker and Weir

scientific article published on 15 July 2020

Comparing a stratified treatment strategy with the standard treatment in randomized clinical trials

scientific article published on 25 September 2016

Compatible simultaneous lower confidence bounds for the Holm procedure and other Bonferroni-based closed tests

scientific article

Confirmatory adaptive designs with Bayesian decision tools for a targeted therapy in oncology

scientific article

Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: applications and practical considerations.

scientific article

Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: general concepts

scientific article published on August 2006

Connecting Instrumental Variable methods for causal inference to the Estimand Framework

scientific article published in 2021

Correction

scientific article published on 11 February 2019

Design and analysis of dose-finding studies combining multiple comparisons and modeling procedures

scientific article published in January 2006

Designing dose finding studies with an active control for exponential families

scientific article published on 4 November 2015

Detecting dose-response using contrasts: asymptotic power and sample size determination for binomial data

scientific article

Discussion on ‘Correct and logical causal inference for binary and time‐to‐event outcomes in randomized controlled trials'

scientific article published in 2021

Dose finding - a challenge in statistics

scientific article published on August 2008

Dose response signal detection under model uncertainty

scientific article published on 30 July 2015

Estimands in clinical trials - broadening the perspective

scientific article published on 19 July 2016

Estimands: discussion points from the PSI estimands and sensitivity expert group

scientific article published on 21 March 2016

Experimental designs for small randomised clinical trials: an algorithm for choice

scientific article published on March 25, 2013

Flexible alpha allocation strategies for confirmatory adaptive enrichment clinical trials with a prespecified subgroup

scientific article published on 26 June 2018

Graphical approaches for multiple comparison procedures using weighted Bonferroni, Simes, or parametric tests

scientific article published on 12 August 2011

Hierarchical testing of multiple endpoints in group-sequential trials

scientific article published in January 2010

Identifying effective and/or safe doses by stepwise confidence intervals for ratios

scientific article published in March 2003

Innovative Approaches for Designing and Analyzing Adaptive Dose-Ranging Trials

Joint EMA, ISBS, and DR-IBS International Symposium on Biopharmaceutical Statistics: bridging drug development from research to marketing.

scientific article published in May 2013

MCP2009 - 6(th) International Conference on Multiple Comparison Procedures

scientific article published in December 2010

MCP2013 - 8th International Conference on Multiple Comparison Procedures

scientific article published in January 2015

Memory and other properties of multiple test procedures generated by entangled graphs

scientific article published on 28 December 2012

Model selection versus model averaging in dose finding studies

scientific article published on 25 May 2016

Model-based dose finding under model uncertainty using general parametric models

scientific article published on 3 December 2013

Multiple confidence intervals for selected parameters adjusted for the false coverage rate in monotone dose-response microarray experiments

scientific article published on 26 December 2016

Multiple hypotheses testing based on ordered p values--a historical survey with applications to medical research

scientific article

Multiplicity and replicability: two sides of the same coin

scientific article

Multiplicity in confirmatory clinical trials: a case study with discussion from a JSM panel

scientific article

Normal probability plots with confidence

scientific article published on 21 October 2014

On the efficiency of two-stage response-adaptive designs

scientific article published on 3 August 2012

Optimal test procedures for multiple hypotheses controlling the familywise expected loss

scientific article published in 2023

Panel forum on multiple comparison procedures: a commentary from a complex trial design and analysis plan

scientific article published on 3 April 2013

Power and sample size computations in simultaneous tests for non-inferiority based on relative margins

scientific article published in April 2006

Power and sample size when multiple endpoints are considered

scientific article published in July 2007

Practical considerations for optimal designs in clinical dose finding studies

scientific article published on March 2010

Quantitative approaches underpinning decision making

scientific article published on 28 July 2019

Rejoinder

Rejoinder to discussions on “Optimal test procedures for multiple hypotheses controlling the familywise expected loss”

scientific article published in 2023

Robustness considerations in selecting efficient two-color microarray designs

scientific article published in July 2009

Sample size and proportion of Japanese patients in multi-regional trials

scientific article published in July 2010

Seventh international French Society of Statistics meeting on statistical methods in biopharmacy: emerging topics for statistical methodology in clinical drug development

scientific article published on September 2015

Simultaneous Confidence Bands for Nonlinear Regression Models with Application to Population Pharmacokinetic Analyses

scientific article published on July 1, 2011

Simultaneous confidence bands for a percentile line in linear regression

scholarly article by Yang Han et al published January 2015 in Computational Statistics & Data Analysis

Simultaneous inference for several quantiles of a normal population with applications

scientific article published on 21 November 2012

Statistical analysis of monotone or non-monotone dose-response data from in vitro toxicological assays

scientific article

Statistical calibration and exact one-sided simultaneous tolerance intervals for polynomial regression

scholarly article by Yang Han et al published January 2016 in Journal of Statistical Planning and Inference

Symmetric graphs for equally weighted tests, with application to the Hochberg procedure

scientific article published on 27 October 2019

Test and power considerations for multiple endpoint analyses using sequentially rejective graphical procedures

scientific article published on 3 February 2011

Testing dose-response relationships with a priori unknown, possibly nonmonotone shapes

scientific article published on January 1, 2001

Trimmed weighted Simes' test for two one-sided hypotheses with arbitrarily correlated test statistics

scientific article published in December 2009

Tutorial on statistical considerations on subgroup analysis in confirmatory clinical trials

scientific article published on 28 November 2016

Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls.

scientific article published on 16 March 2015

Type I error rate control in adaptive designs for confirmatory clinical trials with treatment selection at interim

scientific article published in March 2011