List of works - Jonathan V Rocheleau

A microfluidic device designed to induce media flow throughout pancreatic islets while limiting shear-induced damage.

scientific article published in November 2013

Allosteric modulation in monomers and oligomers of a G protein-coupled receptor

scientific article published on 06 May 2016

Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+).

scientific article published on 15 February 2016

Autofluorescence imaging of living pancreatic islets reveals fibroblast growth factor-21 (FGF21)-induced metabolism.

scientific article published on December 2012

Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis

scientific article published on 12 December 2016

Culturing Pancreatic Islets in Microfluidic Flow Enhances Morphology of the Associated Endothelial Cells ⬇️

scientific article published on September 22, 2011

Dynamics and Distribution of Klothoβ (KLB) and Fibroblast Growth Factor Receptor-1 (FGFR1) in Living Cells Reveal the Fibroblast Growth Factor-21 (FGF21)-induced Receptor Complex ⬇️

scientific article published on April 20, 2012

Dynamin-Related Protein 1-Dependent Mitochondrial Fission Changes in the Dorsal Vagal Complex Regulate Insulin Action ⬇️

scientific article

Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation

scientific article published on 14 September 2018

GABA promotes β-cell proliferation, but does not overcome impaired glucose homeostasis associated with diet-induced obesity

scientific article published on 03 December 2018

Highly efficient adenoviral transduction of pancreatic islets using a microfluidic device.

scientific article published on 5 July 2016

Hypoxia induction in cultured pancreatic islets enhances endothelial cell morphology and survival while maintaining beta-cell function

scientific article published on 10 October 2019

Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin

scientific article published on 16 July 2015

Inside-out signaling promotes dynamic changes in the carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) oligomeric state to control its cell adhesion properties.

scientific article published on 04 September 2013

Isolation of Phenotypically Distinct Cancer Cells Using Nanoparticle-Mediated Sorting.

scientific article published on 26 May 2017

Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis

scientific journal article

LKB1 couples glucose metabolism to insulin secretion in mice.

scientific article published on 16 April 2015

Leveraging multimodal microscopy to optimize deep learning models for cell segmentation

scientific article published on 04 January 2021

OASIS/CREB3L1 Induces Expression of Genes Involved in Extracellular Matrix Production But Not Classical Endoplasmic Reticulum Stress Response Genes in Pancreatic β-Cells ⬇️

scientific article published on July 28, 2010

Quantitative imaging of electron transfer flavoprotein autofluorescence reveals the dynamics of lipid partitioning in living pancreatic islets ⬇️

scientific article published on June 25, 2012

Rapid Extravasation and Establishment of Breast Cancer Micrometastases in the Liver Microenvironment ⬇️

scientific article published on August 19, 2010

Single-Molecule Analysis of the Supramolecular Organization of the M2 Muscarinic Receptor and the Gαi1 Protein.