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List of works by Joseph Loscalzo

5-Lipoxygenase and human pulmonary artery endothelial cell proliferation ⬇️

scientific article published on February 1, 2002

A Breath-Taking Diagnosis

scientific article published on 01 January 2019

A Dangerous Detour

scientific article published on 01 March 2019

A Dangerous Detour

scientific article published on 01 April 2019

A Disturbing Decline

scientific article published on 01 June 2019

A Headache of a Diagnosis

scientific article published on 01 August 2018

A Rapid Change in Pressure

scientific article published on 01 February 2020

A Shocking Development in a Young Male Athlete With Chest Pain

scientific article published on 01 February 2016

A Shocking Turn of Events

scientific article published on 01 June 2018

A Systems Approach to Refine Disease Taxonomy by Integrating Phenotypic and Molecular Networks

scientific article published on 6 April 2018

A division of medical communications in an academic medical center's department of medicine

scientific article published in December 2014

A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets

scientific article published on 06 May 2022

A genome-wide positioning systems network algorithm for in silico drug repurposing

scientific article published on 02 August 2019

A global network for network medicine

scientific article published on 31 August 2020

A randomized trial of social media from Circulation

scientific article published on 18 November 2014

A resource of lipidomics and metabolomics data from individuals with undiagnosed diseases

scientific article published on 21 April 2021

A statement on ethics from the HEART Group

scientific article

A systematic comprehensive longitudinal evaluation of dietary factors associated with acute myocardial infarction and fatal coronary heart disease

scientific article published on 27 November 2020

Adaptions to Hypoxia and Redox Stress: Essential Concepts Confounded by Misleading Terminology

scientific article published on August 2016

Adenosine-dependent induction of glutathione peroxidase 1 in human primary endothelial cells and protection against oxidative stress

scientific article published on 31 March 2005

Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism?

scientific article published in January 2003

African-American Heart Failure Trial (A-HeFT): rationale, design, and methodology

scientific article

Aldosterone Inactivates the Endothelin-B Receptor via a Cysteinyl Thiol Redox Switch to Decrease Pulmonary Endothelial Nitric Oxide Levels and Modulate Pulmonary Arterial Hypertension ⬇️

scientific article published on July 11, 2012

Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity

scientific article published on 4 February 2007

Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells

scientific article published on 13 January 2009

All That Wheezes….

scientific article published in August 2017

Alteration of relation of atherogenic lipoprotein cholesterol to apolipoprotein B by intensive statin therapy in patients with acute coronary syndrome (from the Limiting UNdertreatment of lipids in ACS With Rosuvastatin [LUNAR] Trial).

scientific article published on 10 December 2012

American Heart Association Cardiovascular Genome-Phenome Study: foundational basis and program

scientific article

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation

scientific article published in September 2009

Aminoglycosides decrease glutathione peroxidase-1 activity by interfering with selenocysteine incorporation.

scientific article published on 14 December 2005

An Unexpected Expectoration

scientific article published on 01 March 2018

An Unusual Case of Abdominal Pain

article published in 2014

An Unusual Cause of Leg Pain

scientific article published in December 2017

An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery

scientific article published on 13 August 2018

Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors

scientific article published on 01 October 2018

Analyzing networks of phenotypes in complex diseases: methodology and applications in COPD

scientific article

Antioxidant enzyme deficiencies and vascular disease

scientific article

Association studies in an era of too much information: clinical analysis of new biomarker and genetic data

scientific article published on 01 October 2007

Atherosclerotic Vascular Disease Conference: Executive summary: Atherosclerotic Vascular Disease Conference proceeding for healthcare professionals from a special writing group of the American Heart Association

scientific article

Atherosclerotic Vascular Disease Conference: Writing Group III: pathophysiology

scientific article published on June 2004

Atherothrombosis: plaque instability and thrombogenesis

scientific article

Autoimmune Cardiotoxicity of Cancer Immunotherapy

scientific article published on 2 December 2016

Back to the History

scientific article published on May 2017

Balancing role of nitric oxide in complement-mediated activation of platelets from mCd59a and mCd59b double-knockout mice

scientific article published on April 2009

Bone Morphogenetic Protein‐2 Decreases MicroRNA‐30b and MicroRNA‐30c to Promote Vascular Smooth Muscle Cell Calcification ⬇️

scientific article published on December 19, 2012

Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification.

scientific article published on 30 August 2011

Both maximal expression of selenoproteins and selenoprotein deficiency can promote development of type 2 diabetes-like phenotype in mice

scientific article

Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance

scientific article published on 24 October 2012

Building a Departmental Quality Program: A Patient-Based and Provider-Led Approach ⬇️

scientific article published on 01 March 2011

CLINICAL PROBLEM-SOLVING. A Bruising Loss

scientific article published in July 2016

CLINICAL PROBLEM-SOLVING. A Complementary Affair

scientific article published in January 2016

CLINICAL PROBLEM-SOLVING. A Man with Fever, Cough, and Rash

scientific article published on July 2015

CLINICAL PROBLEM-SOLVING. Eye of the Beholder

scientific article published in May 2016

CLINICAL PROBLEM-SOLVING. On the Nose

scientific article published on September 2015

CLINICAL PROBLEM-SOLVING. Prevention as Precipitant

scientific article published on August 2016

CLINICAL PROBLEM-SOLVING. Springing a Leak

scientific article published in October 2015

CLINICAL PROBLEM-SOLVING. Tip of the Tongue

scientific article published on September 2016

Can scientific quality be quantified?

scientific article published on 01 March 2011

Case 8-2018: A 55-Year-Old Woman with Shock and Labile Blood Pressure

scientific article published in March 2018

Case 8-2018: A Woman with Shock and Labile Blood Pressure

scientific article published on 01 May 2018

Categorizing biomedical research: the basics of translation

scientific article published on 01 August 2017

Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis

scientific article published on 28 September 2016

Cellular Redox State and Endothelial Dysfunction in Mildly Hyperhomocysteinemic Cystathionine β-Synthase–Deficient Mice ⬇️

scientific article published on January 1, 2002

Cellular glutathione peroxidase deficiency and endothelial dysfunction

scientific journal article

Circulation Cardiovascular Case Series

Clinical problem solving: Itching for a diagnosis

scientific article published on March 2015

Clinical problem-solving. A bird's-eye view of fever

scientific article published on November 2011

Clinical problem-solving. A bloody mystery

scientific article published on 01 November 2009

Clinical problem-solving. A chilly fever

scientific article published on November 2014

Clinical problem-solving. A complex cause of pleuritic chest pain

scientific article published in November 2012

Clinical problem-solving. A crazy cause of dyspnea

scientific article published on 01 January 2011

Clinical problem-solving. A curious case of chest pain.

scientific article

Clinical problem-solving. A fragile balance.

scientific article published in July 2009

Clinical problem-solving. A heavy heart

scientific article published on 01 October 2010

Clinical problem-solving. A patient with migrating polyarthralgias

scientific article published on July 2013

Clinical problem-solving. A patient with syncope

scientific article published in September 2013

Clinical problem-solving. A rash hypothesis

scientific article published in July 2010

Clinical problem-solving. A sleeping giant

scientific article published on 01 July 2011

Clinical problem-solving. A startling decline

scientific article published in March 2012

Clinical problem-solving. A sweet source of abdominal pain

scientific article published on 01 May 2011

Clinical problem-solving. A tight predicament

scientific article published in September 2014

Clinical problem-solving. Against the grain

scientific article published on 01 October 2014

Clinical problem-solving. At a loss

scientific article published in July 2012

Clinical problem-solving. Bitter pills

scientific article published on November 2010

Clinical problem-solving. Breathless

scientific article

Clinical problem-solving. Breathtaking journey

scientific article published on August 2012

Clinical problem-solving. Hard to conceive

scientific article published on September 2010

Clinical problem-solving. In the thick of it.

scientific article published in May 2013

Clinical problem-solving. Lying low

scientific article published on 01 March 2011

Clinical problem-solving. Out of the blue

scientific article published in May 2014

Clinical problem-solving. Painful purple toes

scientific article published in January 2010

Clinical problem-solving. Stalking the diagnosis

scientific article published in March 2010

Clinical problem-solving. The beat goes on.

scientific article published in May 2010

Clinical problem-solving. The search is on.

scientific article published in February 2013

Clinical problem-solving. The writing on the wall

scientific article published in October 2009

Clinical problem-solving. Waiting for the other foot to drop

scientific article published on June 2013

Clinical problem-solving. Wasting away

scientific article published on 01 March 2014

Clinical problem-solving. Whistling in the dark

scientific article published on 01 May 2012

Clinical trials in cardiovascular medicine in an era of marginal benefit, bias, and hyperbole

scientific article

Comparison of Protein N-Homocysteinylation in Rat Plasma under Elevated Homocysteine Using a Specific Chemical Labeling Method

scientific article published on 08 September 2016

Comparison of lipid-modifying efficacy of rosuvastatin versus atorvastatin in patients with acute coronary syndrome (from the LUNAR study).

scientific article published on 21 February 2012

Complements from the Lung

scientific article published on 01 November 2018

Complexity and network dynamics in physiological adaptation: an integrated view

scientific article published on 18 April 2014

Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors

scholarly article

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes

scientific article published on 29 November 2017

Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.

scientific article

Coronary calcium screening and the American Heart Association news embargo

scientific article

Creating Real Change at Academic Medical Centers - How Social Movements Can Be Timely Catalysts

scientific article published on 10 June 2020

Cyclooxygenase inhibition and cardiovascular risk

scientific article

Deciphering the molecular basis of human cardiovascular disease through network biology ⬇️

scientific article published on May 1, 2012

Determinants of drug-target interactions at the single cell level

Determinants of human plasma glutathione peroxidase (GPx-3) expression

scientific article published on 19 April 2004

Different effects of angiotensin receptor blockade on end-organ damage in salt-dependent and salt-independent hypertension

scientific article published on 21 August 2006

Discovering the full spectrum of cardiovascular disease: Minority Health Summit 2003: report of the Basic Science Writing Group

scientific article published on 01 March 2005

Disease networks. Uncovering disease-disease relationships through the incomplete interactome

scientific article published on February 2015

DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections

scientific article

Drug-Placebo Additivity in Randomized Clinical Trials

scientific article published on 26 October 2019

Drugst.One — a plug-and-play solution for online systems medicine and network-based drug repurposing

scientific article published in 2024

Dyspnea and Edema in a Woman With Antiphospholipid Syndrome

scientific article published on 01 November 2018

Early pregnancy vitamin D status and risk of preeclampsia

scientific article

Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta

scientific article published on 12 October 2020

Editor's note

scientific article published in April 2013

Effect of 5-lipoxygenase on the development of pulmonary hypertension in rats

scientific article

Effect of FXIII on monocyte and fibroblast function

scientific article published on 01 January 2007

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease

Effectiveness of Spironolactone Plus Ambrisentan for Treatment of Pulmonary Arterial Hypertension (from the [ARIES] Study 1 and 2 Trials) ⬇️

scientific article published on 07 June 2013

Effects of black race on forearm resistance vessel function

scientific article published in August 2002

Efficient Computational Modeling of Human Ventricular Activation and Its Electrocardiographic Representation: A Sensitivity Study.

scientific article published on 16 March 2018

Elevated levels of homocysteine compromise blood-brain barrier integrity in mice

scientific article published on 27 September 2005

Elevated pulmonary arterial and systemic plasma aldosterone levels associate with impaired cardiac reserve capacity during exercise in left ventricular systolic heart failure patients: A pilot study

scientific article published on 19 October 2015

Emerging Role of Precision Medicine in Cardiovascular Disease

scientific article

Endogenous mechanisms of inhibition of platelet function

scientific article

Endophenotype Network Models: Common Core of Complex Diseases

scientific article published on 09 June 2016

Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia

scientific article

Entrepreneurship in the medical academy: possibilities and challenges in commercialization of research discoveries

scientific article published in March 2007

Epigenetic Inheritance Underlying Pulmonary Arterial Hypertension

scientific article published on 01 April 2019

Epigenetic modifications: basic mechanisms and role in cardiovascular disease (2013 Grover Conference series).

scientific article

Epigenetic modifications: basic mechanisms and role in cardiovascular disease.

scientific article

Ethics and professionalism: can there be consensus? An editorial comment on the report of the ACCF/AHA Consensus Conference on Professionalism and Ethics

scientific article published in October 2004

Evaluation of a redesign initiative in an internal-medicine residency

scientific article published in April 2010

Evaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice

scientific article published on 01 March 2006

Ever at the mercy of well-intentioned regulations: their adverse consequences and unproven benefits

scientific article published in March 2013

Evidence for human lung stem cells

scientific article

Expert Panel Discusses the Importance of Systems Medicine

scholarly article published in June 2018

Expression of 5-lipoxygenase in pulmonary artery endothelial cells

scientific article

Expression of concern

scientific article published on 01 February 2015

Extensive cerebral venous thrombosis associated with moderate hyperhomocyst(e)inemia and successfully treated with thrombolysis

scientific article published on 01 January 2002

Facing Uncertainty

scientific article published on 01 December 2019

Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity

scientific article published on 15 August 2019

From Clinical Observation to Mechanism — Heyde's Syndrome ⬇️

scientific article published on November 15, 2012

From clinical observation to mechanism--Heyde's syndrome

scientific article published on 01 February 2013

Frontiers in nephrology: targeting inflammation using novel nitric oxide donors

scientific article published on 17 October 2007

Functional polymorphisms in a candidate gene for atherothrombosis: unraveling the complex fabric of a polygenic phenotype

scientific article published on 01 March 2003

Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association

scientific article

GAPDH inhibits intracellular pathways during starvation for cellular energy homeostasis

scientific article published in Nature

Gasping for a Diagnosis

scientific article published on 01 March 2019

Genetic Misdiagnoses and the Potential for Health Disparities

scientific article

Genetic determinants of arterial thrombosis

scientific article published on 13 November 2003

Genetic determinants of vascular oxidant stress and endothelial dysfunction

scientific article

Genetically encoded fluorescent sensors for intracellular NADH detection

scientific article published on October 2011

Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

scientific article published on 05 June 2017

Genetics and beyond--the transcriptome of human monocytes and disease susceptibility

scientific article (publication date: 18 May 2010)

Genetics and the placebo effect: the placebome

scientific article published on 14 April 2015

Genetics of thrombophilia: impact on atherogenesis

scientific article published on April 2004

Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II

scientific journal article

Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice

scientific article

Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes

scientific article

Glucose-6-phosphate dehydrogenase modulates vascular endothelial growth factor-mediated angiogenesis

scientific article

Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide

scientific article

Glucose-6-phosphate dehydrogenase-deficient mice have increased renal oxidative stress and increased albuminuria

scientific article

Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities ⬇️

scientific article published on April 10, 2011

Glutathione Peroxidase-3 Deficiency Promotes Platelet-Dependent Thrombosis In Vivo ⬇️

scientific article published on April 25, 2011

Glutathione peroxidase deficiency exacerbates ischemia-reperfusion injury in male but not female myocardium: insights into antioxidant compensatory mechanisms

scientific article published on 02 October 2009

Glutathione peroxidase-1 deficiency augments proinflammatory cytokine-induced redox signaling and human endothelial cell activation.

scientific article

Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression

scientific article

Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses

scientific article

Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells

scientific article

Gut Microbiota, the Genome, and Diet in Atherogenesis ⬇️

scientific article published on April 25, 2013

Hepatocellular carcinoma with intracavitary cardiac involvement: a case report and review of the literature

scientific article published on 10 July 2008

Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure

scientific journal article

High glucose inhibits glucose-6-phosphate dehydrogenase, leading to increased oxidative stress and beta-cell apoptosis

scientific article

High-resolution imaging of selenium in kidneys: a localized selenium pool associated with glutathione peroxidase 3.

scientific article published on 22 November 2011

Hippocrates' First Aphorism: Reflections on Ageless Principles for the Practice of Medicine

scientific article published in January 2016

Holding Our Breath: The Emerging and Anticipated Roles of microRNA in Pulmonary Hypertension ⬇️

scientific article published on July 1, 2012

Homocysteine

scientific article published on 01 September 2006

Homocysteine and atherothrombosis: diagnosis and treatment

scientific article

Homocysteine and cardiovascular risk: the perils of reductionism in a complex system

scientific article published on 23 May 2012

Homocysteine and dementias

scientific article published in February 2002

Homocysteine and glutathione peroxidase-1.

scientific article

Homocysteine down-regulates cellular glutathione peroxidase (GPx1) by decreasing translation

scientific article published on 25 February 2005

Homocysteine impairs coronary microvascular dilator function in humans

scientific article published in September 2002

Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress ⬇️

scientific article published on December 29, 2011

Homocysteine trials--clear outcomes for complex reasons

scientific article published on 12 March 2006

Homocysteine-mediated thrombosis and angiostasis in vascular pathobiology

scientific article published on 19 October 2009

Human alpha B-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice

scientific article

Human disease classification in the postgenomic era: a complex systems approach to human pathobiology

scientific article

Hyperhomocysteinemia from trimethylation of hepatic phosphatidylethanolamine during cholesterol cholelithogenesis in inbred mice

scientific article

Hypoxamirs and mitochondrial metabolism

scientific article

Hypoxia potentiates nitric oxide-mediated apoptosis in endothelial cells via peroxynitrite-induced activation of mitochondria-dependent and -independent pathways

scientific article published on 3 November 2003

Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress

scientific article published on 23 July 2015

Hypoxia-induced suppression of c-Myc by HIF-2α in human pulmonary endothelial cells attenuates TFAM expression

scientific article published on 12 July 2017

Hypoxia: a master regulator of microRNA biogenesis and activity

scientific article published on 24 May 2013

IRF2BPL Is Associated with Neurological Phenotypes

Identification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center

scientific article published on 29 October 2019

Identification of cholesteryl esters in human carotid atherosclerosis by ex vivo image-guided proton MRS.

scientific article

Identification of druggable host targets needed for SARS-CoV-2 infection by combined pharmacological evaluation and cellular network directed prioritization both in vitro and in vivo

scientific article published on 20 April 2021

Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization

scientific article published on 16 September 2022

Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor

scientific article published on 10 March 2020

Illuminating drug action by network integration of disease genes: a case study of myocardial infarction

scientific article published on 23 March 2016

Impaired angiogenesis in glutathione peroxidase-1-deficient mice is associated with endothelial progenitor cell dysfunction

scientific journal article

Importance of scientific collaboration in contemporary drug discovery and development: a detailed network analysis

scientific article published on 13 October 2020

In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD(+)/NADH redox state

scientific article published on 30 June 2016

Incorporation of heparin-binding proteins into preformed dextran sulfate-chitosan nanoparticles

scientific article published on 18 November 2016

Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase

scientific journal article

Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice ⬇️

scientific article published in 2005

Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose

scientific article

Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes

scientific article published on 08 February 2021

Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice

scientific journal article

Influence of hyperhomocysteinemia on the cellular redox state--impact on homocysteine-induced endothelial dysfunction

scientific article published on November 2003

Inhibition of cellular methyltransferases promotes endothelial cell activation by suppressing glutathione peroxidase 1 protein expression

scientific article

Interactive Medical Cases — A NewJournalFeature

Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association

scientific article published on 01 June 2018

Internal medicine residency redesign: proposal of the Internal Medicine Working Group

scientific article published on September 2011

International Exchange and American Medicine

scientific article published in February 2017

Is Oxygen Therapy Beneficial in Acute Myocardial Infarction? Simple Question, Complicated Mechanism, Simple Answer

scientific article published on 28 August 2017

James. T. Willerson, MD; In Memoriam

scientific article published on 23 September 2020

Joseph A. Vita, MD, 1956-2014.

scientific article published in January 2015

Joseph A. Vita, MD, 1956-2014.

scientific article published on 26 January 2015

Joseph Loscalzo, MD, PhD: a conversation with the Editor. Interview by William Clifford Roberts

scientific article published on 13 February 2006

Just a Cut.

scientific article

Keshan disease, selenium deficiency, and the selenoproteome

scientific article published on May 2014

L-Homocysteine and L-homocystine stereospecifically induce endothelial nitric oxide synthase-dependent lipid peroxidation in endothelial cells

scientific article published in March 2004

L-arginine and atherothrombosis

scientific article

Lipid Metabolism by Gut Microbes and Atherosclerosis ⬇️

scientific article published on 01 July 2011

Lipid levels after acute coronary syndromes

scientific article published on April 2008

MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells

scientific article published on 12 May 2020

Maintenance of certification: Good intentions gone awry

scientific article published on 18 December 2014

Making the Connection

scientific article published on 01 February 2017

Mechanism of disease: Pulmonary hypertension

scientific article published on 01 February 2005

Membrane redox state and apoptosis: death by peroxide

scientific article published on September 2008

Metabolic Responses to Reductive Stress

scientific article published on 18 July 2019

Methoxistasis: integrating the roles of homocysteine and folic acid in cardiovascular pathobiology

scientific article published on 15 August 2013

MicroRNA Dysregulation in Pulmonary Arteries from Chronic Obstructive Pulmonary Disease. Relationships with Vascular Remodeling

scientific article published on 01 October 2018

MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach

scientific article published on 27 February 2012

MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2

scientific article

MicroRNA-210: a unique and pleiotropic hypoxamir

scientific article

Missing the Target

scientific article published on 01 April 2020

Molecular mechanisms underlying the proangiogenic effect of factor XIII.

scientific article published on 23 December 2004

Molecular networks in Network Medicine: Development and applications

scientific article published on 19 April 2020

Moving Beyond the Sarcomere to Explain Heterogeneity in Hypertrophic Cardiomyopathy: JACC Review Topic of the Week

scientific article published on 01 April 2019

Myocardial hibernation: restorative or preterminal sleep?

scientific article published in April 2002

NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism

scientific article

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension

scientific article published on 01 June 2018

NIH Centers for Accelerated Innovations Program: principles, practices, successes and challenges

scientific article

Nanoglycan complex formulation extends VEGF retention time in the lung

scientific article published on July 2010

NetMedPy: A Python package for Large-Scale Network Medicine Screening

scientific article published on 8 September 2024

Network Analysis to Risk Stratify Patients with Exercise Intolerance

scientific article published on 5 February 2018

Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19

scientific article published on 15 April 2020

Network Medicine In Cardiovascular Research

scientific article published on 09 November 2020

Network Medicine in Pathobiology

scientific article published on 20 April 2019

Network analysis of the genomic basis of the placebo effect

scientific article

Network determinants of cardiovascular calcification and repositioned drug treatments

scientific article published on 08 July 2020

Network medicine and type 2 diabetes mellitus: insights into disease mechanism and guide to precision medicine

scientific article published on 13 August 2019

Network medicine framework for identifying drug-repurposing opportunities for COVID-19

scientific article published on 11 May 2021

Network medicine framework shows that proximity of polyphenol targets and disease proteins predicts therapeutic effects of polyphenols

scientific article published in 2021

Network-Based Disease Module Discovery by a Novel Seed Connector Algorithm with Pathobiological Implications

scientific article published on 20 May 2018

Network-based approach to prediction and population-based validation of in silico drug repurposing.

scientific article published on 12 July 2018

Network-based association of hypoxia-responsive genes with cardiovascular diseases

scientific article published on October 2014

New Challenges for ACE-Inhibitors in Vascular Diseases

New section in Circulation: implications of contemporary clinical trials

scientific article published on 01 June 2010

Nitric Oxide Signaling and Atherothrombosis Redux: Evidence From Experiments of Nature and Implications for Therapy

scientific article published in January 2018

Nitric oxide and other novel therapies for pulmonary hypertension

scientific article published on March 2004

Nitric oxide and posttranslational modification of the vascular proteome: S-nitrosation of reactive thiols

scientific article published on 16 March 2006

Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview

scientific article

Nitric oxide insufficiency and atherothrombosis

scientific article published on 26 August 2004

Nitric oxide's role in heart failure: pathophysiology and treatment. Introduction

scientific article published in October 2003

Nitroglycerin and Nitric Oxide--A Rondo of Themes in Cardiovascular Therapeutics

scientific article published on July 2015

Nitroglycerin and Nitric Oxide--A Rondo of Themes in Cardiovascular Therapeutics

scientific article published on 01 October 2015

Nitroso-oxidative stress and cardiovascular disease

scholarly article

Novel proangiogenic effect of factor XIII associated with suppression of thrombospondin 1 expression

scientific article published on 12 June 2003

Nutri(meta)genetics and cardiovascular disease: novel concepts in the interaction of diet and genomic variation

scientific article

One is the loneliest number: genotypic matchmaking using the electronic health record

scientific article published on 06 July 2021

Opportunities for the Cardiovascular Community in the Precision Medicine Initiative

scientific article

Oxidative enzymopathies and vascular disease

scientific article

Oxidative mechanisms and atherothrombotic cardiovascular disease

scientific article published on March 2008

Oxidative risk for atherothrombotic cardiovascular disease

scientific article

Oxidative stress in endothelial cell dysfunction and thrombosis

scientific article published in September 2002

Ozone--from environmental pollutant to atherogenic determinant

scientific article published in February 2004

Paraoxonase 192 Gln-->Arg polymorphism: an independent risk factor for nonfatal arterial ischemic stroke among young adults

scientific article

Paraoxonase and coronary heart disease risk: language misleads, linkage misinforms, function clarifies

scientific article published on 01 December 2008

Parroting Lymphoma

scientific article published on 01 October 2020

Pathogenic mechanisms of pulmonary arterial hypertension

scientific article published on 20 September 2007

Personalized cardiovascular medicine and drug development: time for a new paradigm

scientific article published on January 2012

Pharmacogenomics and the Placebo Response.

scientific article published on 2 March 2018

Physiological stress increases renal injury in eNOS-knockout mice ⬇️

scientific article published on December 15, 2011

Pilot trials in clinical research: of what value are they?

scientific article published on 01 April 2009

Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study

scientific article published on 30 October 2012

Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events

scientific article

Platelet-monocyte aggregates: bridging thrombosis and inflammation

scientific article published on 01 May 2002

Platelets and cardiovascular disease

scientific article published on December 1, 2002

Polymorphisms in catechol-O-methyltransferase modify treatment effects of aspirin on risk of cardiovascular disease

scientific article

Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function

scientific article published on 13 December 2017

Precision Medicine ⬇️

scientific article published in March 2019

Precision Psychiatry Meets Network Medicine: Network Psychiatry.

scientific article published in July 2017

Precision medicine in cardiology

scientific article

Predictors of improved left ventricular systolic function in an urban cardiomyopathy program

scientific article (publication date: 15 December 2006)

Preface

Preparation and characterization of SDF-1α-chitosan-dextran sulfate nanoparticles

scientific article published on 22 January 2015

Prevention of hypertension and renal dysfunction in Dahl rats by alpha-tocopherol

scientific article

Primer on medical genomics. Part XIV: Introduction to systems biology--a new approach to understanding disease and treatment

scientific article published on May 2004

Promoter polymorphisms in the plasma glutathione peroxidase (GPx-3) gene: a novel risk factor for arterial ischemic stroke among young adults and children.

scientific article published on 22 November 2006

Protective effects of dietary potassium chloride on hemodynamics of Dahl salt-sensitive rats in response to chronic administration of sodium chloride

scientific article

Proteomics in cardiovascular biology and medicine

scientific article

Prothrombotic determinants of coronary atherothrombosis ⬇️

scientific article published on January 1, 2002

Publisher Correction: The unmapped chemical complexity of our diet ⬇️

scholarly article

Pulmonary Arterial Hypertension

scientific article published on 01 October 2004

Pulmonary Comorbidity in Lung Cancer

scientific article published in February 2018

Pulmonary Vascular Disease Related to Hemodynamic Stress in the Pulmonary Circulation ⬇️

scientific article published on January 1, 2011

Pulmonary arterial hypertension

Pulmonary hypertension: pathophysiology and signaling pathways

scientific article published on January 2013

Putting the Patient Back Together - Social Medicine, Network Medicine, and the Limits of Reductionism

scientific article published in December 2017

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