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List of works by Leticia I Llarrull

A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases.

scientific article published on 14 September 2017

Activation of BlaR1 protein of methicillin-resistant Staphylococcus aureus, its proteolytic processing, and recovery from induction of resistance.

scientific article published on 6 September 2011

An experiment-informed signal transduction model for the role of the Staphylococcus aureus MecR1 protein in β-lactam resistance

scientific article published on 20 December 2019

Asp-120 locates Zn2 for optimal metallo-beta-lactamase activity

scientific article

Bisthiazolidines: A Substrate-Mimicking Scaffold as an Inhibitor of the NDM-1 Carbapenemase

scientific article published on 20 July 2015

Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes

scientific article published on 14 June 2016

Crystallization and preliminary X-ray diffraction analysis of the lytic transglycosylase MltE from Escherichia coli ⬇️

scientific article published on December 24, 2010

Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.

scientific article published on 21 February 2014

Dissection of events in the resistance to β-lactam antibiotics mediated by the protein BlaR1 from Staphylococcus aureus.

scientific article published on 29 May 2012

Engineered mononuclear variants in Bacillus cereus metallo-beta-lactamase BcII are inactive.

scientific article published on 25 July 2008

Evidence for a dinuclear active site in the metallo-beta-lactamase BcII with substoichiometric Co(II). A new model for metal uptake

scientific article published on 22 August 2007

Evolution of Metallo-β-lactamases: Trends Revealed by Natural Diversity and in vitro Evolution

scientific article

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

scientific article

Inhibitors for Bacterial Cell-Wall Recycling ⬇️

scientific article published on January 19, 2012

Lysine Nζ-Decarboxylation Switch and Activation of the β-Lactam Sensor Domain of BlaR1 Protein of Methicillin-resistant Staphylococcus aureus ⬇️

scientific article published on July 20, 2011

Metal content and localization during turnover in B. cereus metallo-beta-lactamase

scientific article published on 01 November 2008

Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

scientific article published on 26 May 2009

Overcoming differences: The catalytic mechanism of metallo-β-lactamases

scientific article

Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules

scientific article published on 24 August 2015

Regulation of the expression of the β-lactam antibiotic-resistance determinants in methicillin-resistant Staphylococcus aureus (MRSA).

scientific article published on 03 March 2014

Sulfonate-containing thiiranes as selective gelatinase inhibitors

scientific article

THE REACTION MECHANISM OF METALLO-β-LACTAMASES IS TUNED BY THE CONFORMATION OF AN ACTIVE SITE MOBILE LOOP

scientific article published on 21 December 2018

The future of the β-lactams.

scientific article published on 29 September 2010

X-ray absorption spectroscopy of metal site speciation in the metallo-β-lactamase BcII from Bacillus cereus.

scientific article published on 31 January 2012

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