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List of works by Christophe Broca

Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells

scientific article published in June 2014

Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets

scientific article published on 17 February 2009

ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival

scientific article published on August 2006

GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells

scientific journal article

Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.

scientific article published on 21 January 2016

Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat.

scientific article published on 13 April 2004

Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion

scientific article

Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped

scientific article published in 2022

Proteasomal degradation of the histone acetyl transferase p300 contributes to beta-cell injury in a diabetes environment.

scientific article published on 22 May 2018

Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets

scientific article

Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes

scientific article published on 01 June 2019

beta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells

scientific article

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