Search filters

List of works by Carlos Opazo

A novel functional low-density lipoprotein receptor-related protein 6 gene alternative splice variant is associated with Alzheimer's disease.

scientific article published on 06 December 2012

Acetylcholinesterase promotes the aggregation of amyloid-beta-peptide fragments by forming a complex with the growing fibrils.

scientific article published on September 1997

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase

scientific article

Alzheimer's Aβ interacts with cellular prion protein inducing neuronal membrane damage and synaptotoxicity

scientific article published on 16 December 2014

Beta-amyloid causes depletion of synaptic vesicles leading to neurotransmission failure

scientific article

Biphasic effects of copper on neurotransmission in rat hippocampal neurons.

scientific article published in September 2011

Blood and brain protein levels of ubiquitin-conjugating enzyme E2K (UBE2K) are elevated in individuals with schizophrenia

scientific article published on 08 March 2019

Canonical Wnt3a modulates intracellular calcium and enhances excitatory neurotransmission in hippocampal neurons

scientific journal article

Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons.

scientific article published on 3 December 2014

Copper: from neurotransmission to neuroproteostasis

scientific article

Crosslinking of amyloid-beta peptide to brain acetylcholinesterase.

scientific article

Cysteine 144 is a key residue in the copper reduction by the beta-amyloid precursor protein

scientific article published on 01 September 1999

Differential Membrane Toxicity of Amyloid-β Fragments by Pore Forming Mechanisms.

scientific article published on 6 February 2016

Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia

scientific article published on 19 February 2019

Extracellular α-synuclein alters synaptic transmission in brain neurons by perforating the neuronal plasma membrane.

scientific article published on 25 February 2015

Features of alpha-synuclein that could explain the progression and irreversibility of Parkinson's disease

scientific article

Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death

scientific article published on 12 December 2014

Ibuprofen inhibits the synaptic failure induced by the amyloid-β peptide in hippocampal neurons.

scientific article

Intracellular amyloid formation in muscle cells of Abeta-transgenic Caenorhabditis elegans: determinants and physiological role in copper detoxification

scientific article

Low concentrations of ethanol protect against synaptotoxicity induced by Aβ in hippocampal neurons.

scientific article published on 17 October 2014

Metallo-pathways to Alzheimer's disease: lessons from genetic disorders of copper trafficking

scientific article published on 11 July 2016

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

scientific article published on 20 August 2002

Nature of the neurotoxic membrane actions of amyloid-β on hippocampal neurons in Alzheimer's disease.

scientific article published on 8 October 2013

On stage single cell identification of rat spermatogenic cells.

scientific article

Overrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.

scientific article

PSD95 suppresses dendritic arbor development in mature hippocampal neurons by occluding the clustering of NR2B-NMDA receptors.

scientific article

Radioiodinated clioquinol as a biomarker for beta-amyloid: Zn complexes in Alzheimer's disease

scientific article published in February 2006

Rapamycin protects against Aβ-induced synaptotoxicity by increasing presynaptic activity in hippocampal neurons.

scientific article published on 30 April 2014

Soluble Aβ(1-40) peptide increases excitatory neurotransmission and induces epileptiform activity in hippocampal neurons.

scientific article

Stable Complexes Involving Acetylcholinesterase and Amyloid-β Peptide Change the Biochemical Properties of the Enzyme and Increase the Neurotoxicity of Alzheimer’s Fibrils ⬇️

scientific article published on May 1, 1998

Synaptotoxicity of Alzheimer beta amyloid can be explained by its membrane perforating property

scientific article (publication date: 27 July 2010)

The N-terminal copper-binding domain of the amyloid precursor protein protects against Cu2+ neurotoxicity in vivo.

scientific article published on 2 September 2004

The pathophysiology of axonal transport in Alzheimer's disease

scientific article

Wnt/β-catenin signaling stimulates the expression and synaptic clustering of the autism-associated Neuroligin 3 gene

scientific article published on 5 March 2018

Paulina is supported by:

About Paulina

Help