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List of works by Annette Gabriele Beck-Sickinger

99mTc-Labeled Neuropeptide Y Analogues as Potential Tumor Imaging Agents ⬇️

scientific article published on November 1, 2001

A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y2 R Antagonists.

scientific article published on 22 November 2016

A G Protein-biased Designer G Protein-coupled Receptor Useful for Studying the Physiological Relevance of Gq/11-dependent Signaling Pathways.

scientific article published on 5 February 2016

A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture Therapy

scientific article published on 23 December 2019

A Venomics approach coupled to high-throughput toxin production strategies identifies the first venom-derived melanocortin receptor agonists

scientific article published on 30 June 2020

A Y2 receptor mimetic aptamer directed against neuropeptide Y.

scientific article

A cleavable cytolysin-neuropeptide Y bioconjugate enables specific drug delivery and demonstrates intracellular mode of action

scientific article

A novel microfluidic microelectrode chip for a significantly enhanced monitoring of NPY-receptor activation in live mode

scientific article published on 9 November 2017

A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation

scientific article

A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and improves eEPC migration in vitro

scientific article published on 22 May 2012

A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and improves eEPC migration in vitro

scientific article from 2012

A rational approach for the development of reduced‐size analogues of neuropeptide Y with high affinity to the Y1 receptor ⬇️

scientific article published on September 1, 1995

A rationally designed oligopeptide shows significant conformational changes upon binding to sulphate ions ⬇️

scientific article published on December 1, 2001

A reconstitution protocol for the in vitro folded human G protein-coupled Y2 receptor into lipid environment

scientific article published on 8 April 2010

A stable meta -carborane enables the generation of boron-rich peptide agonists targeting the ghrelin receptor

scientific article published on 31 August 2018

Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization

scientific article published on 10 June 2010

Active contractions in single suspended epithelial cells.

scientific article published on 7 November 2013

Adiponectin promotes the migration of circulating angiogenic cells through p38-mediated induction of the CXCR4 receptor

scientific article published on 07 June 2012

Adiponectin receptor 1 interacts with both subunits of protein kinase CK2.

scientific article

Adrenomedullin - Current Perspective on a Peptide Hormone with Significant Therapeutic Potential

scientific article published on 19 June 2020

Adrenomedullin - new perspectives of a potent peptide hormone

scientific article published on 2 February 2017

Adrenomedullin 2.0: Adjusting Key Levers for Metabolic Stability

scientific article published on 10 May 2016

Adrenomedullin disulfide bond mimetics uncover structural requirements for AM1 receptor activation

scientific article published on 24 January 2019

Advanced 96-microtiter plate based bioelectrochemical platform reveals molecular short cut of electron flow in cytochrome P450 enzyme

scientific article published on 27 March 2020

Agonist induced receptor internalization of neuropeptide Y receptor subtypes depends on third intracellular loop and C-terminus

scientific article published on 8 June 2008

Agonists for neuropeptide Y receptors Y1 and Y5 stimulate different phases of feeding in guinea pigs

scientific article

Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor.

scientific article published on June 2002

An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins

scientific article published on 11 February 2020

An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor

scientific article published on 05 September 2012

Analogues of Neuropeptide Y Containing β-Aminocyclopropane Carboxylic Acids are the Shortest Linear Peptides That Are Selective for the Y1 Receptor

scholarly article by Norman Koglin et al published 13 January 2003 in Angewandte Chemie International Edition

Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels

scientific article published on 12 June 2013

Anchor‐linked intermediates in peptide amide synthesis are caused by dimeric anchors on the solid supports ⬇️

scientific article published on 01 May 1995

Anti-Inflammatory Action of Keratinocyte-Derived Vaspin: Relevance for the Pathogenesis of Psoriasis

scientific article published on 10 January 2016

Artificial chemokines: combining chemistry and molecular biology for the elucidation of interleukin-8 functionality

scientific article

Asborin inhibits Aldo/Keto reductase 1A1.

scientific article published in January 2011

Assessment of a fully active class A G protein-coupled receptor isolated from in vitro folding

scientific article published on 20 October 2011

Automated solid-phase peptide synthesis to obtain therapeutic peptides

scientific article

Back Cover: Charge-Compensated Metallacarborane Building Blocks for Conjugation with Peptides (ChemBioChem 4/2016)

scholarly article by René Frank et al published February 2016 in ChemBioChem

Biased agonists at the human Y1 receptor lead to prolonged membrane residency and extended receptor G protein interaction

scientific article published on 09 January 2020

Bilayer interaction and localization of cell penetrating peptides with model membranes: a comparative study of a human calcitonin (hCT)-derived peptide with pVEC and pAntp(43-58).

scientific article published in June 2005

Biochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus.

scientific article

Biocompatible silicon surfaces through orthogonal click chemistries and a high affinity silicon oxide binding peptide

scientific article

Bioorthogonal Labeling of Ghrelin Receptor to Facilitate Studies of Ligand-Dependent Conformational Dynamics

scientific article published on 3 November 2015

Blockade of neuropeptide Y(2) receptors and suppression of NPY's anti-epileptic actions in the rat hippocampal slice by BIIE0246

scientific journal article

Breast-cancer diagnosis by neuropeptide Y analogues: from synthesis to clinical application

scientific article

C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment

scientific article published on 3 November 2016

C-terminus of a hexapeptidic ghrelin receptor inverse agonist can switch peptide behavior from inverse agonism to agonism

scientific article published on 01 January 2016

Calcitonin-derived carrier peptide plays a major role in the membrane localization of a peptide-cargo complex

scientific article

Calcitonin-derived peptide carriers: mechanisms and application

scientific article

Carbaboranes – more than just phenyl mimetics

Carbaboranylation of Truncated C-Terminal Neuropeptide Y Analogue Leads to Full hY1 Receptor Agonism

scientific article published on 25 September 2018

Cell-Free Expression and Photo-Crosslinking of the Human Neuropeptide Y Receptor

Cellular internalization of enhanced green fluorescent protein ligated to a human calcitonin-based carrier peptide

scientific article

Cellular internalization of human calcitonin derived peptides in MDCK monolayers: a comparative study with Tat(47-57) and penetratin(43-58).

scientific article

Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and Tat(47-57) through well-differentiated epithelial models

scientific article published in July 2004

Central NPY receptor-mediated alteration of heart rate dynamics in mice during expression of fear conditioned to an auditory cue.

scientific article

Central nervous system neuropeptide Y regulates mediators of hepatic phospholipid remodeling and very low-density lipoprotein triglyceride secretion via sympathetic innervation

scientific article

Central nervous system neuropeptide Y signaling via the Y1 receptor partially dissociates feeding behavior from lipoprotein metabolism in lean rats

scientific article

Characterisation of Neuropeptide Y Receptor Subtypes by Synthetic NPY Analogues and by Anti-receptor Antibodies‡.

scientific article published on 30 April 2001

Characterization of a new neuropeptide Y Y5 agonist radioligand: [125I][cPP(1-7), NPY(19-23), Ala31, Aib32, Gln34]hPP.

scientific article published on August 2004

Characterization of the interaction of interleukin-8 with hyaluronan, chondroitin sulfate, dermatan sulfate and their sulfated derivatives by spectroscopy and molecular modeling

scientific article published on 26 August 2011

Charge-Compensated Metallacarborane Building Blocks for Conjugation with Peptides.

scientific article published on 10 December 2015

Chemerin and vaspin: possible targets to treat obesity?

scientific article

Chemical and biological characterization of new Re(CO)3/[99mTc](CO)3 bombesin analogues

scientific article published on 28 November 2006

Chemical modification of neuropeptide Y for human Y1 receptor targeting in health and disease

scientific article published on 01 February 2019

Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes

scientific article published on 01 December 2021

Cluster properties of peptides on (100) semiconductor surfaces

scientific article published in September 2006

Comparative analysis of the signaling capabilities of the insulin receptor-related receptor

scientific article

Comparison of the photochemical behavior of four different photoactivatable probes ⬇️

scientific article published on 01 May 1997

Conformation and Aggregation of Selectively PEGylated and Lipidated Gastric Peptide Hormone Human PYY

Conformation and Aggregation of Selectively PEGylated and Lipidated Gastric Peptide Hormone Human PYY3–36

scientific article published on 19 September 2018

Controlling toxicity of Peptide-drug conjugates by different chemical linker structures

scientific article published on 9 April 2015

Corrigendum to "Short-range cytokine gradients to mimic paracrine cell interactions in vitro" [J. Control. Release 224 (2016) 59-68]

scientific article published on 27 September 2016

Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape

scientific article

Design, evaluation, and comparison of ghrelin receptor agonists and inverse agonists as suitable radiotracers for PET imaging

scientific article published on 20 March 2012

Design, synthesis, and biological evaluation of a multifunctional neuropeptide-Y conjugate for selective nuclear delivery of radiolanthanides

scientific article published on 02 March 2020

Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence

scientific article

Developing novel hCT derived cell-penetrating peptides with improved metabolic stability

scientific article published on 15 November 2005

Development and characterization of a highly selective neuropeptide Y Y5 receptor agonist radioligand: [125I][hPP1-17, Ala31, Aib32]NPY.

scientific article published in August 2003

Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging.

scientific article published on 05 April 2017

Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential.

scientific article

Different mode of arrestin-3 binding at the human Y1 and Y2 receptor

scientific article published on 23 June 2018

Dimerization of adiponectin receptor 1 is inhibited by adiponectin

scientific article published on 23 March 2010

Discovery of Small-Molecule Modulators of the Human Y4 Receptor

scientific article

Double Methotrexate-Modified Neuropeptide Y Analogues Express Increased Toxicity and Overcome Drug Resistance in Breast Cancer Cells

scientific article

Drug delivery and release systems for targeted tumor therapy

scientific article

Effect of neuropeptide Y on inflammatory paw edema in the rat: involvement of peripheral NPY Y1 and Y5 receptors and interaction with dipeptidyl-peptidase IV (CD26)

scientific journal article

Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery

scientific article

Electron paramagnetic resonance backbone dynamics studies on spin-labelled neuropeptide Y analogues

scientific article published in December 2002

Endothelialization of Titanium Surfaces by Bioinspired Cell Adhesion Peptide Coatings

scientific article published on 30 September 2019

Energetic electron assisted synthesis of highly tunable temperature-responsive collagen/elastin gels for cyclic actuation: macroscopic switching and molecular origins

scientific article published on 26 August 2019

Epitope mapping: synthetic approaches to the understanding of molecular recognition in the immune system ⬇️

scientific article published on January 1, 1993

Expressed enzymatic ligation for the semisynthesis of chemically modified proteins

scientific article published in October 2003

Expressed protein ligation for protein semisynthesis and engineering.

scientific article

Expressed protein ligation to obtain selectively modified aldo/keto reductases

scientific article

Expressed protein ligation. Method and applications

scientific article published on February 2004

Expression, Functional Characterization, and Solid-State NMR Investigation of the G Protein-Coupled GHS Receptor in Bilayer Membranes

scientific article published on 7 April 2017

Facile and selective nanoscale labeling of peptides in solution by using photolabile protecting groups

scientific article published in October 2003

First selective agonist of the neuropeptide Y1-receptor with reduced size

scientific article

Fluorescence resonance energy transfer to study receptor dimerization in living cells

scientific article published in January 2004

Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands.

scientific article published on 8 September 2006

Fluorescently labeled adrenomedullin allows real-time monitoring of adrenomedullin receptor trafficking in living cells

scientific article published on 01 December 2015

From Micromolar to Nanomolar Affinity: A Systematic Approach To Identify the Binding Site of CGRP at the Human Calcitonin Gene-Related Peptide 1 Receptor ⬇️

scientific article published on 01 January 1998

From Scientists to Scientists-Moving Angewandte into the Future

scientific article published on 25 June 2020

From transcription profile to expression: the signaling repertoire of the SK-N-MC neuroepithelioma cell-line

scientific article

Functional role of the extracellular N-terminal domain of neuropeptide Y subfamily receptors in membrane integration and agonist-stimulated internalization

scientific article published on 22 September 2008

G protein pre-assembly rescues efficacy of W6.48 toggle mutations in neuropeptide Y2 receptor.

scientific article published on 7 February 2018

GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system.

scientific article published on 6 May 2008

GPR39 signaling is stimulated by zinc ions but not by obestatin

scientific article

Generation of carrier peptides for the delivery of nucleic acid drugs in primary cells

scientific article published on February 2008

Genetically Encoded Photocrosslinkers as Molecular Probes To Study G‐Protein‐Coupled Receptors (GPCRs) ⬇️

scientific article published on November 30, 2011

Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor

scientific article published on 23 June 2006

Ghrelin receptor: high constitutive activity and methods for developing inverse agonists

scientific article

Ghrelin--a novel generation of anti-obesity drug: design, pharmacomodulation and biological activity of ghrelin analogues

scientific article

Glutamate release by neurons evokes a purinergic inhibitory mechanism of osmotic glial cell swelling in the rat retina: activation by neuropeptide Y.

scientific article published in March 2006

Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist.

scientific article

Half-Life Extending Modifications of Peptide YY3-36 Direct Receptor-Mediated Internalization

scientific article published on 25 July 2019

High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry

scientific article published on 10 December 2014

Highlight: protein states with cell biological and medicinal relevance

scientific article published in August 2013

Homodimerization of neuropeptide y receptors investigated by fluorescence resonance energy transfer in living cells

scientific article published on 10 January 2003

Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator

scientific article published on 10 August 2017

Identification and stabilization of a highly selective gastrin-releasing peptide receptor agonist

scientific article published on 19 November 2019

Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity

scientific article published on 19 November 2020

Identification of a potential modification site in human stromal cell-derived factor-1.

scientific article published in January 2010

Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism

scientific article published on 19 March 2007

Identification of neuropeptide Y cleavage products in human blood to improve metabolic stability

scientific article published in January 2007

Identification of the Key Residue of Calcitonin Gene Related Peptide (CGRP) 27−37 to Obtain Antagonists with Picomolar Affinity at the CGRP Receptor

article

Identification of the dimerisation interface of human interleukin-8 by IL-8-variants containing the photoactivatable amino acid benzoyl-phenylalanine

scientific article published on 6 October 2006

Illuminating the Path to Enhanced Bioimaging by Phosphole‐based Fluorophores

scientific article published on 8 February 2024

Illuminating the life of GPCRs

scientific article published on 14 July 2009

Improved in Vitro Folding of the Y2 G Protein-Coupled Receptor into Bicelles

scientific article published in January 2017

Improving the tumor uptake of 99mTc-labeled neuropeptides using stabilized peptide analogues

scientific article

In vitro and in vivo evaluation of a 99mTc(I)-labeled bombesin analogue for imaging of gastrin releasing peptide receptor-positive tumors

scientific article published on 01 July 2002

In vitro gene delivery by a novel human calcitonin (hCT)-derived carrier peptide

scientific article published on January 2004

In vitro modification of substituted cysteines as tool to study receptor functionality and structure-activity relationships

scientific article published on 25 April 2013

In vivo characterization of high Basal signaling from the ghrelin receptor

scientific article published on 9 October 2009

Incorporation of ortho-carbaboranyl-Nε-modified L-lysine into neuropeptide Y receptor Y1- and Y2-selective analogues

scientific article published on 11 March 2011

Inhibition of Kallikrein-Related Peptidases 7 and 5 by Grafting Serpin Reactive-Center Loop Sequences onto Sunflower Trypsin Inhibitor-1 (SFTI-1)

scientific article published on 22 December 2015

Integrating solid-state NMR and computational modeling to investigate the structure and dynamics of membrane-associated ghrelin

scientific article

Interactions of the human calcitonin fragment 9-32 with phospholipids: a monolayer study

scientific article

Intracellular Trafficking of Neuropeptide Y Receptors

scientific article published on 25 March 2015

Investigation of lysine side chain interactions of interleukin-8 with heparin and other glycosaminoglycans studied by a methylation-NMR approach.

scientific article published on 27 August 2013

Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex

scientific article

Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY

scientific article

Large scale modification of biomolecules using immobilized sortase A from Staphylococcus aureus

scientific article published in April 2013

Ligand-binding and -scavenging of the chemerin receptor GPR1

scientific article published on 09 July 2021

Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail

scientific article

Ligand-mimicking receptor variant discloses binding and activation mode of prolactin-releasing peptide

scientific article

Live cell PNA labelling enables erasable fluorescence imaging of membrane proteins

scientific article published on 07 December 2020

Localization of novel adiponectin receptor constructs.

scientific article published on January 2006

Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation

scientific article

Matrix metalloproteinase 9 (MMP-9) mediated release of MMP-9 resistant stromal cell-derived factor 1α (SDF-1α) from surface modified polymer films

scientific article published on April 2014

Membrane interaction of neuropeptide Y detected by EPR and NMR spectroscopy

scientific article published in August 2005

Membrane surface-associated helices promote lipid interactions and cellular uptake of human calcitonin-derived cell penetrating peptides

scientific article published on 23 September 2005

Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58)

scientific article

Microelectrode chip based real time monitoring of vital MCF-7 mamma carcinoma cells by impedance spectroscopy

scientific article

Microscopic mechanism of specific peptide adhesion to semiconductor substrates

scientific article published on December 2010

Modular triazine-based carborane-containing carboxylic acids - synthesis and characterisation of potential boron neutron capture therapy agents made of readily accessible building blocks

scientific article published on 27 June 2019

Modulation of Human CXCL12 Binding Properties to Glycosaminoglycans To Enhance Chemotactic Gradients

scientific article from 2019

Molecular ligand-receptor interaction of the NPY/PP peptide family

scientific article

Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors.

scientific article published on September 2010

Molecular recognition of the NPY hormone family by their receptors

scientific article

Molecular tools to characterize adiponectin activity

scientific article published on January 2012

Multifunctional Coating Improves Cell Adhesion on Titanium by using Cooperatively Acting Peptides

scholarly article by Mareen Pagel et al published 3 March 2016 in Angewandte Chemie International Edition

Multifunctional biomaterial coatings: synthetic challenges and biological activity.

scientific article published on 16 September 2016

Multifunctional coatings combining bioactive peptides and affinity-based cytokine delivery for enhanced integration of degradable vascular grafts

scientific article published on 01 March 2020

Multifunktionale Beschichtung verbessert Zelladhäsion auf Titan durch kooperativ wirkende Peptide

Multiple NPY receptors Inhibit GABA(A) synaptic responses of rat medial parvocellular effector neurons in the hypothalamic paraventricular nucleus

scientific journal article

Multiple Peptide Synthesis to Identify Bioactive Hormone Structures

Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes

scientific article published on 29 March 2014

NPY modulates epinephrine-induced leukocytosis via Y-1 and Y-5 receptor activation in vivo: sympathetic co-transmission during leukocyte mobilization

scientific article published in November 2002

NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

scientific article published on 16 November 2019

Nano-high-performance liquid chromatography in combination with nano-electrospray ionization Fourier transform ion-cyclotron resonance mass spectrometry for proteome analysis

scientific article published in January 2003

Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo.

scientific article published in October 2003

Neuropeptide Y and its receptor subtypes specifically modulate rat peritoneal macrophage functions in vitro: counter regulation through Y1 and Y2/5 receptors

scientific article published on 01 January 2005

Neuropeptide Y as a risk factor for cardiorenal disease and cognitive dysfunction in chronic kidney disease: translational opportunities and challenges

scientific article published on 9 December 2021

Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells

scientific article

Neuropeptide Y receptors: how to get subtype selectivity

scientific article published on 04 February 2013

Neuropeptide Y receptors: ligand binding and trafficking suggest novel approaches in drug development

scientific article published on 24 February 2011

Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus

scientific article published in May 2005

Neuropeptide Y suppresses absence seizures in a genetic rat model primarily through effects on Y receptors

scientific article published on 01 February 2007

Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis

scientific journal article

New Boron Delivery Agents

scientific article published in April 2023

Novel Y2-selective, reduced-size agonists of neuropeptide Y ⬇️

scholarly article

Novel cell line selectively expressing neuropeptide Y-Y2 receptors

scientific article published on January 2003

Novel chemically modified analogues of neuropeptide Y for tumor targeting

scientific article

Novel daunorubicin-carrier peptide conjugates derived from human calcitonin segments

scholarly article by Ulrike Krauss published in January 2003

Novel modified and radiolabelled neuropeptide Y analogues to study Y-receptor subtypes

scientific article published in August 2004

On-Resin Synthesis of an Acylated and Fluorescence-Labeled Cyclic Integrin Ligand for Modification of Poly(lactic-co-glycolic acid)

scientific article published on 01 November 2012

On-resin Diels-Alder reaction with inverse electron demand: an efficient ligation method for complex peptides with a varying spacer to optimize cell adhesion

scientific article

One-step procedure for staining of proteins with ruthenium II tris (bathophenanthroline disulfonate)

scientific article published on 20 November 2006

Oxidative in vitro folding of a cysteine deficient variant of the G protein-coupled neuropeptide Y receptor type 2 improves stability at high concentration

scientific article published in August 2013

Palmitoylated SDF1 α Shows Increased Resistance against Proteolytic Degradation in Liver Homogenates ⬇️

scientific article published on January 3, 2011

Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.

scientific article published on 27 December 2013

Peptide backbone conformation affects the substrate preference of protein arginine methyltransferase I.

scientific article published on 27 June 2012

Peptide chemistry toolbox - Transforming natural peptides into peptide therapeutics

scientific article published on 29 January 2018

Peptide drugs to target G protein-coupled receptors

scientific article published on 23 July 2010

Peptide mini-scaffold facilitates JNK3 activation in cells

scientific article published on 12 February 2016

Peptide modifications differentially alter G protein-coupled receptor internalization and signaling bias

scientific article published on 25 July 2014

Peptide-Drug Conjugates and Their Targets in Advanced Cancer Therapies

scientific article published on 07 July 2020

Peptide-Mediated Specific Immobilization of Catalytically Active Cytochrome P450 BM3 Variant

scientific article

Peptide-mediated surface coatings for the release of wound-healing cytokines

scientific article published on 06 September 2020

Peptide-tags for site-specific protein labelling in vitro and in vivo

scientific article published on 10 March 2016

Peptide-templated acyl transfer: a chemical method for the labeling of membrane proteins on live cells

scientific article published on 31 July 2014

Peptides and peptide conjugates: therapeutics on the upward path

scientific article published on August 2012

Photoactivatable chemokines--controlling protein activity by light

scientific article published on 6 June 2013

Position and length of fatty acids strongly affect receptor selectivity pattern of human pancreatic polypeptide analogues

scientific article

Preparation of C-terminally Modified Chemokines by Expressed Protein Ligation ⬇️

scientific article published on January 1, 2013

Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium

scientific article published in March 2003

Probing of the neuropeptide Y−Y1‐receptors interaction with anti‐receptor antibodies ⬇️

scientific article published on August 1, 1998

Probing the Y2 Receptor on Transmembrane, Intra- and Extra-Cellular Sites for EPR Measurements

scientific article published on 10 September 2020

Processing, signaling, and physiological function of chemerin

scientific article

Prokaryotic expression, in vitro folding, and molecular pharmacological characterization of the neuropeptide Y receptor type 2.

scientific article

Proliferative effect of calcitonin gene-related peptide is induced by at least five proteins as identified by proteome profiling

scientific article published on January 2007

Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior

scientific article

Protein kinase CK2 interacts with adiponectin receptor 1 and participates in adiponectin signaling

scientific article

Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement

scientific article

Proteome analysis to study signal transduction of G protein-coupled receptors

scientific article

Pyridone dipeptide backbone scan to elucidate structural properties of a flexible peptide segment

scientific article published on 05 June 2008

Quality assurance in computer validation systems postgraduate seminar on quality assurance in the pharmaceutical industry

scholarly article

Quantitative impedimetric NPY-receptor activation monitoring and signal pathway profiling in living cells

scientific article

RFamide Peptides: Structure, Function, Mechanisms and Pharmaceutical Potential

Rapid Covalent Fluorescence Labeling of Membrane Proteins on Live Cells via Coiled-Coil Templated Acyl Transfer

scientific article published on 14 September 2015

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight

scientific article published on 7 May 2015

Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.

scientific article published on 4 January 2007

Receptor-mediated uptake of boron-rich neuropeptide y analogues for boron neutron capture therapy

scientific article published on 22 October 2014

Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors

scientific article published on 04 May 2022

Recombinant expression and characterization of biologically active protein delta homolog 1.

scientific article published on 15 February 2015

Research and development of vaccines and pharmaceuticals from biotechnology — A guide to effective project management, patenting and product registration

scholarly article

Residue 75 of interleukin-8 is crucial for its interactions with glycosaminoglycans

scientific article published on 15 October 2012

Role of Prohormone Convertases in Pro-Neuropeptide Y Processing: Coexpression and in Vitro Kinetic Investigations ⬇️

scientific article published on December 23, 1997

Selective Neuropeptide Y Conjugates with Maximized Carborane Loading as Promising Boron Delivery Agents for Boron Neutron Capture Therapy

scientific article published on 22 October 2019

Selective labelling of stromal cell-derived factor 1α with carboxyfluorescein to study receptor internalisation

scientific article published on October 2010

Selective mode of action of guanidine-containing non-peptides at human NPFF receptors

scientific article published on 26 June 2012

Semi-synthesis of chemokines

scientific article

Semisynthesis and application of carboxyfluorescein-labelled biologically active human interleukin-8.

scientific article published in December 2003

Semisynthesis and characterization of the first analogues of pro-neuropeptide y.

scientific article published in May 2003

Short-range cytokine gradients to mimic paracrine cell interactions in vitro

scientific article published on 4 January 2016

Shuttling of Peptide-Drug Conjugates by G Protein-coupled Receptors is Significantly Improved by Pulsed Application

scientific article published on 22 July 2020

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation

scientific article

Simultaneous "one pot" expressed protein ligation and CuI-catalyzed azide/alkyne cycloaddition for protein immobilization

scientific article published on 8 September 2011

Slime protein profiling: a non-invasive tool for species identification in Onychophora (velvet worms)

article

Specifically immobilised aldo/keto reductase AKR1A1 shows a dramatic increase in activity relative to the randomly immobilised enzyme

scientific article published on 01 June 2007

Strategies for Site-Specific Labeling of Receptor Proteins on the Surfaces of Living Cells by Using Genetically Encoded Peptide Tags

scientific article

Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding

scientific article published on 01 June 2005

Structural Model of Ghrelin Bound to its G Protein-Coupled Receptor

scientific article published on 24 January 2019

Structural basis for ligand recognition of the neuropeptide Y Y<sub>2</sub> receptor

scientific article published on 02 February 2021

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor

scientific article published on 18 April 2018

Structural investigations of a human calcitonin-derived carrier peptide in a membrane environment by solid-state NMR.

scientific article published in October 2004

Structural investigations of cell-free expressed G protein-coupled receptors

scientific article published on 01 December 2019

Structural properties of orexins for activation of their receptors.

scientific article published in April 2006

Structure and Dynamics of Helix-0 of the N-BAR Domain in Lipid Micelles and Bilayers

scientific article

Structure-activity relationship studies: methods and ligand design for G-protein coupled peptide receptors

scientific article published on August 2006

Structure-activity studies of RFamide peptides reveal subtype-selective activation of neuropeptide FF1 and FF2 receptors

scientific article published on 04 May 2011

Structure-activity studies of orexin a and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligands

scientific article published on February 2004

Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide

scientific article published on 24 September 2021

Structure–activity relationships with neuropeptide Y analogues: a comparison of human Y1-, Y2- and rat Y2-like systems ⬇️

scientific article published on September 25, 1998

Sulfated hyaluronan attenuates inflammatory signaling pathways in macrophages involving induction of antioxidants

scientific article published on 24 March 2017

Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG-protein binding

scientific article published on 01 November 2018

Synthesis and application of peptides as drug carriers

scientific article published in January 2009

Synthesis and in vitro and in vivo evaluation of an (18)F-labeled neuropeptide Y analogue for imaging of breast cancer by PET.

scientific article published on 13 March 2015

Synthetic S‐(2,3‐dihydroxypropyl)‐cysteinyl peptides derived from the N‐terminus of the cytochrome subunit of the photoreaction centre of Rhodopseudomonas viridis enhance murine splenocyte proliferation ⬇️

scientific article published on 01 May 1995

Targeted tumor diagnosis and therapy with peptide hormones as radiopharmaceuticals

scientific article published on February 2008

Tetrafunctional photoaffinity labels based on Nakanishi's m-nitroalkoxy-substituted phenyltrifluoromethyldiazirine

scientific article published on 01 July 2002

The Bioactive Conformation of Neuropeptide Y Analogues at the Human Y2‐Receptor ⬇️

scientific article published on 01 August 1997

The Conformational Equilibrium of the Neuropeptide Y2 Receptor in Bilayer Membranes

scientific article published on 13 August 2020

The Dynamics of the Neuropeptide Y Receptor Type 1 Investigated by Solid-State NMR and Molecular Dynamics Simulation

scientific article published on 24 November 2020

The Impact of Adrenomedullin Thr22 on Selectivity within the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein System

scientific article published on 31 July 2018

The SK-N-MC cell line expresses an orexin binding site different from recombinant orexin 1-type receptor

scientific article (publication date: February 2002)

The Wealth of Cytomics. Résumé of the 19th Annual Meeting of the German Society for Cytometry (Deutsche Gesellschaft Für Zytometrie, DGfZ).

scientific article published in September 2010

The activity of prolactin releasing peptide correlates with its helicity

scientific article

The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion

scientific article

The anterograde transport of the human neuropeptide Y2 receptor is regulated by a subtype specific mechanism mediated by the C-terminus

scientific article published on 26 September 2012

The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors

scientific journal article

The effect of interleukin-8 truncations on its interactions with glycosaminoglycans

scientific article

The first reporter gene assay on living cells: green fluorescent protein as reporter gene for the investigation of Gi-protein coupled receptors

scientific article published in May 2002

The interaction of neuropeptide Y with negatively charged and zwitterionic phospholipid membranes

scientific article published on 25 March 2009

The neuropeptide Y monomer in solution is not folded in the pancreatic-polypeptide fold

scientific article

The structural investigation of glycosaminoglycan binding to CXCL12 displays distinct interaction sites

scientific article published on 24 June 2016

The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor.

scientific article published on 23 September 2008

Time-Resolved Tracking of Separately Internalized Neuropeptide Y2 Receptors by Two-Color Pulse-Chase.

scientific article published on 21 December 2017

Toward the application of proteomics to human thyroid tissue

scientific article published on 01 November 2006

Towards improved receptor targeting: anterograde transport, internalization and postendocytic trafficking of neuropeptide Y receptors

scientific article published on August 2013

Towards understanding the free and receptor bound conformation of neuropeptide Y by fluorescence resonance energy transfer studies

scientific article

Tracking of human Y receptors in living cells--a fluorescence approach

scientific article published on 4 January 2007

Tuning a modular system - synthesis and characterisation of a boron-rich s-triazine-based carboxylic acid and amine bearing a galactopyranosyl moiety

scientific article published on 06 December 2019

Tuning peptide affinity for biofunctionalized surfaces ⬇️

scientific article published on February 27, 2013

Two motifs with different function regulate the anterograde transport of the adiponectin receptor 1.

scientific article

Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively.

scientific article published on 21 January 2009

Ubiquitin is a versatile scaffold protein for the generation of molecules with de novo binding and advantageous drug-like properties

scientific article

Unique interaction pattern for a functionally biased ghrelin receptor agonist

scientific article published on 14 March 2011

Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state

scientific article published on 30 March 2020

Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y₂ Receptor Binding and Activation

scientific article published on 29 April 2015

Vaspin inhibits kallikrein 7 by serpin mechanism

scientific article

Vaspin--a link of obesity and psoriasis?

scientific article published on 01 April 2012

Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine

scientific article published on July 2008

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