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List of works by Clifton Bogardus

11beta-Hydroxysteroid dehydrogenase Type 1: genetic polymorphisms are associated with Type 2 diabetes in Pima Indians independently of obesity and expression in adipocyte and muscle

scientific article

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A C-reactive protein promoter polymorphism is associated with type 2 diabetes mellitus in Pima Indians

scientific article

A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians

scientific article published on 5 May 2017

A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians

scientific article published in March 2003

A Human Thrifty Phenotype Associated With Less Weight Loss During Caloric Restriction

scientific article published on 11 May 2015

A Low Sympathoadrenal Activity is Associated with Body Weight Gain and Development of Central Adiposity in Pima Indian Men ⬇️

scientific article published on July 1, 1997

A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array

scientific article published on 10 September 2007

A Ser311Cys mutation in the human dopamine receptor D2 gene is associated with reduced energy expenditure

scientific article published in April 2001

A brief overview of human energy metabolism and its relationship to essential obesity

scientific article published on January 1992

A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance

scientific article

A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians

scientific article published on 6 February 2015

A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes ⬇️

scientific article published on September 1, 1998

A functional Tyr1306Cys variant in LARG is associated with increased insulin action in vivo

scientific article published on May 2006

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians

scientific article published on July 2003

A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes

scientific journal article

A genome-wide association study of BMI in American Indians

scientific article published on 23 June 2011

A high concentration of fasting plasma non-esterified fatty acids is a risk factor for the development of NIDDM.

scientific article published in October 1995

A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance: evidence for a pathogenic role of relative hyperinsulinemia.

scientific article

A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians

scientific article

A polymorphism in the human intestinal fatty acid binding protein alters fatty acid transport across Caco-2 cells

scientific article published on 01 May 1996

A type 2 diabetes-associated polymorphic ARE motif affecting expression of PPP1R3 is involved in RNA-protein interactions

scientific article

ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

scientific article

Abnormal Regulation of Protein Tyrosine Phosphatase Activities in Skeletal Muscle of Insulin-Resistant Humans ⬇️

scientific article published on July 1, 1991

Absence of linkage of obesity and energy metabolism to markers flanking homologues of rodent obesity genes in Pima Indians

scientific article

Absence of mutations in the human OB gene in obese/diabetic subjects

scientific article published on May 1996

Acute insulin response is an independent predictor of type 2 diabetes mellitus in individuals with both normal fasting and 2-h plasma glucose concentrations

scientific article

Adenosine 3',5'-monophosphate-dependent protein kinase activity decreases in human muscle after insulin infusion

scientific article published on 01 October 1989

An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance

scientific article

An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians

scientific article published on April 1998

Analysis of Linkage Disequilibrium between Polymorphisms in the KCNJ9 Gene with Type 2 Diabetes Mellitus in Pima Indians

article

Analysis of MGEA5 on 10q24.1-q24.3 encoding the beta-O-linked N-acetylglucosaminidase as a candidate gene for type 2 diabetes mellitus in Pima Indians

scientific article

Analysis of PBX1 as a candidate gene for type 2 diabetes mellitus in Pima Indians

scientific article

Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression

scientific article published on 20 October 2015

Analysis of slc19a2, on 1q23.3 encoding a thiamine transporter as a candidate gene for type 2 diabetes mellitus in pima indians

scientific article published in April 2001

Analysis of the SIM1 contribution to polygenic obesity in the French population

scientific article

Analysis of the lamin A/C gene as a candidate for type II diabetes susceptibility in Pima Indians

scientific article published in June 2001

Antecedent events for non-insulin dependent diabetes mellitus

scientific article published on January 1988

Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians

scientific article

Assessing accuracy of genotype imputation in American Indians

scientific article

Assessing established BMI variants for a role in nighttime eating behavior in robustly phenotyped Southwestern American Indians

scientific article published on 12 May 2020

Assessing the Role of 98 Established Loci for BMI in American Indians

scientific article published on 18 March 2019

Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3.

scientific article published on 8 November 2016

Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians

scientific article published on 15 December 2015

Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians

scientific article published on 5 December 2011

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians

scientific article published on July 2008

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians

scientific article

Association of a F479L variant in the cytosolic phospholipase A2 gene (PLA2G4A) with decreased glucose turnover and oxidation rates in Pima Indians

scientific article published on May 2003

Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians

scientific article published in March 2006

Association of dopamine D2 receptor polymorphisms Ser311Cys and TaqIA with obesity or type 2 diabetes mellitus in Pima Indians

scientific article published on 01 October 2000

Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians

scientific article

Autoantibodies against PFDN2 are associated with an increased risk of type 2 diabetes: A case-control study.

scientific article

Autosomal genomic scan for loci linked to obesity and energy metabolism in Pima Indians

scientific article

Bimodal distribution of RNA expression levels in human skeletal muscle tissue

scientific article

Body weight gain in free-living Pima Indians: effect of energy intake vs expenditure

scientific article published on 01 December 2003

CHRM3 gene variation is associated with decreased acute insulin secretion and increased risk for early-onset type 2 diabetes in Pima Indians.

scientific article

Changing habits to delay diabetes

scientific article

Characterization of Exome Variants and Their Metabolic Impact in 6,716 American Indians from the Southwest US

scientific article published on 02 July 2020

Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretion

scientific article published in July 2001

Cloning, expression and genomic structure of human LMX1A, and variant screening in Pima Indians

scientific article

Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children

scientific article

Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure

scientific article

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians

scientific article published on 28 April 2009

Comparison of carbohydrate-containing and carbohydrate-restricted hypocaloric diets in the treatment of obesity. Endurance and metabolic fuel homeostasis during strenuous exercise ⬇️

scientific article published on August 1, 1981

Comparison of carbohydrate-containing and carbohydrate-restricted hypocaloric diets in the treatment of obesity: effects of appetite and mood

scientific article published in September 1982

Concomitant interindividual variation in body temperature and metabolic rate

scientific article published on October 1, 1992

Correlation between muscle glycogen synthase activity and in vivo insulin action in man.

scientific article

Currently identified genes affecting insulin resistance are not associated with birth weight in the Pima population

scientific article published in October 2002

Decline in the acute insulin response in relationship to plasma glucose concentrations

scientific article published on 25 September 2017

Defective insulin response of cyclic adenosine monophosphate-dependent protein kinase in insulin-resistant humans

scientific article

Defective insulin response of phosphorylase phosphatase in insulin-resistant humans ⬇️

scientific article published on February 1, 1992

Deficiency in phosphorylase phosphatase activity despite elevated protein phosphatase type-1 catalytic subunit in skeletal muscle from insulin-resistant subjects

scientific article

Deterioration in carbohydrate metabolism and lipoprotein changes induced by modern, high fat diet in Pima Indians and Caucasians

scientific article published on 01 July 1991

Determinants of 24-hour energy expenditure in man. Methods and results using a respiratory chamber

scientific article

Determinants of energy expenditure and fuel utilization in man: effects of body composition, age, sex, ethnicity and glucose tolerance in 916 subjects

scientific article published on 01 July 1999

Differences in oral temperature and body shape in two populations with different propensities for obesity.

scientific article published in June 2002

Differential expression of matrix metalloproteinase 3 (MMP3) in preadipocytes/stromal vascular cells from nonobese nondiabetic versus obese nondiabetic Pima Indians.

scientific article

Differential methylation of genes in individuals exposed to maternal diabetes in utero

scientific article published on 26 January 2017

Distribution of in vivo insulin action in Pima Indians as mixture of three normal distributions

scientific article

Effect of elevated FFA on carbohydrate and lipid oxidation during prolonged exercise in humans

scientific article published on 01 March 1986

Effect of muscle glycogen depletion on in vivo insulin action in man.

scientific article published on November 1983

Effect of paternal diabetes on pre-diabetic phenotypes in adult offspring ⬇️

scientific article

Effects of Physical Training and Diet Therapy on Carbohydrate Metabolism in Patients with Glucose Intolerance and Non-insulin-dependent Diabetes Mellitus ⬇️

scientific article published on April 1, 1984

Effects of acute hyperinsulinemia on plasma leptin concentrations in insulin-sensitive and insulin-resistant Pima Indians

scientific article published in December 1996

Effects of an Ala54Thr polymorphism in the intestinal fatty acid-binding protein on responses to dietary fat in humans.

scientific article published in December 2000

Effects of carbohydrate-containing and carbohydrate-restricted hypocaloric and eucaloric diets on serum concentrations of retinol-binding protein, thyroxine-binding prealbumin and transferrin

scientific article published on 01 January 1983

Elevated plasma nonesterified fatty acids are associated with deterioration of acute insulin response in IGT but not NGT.

scientific article

Endogenous glucose production, insulin sensitivity, and insulin secretion in normal glucose-tolerant Pima Indians with low birth weight

scientific article

Energy expenditure by doubly labeled water: validation in lean and obese subjects

scientific article published in September 1991

Energy expenditure during normo- and overfeeding in peripubertal children of lean and obese Pima Indians

scientific article

Energy expenditure in the obese: is there a thrifty gene?

scientific article published on April 1990

Energy expenditure, fat oxidation, and body weight regulation: a study of metabolic adaptation to long-term weight change

scientific article

Energy metabolism in African Americans: potential risk factors for obesity

scientific article published in July 1999

Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans

scientific article

Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance

scientific article

Erratum to “A C-reactive protein promoter polymorphism is associated with type 2 diabetes mellitus in Pima Indians” [Mol. Genet. Metab. 78 (2003) 136–144]

scholarly article published in Molecular Genetics and Metabolism

Ethnic differences in sympathetic nervous system-mediated energy expenditure ⬇️

scientific article published on December 1, 1991

Euglycemic hyperinsulinemia increases glucose 1,6-bisphosphate in human skeletal muscle

scientific article published on 01 January 1989

Evaluation of A2BP1 as an obesity gene ⬇️

scientific article

Evaluation of simple indices of insulin sensitivity and insulin secretion for use in epidemiologic studies

scientific article

Evaluation of the microsomal glutathione S-transferase 3 (MGST3) locus on 1q23 as a Type 2 diabetes susceptibility gene in Pima Indians

scientific article

Evidence for Linkage Between a Region on Chromosome 1p and the Acute Insulin Response in Pima Indians ⬇️

scientific article published on April 1, 1995

Evidence for a Role of LPGAT1 in Influencing BMI and Percent Body Fat in Native Americans

scholarly article by Michael T. Traurig et al published 22 June 2012 in Obesity

Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans

scientific article published on January 2013

Evidence for reduced thermic effect of insulin and glucose infusions in Pima Indians

scientific article

Exaggerated early insulin release and insulin resistance in a diabetes-prone population: a metabolic comparison of Pima Indians and Caucasians

scientific article published in October 1991

Exaggerated insulin secretion in Pima Indians and African-Americans but higher insulin resistance in Pima Indians compared to African-Americans and Caucasians

scientific article published in October 2004

Exaggerated pancreatic polypeptide secretion in Pima Indians: can an increased parasympathetic drive to the pancreas contribute to hyperinsulinemia, obesity, and diabetes in humans?

scientific article published in February 2001

Exome sequencing identifies a nonsense variant in DAO associated with reduced energy expenditure in American Indians

scientific article published on 20 August 2020

FGF21 is a Hormonal Mediator of the Human "Thrifty" Metabolic Phenotype

scientific article published on 26 September 2018

Familial dependence of the resting metabolic rate

scientific article published on 01 July 1986

Familiality of physical and metabolic characteristics that predict the development of non-insulin-dependent diabetes mellitus in Pima Indians.

scientific article

Fasting hyperglycemia predicts lower rates of weight gain by increased energy expenditure and fat oxidation rate

scientific article

Free fatty acid metabolism and obesity in man: in vivo in vitro comparisons

scientific article published on 01 June 1986

Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex

scientific article published on 4 January 2018

Functional variants in MBL2 are associated with type 2 diabetes and pre-diabetes traits in Pima Indians and the old order Amish

scientific article

Genetic variation in UCP2 (uncoupling protein-2) is associated with energy metabolism in Pima Indians

scientific article published on 16 September 2005

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

scientific journal article

Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians

scientific article

Genome-wide scan for CAG/CTG repeat expansions in Pimas with early onset of type 2 diabetes mellitus

scientific article published on 01 January 1999

Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group

scientific article

Glucose allostasis

scientific article published in April 2003

Glucose allostasis: disrobing common wisdom

scientific article published on 6 March 2009

Glucose storage is a major determinant of in vivo "insulin resistance" in subjects with normal glucose tolerance

scientific article published on 01 May 1986

Glucose-6-phosphate stimulation of human muscle glycogen synthase phosphatase

scientific article published on 01 December 1988

Glucose-induced thermogenesis and insulin resistance in man

scientific article published on 01 January 1985

Glycemic response to stress is altered in euglycemic Pima Indians

scientific article published on 01 November 1994

Glycogen synthase: a putative locus for diet-induced hyperglycemia.

scientific article

Greater impact of melanocortin-4 receptor deficiency on rates of growth and risk of type 2 diabetes during childhood compared with adulthood in Pima Indians

scientific article published on 21 November 2011

HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion

scientific article

High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes

scientific article published in June 2002

High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes

scientific article published on February 2002

Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans

scientific article published in September 2006

Hyperglycemia stimulates carbohydrate oxidation in humans

scientific article published on 01 October 1987

Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians

scientific article published on 22 February 2018

Identification of differentially expressed genes in skeletal muscle of non-diabetic insulin-resistant and insulin-sensitive Pima Indians by differential display PCR ⬇️

scientific article published on October 24, 2003

Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes

scientific article published on 7 March 2013

Identification of individuals with insulin resistance using routine clinical measurements

scientific article

Identification of novel putative membrane proteins selectively expressed during adipose conversion of 3T3-L1 cells

scientific article published on May 2002

Identification of susceptibility genes for complex metabolic diseases.

scientific article

Impaired Metabolic Flexibility to High-Fat Overfeeding Predicts Future Weight Gain in Healthy Adults

scientific article published on 11 November 2019

Impaired glucose tolerance as a disorder of insulin action. Longitudinal and cross-sectional studies in Pima Indians

scientific article

Impaired insulin-stimulated muscle glycogen synthase activation in vivo in man is related to low fasting glycogen synthase phosphatase activity

scientific article published on November 1988

In vitro insensitivity of glucose transport and antilipolysis to insulin due to receptor and postreceptor abnormalities in obese Pima Indians with normal glucose tolerance

scientific article published on 01 August 1984

In vivo insulin action is familial characteristic in nondiabetic Pima Indians

scientific article published in November 1987

Increased Rate of Cori Cycle in Obese Subjects With NIDDM and Effect of Weight Reduction ⬇️

scientific article published on February 1, 1988

Increased expression of inflammation-related genes in cultured preadipocytes/stromal vascular cells from obese compared with non-obese Pima Indians

scientific article

Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals

scientific article published in February 2008

Increased resting metabolic rates in obese subjects with non-insulin-dependent diabetes mellitus and the effect of sulfonylurea therapy

scientific article published on 01 January 1986

Insulin action in obese non-insulin-dependent diabetics and in their isolated adipocytes before and after weight loss

scientific article

Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid oxidation in insulin-resistant subjects

scientific article (publication date: October 1998)

Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development

scientific article

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

scientific article published in December 1993

Insulin resistance associated with lower rates of weight gain in Pima Indians

scientific article

Insulin resistance in Pima Indians. A combined effect of genetic predisposition and obesity-related skeletal muscle cell hypertrophy

scientific article published on January 1988

Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle

scientific article

Insulin response of components of whole-body and muscle carbohydrate metabolism in humans

scientific article published on 01 February 1988

Insulin sensitivity in adipocytes from subjects with varying degrees of glucose tolerance

scientific article published in September 1986

Insulin-sensitive tyrosine kinase activity changes in parallel with plasma insulin and glucose concentrations in humans

scientific article

Insulin-sensitive tyrosine kinase: relationship with in vivo insulin action in humans

scientific article published in June 1990

Interrelationships between muscle morphology, insulin action, and adiposity

scientific article published on 01 June 1996

Interstitial insulin concentrations determine glucose uptake rates but not insulin resistance in lean and obese men

scientific article

Lack of IRS-1 codon 513 and 972 polymorphism in Pima Indians

scientific article published on 01 September 1995

Linkage analysis of acute insulin secretion with GLUT2 and glucokinase in Pima Indians and the identification of a missense mutation in GLUT2

scientific article published on 01 April 1994

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

scientific article published on July 1995

Linkage between stature and a region on chromosome 20 and analysis of a candidate gene, bone morphogenetic protein 2

scientific article published on 01 December 1995

Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q

scientific article (publication date: July 2009)

Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians

scientific article

Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians

article

Long-term changes in insulin action and insulin secretion associated with gain, loss, regain and maintenance of body weight

scientific article

Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults

scientific article published on 06 February 2020

Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes

scientific article published in August 2001

Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ.

scientific article published in November 1990

Lower "awake and fed thermogenesis" predicts future weight gain in subjects with abdominal adiposity

scientific article published on 23 August 2013

Lower energy expenditure predicts long-term increases in weight and fat mass

scientific article published on 15 February 2013

Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant

scientific article published on 03 October 2008

Lower sedentary metabolic rate in women compared with men ⬇️

scientific article published on September 1, 1992

Lower total fasting plasma adiponectin concentrations are associated with higher metabolic rates

scientific article

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation

scientific article published on 03 July 2013

Melanocortin 4 receptor gene variation is associated with severe obesity in Pima Indians

scientific article published on 01 October 2004

Metabolic characteristics of individuals with impaired fasting glucose and/or impaired glucose tolerance

scientific article

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity

scientific article published in June 2003

Metabolic factors contributing to increased resting metabolic rate and decreased insulin-induced thermogenesis during the development of type 2 diabetes

scientific article published in August 1999

Metabolic fuels and the capacity for exercise during hypocaloric diet

scientific article published on 01 January 1981

Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes

scientific article

Microarray profiling of skeletal muscle tissues from equally obese, non-diabetic insulin-sensitive and insulin-resistant Pima Indians

scientific article published on 23 August 2002

Missing heritability and GWAS utility

scientific article published on February 2009

Molecular analysis of KCNJ10 on 1q as a candidate gene for Type 2 diabetes in Pima Indians

scientific article (publication date: November 2002)

Molecular and linkage analysis of type-1 protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians

scientific article

Molecular and linkage analysis of type-1 protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians

article

Molecular characterization of the human PEA15 gene on 1q21-q22 and association with type 2 diabetes mellitus in Pima Indians

scientific article (publication date: 4 January 2000)

Multiple disturbances of free fatty acid metabolism in noninsulin-dependent diabetes. Effect of oral hypoglycemic therapy

scientific article

Muscle glycogen synthesis and disposition of infused glucose in humans with reduced rates of insulin-mediated carbohydrate storage

scientific article

Muscle sympathetic nerve activity in response to glucose ingestion. Impact of plasma insulin and body fat.

scientific article published in February 1994

Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians

article

Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: Defining the core HLA variation for North American Paleo-Indians

scientific article published on 06 November 2019

Next generation sequencing for HLA loci in full heritage Pima Indians of Arizona, Part II: HLA-A, -B, and -C with selected non-classical loci at 4-field resolution from whole genome sequences

scientific article published on 17 April 2021

No accumulation of glucose in human skeletal muscle during euglycemic hyperinsulinemia.

scientific article

Non-insulin-dependent diabetes mellitus: what we have learnt from studies carried out among Pima Indians

scientific article published in January 1990

Norepinephrine turnover and energy expenditure in Pima Indian and white men

scientific article published on 01 June 1993

Obesity Triggers: Sequencing the Genome Versus Sequencing the Environment

scientific article

Obesity and insulin resistance: lessons learned from the Pima Indians.

scientific article published on August 1988

Overnutrition induced decrease in insulin action for glucose storage: in vivo and in vitro in man.

scientific article published in February 1986

PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians

scientific article published on 22 July 2008

Palmitate action to inhibit glycogen synthase and stimulate protein phosphatase 2A increases with risk factors for type 2 diabetes

scientific article

Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects

scientific article

Parasympathetic blockade attenuates augmented pancreatic polypeptide but not insulin secretion in Pima Indians

scientific article published in March 2004

Pathogenesis of NIDDM in Pima Indians

scientific article

Pima Indians as a model to study the genetics of NIDDM

scientific article published on 01 April 1992

Plasma adiponectin and endogenous glucose production in humans

scientific article published in December 2003

Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans

scientific article published in June 2002

Plasma concentrations of free triiodothyronine predict weight change in euthyroid persons

scientific article published on February 2007

Plasma concentrations of macrophage migration inhibitory factor are elevated in Pima Indians compared to Caucasians and are associated with insulin resistance

scientific article

Plasma leptin responses to fasting in Pima Indians ⬇️

scientific article published on September 1, 1997

Polymorphism in the 3′ Untranslated Region ofMTG8Is Associated with Obesity in Pima Indian Males ⬇️

scientific article published on May 29, 1998

Polymorphism screening of the insulin receptor-related receptor gene (INSRR) on 1q in Pima Indians

scientific article published in August 2001

Polymorphisms in the oxygen-regulated protein 150 gene (ORP150) are associated with insulin resistance in Pima Indians

scientific article

Positional cloning of an obesity/diabetes susceptibility gene(s) on chromosome 11 in Pima Indians

scientific article published on 01 June 2002

Postabsorptive respiratory quotient and insulin-stimulated glucose storage rate in nondiabetic pima indians are related To glycogen synthase fractional activity in cultured myoblasts ⬇️

scientific article published on May 15, 1998

Potential epigenetic dysregulation of genes associated with MODY and type 2 diabetes in humans exposed to a diabetic intrauterine environment: an analysis of genome-wide DNA methylation

scientific article published on 21 January 2014

Protein targeting to glycogen/PPP1R5: screening of coding and flanking genomic regions for polymorphisms and association analysis with insulin action in Pima Indians

scientific article

Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians

scientific article published on 27 February 2007

Racial difference in body core temperature between Pima Indian and Caucasian men

scientific article published on 01 January 1995

Recent epidemiological contributions to the pathogenesis and etiology of non-insulin dependent diabetes.

scientific article

Reduced early insulin secretion in the etiology of type 2 diabetes mellitus in Pima Indians

scientific article

Reduced insulin secretion: an independent predictor of body weight gain

scientific article published on May 1995

Reduced rate of energy expenditure as a risk factor for body-weight gain

scientific article published in February 1988

Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms

scientific article published on 01 May 2001

Regulation of glycogen synthase and phosphorylase activities by glucose and insulin in human skeletal muscle

scientific article published on July 1987

Regulation of plasma lactate concentration in resting human subjects

scientific article published in August 1990

Relation of the white blood cell count to obesity and insulin resistance: effect of race and gender

scientific article published in November 1995

Relationship Between Insulin Secretion and Insulin Sensitivity and Its Role in Development of Type 2 Diabetes: Beyond the Disposition Index

scientific article published on 18 October 2021

Relationship between degree of obesity and in vivo insulin action in man

scientific article published on 01 March 1985

Relationship between insulin-mediated glucose disposal and lipid metabolism in man.

scientific article

Relationship between obesity and maximal insulin-stimulated glucose uptake in vivo and in vitro in Pima Indians ⬇️

scientific article published on March 1, 1984

Relationship between obesity and maximal insulin-stimulated glucose uptake in vivo and in vitro in man

scientific article published on 01 January 1985

Relationship of genetics, age, and physical fitness to daily energy expenditure and fuel utilization

scientific article published on May 1989

Relationships between insulin secretion, insulin action, and fasting plasma glucose concentration in nondiabetic and noninsulin-dependent diabetic subjects

scientific article

Relatively low plasma leptin concentrations precede weight gain in Pima Indians

scientific article published on February 1997

Risk factors for the development of obesity

scientific article

SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians

scientific article published on 7 August 2011

Salsalate has no effect on insulin secretion but decreases insulin clearance: a randomized, placebo-controlled trial in subjects without diabetes

scientific article published on 12 March 2015

Sensitivity of glucose uptake to insulin in vitro and in vivo in obese Pima Indians

scientific article published on 01 January 1985

Short-term energy balance: relationship with protein, carbohydrate, and fat balances

scientific article published on 01 September 1988

Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man.

scientific article published on August 1987

Skeletal muscle glycogen synthase activity in subjects with non-insulin-dependent diabetes mellitus after glyburide therapy

scientific article published in November 1990

Skeletal muscle membrane lipid composition is related to adiposity and insulin action

scientific article published on December 1995

Skeletal muscle metabolism is a major determinant of resting energy expenditure

scientific article

Skeletal muscle triglyceride levels are inversely related to insulin action

scientific article published in June 1997

Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians.

scientific article

Spontaneous physical activity and obesity: cross-sectional and longitudinal studies in Pima Indians

scientific article published on 01 August 1992

Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians

scientific article published on 29 April 2013

Structure and sequence variation at the human leptin receptor gene in lean and obese Pima Indians

scientific article

Studies of the etiology of obesity in Pima Indians ⬇️

scientific article published on June 1, 1991

Subcutaneous abdominal adipocyte size, a predictor of type 2 diabetes, is linked to chromosome 1q21--q23 and is associated with a common polymorphism in LMNA in Pima Indians.

scientific article

T-cell receptor repertoire variation may be associated with type 2 diabetes mellitus in humans.

scientific article published on 26 September 2015

TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals

scientific article

The 24-h carbohydrate oxidation rate in a human respiratory chamber predicts ad libitum food intake

scientific article

The effect of insulin on net lipid oxidation predicts worsening of insulin resistance and development of type 2 diabetes mellitus

scientific article published on 01 July 2007

The effect of propranolol on free fatty acid mobilization and resting metabolic rate

scientific article published on 01 May 1989

The effects of short-term overfeeding on adipocyte metabolism in Pima Indians

scientific article

The hyperbolic law--a 25-year perspective

scientific article published in February 2005

The interaction of free fatty acids in radioimmunoassays for reverse triiodothyronine

scientific article published on 01 September 1982

The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

scientific article

The pathogenesis of obesity in man: results of studies on Pima Indians

scientific article published on 01 January 1990

The role of glucose allostasis in type 2 diabetes

scientific article published on May 2004

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians

scientific article published in December 2003

The transcribed endosulfine alpha gene is located within a type 2 diabetes-linked region on 1q: sequence and expression analysis in Pima Indians

scientific article

Thermic effect of infused glucose and insulin in man. Decreased response with increased insulin resistance in obesity and noninsulin-dependent diabetes mellitus

scientific article

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene ⬇️

scientific article published on August 10, 1995

Tyrosine kinase activity of skeletal muscle during insulin infusion in humans

scientific article published in July 1992

Use of a High-Density Protein Microarray to Identify Autoantibodies in Subjects with Type 2 Diabetes Mellitus and an HLA Background Associated with Reduced Insulin Secretion

scientific article

VOmax is associated with measures of energy expenditure in sedentary condition but does not predict weight change

scientific article published on 29 October 2018

Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85alpha): preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women

scientific article published on 01 June 1998

Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians

scientific article

Variants in ACAD10 are associated with type 2 diabetes, insulin resistance and lipid oxidation in Pima Indians

scientific article

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article

Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians

scientific article

Variants in hepatocyte nuclear factor 4alpha are modestly associated with type 2 diabetes in Pima Indians.

scientific article

Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article (publication date: December 2007)

Variants in the LEPR gene are nominally associated with higher BMI and lower 24-h energy expenditure in Pima Indians

scientific article

Variants in the interleukin 6 receptor gene are associated with obesity in Pima Indians

scientific article

Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.

scientific article

Variations in the vitamin D-binding protein (Gc locus) are associated with oral glucose tolerance in nondiabetic Pima Indians

scientific article published on 01 August 1998

Where all the glucose doesn't go in non-insulin-dependent diabetes mellitus

scientific article published in January 1990

Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes.

scientific article published on 05 December 2013

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