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List of works by Irene L Andrulis

10-year performance of four models of breast cancer risk: a validation study

scientific article published on 21 February 2019

11q13 is a susceptibility locus for hormone receptor positive breast cancer

scientific article

19p13.1 is a triple-negative-specific breast cancer susceptibility locus

scientific article published on 13 February 2012

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

scientific article

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

scientific article published on 02 August 2012

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

scientific article

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A comprehensive evaluation of interaction between genetic variants and use of menopausal hormone therapy on mammographic density

scientific article

A genome wide linkage search for breast cancer susceptibility genes

scientific article published on July 2006

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

scientific article

A genome-wide linkage study of mammographic density, a risk factor for breast cancer

scientific article published on 21 December 2011

A high-resolution copy-number variation resource for clinical and population genetics

scientific article published on 11 December 2014

A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium

scientific article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A mutant PTH/PTHrP type I receptor in enchondromatosis

scientific article

A network analysis to identify mediators of germline-driven differences in breast cancer prognosis

scientific article published on 16 January 2020

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

scientific article

A pilot genome-wide association study of early-onset breast cancer

scientific article published on 08 May 2008

A qualitative study evaluating parental attitudes towards the creation of a female youth cohort (LEGACY) in the Breast Cancer Family Registry

scientific article

A role for asparaginyl-tRNA in the regulation of asparagine synthetase in a mammalian cell line ⬇️

scientific article published on June 1, 1977

A role for the TGFbeta-Par6 polarity pathway in breast cancer progression

scientific article

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer

scientific article published on 18 June 2018

ABRAXAS (FAM175A) and Breast Cancer Susceptibility: No Evidence of Association in the Breast Cancer Family Registry

scientific article

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study

scientific article published on July 2007

Aberrant hedgehog signaling and clinical outcome in osteosarcoma

scientific article published on 30 March 2014

Aberrant methylation of RASSF1A in plasma DNA before breast cancer diagnosis in the Breast Cancer Family Registry

scientific article published on 15 September 2009

Abstract 1395: Identification of genes and pathways related to lymphovascular invasion in axillary-node negative breast cancer: A bioinformatic analysis of gene expression data

scientific article published in 2014

Abstract 4593: Genome-wide association study identifies novel loci associated with osteosarcoma

Abstract 5574: High prevalence of germline TP53 mutations in young osteosarcoma cases

Accuracy of Risk Estimates from the iPrevent Breast Cancer Risk Assessment and Management Tool

scientific article published on 19 September 2019

Accuracy of Self-Reported Breast Cancer Information among Women from the Ontario Site of the Breast Cancer Family Registry

scientific article

Accuracy of Self-Reported Screening Mammography Use: Examining Recall among Female Relatives from the Ontario Site of the Breast Cancer Family Registry

scientific article published on August 2013

Adherence to breast and ovarian cancer screening recommendations for female relatives from the Ontario site of the Breast Cancer Family Registry ⬇️

scientific article published on November 1, 2011

Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

scientific article

Age-specific breast cancer risk by body mass index and familial risk: prospective family study cohort (ProF-SC)

Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium

scientific article published on 02 December 2019

Alcohol consumption, cigarette smoking, and familial breast cancer risk: findings from the Prospective Family Study Cohort (ProF-SC)

scientific article published on 28 November 2019

Alcohol metabolism, alcohol intake, and breast cancer risk: a sister-set analysis using the Breast Cancer Family Registry

scientific article published on 01 February 2007

Altered expression and deletion of RMO1 in osteosarcoma

scientific article

Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors

scientific article published on 15 October 2014

Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples

scientific article published in April 2004

An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression

scientific article

An inverse association between ovarian cysts and breast cancer in the breast cancer family registry

scientific article

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

scientific article published on 25 April 2015

Analysis of alterations in the retinoblastoma gene and tumor grade in bone and soft-tissue sarcomas

scientific article published on 01 February 1991

Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

journal article published in 2015

Analysis of incidence and prognostic factors for ipsilateral breast tumour recurrence and its impact on disease-specific survival of women with node-negative breast cancer: a prospective cohort study

scientific article published on January 2006

Analysis of mRNA from Microdissected Frozen Tissue Sections without RNA Isolation ⬇️

scientific article published on July 1, 1998

Application of reliability coefficients in cDNA microarray data analysis

scientific article published in March 2006

Asparaginyl-tRNA aminoacylation levels and asparagine synthetase expression in cultured Chinese hamster ovary cells ⬇️

scientific article published on November 10, 1979

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

scientific article

Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study

scientific article

Assessing patient readiness for personalized genomic medicine.

scientific article published on 26 May 2018

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival

scientific article published on 11 September 2018

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

scientific article

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

scientific article

Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness

scientific article published on 13 November 2019

Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study

scientific article

Association of Prepubertal and Adolescent Androgen Concentrations With Timing of Breast Development and Family History of Breast Cancer

article

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

scientific article

Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21.

scientific article published on 21 October 2016

Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry

scientific article published on 06 April 2016

Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment

scientific article published on 18 August 2021

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

scientific article published on 10 September 2020

Association of tamoxifen use and reduced risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

scientific article published on 12 April 2012

Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival

scholarly article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

scientific article

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

scientific article published on 31 December 2014

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

scientific article published on 18 August 2011

Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis

article by Xiang Shu et al published 1 October 2018 in International Journal of Epidemiology

Atypical protein kinase C zeta: potential player in cell survival and cell migration of ovarian cancer

scientific article

Authors' response: Associations of obesity and circulating insulin and glucose with breast cancer risk

scientific article published on 01 June 2019

BRCA1 and BRCA2 Pathogenic Sequence Variants in Women of African Origin or Ancestry

scientific article published on 03 July 2019

BRCA1 and BRCA2 mutation carriers in the Breast Cancer Family Registry: an open resource for collaborative research

scientific article published on 14 August 2008

BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50.

scientific article

BRCA1 and BRCA2 mutations in Turkish breast/ovarian families and young breast cancer patients

scientific article published on September 2000

BRCA1 and BRCA2 mutations in Turkish familial and non-familial ovarian cancer patients: a high incidence of mutations in non-familial cases

scientific article published on 01 July 2002

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer

scientific article published on 10 March 2017

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

BRCA2 mutation-associated breast cancers exhibit a distinguishing phenotype based on morphology and molecular profiles from tissue microarrays

scientific article

Beliefs about optimal age and screening frequency predict breast screening adherence in a prospective study of female relatives from the Ontario Site of the Breast Cancer Family Registry ⬇️

scientific article published on July 12, 2012

Benign breast disease increases breast cancer risk independent of underlying familial risk profile: Findings from a Prospective Family Study Cohort

scientific article published on 20 February 2019

Biochemical characterization of a mutant asparaginyl-tRNA synthetase from Chinese hamster ovary cells ⬇️

scientific article published on January 10, 1978

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

scientific article published on November 2003

Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in osteosarcoma.

scientific article published on 27 May 2017

Body mass index and breast cancer survival: a Mendelian randomization analysis

scientific article published in December 2017

Breast Cancer Family History and Allele-Specific DNA Methylation in the Legacy Girls Study

scientific article published on 13 February 2018

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

scientific article published on 28 September 2020

Breast Cancer Prognosis inBRCA1andBRCA2Mutation Carriers: An International Prospective Breast Cancer Family Registry Population-Based Cohort Study

article

Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores

scientific article published on 11 January 2022

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2

scientific article

Breast cancer risk for noncarriers of family-specific BRCA1 and BRCA2 mutations: findings from the Breast Cancer Family Registry

scientific article published on 31 October 2011

Breast cancer risk prediction using a polygenic risk score in the familial setting: a prospective study from the Breast Cancer Family Registry and kConFab

scientific article published on 12 May 2016

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Breast carcinomas arising in carriers of mutations in BRCA1 or BRCA2: are they prognostically different?

scientific article

Breast-Cancer Risk in Families With Mutations in PALB2

Breast-cancer risk in families with mutations in PALB2

scientific article

CD10 and CD44 genes of leukemic cells and malignant cell lines show no evidence of transformation-related alterations ⬇️

scientific article published on September 1, 1991

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

scientific article

CK8/18 expression, the basal phenotype, and family history in identifying BRCA1-associated breast cancer in the Ontario site of the breast cancer family registry

scientific article

COPS3 amplification and clinical outcome in osteosarcoma

scientific article published on 01 May 2007

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

scientific article published on 16 December 2019

Cancer Risks Associated With and Pathogenic Variants

scientific article published on 10 May 2022

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Cell cycle regulated phosphorylation of LIMD1 in cell lines and expression in human breast cancers

scientific article

Changes in estrogen receptor, progesterone receptor and Her-2/neu status with time: discordance rates between primary and metastatic breast cancer.

scientific article published on May 2009

Characteristics Associated with Participation at Various Stages at the Ontario Site of the Cooperative Family Registry for Breast Cancer Studies ⬇️

scientific article published on January 1, 2002

Characterization of single step albizziin-resistant Chinese hamster ovary cell lines with elevated levels of asparagine synthetase activity

scientific article published in June 1985

Characterization of the 12q15 MDM2 and 12q13-14 CDK4 amplicons and clinical correlations in osteosarcoma

scientific article published in June 2010

Characterization of the Cancer Spectrum in Men With Germline BRCA1 and BRCA2 Pathogenic Variants: Results From the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 02 July 2020

Chromosomal Alterations Associated with Overproduction of Asparagine Synthetase in Albizziin-Resistant Chinese Hamster Ovary Cells ⬇️

scientific article published on March 1, 1983

Clinical-pathologic significance of cancer stem cell marker expression in familial breast cancers

scientific article published on 28 June 2013

Cloning and mutation analysis of ZFP276 as a candidate tumor suppressor in breast cancer ⬇️

scientific article published on 07 November 2003

Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas

scientific article

Cohort Profile: The Breast Cancer Prospective Family Study Cohort (ProF-SC)

scientific article published on 13 July 2015

Combined associations of a polygenic risk score and classical risk factors with breast cancer risk

scientific article published on 02 May 2020

Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk

scientific article

Combined genetic and splicing analysis of BRCA1 c.[594-2A>C; 641A>G] highlights the relevance of naturally occurring in-frame transcripts for developing disease gene variant classification algorithms

scientific article published on 23 March 2016

Common Childhood Viruses and Pubertal Timing: The LEGACY Girls Study

scientific article published on 31 October 2020

Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 18 May 2011

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

scientific article

Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article published on 2 November 2011

Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk

scientific article published on 27 March 2012

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

scientific article

Common germline polymorphisms associated with breast cancer-specific survival

scientific article published on 22 April 2015

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

scientific article

Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article

Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 20 February 2012

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2009

Common variants in breast cancer risk loci predispose to distinct tumor subtypes

scientific article published on 4 January 2022

Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers

scientific article

Comparing Five-Year and Lifetime Risks of Breast Cancer in the Prospective Family Study Cohort

scientific article published on 10 December 2020

Comparison of 6q25 breast cancer hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article

Comparison of Clinical, Maternal, and Self Pubertal Assessments: Implications for Health Studies

scientific article published on 08 June 2016

Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations

scientific article published on July 2002

Comparison of methods to assess onset of breast development in the LEGACY Girls Study: methodological considerations for studies of breast cancer

scientific article published on 18 April 2018

Comparison of p53 mutations in patients with localized osteosarcoma and metastatic osteosarcoma

scientific article published on 01 October 2001

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer

scientific article

Considerations when using breast cancer risk models for women with negative BRCA1/BRCA2 mutation results

scientific article published on 04 October 2019

Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation

scientific article

Contribution of large genomic BRCA1 alterations to early-onset breast cancer selected for family history and tumour morphology: a report from The Breast Cancer Family Registry

scientific article

Correction to: Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 26 February 2020

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

scholarly article by Mia M Gaudet published in November 2010

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer.

scientific article

Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC)

scientific article published in PLoS ONE

Correction: Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers

scientific article published on 01 January 2019

Correlation of DNA methylation levels in blood and saliva DNA in young girls of the LEGACY Girls study

scientific article

Correlation of p-glycoprotein detection by immunohistochemistry with mdr-1 mRNA levels in osteosarcomas. Pilot study

scientific article published on March 1995

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

DNA methylation patterns associated with asparagine synthetase expression in asparagine-overproducing and -auxotrophic cells

scientific article published on July 1989

DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

scientific article published on 19 December 2013

Detailed deletion mapping with a refined physical map of 7q31 localizes a putative tumor suppressor gene for breast cancer in the region of MET

scientific article published on 01 November 1996

Detectable clonal mosaicism and its relationship to aging and cancer

journal article published in 2012

Detection and typing of human papillomavirus in verrucous carcinoma of the oral cavity using the polymerase chain reaction

scientific article published on 01 December 1993

Diagnostic chest X-rays and breast cancer risk before age 50 years for BRCA1 and BRCA2 mutation carriers

scientific article

Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry

scientific article published on 6 March 2017

Distinguishing luminal breast cancer subtypes by Ki67, progesterone receptor or TP53 status provides prognostic information

scientific article published on 20 September 2013

Does perceived risk predict breast cancer screening use? Findings from a prospective cohort study of female relatives from the Ontario site of the breast cancer family registry

scientific article

E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast

scientific article published on June 2005

EMSY and CCND1 amplification in familial breast cancer: from the Ontario site of the Breast Cancer Family Registry

scientific article published on 15 February 2011

ERβ splice variant expression in four large cohorts of human breast cancer patient tumors

scientific article published on 10 July 2014

EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma.

scientific article

EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma ⬇️

scientific article published on April 1, 1998

Elevated expression of podocalyxin is associated with lymphatic invasion, basal-like phenotype, and clinical outcome in axillary lymph node-negative breast cancer

scientific article

Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis

scientific article

Erratum to: Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

scientific article published on 6 October 2009

Erratum to: PATCHED-ONE or SMOOTHENED Gene Mutations Are Infrequent in Chondrosarcoma

scholarly article published in Clinical Orthopaedics and Related Research

Ethnicity, but not cancer family history, is related to response to a population-based mailed questionnaire

scientific article published in January 2004

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article

Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).

scientific article

Evaluation of associations between genetically predicted circulating protein biomarkers and breast cancer risk

scientific article published on 16 July 2019

Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriers

scientific article

Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers

scientific article published on February 2017

Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

scientific article

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit alpha oncogene and breast cancer risk

scientific article published on 27 October 2011

Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors

scientific article published on 27 March 2013

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

scientific article

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation

scientific article published on 03 September 2016

Expression of insulin-like growth factor receptor, IGF-1, and IGF-2 in primary and metastatic osteosarcoma ⬇️

scientific article published on September 1, 1998

Expression of osteocalcin and its transcriptional regulators core-binding factor alpha 1 and MSX2 in osteoid-forming tumours

scientific article

Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors

scientific article

Expression of the multidrug resistance gene in osteosarcoma: a pilot study.

scientific article

Expression of the multiple drug resistance gene in human renal cell carcinoma depends on tumor histology, grade, and stage.

scientific article published on December 1995

Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

scientific article published on 18 June 2008

FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium

scientific article published on February 2014

Factors affecting distant disease-free survival for primary invasive breast cancer: use of a log-normal survival model

scientific article

Familial posterior fossa brain tumors of infancy secondary to germline mutation of the hSNF5 gene

scientific article

Family history of breast cancer and all-cause mortality after breast cancer diagnosis in the Breast Cancer Family Registry

scientific article

Family-based association study of IGF1 microsatellites and height, weight, and body mass index

scientific article published on 19 March 2010

Family-based genetic association study of insulin-like growth factor I microsatellite markers and premenopausal breast cancer risk

scientific article published on 20 February 2009

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

scientific article published on 07 September 2016

Fine structure analysis of the Chinese hamster AS gene encoding asparagine synthetase

scientific article

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

scientific article

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

scientific article

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

scientific article published on 4 February 2015

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer

scientific article

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk

scientific article

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

scientific article

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

Frequency of p53 mutations in breast carcinomas from Ashkenazi Jewish carriers of BRCA1 mutations

scientific article

Fresh Cut Versus Stored Cut Paraffin-embedded Tissue: Effect on Immunohistochemical Staining for Common Breast Cancer Markers

scientific article published on 01 March 2019

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

scientific article published in July 2021

Functional characterization of novel presenilin-2 variants identified in human breast cancers

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

Gene-based and pathway-based testing for rare-variant association in affected sib pairs

scientific article published on 01 April 2020

Gene-expression patterns in peripheral blood classify familial breast cancer susceptibility

scientific article published on 4 November 2015

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

scientific article

Genetic insights into biological mechanisms governing human ovarian ageing

scientific article

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk

scientific article published on 06 October 2016

Genetic modifiers of menopausal hormone replacement therapy and breast cancer risk: a genome-wide interaction study

scientific article

Genetic predisposition to ductal carcinoma in situ of the breast

scientific article published on 17 February 2016

Genetic predisposition to in situ and invasive lobular carcinoma of the breast

scientific article

Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies

scientific article published on 26 April 2018

Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation

scientific article

Genetic variants of GPX1 and SOD2 and breast cancer risk at the Ontario site of the Breast Cancer Family Registry

scientific article published in January 2004

Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

scientific article

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

scientific article

Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium

scientific article published on 30 November 2015

Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent

scientific article (publication date: August 2016)

Genetically Predicted Levels of DNA Methylation Biomarkers and Breast Cancer Risk: Data From 228 951 Women of European Descent

scientific article published on 01 March 2020

Genome wide screening of CAG trinucleotide repeat lengths in breast cancer

scientific article published on January 2006

Genome-wide association analysis identifies three new breast cancer susceptibility loci

scientific article published on 22 January 2012

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study identifies the GLDC/IL33 locus associated with survival of osteosarcoma patients

scientific article published on 6 December 2017

Genome-wide association study identifies two susceptibility loci for osteosarcoma

scientific article (publication date: July 2013)

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Genome-wide association study of germline variants and breast cancer-specific mortality

scientific article published on 21 February 2019

Genomic alterations in lobular neoplasia: a microarray comparative genomic hybridization signature for early neoplastic proliferationin the breast

scientific article

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Genomics and premalignant breast lesions: clues to the development and progression of lobular breast cancer

scientific article

Germline BRCA2 6174delT mutations in Ashkenazi Jewish pancreatic cancer patients

scientific article published in May 1997

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk

scientific article published on 16 June 2020

Germline TP53 variants and susceptibility to osteosarcoma.

scientific article

Germline Variation and Breast Cancer Incidence: A Gene-Based Association Study and Whole-Genome Prediction of Early-Onset Breast Cancer

article

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

scientific article

Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers.

scientific article

Global DNA methylation levels in girls with and without a family history of breast cancer

scientific article

HER-2/neu status and tumor morphology of invasive breast carcinomas in Ashkenazi women with known BRCA1 mutation status in the Ontario Familial Breast Cancer Registry

scientific article published in November 2002

HER2 and responsiveness of breast cancer to adjuvant chemotherapy.

scientific article

HER2 testing in a population-based study of patients with metastatic breast cancer treated with trastuzumab

scientific article published on 01 January 2008

Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers

scientific article

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

scientific article published on 01 April 2019

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization

scientific article

Heteroduplex and protein truncation analysis of the BRCA1 185delAG mutation

scientific article published on 01 September 1996

Histidyl-tRNA synthetase of Chinese hamster ovary cells contains phosphoserine

scientific article published in January 1986

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape

scientific article published on May 2016

Human subjects protection: an event monitoring committee for research studies of girls from breast cancer families

scientific article

Hypomethylation and reactivation of the asparagine synthetase gene induced by L-asparaginase and ethyl methanesulfonate ⬇️

scientific article published on February 1, 1991

Identification and characterization of missense alterations in the BRCA1 associated RING domain (BARD1) gene in breast and ovarian cancer

scientific article

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

scientific article

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

scientific article published on 27 March 2013

Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site

scientific article

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

Identification of germline alterations of the mad homology 2 domain of SMAD3 and SMAD4 from the Ontario site of the breast cancer family registry (CFR) ⬇️

scientific article published on August 11, 2011

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

scientific article

Identification of new breast cancer predisposition genes via whole exome sequencing

scientific article published on 12 April 2012

Identification of new genetic susceptibility loci for breast cancer through consideration of gene-environment interactions

scientific article

Identification of novel genetic markers of breast cancer survival

scientific article published on 18 April 2015

Identification of rare variants in the hLIMD1 gene in breast cancer

scientific article

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Identifying actionable variants using next generation sequencing in patients with a historical diagnosis of undifferentiated pleomorphic sarcoma.

scientific article published on 10 September 2017

Immuno-transcriptomic profiling of extracranial pediatric solid malignancies

scientific article published on 01 November 2021

Impact of familial risk and mammography screening on prognostic indicators of breast disease among women from the Ontario site of the Breast Cancer Family Registry

scientific article published in June 2014

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33

journal article published in 2014

Incorporating progesterone receptor expression into the PREDICT breast prognostic model

scientific article published in 2022

Increased cancer risks for relatives of very early-onset breast cancer cases with and without BRCA1 and BRCA2 mutations

scientific article

Individual and family characteristics associated with protein truncating BRCA1 and BRCA2 mutations in an Ontario population based series from the Cooperative Family Registry for Breast Cancer Studies

scientific article

Influence of perceived breast cancer risk on screening behaviors of female relatives from the Ontario site of the Breast Cancer Family Registry ⬇️

scientific article published on July 1, 2011

Influence of young age at diagnosis and family history of breast or ovarian cancer on breast cancer outcomes in a population-based cohort study

scientific article published on 18 November 2006

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

scientific article

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer

scientific article

Insights From Mixture Cure Modeling of Molecular Markers for Prognosis in Breast Cancer ⬇️

scientific article published on April 29, 2013

Insulin-like growth factor 1 (IGF-1) receptors, IGF-1, and IGF-2 are expressed in primary human sarcomas.

scientific article published on January 1995

Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility

scientific article published on 10 March 2016

Invasive lobular carcinoma: to grade or not to grade

scientific article published in May 2005

Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors

scientific article

Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma

scientific article published on 21 October 2013

Isolation of human cDNAs for asparagine synthetase and expression in Jensen rat sarcoma cells

scientific article

JAG1 expression is associated with a basal phenotype and recurrence in lymph node-negative breast cancer

scientific article

LAF-4 is aberrantly expressed in human breast cancer

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Limited influence of germline genetic variation on all-cause mortality in women with early onset breast cancer: evidence from gene-based tests, single-marker regression, and whole-genome prediction

scientific article published on 13 May 2017

Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival

scientific article published on 23 July 2021

Low levels of expression of an inhibitor of cyclin-dependent kinases (CIP1/WAF1) in primary breast carcinomas with p53 mutations

scientific article published on 01 August 1995

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

scientific article

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

scientific article

MDR1 gene expression and outcome in osteosarcoma: a prospective, multicenter study

scientific article

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article

Medical radiation exposure and breast cancer risk: findings from the Breast Cancer Family Registry

scientific article published on July 2007

Menacalc, a quantitative method of metastasis assessment, as a prognostic marker for axillary node-negative breast cancer

scientific article published on 27 June 2015

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Mendelian randomisation study of smoking exposure in relation to breast cancer risk

scientific article published in October 2021

Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer

scholarly article

Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer

scientific article published on 18 March 2013

Metabolomic profiles in breast cancer:a pilot case-control study in the breast cancer family registry.

scientific article published on 5 May 2018

Metastatic behavior of the RIF-1 murine fibrosarcoma: inhibited by hypophysectomy and partially restored by growth hormone replacement

scientific article published on 01 April 1994

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens

scientific article

MicroRNA related polymorphisms and breast cancer risk

scientific article

Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes

scientific article

Molecular alterations in bone and soft-tissue sarcoma.

scientific article

Molecular and genetic characterization of human cell lines resistant to L-asparaginase and albizziin

scientific article published on January 1990

Molecular and immunohistochemical identification of p53 alterations in bone and soft tissue sarcomas

scientific article published on 01 January 1996

Molecular genetic changes in musculoskeletal sarcomas.

scientific article published in January 1990

Molecular structure of the human asparagine synthetase gene

scientific article

Molecular variants of the thiazide-sensitive Na+-Cl- cotransporter in hypertensive families

scientific article published in October 2007

Multigene testing of moderate-risk genes: be mindful of the missense

scientific article

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Multiplex PCR-SSCP for simultaneous screening for mutations in several exons of p53

scientific article published on 01 May 1995

Mutation in the coding region of the BRCA1 gene leads to aberrant splicing of the transcript

scientific article published on 01 January 1999

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

scientific article published on 15 February 2018

Mutational analysis of BRCA1 and BRCA2 genes in Chinese ovarian cancer identifies 6 novel germline mutations

scientific article published on 01 July 2000

New Ontario familial breast cancer registry to facilitate genetic and epidemiologic studies

scientific article

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

scientific article published on 29 March 2009

No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study

scientific article published on 04 June 2008

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing

scientific article published on 26 February 2016

No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages <50 years

scientific article

Non-invasive optical spectroscopic monitoring of breast development during puberty

scientific article published on 06 February 2017

Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures

scientific article published on 10 April 2015

Oral contraceptive use and ovarian cancer risk among carriers of BRCA1 or BRCA2 mutations

scientific article published on November 2004

Oral contraceptive use and risk of early-onset breast cancer in carriers and noncarriers of BRCA1 and BRCA2 mutations

scientific article

Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Overexpression of asparagine synthetase in albizziin-resistant murine diploid embryonic stem cells

scientific article published on July 1993

P53 protein accumulation in non-invasive lesions surrounding p53 mutation positive invasive breast cancers

scientific article published in January 2001

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1.

scientific article published on 12 October 2017

Panel sequencing of 264 candidate susceptibility genes and segregation analysis in a cohort of non-BRCA1, non-BRCA2 breast cancer families.

scientific article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

scientific article

Past recreational physical activity, body size, and all-cause mortality following breast cancer diagnosis: results from the Breast Cancer Family Registry

scientific article

Patched-one or smoothened gene mutations are infrequent in chondrosarcoma

scientific article

Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes

scientific article published on 17 March 2022

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium

scientific article published on 03 October 2016

Perceptions of Ashkenazi Jewish breast cancer patients on genetic testing for mutations in BRCA1 and BRCA2.

scientific article published in May 2000

Phase I-II study of vinblastine and oral cyclosporin A in metastatic renal cell carcinoma

scientific article published on 01 June 1995

Phase II study of dexverapamil plus anthracycline in patients with metastatic breast cancer who have progressed on the same anthracycline regimen ⬇️

scientific article published on June 1, 1998

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

scientific article

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

scientific article published on 15 July 2020

Polymorphisms XRCC1-R399Q and XRCC3-T241M and the risk of breast cancer at the Ontario site of the Breast Cancer Family Registry.

scientific article

Polymorphisms cMyc-N11S and p27-V109G and breast cancer risk and prognosis

scientific article

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression

scientific article published on 11 June 2015

Population-based estimates of breast cancer risks associated with ATM gene variants c.7271T>G and c.1066-6T>G (IVS10-6T>G) from the Breast Cancer Family Registry

scientific article published in November 2006

Pre-Pubertal Internalizing Symptoms and Timing of Puberty Onset in Girls

scientific article published on 15 October 2020

Prediagnosis reproductive factors and all-cause mortality for women with breast cancer in the breast cancer family registry

scientific article published on June 2009

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

scientific article

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Preferential allelic expression can lead to reduced expression ofBRCA1 in sporadic breast cancers ⬇️

scientific article published on July 3, 1998

Prognostic effect of basal-like breast cancers is time dependent: evidence from tissue microarray studies on a lymph node-negative cohort

scientific article published on July 2008

Prognostic factors affecting the natural history of node-negative breast cancer

scientific article published in January 2005

Prognostic microRNAs modulate the RHO adhesion pathway: A potential therapeutic target in undifferentiated pleomorphic sarcomas

scientific article published on 23 April 2015

Protein kinase C epsilon and genetic networks in osteosarcoma metastasis

scientific article published on 8 April 2013

Psychosocial Adjustment in School-age Girls With a Family History of Breast Cancer

scientific article published on 19 October 2015

Pubertal development in girls by breast cancer family history: the LEGACY girls cohort

scientific article

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

scientific article published on 10 April 2018

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

scientific article

Quantitative analysis of multidrug resistance gene expression in human osteosarcomas

scientific article

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

scientific article published on 16 October 2007

RAD51 and breast cancer susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry study

scientific article

RAD51B in Familial Breast Cancer

scientific article

RNA expression profiling reveals PRAME, a potential immunotherapy target, is frequently expressed in solitary fibrous tumors

scientific article published on 02 October 2020

Rare germline copy number variants (CNVs) and breast cancer risk

scientific article published on 18 January 2022

Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study

scientific article

Rare mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancers

scientific article

Rare mutations in XRCC2 increase the risk of breast cancer

scientific article (publication date: 6 April 2012)

Rare variants in the ATM gene and risk of breast cancer

scientific article published on 25 July 2011

Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer

scientific article published on 24 September 2009

Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study

scientific article (publication date: 18 January 2011)

Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors

scientific article published in Science

Recreational Physical Activity Is Associated with Reduced Breast Cancer Risk in Adult Women at High Risk for Breast Cancer: A Cohort Study of Women Selected for Familial and Genetic Risk

scientific article published on 02 October 2019

Reduced growth of human sarcoma xenografts in hosts homozygous for the lit mutation

scientific article published on October 2002

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

scientific article

Refined localization of the asparagine synthetase gene (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/KO15.

scientific article published in January 1994

Regression models, scan statistics and reappearance probabilities to detect regions of association between gene expression and copy number

scientific article published on 21 February 2011

Regular use of aspirin and other non-steroidal anti-inflammatory drugs and breast cancer risk for women at familial or genetic risk: a cohort study

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.

scientific article published on 7 November 2017

Reproductive risk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer Family Registry

scientific article published on 18 February 2014

Risk factors for uncommon histologic subtypes of breast cancer using centralized pathology review in the Breast Cancer Family Registry

scientific article published on 25 April 2012

Risk of pancreatic cancer in breast cancer families from the breast cancer family registry

scientific article published on March 2013

Risk-Reducing Oophorectomy and Breast Cancer Risk Across the Spectrum of Familial Risk

scientific article published on 01 March 2019

Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers

scientific article published on 16 January 2020

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

scientific article published on June 2017

SAS is amplified predominantly in surface osteosarcoma

scientific article published on 01 September 1996

SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival

scientific article published on 22 July 2015

SNP-SNP interactions in breast cancer susceptibility

scientific article published on 3 May 2006

Second primary breast cancer in BRCA1 and BRCA2 mutation carriers: 10-year cumulative incidence in the Breast Cancer Family Registry

scientific article

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer

article

Statistical challenges in high-dimensional molecular and genetic epidemiology

scholarly article by Shelley B. Bull et al published 15 November 2017 in Canadian Journal of Statistics

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer

scientific article published on 5 February 2017

TP53Mutations and Outcome in Osteosarcoma: A Prospective, Multicenter Study

scientific article published in March 2005

Tamoxifen and risk of contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

scientific article published on 05 August 2013

The AIB1 Polyglutamine Repeat Does Not Modify Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

article

The APCI1307K allele and breast cancer risk

scientific article

The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity

scientific article published on 20 February 2018

The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer

scientific article

The CHEK2*1100delC allelic variant and risk of breast cancer: screening results from the Breast Cancer Family Registry

scientific article

The Cooperative Familial Registry for Breast Cancer Studies: design and first year recruitment rates in Ontario

scientific article published in January 2001

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

scientific article published on 01 November 2019

The HER-2/neu oncogene in breast cancer: so what is new?

scientific article published on 01 July 1992

The Influence of Number and Timing of Pregnancies on Breast Cancer Risk for Women With or Mutations

The LEGACY Girls Study: Growth and Development in the Context of Breast Cancer Family History

scientific article published on 29 January 2016

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

scientific article published on April 2015

The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article published on 25 August 2009

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation

The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis

scientific article (publication date: 15 May 2006)

The combination of p53 mutation and neu/erbB-2 amplification is associated with poor survival in node-negative breast cancer

scientific article published on 01 January 2004

The genomic landscape of epithelioid sarcoma cell lines and tumours

scientific article published on 14 September 2015

The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors

scientific article

The long non-coding RNA NEAT1 promotes sarcoma metastasis by regulating RNA splicing pathways

scientific article published on 19 June 2020

The potential value of sibling controls compared with population controls for association studies of lifestyle-related risk factors: an example from the Breast Cancer Family Registry

scientific article

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

scientific article published on 8 March 2011

The role of genetic breast cancer susceptibility variants as prognostic factors

scientific article

Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy

scientific article published on 28 April 2009

Topoisomerase II alpha protein and responsiveness of breast cancer to adjuvant chemotherapy with CEF compared to CMF in the NCIC CTG randomized MA.5 adjuvant trial ⬇️

scientific article published on April 26, 2011

Total energy intake and breast cancer risk in sisters: the Breast Cancer Family Registry

scientific article

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

scientific article published on 01 March 2020

Tumoral BRD4 expression in lymph node-negative breast cancer: association with T-bet+ tumor-infiltrating lymphocytes and disease-free survival

scientific article published on 20 July 2018

Tumoral lymphocytic infiltration and expression of the chemokine CXCL10 in breast cancers from the Ontario Familial Breast Cancer Registry

scientific article published on 4 December 2012

Tumour morphology predicts PALB2 germline mutation status

scientific article published on 20 June 2013

Two truncating variants in FANCC and breast cancer risk

scientific article published on 29 August 2019

Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer ⬇️

scientific article published on June 1, 1995

Type of TP53 mutation and ERBB2 amplification affects survival in node-negative breast cancer

scientific article published on 13 January 2007

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry

scientific article published on 11 July 2022

Using cancer registry data: agreement in cause-of-death data between the Ontario Cancer Registry and a longitudinal study of breast cancer patients

scientific article

Validation of Intratumoral T-bet+ Lymphoid Cells as Predictors of Disease-Free Survival in Breast Cancer

scientific article published on 6 November 2015

Validation study of thelambdamodel for predicting theBRCA1orBRCA2mutation carrier status of North American Ashkenazi Jewish women

article

Whole-genome amplification enables accurate genotyping for microarray-based high-density single nucleotide polymorphism array

scientific article

Worry Is Good for Breast Cancer Screening: A Study of Female Relatives from the Ontario Site of the Breast Cancer Family Registry ⬇️

scientific article published on June 28, 2012

hCDC4 variation in osteosarcoma

scientific article published on September 2006

neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group ⬇️

scientific article published on 01 April 1998

p185neu is phosphorylated on tyrosine in human primary breast tumors which overexpress neu/erbB-2

scientific article published on June 1, 1990

p53 missense but not truncation mutations are associated with low levels of p21(CIP1/WAF1) mRNA expression in primary human sarcomas

scientific article published on June 2001

p53 mutations in epithelial ovarian cancers: possible role in predicting chemoresistance.

scientific article

p53 mutations in mammary ductal carcinoma in situ but not in epithelial hyperplasias ⬇️

scientific article published on February 15, 1998

rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk

scientific article

von Willebrand factor expression in osteosarcoma metastasis

scientific article

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