Search filters

List of works by Carmella Evans-Molina

A Computational Approach for Defining a Signature of β-Cell Golgi Stress in Diabetes Mellitus

scientific article published on 20 August 2020

A case of calciphylaxis in a patient with hypoparathyroidism and normal renal function

scientific article

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: a unique presentation of a rare tumor

scientific article published in December 2016

Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

scientific article published on 09 August 2019

Achieving "PeaK-A" insulin secretion

scientific article published on May 2013

An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic beta cells

scientific article published on 7 June 2010

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

scientific article published in PLoS ONE

Associations of HbA1c with the timing of C-peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes

scientific article published on 15 April 2019

Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables

Beta cells in type 1 diabetes: mass and function; sleeping or dead?

scientific article published on 14 February 2019

Biomarkers of islet beta cell stress and death in type 1 diabetes

Biomarkers of β-Cell Stress and Death in Type 1 Diabetes

scientific article

Bisphenol A, obesity, and type 2 diabetes mellitus: genuine concern or unnecessary preoccupation?

scientific article

CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity.

scientific article published on 11 December 2015

Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation

scientific article

Cigarette smoke exposure impairs β-cell function through activation of oxidative stress and ceramide accumulation

scientific article published on 13 March 2020

Circulating Unmethylated Insulin DNA As a Biomarker of Human Beta Cell Death: A Multi-laboratory Assay Comparison

scientific article published on 01 March 2020

Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes

scientific article published on 31 July 2020

Combination Immunotherapy for Type 1 Diabetes

scientific article published on July 2017

Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention

scientific article published on 09 January 2020

Development of insulin-producing cells from primitive biologic precursors

scientific article published on February 2009

Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains

scientific article published on 29 October 2013

Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials.

scientific article

Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes

scientific article

Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes

scientific article published on 6 July 2016

Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell

scientific article published on 12 November 2018

Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review

scientific article published on 4 March 2014

Excess BMI Accelerates Islet Autoimmunity in Older Children and Adolescents

scientific article published on 14 January 2020

Excess BMI in Childhood: A Modifiable Risk Factor for Type 1 Diabetes Development?

scientific article

Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19

scientific article published on 13 November 2020

Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats

scientific article

From immunobiology to β-cell biology: the changing perspective on type 1 diabetes

scientific article

Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets

scientific article

HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression

scientific article

High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling

scientific article published on 29 July 2013

High residual C-peptide likely contributes to glycemic control in type 1 diabetes

scientific article published on 01 April 2020

Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectors

scientific article

Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β-Cell

scientific article published on 21 August 2018

Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α.

scientific article published on 11 February 2017

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

scientific article published on 21 November 2019

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

scientific article

Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes

scientific article

Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling

scientific article

Loss of Diurnal Oscillatory Rhythms in Gut Microbiota Correlates with Changes in Circulating Metabolites in Type 2 Diabetic db/db Mice

scientific article published on 29 September 2019

Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation

scientific article

Metabolic dysfunction and adipose tissue macrophages: is there more to glean from studying the lean?: Comment on "Adipose tissue infiltration in normal-weight subjects and its impact on metabolic function" by Moreno-Indias et al

scientific article published on 3 March 2016

MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells

scientific article published on 9 March 2017

Nucleic acid biomarkers of β cell stress and death in type 1 diabetes

scientific article published on 31 May 2016

PPAR-γ Activation Restores Pancreatic Islet SERCA2 Levels and Prevents β-Cell Dysfunction under Conditions of Hyperglycemic and Cytokine Stress

scientific article published on January 12, 2012

Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway

scientific article

Pancreatic and Islet Development and Function: The Role of Thyroid Hormone.

scientific article

Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell

scientific article

Peroxisome proliferator-activated receptor gamma activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

scientific article

Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes

scientific article published on 24 August 2018

Pre-clinical evaluation of TYK2 inhibitors for human beta cell protection in type 1 diabetes

scientific article published on 01 June 2020

Profiling of RNAs from Human Islet-Derived Exosomes in a Model of Type 1 Diabetes

scientific article published on 25 November 2019

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes

scientific article published on 10 December 2018

Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes

scientific article published on 4 September 2015

Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy

scientific article

Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264

scientific article published on 01 May 2019

Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in Mice

scientific article published on 30 April 2018

Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1.

scientific article

SAT-494 A Very Rare Case: Hypercalcemia Caused by Ectopic PTH Secretion in Endometrial Cancer.

scientific article

SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity

scientific article published on 3 August 2016

SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell

scientific article published on 20 May 2015

STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.

scientific article

Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss

scientific article published on 13 August 2019

Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model

scientific article

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

scientific article published on 15 October 2015

Smoking and the risk of type 2 diabetes

scientific article

Stem Cells as a Tool to Improve Outcomes of Islet Transplantation

scientific article published on August 30, 2012

Streptozotocin is equally diabetogenic whether administered to fed or fasted mice

scientific article published on 10 June 2013

The Effect of Age on the Progression and Severity of Type 1 Diabetes: Potential Effects on Disease Mechanisms

scientific article published on 26 September 2018

The Influence of Type 2 Diabetes-Associated Factors on Type 1 Diabetes

scientific article published on 04 June 2019

The Integrated Islet Distribution Program Answers the Call for Improved Human Islet Phenotyping and Reporting of Human Islet Characteristics in Research Articles

scientific article published on 15 May 2019

The Integrated Islet Distribution Program answers the call for improved human islet phenotyping and reporting of human islet characteristics in research articles

scientific article published on 15 May 2019

The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults

scientific article published on 6 October 2017

The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1.

scientific article published on 24 November 2017

The new Medicare Part D prescription drug benefit: an estimation of its effect on prescription drug costs in a Medicare population with atrial fibrillation

scientific article

The relationship between BMI and insulin resistance and progression from single to multiple autoantibody positivity and type 1 diabetes among TrialNet Pathway to Prevention participants

scientific article published on 19 March 2016

The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening

scientific article published on 25 November 2019

The role of beta-cell dysfunction in early type 1 diabetes

scientific article published on 01 August 2020

The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes

scientific article published on 24 June 2019

Thyroid Hormone Analogues for the Treatment of Metabolic Disorders: New Potential for Unmet Clinical Needs?

scientific article published on November 1, 2012

Translating the results of randomized trials into clinical practice: the challenge of warfarin candidacy among hospitalized elderly patients with atrial fibrillation

scientific article published on 9 March 2006

Translational implications of the β-cell epigenome in diabetes mellitus

scientific article

Type 1 diabetes

scientific article published on 01 June 2018

Urinary biomarkers for the early diagnosis of retinopathy and nephropathy in type 1 diabetes mellitus: a "steady stream" of information using proteomics

scientific article

β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis