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List of works by Johannes D Veldhuis

24-hour pulsatile and circadian patterns of cortisol secretion in alcoholic men.

scientific article

A construct of interactive feedback control of the GH axis in the male

scientific article

A highly sensitive growth hormone (GH) enzyme-linked immunosorbent assay uncovers increased contribution of a tonic mode of GH secretion in adults with organic GH deficiency

scientific article published in April 1996

A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty

scientific article

A noninvasive measure of negative-feedback strength, approximate entropy, unmasks strong diurnal variations in the regularity of LH secretion

scientific article published on 11 September 2007

A novel functional interaction between the Sp1-like protein KLF13 and SREBP-Sp1 activation complex underlies regulation of low density lipoprotein receptor promoter function

scientific article

A novel general biophysical model for simulating episodic endocrine gland signaling

scientific article

A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response

scientific article published in March 2002

A pegylated growth hormone receptor antagonist, pegvisomant, does not enter the brain in humans

scientific article

A preponderance of basic luteinizing hormone (LH) isoforms accompanies inappropriate hypersecretion of both basal and pulsatile LH in adolescents with polycystic ovarian syndrome

scientific article

A preponderance of circulating basic isoforms is associated with decreased plasma half-life and biological to immunological ratio of gonadotropin-releasing hormone-releasable luteinizing hormone in obese men.

scientific article published in December 2000

A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and

scientific article published on 28 December 2004

A role for somatomedin C as a differentiating hormone and amplifier of hormone action on ovarian cells: studies with synthetically pure human somatomedin C and swine granulosa cells

scientific article published in July 1985

A super-agonist of growth hormone-releasing hormone causes rapid improvement of nutritional status in patients with chronic kidney disease

scientific article published on 16 December 2009

A tripeptidyl ensemble perspective of interactive control of growth hormone secretion

scientific article

Abrogation by a potent gonadotropin-releasing hormone antagonist of the estrogen/progesterone-stimulated surge-like release of luteinizing hormone and follicle-stimulating hormone in postmenopausal women

scientific article published on October 1, 1992

Accelerated escape from GH autonegative feedback in midpuberty in males: evidence for time-delimited GH-induced somatostatinergic outflow in adolescent boys

scientific article

Acceleration of luteinizing hormone pulse frequency in adolescent girls with a history of central precocious puberty with versus without hyperandrogenism.

scientific article published on 20 June 2007

Actions of cyclic adenosine monophosphate on the cytodifferentiation of ovarian cells: studies in cultured swine granulosa cells using a novel exogenous adenylate cyclase from Bordetella pertussis

scientific article

Actions of endothelin-1 on swine ovarian (granulosa) cells

scientific article published on September 1, 1992

Actions of estradiol on the pulsatile secretion of bioactive luteinizing hormone in man.

scientific article published on January 1986

Actions of estrogen on pulsatile, nyctohemeral, and entropic modes of growth hormone secretion

scientific article

Activation of protein kinase C is coupled to prostaglandin E2 synthesis in swine granulosa cells

scientific article

Activation of somatostatin-receptor subtype-2/-5 suppresses the mass, frequency, and irregularity of growth hormone (GH)-releasing peptide-2-stimulated GH secretion in men.

scientific article published in September 2004

Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes

scientific article published in August 2001

Acute androgen receptor blockade increases luteinizing hormone secretory activity in men.

scientific article

Acute effects of testosterone infusion on the serum luteinizing hormone profile in eumenorrheic and polycystic ovary syndrome adolescents

scientific article published on 30 June 2009

Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and beta-cell mass to age-related insulin resistance in rats

scientific article published on 29 July 2008

Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men.

scientific article

Age and secretagogue type jointly determine dynamic growth hormone responses to exogenous insulin-like growth factor-negative feedback in healthy men.

scientific article published in November 2004

Age and testosterone feedback jointly control the dose-dependent actions of gonadotropin-releasing hormone in healthy men.

scientific article

Age diminishes the testicular steroidogenic response to repeated intravenous pulses of recombinant human LH during acute GnRH-receptor blockade in healthy men.

scientific article published on 30 November 2004

Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men

scientific article published on August 3, 2010

Age in men does not determine gonadotropin-releasing hormone's dose-dependent stimulation of luteinizing hormone secretion under an exogenous testosterone clamp

scientific article

Age-dependent and gender-dependent regulation of hypothalamic-adrenocorticotropic-adrenal axis

scientific article published on 13 March 2013

Age-dependent regression analysis of male gonadal axis

scientific article

Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men.

scientific article published on 12 May 2005

Aging alters feed-forward and feedback linkages between LH and testosterone in healthy men

scientific article published on October 1, 1997

Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women

scientific article published on 05 January 2008

Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp

scientific article published on 19 July 2005

Aging-related adaptations in the corticotropic axis: modulation by gender

scientific article

Alterations in Growth and Body Composition During Puberty: III. Influence of Maturation, Gender, Body Composition, Fat Distribution, Aerobic Fitness, and Energy Expenditure on Nocturnal Growth Hormone Release1

scientific article published on May 1, 1998

Alterations in growth hormone secretion and clearance in adolescent boys with insulin-dependent diabetes mellitus

scientific article

Alterations in luteinizing hormone secretory activity in women with insulin-dependent diabetes mellitus and secondary amenorrhea

scientific article

Alterations in pulsatile luteinizing hormone and follicle-stimulating hormone secretion in idiopathic oligoasthenospermic men: assessment by deconvolution analysis--a clinical research center study

scientific article published in February 1996

Alterations in the pulsatile mode of growth hormone release in men and women with insulin-dependent diabetes mellitus

scientific article published in August 1989

Alterations in the pulsatile properties of circulating growth hormone concentrations during puberty in boys

scientific article

Alterations in the pulsatile properties of gonadotropin secretion in alcoholic men.

scientific article published in May 1988

Altered endogenous growth hormone secretory kinetics and diurnal GH-binding protein profiles in adults with chronic liver disease

scientific article published in September 1995

Altered growth hormone (GH) secretion in vivo and in vitro in the diabetes-prone BB/Worcester rat.

scientific article

Altered growth hormone secretory dynamics in prepubertal males with constitutional delay of growth

scientific article

Altered growth hormone, cortisol, and leptin secretion in healthy elderly persons with sarcopenia and mixed body composition phenotypes

scientific article published in May 2008

Altered morning and nighttime pulsatile corticotropin and cortisol release in polycystic ovary syndrome

scientific article published on February 1, 1998

Altered multihormone synchrony in obese patients with polycystic ovary syndrome

scientific article published on 26 January 2011

Altered neuroendocrine regulation of gonadotropin secretion in women distance runners

scientific article published on September 1985

Altered pulsatile and coordinate secretion of pituitary hormones in aging: evidence of feedback disruption

scientific article

Altered pulsatile gonadotropin signaling in nutritional deficiency in the male

scientific article

Altered temporal organization of plasma insulin oscillations in chronic renal failure

scientific article

Amplified and orderly growth hormone secretion characterizes lean adolescents with polycystic ovary syndrome

scientific article published in August 2002

Amplified nocturnal luteinizing hormone (LH) secretory burst frequency with selective attenuation of pulsatile (but not basal) testosterone secretion in healthy aged men: possible Leydig cell desensitization to endogenous LH signaling--a clinical re

scientific article published on October 1995

Amplitude modulation of a burstlike mode of cortisol secretion subserves the circadian glucocorticoid rhythm

scientific article

Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men.

scientific article

Amplitude, but not frequency, modulation of adrenocorticotropin secretory bursts gives rise to the nyctohemeral rhythm of the corticotropic axis in man.

scientific article

An amplitude-specific divergence in the pulsatile mode of growth hormone (GH) secretion underlies the gender difference in mean GH concentrations in men and premenopausal women

scientific article published in July 1996

An ensemble model of the male gonadal axis: illustrative application in aging men.

scientific article

An overview of computer algorithms for deconvolution-based assessment of in vivo neuroendocrine secretory events.

scientific article

Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes

scientific article published on 14 October 2004

Analysis of nonequilibrium dynamics of bound, free, and total plasma ligand concentrations over time following nonlinear secretory inputs: kinetics of two or more hormones pulsed into compartments containing multiple variable-affinity binding protei

scientific article

Analysis of the copulsatility of anterior pituitary hormones

scientific article

Analysis of the impact of intravenous LH pulses versus continuous LH infusion on testosterone secretion during GnRH-receptor blockade

scientific article

Analytical construct of reversible desensitization of pituitary-testicular signaling: illustrative application in aging

scientific article published on November 17, 2010

Analytical methods for evaluating episodic secretory activity within neuroendocrine axes

scientific article

Analyzing pulsatile endocrine data in patients with chronic renal failure: a brief review of deconvolution techniques

scientific article

Androgen-receptor blockade enhances pulsatile luteinizing hormone production in late pubertal males: evidence for a hypothalamic site of physiologic androgen feedback action

scientific article

Anesthesia rapidly suppresses insulin pulse mass but enhances the orderliness of insulin secretory process

scientific article published in July 2001

Angiotensin II induces calcium release in a subpopulation of single ovarian (granulosa) cells

scientific article published on October 1, 1991

Apparently complete restoration of normal daily adrenocorticotropin, cortisol, growth hormone, and prolactin secretory dynamics in adults with Cushing's disease after clinically successful transsphenoidal adenomectomy

scientific article

Appraising the instantaneous secretory rates of luteinizing hormone and testosterone in response to selective mu opiate receptor blockade in late pubertal boys

scientific article published in July 1987

Are estrogens of import to primate/human ovarian folliculogenesis?

scientific article

Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men.

scientific article

Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men.

scientific article published in June 2001

Assessment of insulin secretion in relatives of patients with type 2 (non-insulin-dependent) diabetes mellitus: evidence of early beta-cell dysfunction

scientific article

Assessment of stimulated and spontaneous adrenocorticotropin secretory dynamics identifies distinct components of cortisol feedback inhibition in healthy humans

scientific article

Attenuated pulsatile release of prolactin in men with insulin-dependent diabetes mellitus

scientific article

Attenuation of luteinizing hormone secretory burst amplitude as a proximate basis for the hypoandrogenism of healthy aging in men

scientific article published on September 1, 1992

Augmentation of growth hormone secretion during puberty: evidence for a pulse amplitude-modulated phenomenon

scientific article published on March 1987

Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men

scientific article published on April 1, 1992

Basal, pulsatile, entropic (patterned), and spiky (staccato-like) properties of ACTH secretion: impact of age, gender, and body mass index

scientific article

Basal, pulsatile, entropic, and 24-hour rhythmic features of secondary hyperprolactinemia due to functional pituitary stalk disconnection mimic tumoral (primary) hyperprolactinemia

scientific article

Bedtime administration of NN2211, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes

scientific article published in February 2002

Beta1-adrenergic blockade augments pulsatile PTH secretion in humans

scientific article published in December 2003

Biophysical modeling of sensitivity and positive accuracy of detecting episodic endocrine signals

scientific article

Bipotential actions of estrogen on progesterone biosynthesis by ovarian cells. I. Relation of estradiol's inhibitory actions to cholesterol and progestin metabolism in cultured swine granulosa cells

scientific article published on May 1985

Calcium ions positively modulate follicle-stimulating hormone- and exogenous cyclic 3',5'-adenosine monophosphate-driven transcription of the P450(scc) gene in porcine granulosa cells

scientific article

Calcium-Sensing by Parathyroid Glands in Secondary Hyperparathyroidism1

scientific article published on August 1, 1998

Cellular basis for follicle-stimulating hormone-stimulated calcium signaling in single rat Sertoli cells: possible dissociation from effects of adenosine 3',5'-monophosphate

scientific article

Changes in pituitary function with ageing and implications for patient care

scientific article published on 26 February 2013

Characterization of attenuated proestrous luteinizing hormone surges in middle-aged rats by deconvolution analysis

scientific article published in December 1998

Characterization of pulsatile secretion and clearance of plasma cortisol in premature and term neonates using deconvolution analysis

scientific article

Chronic glucocorticoid treatment alters spontaneous pulsatile parathyroid hormone secretory dynamics in human subjects

scientific article published in February 2005

Circadian, ultradian, and episodic release of beta-endorphin in men, and its temporal coupling with cortisol

scientific article

Clinical pathophysiology of the somatotropic (GH) axis in adults.

scientific article published on December 1992

Clinical review 171: The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations

scientific article

Cluster analysis: a simple, versatile, and robust algorithm for endocrine pulse detection

scientific article

Combined deficits in the somatotropic and gonadotropic axes in healthy aging men: an appraisal of neuroendocrine mechanisms by deconvolution analysis

scientific article

Combined inhibition of types I and II 5 alpha-reductase selectively augments the basal (nonpulsatile) mode of testosterone secretion in young men.

scientific article published on 5 April 2005

Comparative Pharmacokinetics of Three Doses of Percutaneous Dihydrotestosterone Gel in Healthy Elderly Men–A Clinical Research Center Study1

scientific article published on August 1, 1998

Comparative assessments of objective peak-detection algorithms. II. Studies in men.

scientific article

Comparison of Four Computerized Models to Estimate 24-Hour Growth Hormone Secretion in Girls with Turner’s Syndrome

scientific article published on January 1, 1992

Comparison of Pulsatile Luteinizing Hormone Secretion Between Prepubertal Children and Young Adults: Evidence for a Mass/Amplitude-Dependent Difference Without Gender or Day/Night Contrasts1

scientific article published on September 1, 1997

Compensatory growth of broiler chickens is associated with an enhanced pulsatile growth hormone (GH) secretion: Preferential amplification of GH secretory burst mass

scientific article published on July 1, 1997

Complementary secretagogue pairs unmask prominent gender-related contrasts in mechanisms of growth hormone pulse renewal in young adults

scientific article

Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp

scientific article published on April 5, 2011

Composite model of time-varying appearance and disappearance of neurohormone pulse signals in blood

scientific article

Concerted regulation of low density lipoprotein receptor gene expression by follicle-stimulating hormone and insulin-like growth factor I in porcine granulosa cells: promoter activation, messenger ribonucleic acid stability, and sterol feedback

scientific article

Concerted regulation of steroidogenic acute regulatory gene expression by luteinizing hormone and insulin (or insulin-like growth factor I) in primary cultures of porcine granulosa-luteal cells

scientific article

Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase a, phosphatidylinositol 3-kinase, and mitogen-act

scientific article

Concordant induction of rapid in vivo pulsatile insulin secretion by recurrent punctuated glucose infusions

scientific article published on January 2000

Contemporary aspects of discrete peak-detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men.

scientific article

Contemporary aspects of discrete peak-detection algorithms. II. The paradigm of the luteinizing hormone pulse signal in women

scientific article

Contemporary insights into the regulation of luteinizing hormone secretion in man.

scientific article

Contemporary tools for the analysis of episodic growth hormone secretion and clearance in vivo

scientific article

Continuous 24-hour intravenous infusion of recombinant human growth hormone (GH)-releasing hormone-(1-44)-amide augments pulsatile, entropic, and daily rhythmic GH secretion in postmenopausal women equally in the estrogen-withdrawn and estrogen-supp

scientific article

Continuous positive airway pressure increases pulsatile growth hormone secretion and circulating insulin-like growth factor-1 in a time-dependent manner in men with obstructive sleep apnea: a randomized sham-controlled study

scientific article

Contrasting negative-feedback control of endogenously driven and exercise-stimulated pulsatile growth hormone secretion in women and men.

scientific article published in February 2004

Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults

scientific article published in December 2004

Control of LH secretory-burst frequency and interpulse-interval regularity in women

scientific article

Coordinate Developmental Expression of Genes Regulating Sterol Economy and Cholesterol Side-Chain Cleavage in the Porcine Ovary1

scientific article published on August 1, 1997

Coordinate activation of the corticotropic axis by insulin-induced hypoglycemia: simultaneous estimates of beta-endorphin, adrenocorticotropin and cortisol secretion and disappearance in normal men.

scientific article published in June 1993

Correlation of parameters of urinary excretion with serum osmolality among patients with psychosis, intermittent hyponatremia, and polydipsia (PIP syndrome)

scientific article published on January 1, 1988

Corticotropic axis drive of overnight cortisol secretion is suppressed in adolescents and young adults with type 1 diabetes mellitus

scientific article

Corticotropin secretory dynamics in humans under low glucocorticoid feedback

scientific article

Cortisol and GH secretory dynamics, and their interrelationships, in healthy aged women and men.

scientific article published in April 2001

Cortisol feedback state governs adrenocorticotropin secretory-burst shape, frequency, and mass in a dual-waveform construct: time of day-dependent regulation

scientific article published on 3 July 2003

Current concepts on ultradian rhythms of luteinizing hormone secretion in the human

scientific article published on November 1996

Deconvolution analysis as a hormone pulse-detection algorithm

scientific article

Deconvolution analysis of bioassayable LH secretion and half‐life in men with idiopathic oligoasthenospermia

scientific article published on April 1, 1997

Deconvolution analysis of rapid insulin pulses before and after six weeks of continuous subcutaneous administration of glucagon-like peptide-1 in elderly patients with type 2 diabetes

scientific article published on 9 August 2005

Decrease in beta-cell mass leads to impaired pulsatile insulin secretion, reduced postprandial hepatic insulin clearance, and relative hyperglucagonemia in the minipig

scientific article published in September 2001

Decreased metabolic clearance of endogenous growth hormone and specific alterations in the pulsatile mode of growth hormone secretion occur in prepubertal girls with Turner's syndrome. Genentech Collaborative Group

scientific article

Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice

scientific article published in March 2017

Dehydroepiandrosterone supplementation in women with adrenal failure: impact on twenty-four hour GH secretion and IGF-related parameters

scientific article published on April 2004

Demonstration of a lack of racial difference in secretion of growth hormone despite a racial difference in bone mineral density in premenopausal women--a Clinical Research Center study

scientific article published in March 1996

Determinants of GH-releasing hormone and GH-releasing peptide synergy in men

scientific article published on 24 February 2009

Determinants of dual secretagogue drive of burst-like growth hormone secretion in premenopausal women studied under a selective estradiol clamp

scientific article

Deterministic construct of amplifying actions of ghrelin on pulsatile growth hormone secretion

scientific article

Developmentally delimited emergence of more orderly luteinizing hormone and testosterone secretion during late prepuberty in boys

scientific article

Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets

scientific article

Dietary patterns, eating behaviors, and bone mineral density in women runners

scientific article published on October 1, 1992

Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women.

scientific article published on 14 June 2018

Differential effects of pulsatile versus continuous follicle-stimulating hormone delivery on the production of cyclic adenosine 5'-monophosphates and the accumulation of cytochrome P450 cholesterol side-chain cleavage enzyme mRNA in perifused porcin

scientific article published on July 1, 1995

Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay

scientific article published on November 1, 1995

Differential pulsatile secretagogue control of GH secretion in healthy men.

scientific article published on 13 March 2013

Differential responses of biologically active luteinizing hormone secretion in older versus young men to interruption of androgen negative feedback

scientific article

Differential sex steroid negative feedback regulation of pulsatile follicle-stimulating hormone secretion in healthy older men: deconvolution analysis and steady-state sex-steroid hormone infusions in frequently sampled healthy older individuals

scientific article

Diminished and irregular TSH secretion with delayed acrophase in patients with Cushing's syndrome

scientific article published on 17 August 2009

Direct Actions of 17β-Estradiol on Progesterone Production by Highly Differentiated Porcine Gram∧losa Cells in Vitro. II. Regulatory Interactions of Estradiol with Luteinizing Hormone and Cyclic Nucleotides*

scientific article published on August 1, 1981

Direct measurement of pulsatile insulin secretion from the portal vein in human subjects

scientific article published in December 2000

Disordered adrenocorticotropin secretion in women with major depression

scientific article published on 14 February 2006

Disparate serum free testosterone concentrations and degrees of hypothalamo-pituitary-luteinizing hormone suppression are achieved by continuous versus pulsatile intravenous androgen replacement in men: a clinical experimental model of ketoconazole-

scientific article published in July 1997

Disruption of the joint synchrony of luteinizing hormone, testosterone, and androstenedione secretion in adolescents with polycystic ovarian syndrome

scientific article

Disruption of the pulsatile and entropic modes of insulin release during an unvarying glucose stimulus in elderly individuals

scientific article published in June 1999

Disruption of the synchronous secretion of leptin, LH, and ovarian androgens in nonobese adolescents with the polycystic ovarian syndrome

scientific article

Disruption of the young-adult synchrony between luteinizing hormone release and oscillations in follicle-stimulating hormone, prolactin, and nocturnal penile tumescence (NPT) in healthy older men.

scientific article

Dissociation of pulsatile cortisol and adrenocorticotropin secretion in fetal sheep during late gestation

scientific article published on May 1, 1992

Distinct Metabolic Surrogates Predict Basal and Rebound GH Secretion after Glucose Ingestion in Men

scientific article published on April 3, 2012

Distinctive inhibitory mechanisms of age and relative visceral adiposity on growth hormone secretion in pre- and postmenopausal women studied under a hypogonadal clamp

scientific article published on 9 August 2005

Diurnal variation in the elimination rate of human growth hormone (GH): the half-life of serum GH is prolonged in the evening, and affected by the source of the hormone, as well as by body size and serum estradiol

scientific article published in July 1993

Divergent effects of short term glucocorticoid excess on the gonadotropic and somatotropic axes in normal men

scientific article published on January 1, 1992

Divergent gonadotropin-gonadal dose-responsive coupling in healthy young and aging men

scientific article published on October 30, 2003

Divergent influences of the structurally dissimilar calcium entry blockers, diltiazem and verapamil, on thyrotropin- and gonadotropin-releasing hormone-stimulated anterior pituitary hormone secretion in man.

scientific article

Dose-response downregulation within the span of single interpulse intervals

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Doα-Adrenergic Mechanisms Regulate Spontaneous or Opiate-Modulated Pulsatile Luteinizing Hormone Secretion in Man?*

scientific article published on December 1, 1983

Dual actions of phorbol ester on cytochrome P450 cholesterol side-chain cleavage messenger ribonucleic acid accumulation in porcine granulosa cells

scientific article

Dual defects in pulsatile growth hormone secretion and clearance subserve the hyposomatotropism of obesity in man.

scientific article

Dual secretagogue drive of burst-like growth hormone secretion in postmenopausal compared with premenopausal women studied under an experimental estradiol clamp

scientific article published in September 2004

Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality

scientific article published in April 2010

Dynamic testosterone responses to near-physiological LH pulses are determined by the time pattern of prior intravenous LH infusion

scientific article published on July 17, 2012

Dynamics of 24-hour endogenous cortisol secretion and clearance in primary hypothyroidism assessed before and after partial thyroid hormone replacement

scientific article published in January 1990

Dynamics of pulsatile prolactin release during the postpartum lactational period

scientific article

Early manifestations of "sick euthyroid" syndrome in patients with compensated chronic heart failure

scientific article published in June 2001

Effect of antalarmin, a novel corticotropin-releasing hormone antagonist, on the dynamic function of the preterm ovine fetal hypothalamo-pituitary-adrenal axis

scientific article published in July 2002

Effect of endogenous opioid blockade on the amplitude and frequency of pulsatile luteinizing hormone secretion in normal men.

scientific article published in April 1982

Effect of pioglitazone on glucose metabolism and luteinizing hormone secretion in women with polycystic ovary syndrome

scientific article published on 16 June 2006

Effect of the GH secretagogue L-163,255 and restricted feeding time on GH pulsatility in the rat.

scientific article published in July 2002

Effects of Testosterone Administration on Nocturnal Cortisol Secretion in Healthy Older Men

scientific article published on July 30, 2010

Effects of Toremifene, a Selective Estrogen Receptor Modulator, on Spontaneous and Stimulated GH Secretion, IGF-I, and IGF-Binding Proteins in Healthy Elderly Subjects

scientific article published on 28 December 2017

Effects of age on the irregularity of LH and FSH serum concentrations in women and men

scientific article published on November 1, 1997

Effects of continuous versus intermittent exercise, obesity, and gender on growth hormone secretion

scientific article

Effects of diets enriched in saturated (palmitic), monounsaturated (oleic), or trans (elaidic) fatty acids on insulin sensitivity and substrate oxidation in healthy adults

scientific article published in August 2002

Effects of fasting on physiologically pulsatile insulin release in healthy humans

scientific article published in February 2002

Effects of metformin on inappropriate LH release in women with polycystic ovarian syndrome and insulin resistance

scientific article

Effects of neurokinin B administration on reproductive hormone secretion in healthy men and women

scientific article published on 20 December 2013

Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations

scientific article published on January 1987

Effects of transdermal testosterone gel or an aromatase inhibitor on serum concentration and pulsatility of growth hormone in older men with age-related low testosterone

scientific article published on 19 January 2017

Elements in the pathophysiology of diminished growth hormone (GH) secretion in aging humans

scientific article published on August 1, 1997

Elevated growth hormone secretory rate in premature infants: deconvolution analysis of pulsatile growth hormone secretion in the neonate

scientific article published on September 1, 1992

Endocrine and metabolic effects of growth hormone (GH) compared with GH-releasing peptide, thyrotropin-releasing hormone, and insulin infusion in a rabbit model of prolonged critical illness

scientific article published on 9 October 2003

Endocrine control of body composition in infancy, childhood, and puberty

scientific article

Endocrine control of steroidogenesis in granulosa cells

scientific article published on January 1, 1992

Endocrine function after spontaneous infarction of the human pituitary: report, review, and reappraisal

scientific article published on January 1980

Endogenous ACTH concentration-cortisol secretion dose analysis unmasks decreased ACTH potency in Cushing's disease with restoration after successful pituitary adenomectomy

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Endogenous ACTH concentration-dependent drive of pulsatile cortisol secretion in the human

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Endogenous Estrogen Regulates Somatostatin-Induced Rebound GH Secretion in Postmenopausal Women

scientific article published on 26 July 2016

Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass

scientific article published on February 1, 1992

Endogenous opiates participate in the regulation of pulsatile luteinizing hormone release in an unopposed estrogen milieu: studies in estrogen-replaced, gonadectomized patients with testicular feminization.

scientific article

Enhanced Coupling Within Gonadotropic and Adrenocorticotropic Axes by Moderate Exercise in Healthy Men.

scientific article published on 27 April 2017

Enhanced sensitivity growth hormone (GH) chemiluminescence assay reveals lower postglucose nadir GH concentrations in men than women

scientific article

Episodic secretion of parathyroid hormone in postmenopausal women: assessment by deconvolution analysis and approximate entropy

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Erosion of endogenous testosterone-driven negative feedback on pulsatile luteinizing hormone secretion in healthy aging men.

scientific article published in November 2004

Estimation of daily cortisol production and clearance rates in normal pubertal males by deconvolution analysis

scientific article

Estimation of the size and shape of GH secretory bursts in healthy women using a physiological estradiol clamp and variable-waveform deconvolution model

scientific article published on 30 May 2007

Estradiol Supplementation Enhances Submaximal Feed-Forward Drive of Growth Hormone (GH) Secretion by Recombinant Human GH-Releasing Hormone-1,44-Amide in a Putatively Somatostatin-Withdrawn Milieu

scientific article published on November 1, 2003

Estradiol amplifies the amount of luteinizing hormone (LH) secreted in response to increasing doses of gonadotropin-releasing hormone by specifically augmenting the duration of evoked LH secretory events and hence their mass

scientific article

Estradiol potentiates ghrelin-stimulated pulsatile growth hormone secretion in postmenopausal women

scientific article published on 27 June 2006

Estradiol regulates GH-releasing peptide's interactions with GH-releasing hormone and somatostatin in postmenopausal women

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Estradiol supplementation in postmenopausal women attenuates suppression of pulsatile growth hormone secretion by recombinant human insulin-like growth factor type I

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Estradiol supplementation in postmenopausal women doubles rebound-like release of growth hormone (GH) triggered by sequential infusion and withdrawal of somatostatin: evidence that estrogen facilitates endogenous GH-releasing hormone drive

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Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin-like growth factor-I-enforced suppression of endogenously driven GH release in postmenopausal women

scientific article published in March 2004

Estradiol, but not testosterone, heightens cortisol-mediated negative feedback on pulsatile ACTH secretion and ACTH approximate entropy in unstressed older men and women

scientific article

Estrogen elevates the peak overnight production rate of acylated ghrelin

scientific article published on 12 August 2008

Estrogen regulates low density lipoprotein metabolism by cultured swine granulosa cells

scientific article published in October 1985

Estrogen regulates the gonadotropin-releasing hormone-stimulated secretion of biologically active luteinizing hormone

scientific article

Estrogen supplementation selectively enhances hypothalamo-pituitary sensitivity to ghrelin in postmenopausal women

scientific article published on 08 July 2008

Estrogen-like potentiation of ghrelin-stimulated GH secretion by fulvestrant, a putatively selective ER antagonist, in postmenopausal women

scientific article

Estrogenic modulation of the gonadotropin-releasing hormone-stimulated secretory activity of the gonadotrope and lactotrope in prepubertal females with Turner's syndrome

scientific article published in December 1991

Evaluation of pulsatile patterns of growth hormone release in humans: A brief review

scientific article

Evidence for attenuation of hypothalamic gonadotropin-releasing hormone (GnRH) impulse strength with preservation of GnRH pulse frequency in men with chronic renal failure

scientific article

Evidence that androgen negative feedback regulates hypothalamic gonadotropin-releasing hormone impulse strength and the burst-like secretion of biologically active luteinizing hormone in men

scientific article published on June 1, 1992

Exaggerated 17-hydroxyprogesterone response to intravenous infusions of recombinant human LH in women with polycystic ovary syndrome

scientific article

Exercise training at and above the lactate threshold in previously untrained women

scientific article published in April 1992

Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in asian and caucasian men.

scientific article

Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism

scientific article published on 19 April 2013

Expression of parathyroid hormone-related peptide (PTH-rp) and its receptorin the porcine ovary: regulation by transforming growth factor-beta and possible paracrine effects of granulosa cell PTH-rp secretion on theca cells

scientific article

Facilitative actions of the protein kinase-C effector system on hormonally stimulated adenosine 3',5'-monophosphate production by swine luteal cells

scientific article

Factors other than sex steroids modulate GHRH and GHRP-2 efficacies in men: evaluation using a GnRH agonist/testosterone clamp

scientific article published on 07 April 2009

Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes

scientific article published in August 2000

Fasting Suppresses Pulsatile Luteinizing Hormone (LH) Secretion and Enhances Orderliness of LH Release in Young but Not Older Men1

scientific article published on June 1, 1998

Fasting as a metabolic stress paradigm selectively amplifies cortisol secretory burst mass and delays the time of maximal nyctohemeral cortisol concentrations in healthy men.

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Feedback on LH in Testosterone-Clamped Men Depends on the Mode of Testosterone Administration and Body Composition

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Fetal growth velocity, size in early life and adolescence, and prediction of bone mass: association to the GH-IGF axis

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Five-day pulsatile gonadotropin-releasing hormone administration unveils combined hypothalamic-pituitary-gonadal defects underlying profound hypoandrogenism in men with prolonged critical illness

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Follicle-Stimulating Hormone Increases Concentrations of Messenger Ribonucleic Acid Encoding Cytochrome P450 Cholesterol Side-Chain Cleavage Enzyme in Primary Cultures of Porcine Granulosa Cells*

scientific article published on April 1, 1991

Follicle-stimulating hormone evokes an increase in intracellular free calcium ion concentrations in single ovarian (granulosa) cells

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Follicle-stimulating hormone regulates low density lipoprotein metabolism by swine granulosa cells

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Food deprivation and feeding of broiler chickens is associated with rapid and interdependent changes in the somatotrophic and thyrotrophic axes

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Gender and sexual maturation-dependent contrasts in the neuroregulation of growth hormone secretion in prepubertal and late adolescent males and females--a general clinical research center-based study

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Gender determines ACTH recovery from hypercortisolemia in healthy older humans

scientific article published on 25 September 2013

Gender governs the relationship between exercise intensity and growth hormone release in young adults

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Gender modulates sequential suppression and recovery of pulsatile growth hormone secretion by physiological feedback signals in young adults

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Gender, age, body mass index, and IGF-I individually and jointly determine distinct GH dynamics: analyses in one hundred healthy adults

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Gender, sex-steroid, and secretagogue-selective recovery from growth hormone-induced feedback in older women and men

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Ghrelin potentiates growth hormone secretion driven by putative somatostatin withdrawal and resists inhibition by human corticotropin-releasing hormone

scientific article published on 14 March 2006

Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion

scientific article published in January 1998

Glucocorticoid induced insulin resistance impairs basal but not glucose entrained high-frequency insulin pulsatility in humans

scientific article published in January 2002

Glucose Ingestion Selectively Amplifies ACTH and Cortisol Secretory-Burst Mass and Enhances Their Joint Synchrony in Healthy Men

scientific article published on July 13, 2011

Glucose ingestion acutely lowers pulsatile LH and basal testosterone secretion in men.

scientific article published on 17 January 2012

Glucose relays information regarding nutritional status to the neural circuits that control the somatotropic, corticotropic, and gonadotropic axes in adult male rhesus macaques

scientific article published in February 2002

Glucose stimulates pulsatile insulin secretion from human pancreatic islets by increasing secretory burst mass: dose-response relationships

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GnRH antagonists suppress prolactin release in non-human primates

scientific article published on April 1, 1992

Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men

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Graded Testosterone Infusions Distinguish Gonadotropin Negative-Feedback Responsiveness in Asian and White Men—A Clinical Research Center Study1

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Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow

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Growth Hormone Dynamics in Healthy Adults Are Related to Age and Sex and Strongly Dependent on Body Mass Index

scientific article published on 28 July 2015

Growth hormone (GH) secretion, GH-dependent gene expression, and sexually dimorphic body growth in young rats with chronic renal failure

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Growth hormone and growth hormone-related mRNA in uremic rats: effect of a growth hormone secretagogue

scientific article published on 7 June 2002

Growth hormone and prolactin are secreted more irregularly in patients with Cushing's disease

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Growth hormone release during acute and chronic aerobic and resistance exercise: recent findings

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Growth hormone response to graded exercise intensities is attenuated and the gender difference abolished in older adults

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Growth hormone secretion and bone mineral density in prepubertal black and white boys

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Growth hormone secretion in primary adrenal Cushing's syndrome is disorderly and inversely correlated with body mass index

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Growth hormone-releasing hormone and growth hormone-releasing peptide as potential therapeutic modalities

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Half-time of endogenous growth hormone (GH) disappearance in normal man after stimulation of GH secretion by GH-releasing hormone and suppression with somatostatin

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Homeostatic joint amplification of pulsatile and 24-hour rhythmic cortisol secretion by fasting stress in midluteal phase women: concurrent disruption of cortisol-growth hormone, cortisol-luteinizing hormone, and cortisol-leptin synchrony

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Hormone pulsatility discrimination via coarse and short time sampling

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Hormone secretion by pituitary adenomas is characterized by increased disorderliness and spikiness but more regular pulsing

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How does one get at glandular secretion, when only hormone concentrations are measured?

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Human GH pulsatility: an ensemble property regulated by age and gender

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Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets

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Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion

scientific article published on 19 August 2008

Hypophyseal-portal somatostatin (SRIH) and jugular venous growth hormone secretion in the conscious unrestrained ewe.

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Hypothalamo-Pituitary Disconnection of the Late-Gestation Ovine Fetus Results in Profound Changes in Cortisol Secretion that Are Not Reflected in Commensurate Changes in Adrenocorticotropin Secretion*

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Hypothalamo-pituitary-adrenal axis after a single epidural triamcinolone injection

scientific article published on 3 July 2017

Identification of Stimulatory and Inhibitory Inputs to the Hypothalamic‐Pituitary‐Adrenal Axis During Hypoglycaemia or Transport In Ewes

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Immunologic and mass-spectrometric estimates of SHBG concentrations in healthy women

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Immunological and mass spectrometric assays of SHBG: consistent and inconsistent metabolic associations in healthy men

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Immunoreactive and bioactive luteinizing hormone in pubertal patients with chronic renal failure. Cooperative Study Group on Pubertal Development in Chronic Renal Failure

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Impact of Adiposity and Fat Distribution on the Dynamics of Adrenocorticotropin and Cortisol Rhythms

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Impact of age on cortisol secretory dynamics basally and as driven by nutrient-withdrawal stress

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Impact of age, sex and body mass index on cortisol secretion in 143 healthy adults

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Impact of intensive venous sampling on characterization of pulsatile GH release

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Impact of pulsatility on the ensemble orderliness (approximate entropy) of neurohormone secretion

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Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans

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Impact of uraemia on food efficiency and the pulsatile mode of growth hormone secretion in rats

scientific article published on September 1, 1995

Impact of uremia on female reproductive cyclicity, ovulation, and luteinizing hormone in the rat.

scientific article published in August 2000

Impaired adrenergic- and corticotropic-axis outflow during exercise in chronic obstructive pulmonary disease

scientific article published on 31 May 2011

Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals

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In Situ Amplification of the Cytochrome P-450 Cholesterol Side-Chain Cleavage Enzyme mRNA in Single Porcine Granulosa Cells by IGF-1 and FSH Acting Alone or in Concert

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In ovo treatment with an aromatase inhibitor masculinizes postnatal hormone levels, abdominal fat pad content, and GH pulsatility in broiler chickens

scientific article published on March 1, 1998

In vivo alterations in the gonadotropin-releasing hormone pulse generator and the secretion and clearance of luteinizing hormone in the uremic castrate rat.

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In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection. I. The LH pulse signal

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In vivo biological validation and biophysical modeling of the sensitivity and positive accuracy of endocrine peak detection. II. The follicle-stimulating hormone pulse signal

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In vivo dynamics of luteinizing hormone secretion and clearance in man: assessment by deconvolution mechanics

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Increase in daily LH secretion in response to short-term calorie restriction in obese women with PCOS.

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Increased basal and pulsatile secretion of FSH and LH in young men with 47,XXY or 46,XX karyotypes

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Increased disorderliness and amplified basal and pulsatile aldosterone secretion in patients with primary aldosteronism

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Increased hGH production rate after low-dose estrogen therapy in prepubertal girls with Turner's syndrome

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Increased potency and sustained suppressive actions of a new gonadotropin-releasing hormone (GnRH) antagonist peptide in man.

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Increased pulsatility, process irregularity, and nocturnal trough concentrations of growth hormone in amenorrheic compared to eumenorrheic athletes

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Increasing LH pulsatility in women with hypothalamic amenorrhoea using intravenous infusion of Kisspeptin-54.

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Induction of beta-cell rest by a Kir6.2/SUR1-selective K(ATP)-channel opener preserves beta-cell insulin stores and insulin secretion in human islets cultured at high (11 mM) glucose

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Infantile hypercalcemia with subcutaneous fat necrosis: Endocrine studies

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Insulin drives transcriptional activity of the CYP17 gene in primary cultures of swine theca cells

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Insulin regulates low density lipoprotein metabolism by swine granulosa cells

scientific article published on June 1986

Insulin-dependent diabetes mellitus and menstrual dysfunction

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Insulin-like growth factor type I (somatomedin-C) stimulates high density lipoprotein (HDL) metabolism and HDL-supported progesterone biosynthesis by swine granulosa cells in vitro

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Insulin-like growth factor type I increases concentrations of messenger ribonucleic acid encoding cytochrome P450 cholesterol side-chain cleavage enzyme in primary cultures of porcine granulosa cells

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Integrating GHS into the Ghrelin System

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Intensified rates of venous sampling unmask the presence of spontaneous, high-frequency pulsations of luteinizing hormone in man.

scientific article published in July 1984

Intensive venous sampling paradigms disclose high frequency adrenocorticotropin release episodes in normal men.

scientific article published in November 1990

Interactions Between Neurokinin B and Kisspeptin in Mediating Estrogen Feedback in Healthy Women

scientific article published on 16 September 2016

Interactions among endocrine control systems in the regulation of ovarian function

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Interactions of protein kinase C with receptor- and non-receptor-mediated cyclic AMP generation in swine granulosa cells

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Interictal and postictal alterations of pulsatile secretions of luteinizing hormone in temporal lobe epilepsy in men.

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Interleukins 6 and 8 and abdominal fat depots are distinct correlates of lipid moieties in healthy pre- and postmenopausal women

scientific article published on 22 July 2016

Intrahepatic transplanted islets in humans secrete insulin in a coordinate pulsatile manner directly into the liver

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Investigating the KNDy Hypothesis in Humans by Coadministration of Kisspeptin, Neurokinin B, and Naltrexone in Men.

scientific article published on 05 July 2016

Involvement of Sp1 and SREBP-1a in transcriptional activation of the LDL receptor gene by insulin and LH in cultured porcine granulosa-luteal cells

scientific article published on 2 March 2004

Irregular circulating insulin concentrations in type 2 diabetes mellitus: an inverse relationship between circulating free fatty acid and the disorderliness of an insulin time series in diabetic and healthy individuals

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Is growth saltatory? The usefulness and limitations of frequency distributions in analyzing pulsatile data

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Is the calcium signal induced by follicle-stimulating hormone in swine granulosa cells mediated by adenosine cyclic 3',5'-monophosphate-dependent protein kinase?

scientific article published on April 1, 1992

Is there a physiological role for gonadotrophin oligosaccharide heterogeneity in humans? III. Luteinizing hormone heterogeneity: a medical physiologist's perspective

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Joint basal and pulsatile hypersecretory mechanisms drive the monotropic follicle-stimulating hormone (FSH) elevation in healthy older men: concurrent preservation of the orderliness of the FSH release process: a general clinical research center stu

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Joint mechanisms of impaired growth-hormone pulse renewal in aging men.

scientific article published on 5 April 2005

Joint pituitary-hypothalamic and intrahypothalamic autofeedback construct of pulsatile growth hormone secretion

scientific article published on 17 July 2003

Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion

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Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: indirect evidence for disruption of feedback regulation within the GH-insulin-like growth factor I axis

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Kinetics of removal of intravenous testosterone pulses in normal men.

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Logistic model of glucose-regulated C-peptide secretion: hysteresis pathway disruption in impaired fasting glycemia

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Long-term endurance training alters the hypothalamic-pituitary axes for gonadotropins and growth hormone.

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Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men.

scientific article published on 5 June 2007

Longitudinal changes in growth hormone secretory process irregularity assessed transpubertally in healthy boys

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Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes

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Low amplitude and disorderly spontaneous growth hormone release in obese women with or without polycystic ovary syndrome

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Low basal and persistent pulsatile growth hormone secretion are revealed in normal and hyposomatotropic men studied with a new ultrasensitive chemiluminescence assay

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Low-dose T(3) improves the bed rest model of simulated weightlessness in men and women

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Luteinizing Hormone (LH) Stimulates Both Intracellular Calcium Ion ([Ca2+]i) Mobilization and Transmembrane Cation Influx in Single Ovarian (Granulosa) Cells: Recruitment as a Cellular Mechanism of LH-[Ca2+]i Dose Response*

scientific article published on August 1, 1998

Luteinizing hormone (LH) drives diverse intracellular calcium second messenger signals in isolated porcine ovarian thecal cells: preferential recruitment of intracellular Ca2+ oscillatory cells by higher concentrations of LH.

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Management of amenorrhea.

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Maturation of spontaneous and agonist-induced uterine contractions in the peripartum mouse uterus

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Maturation of the regulation of growth hormone secretion in young males with hypogonadotropic hypogonadism pharmacologically exposed to progressive increments in serum testosterone

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Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein

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Mechanism(s) by which activation of protein kinase C is coupled to prostacyclin synthesis in granulosa cells

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Mechanisms and biological significance of pulsatile hormone secretion. Symposium proceedings. London, United Kingdom, 2-4 March 1999.

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Mechanisms by which Calcium Ions Regulate the Steroidogenic Actions of Luteinizing Hormone in Isolated Ovarian Cells in Vitro*

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Mechanisms by which endothelin-1 stimulates increased cytosolic free calcium ion concentrations in single rat Sertoli cells

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Mechanisms of conjoint failure of the somatotropic and gonadal axes in ageing men.

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Mechanisms of hypoandrogenemia in healthy aging men.

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Mechanisms of hypothalamic-pituitary-gonadal disruption in polycystic ovarian syndrome

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Mechanisms of impaired fasting glucose and glucose intolerance induced by an approximate 50% pancreatectomy

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Mechanisms of insulin-like growth factor I augmentation of follicle-stimulating hormone-induced porcine steroidogenic acute regulatory protein gene promoter activity in granulosa cells

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Mechanisms of regulation of ovarian sterol metabolism by insulin-like growth factor type II: in vitro studies with swine granulosa cells

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Mechanisms of sulfonylurea's stimulation of insulin secretion in vivo: selective amplification of insulin secretory burst mass

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Mechanisms subserving calcium's modulation of luteinizing hormone action in isolated swine granulosa cells

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Mechanisms subserving hormone action in the ovary: role of calcium ions as assessed by steady state calcium exchange in cultured swine granulosa cells

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Mechanisms subserving the bipotential actions of estrogen on ovarian cells: studies with a selective anti-estrogen, LY156758, and the sparingly metabolizable estrogen agonist, moxestrol

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Mechanisms subserving the physiological nocturnal relative hypoprolactinemia of healthy older men: dual decline in prolactin secretory burst mass and basal release with preservation of pulse duration, frequency, and interpulse interval--a General Cl

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Mechanisms that subserve estradiol's induction of increased prolactin concentrations: evidence of amplitude modulation of spontaneous prolactin secretory bursts

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Mechanisms underlying endothelin's inhibition of FSH-stimulated progesterone production by ovarian granulosa cells

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Mechanisms underlying the steroidogenic synergy of insulin and luteinizing hormone in porcine granulosa cells: joint amplification of pivotal sterol-regulatory genes encoding the low-density lipoprotein (LDL) receptor, steroidogenic acute regulatory

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Metabolic acidosis inhibits growth hormone secretion in rats: mechanism of growth retardation

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Metabolic clearance of human follicle-stimulating hormone assessed by radioimmunoassay, immunoradiometric assay, and in vitro Sertoli cell bioassay

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Mode of pulsatile follicle-stimulating hormone secretion in gonadal hormone-sufficient and -deficient women--a clinical research center study

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Mode of secretion of bioactive luteinizing hormone in man.

scientific article published in November 1983

Model-Based Evaluation of Growth Hormone Secretion

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Model-independent quantification of measurement error: empirical estimation of discrete variance function profiles based on standard curves

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Model-projected mechanistic bases for sex differences in growth hormone regulation in humans

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Modeling the Nonlinear Time Dynamics of Multidimensional Hormonal Systems

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Modulation of immunoradiometric and bioactive follicle stimulating hormone secretion and clearance in young and elderly men during treatment with tamoxifen or flutamide

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Motivations and methods for analyzing pulsatile hormone secretion

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Multipathway modulation of exercise and glucose stress effects upon GH secretion in healthy men.

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Multiplication Stimulating Activity Regulates Ornithine Decarboxylase in Isolated Porcine Granutlosa Cells in Vitro

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Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.

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Nature of alpha subunit secretion in men: circadian rhythms, pulsatile release and secretory profiles

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Nature of altered growth hormone secretion in hyperthyroidism

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Nature of altered pulsatile hormone release and neuroendocrine network signalling in human ageing: clinical studies of the somatotropic, gonadotropic, corticotropic and insulin axes.

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Nature of endothelin binding in the porcine ovary

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Nature of gonadotropin-releasing hormone self-priming of luteinizing hormone secretion during the normal menstrual cycle

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Neuroendocrine Alterations in the Somatotropic Axis in Chronic Renal Failure

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Neuroendocrine adaptations in renal disease

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Neuroendocrine control of GH release during acute aerobic exercise

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Neuroendocrine control of pulsatile growth hormone release in the human: relationship with gender

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Neuroendocrine facets of human puberty

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Neuroendocrine mechanisms by which selective Leydig cell castration unleashes increased pulsatile LH release

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Neuroendocrine mechanisms mediating awakening of the human gonadotropic axis in puberty

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Neuroendocrine physiology of the normal male gonadal axis

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Neurokinin 3 Receptor Antagonism Reveals Roles for Neurokinin B in the Regulation of Gonadotropin Secretion and Hot Flashes in Postmenopausal Women

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Neurokinin 3 receptor antagonism as a novel treatment for menopausal hot flushes: a phase 2, randomised, double-blind, placebo-controlled trial

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Neurokinin 3 receptor antagonism decreases gonadotropin and testosterone secretion in healthy men.

scientific article published on 12 August 2017

Neurokinin B Receptor Antagonism in Women With Polycystic Ovary Syndrome: A Randomized, Placebo-Controlled Trial

scientific article published on 26 July 2016

Neurokinin B regulates gonadotropin secretion, ovarian follicle growth and the timing of ovulation in healthy women

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Neurophysiological regulation and target-tissue impact of the pulsatile mode of growth hormone secretion in the human

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New modalities for understanding dynamic regulation of the somatotropic (GH) axis: explication of gender differences in GH neuroregulation in the human

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Noninvasive Analytical Estimation of Endogenous GnRH Drive: Analysis Using Graded Competitive GnRH-Receptor Antagonism and a Calibrating Pulse of Exogenous GnRH

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Noninvasive in vivo investigative probes of adaptive mechanisms of neuroendocrine regulation: the paradigm of the hypothalamo-pituitary-gonadal axis in the aging male

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Normal control of growth hormone secretion

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Novel modalities for appraising individual and coordinate pulsatile hormone secretion: the paradigm of luteinizing hormone and testosterone release in the aging male

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Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp

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Objective assessment of concordance of secretory events in two endocrine time series

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Octreotide represses secretory-burst mass and nonpulsatile secretion but does not restore event frequency or orderly GH secretion in acromegaly

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Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men.

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Older men manifest multifold synchrony disruption of reproductive neurohormone outflow

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Operating behavior of dual or multiple endocrine pulse generators

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Operating characteristics of the hypothalamo-pituitary-gonadal axis in men: circadian, ultradian, and pulsatile release of prolactin and its temporal coupling with luteinizing hormone

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Operating characteristics of the male hypothalamo-pituitary-gonadal axis: pulsatile release of testosterone and follicle-stimulating hormone and their temporal coupling with luteinizing hormone

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Optimizing Blood Sampling Protocols in Patients With Acromegaly for the Estimation of Growth Hormone Secretion.

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Oscillations in joint synchrony of reproductive hormones in healthy men

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Ovarian Actions of Tumor Necrosis Factor-α (TNFα): Pleiotropic Effects of TNFα on Differentiated Functions of Untransformed Swine Granulosa Cells*

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Overnight ACTH-cortisol dose responsiveness: comparison with 24-h data, metyrapone administration and insulin-tolerance test in healthy adults

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PTH pulsatility but not calcium sensitivity is restored after total parathyroidectomy with heterotopic autotransplantation

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Paradoxical effect of 3-isobutyl-1-methylxanthine on cytochrome P450 cholesterol side-chain cleavage mRNA accumulation in porcine granulosa cells

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Pathophysiologic features of episodic gonadotropin secretion in man.

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Pathophysiological features of episodic gonadotropin secretion in man.

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Pathophysiological features of the pulsatile secretion of biologically active luteinizing hormone in man.

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Pathophysiological relationships between the biological and immunological activities of luteinizing hormone

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Pathophysiology of Pulsatile and Copulsatile Release of Thyroid-Stimulating Hormone, Luteinizing Hormone, Follicle-Stimulating Hormone, andα-Subunit*

scientific article published on August 1, 1990

Pathophysiology of hyperinsulinemia following pancreas transplantation: altered pulsatile versus Basal insulin secretion and the role of specific transplant anatomy in dogs

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Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human

scientific article published in December 1998

Patients with Cushing’s Disease Secrete Adrenocorticotropin and Cortisol Jointly More Asynchronously than Healthy Subjects

scientific article published on February 1, 1998

Patterns of GH output and their synchrony with short-term height increments influence stature and growth performance in normal children

scientific article published in December 2001

Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women

scientific article published on 8 August 2007

Persistence of concordant luteinizing hormone (LH), testosterone, and alpha-subunit pulses after LH-releasing hormone antagonist administration in normal men.

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Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults

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Physiologic attributes of the luteinizing hormone pulse signal in the human. Cross-validation studies in men.

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Physiological and pharmacological regulation of 20-kDa growth hormone

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Physiological attributes of endogenous bioactive luteinizing hormone secretory bursts in man.

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Physiological control of pituitary hormone secretory-burst mass, frequency, and waveform: a statistical formulation and analysis

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Physiological profiles of episodic progesterone release during the midluteal phase of the human menstrual cycle: analysis of circadian and ultradian rhythms, discrete pulse properties, and correlations with simultaneous luteinizing hormone release

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Physiological regulation of the human growth hormone (GH)-insulin-like growth factor type I (IGF-I) axis: predominant impact of age, obesity, gonadal function, and sleep.

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Physiological role of somatostatin on growth hormone regulation in humans

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Pioglitazone treatment increases spontaneous growth hormone (GH) secretion and stimulated GH levels in polycystic ovary syndrome

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Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women

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Pituitary-gonadal function in adolescent males born appropriate or small for gestational age with or without intrauterine growth restriction

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Pituitary-hormone secretion by thyrotropinomas

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Poorly controlled type I diabetes mellitus in young men selectively suppresses luteinizing hormone secretory burst mass

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Postprandial suppression of glucagon secretion depends on intact pulsatile insulin secretion: further evidence for the intraislet insulin hypothesis

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Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp

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Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism

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Preservation of androgen secretion during estrogen suppression with aminoglutethimide in the treatment of metastatic breast carcinoma

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Preservation of pulsatile luteinizing hormone release during postpartum lactational amenorrhea

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Primary gonadal failure in men selectively amplifies the mass of follicle stimulating hormone (FSH) secreted per burst and increases the disorderliness of FSH release patterns: reversibility with testosterone replacement

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Process irregularity of cortisol and adrenocorticotropin secretion in men with major depressive disorder

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Profound amplification of secretory-burst mass and anomalous regularity of ACTH secretory process in patients with Nelson's syndrome compared with Cushing's disease

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Progesterone Secretion by Highly Differentiated Human Granulosa Cells Isolated from Preovulatory Graafian Follicles Induced by Exogenous Gonadotropins and Human Chorionic Gonadotropin

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Proinflammatory Cytokine Infusion Attenuates LH's Feedforward on Testosterone Secretion: Modulation by Age

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Prolactin secretion in healthy adults is determined by gender, age and body mass index

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Properties of low density lipoprotein binding by cultured swine granulosa cells

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Prostaglandin F2 alpha initiates polyphosphatidylinositol hydrolysis and membrane translocation of protein kinase C in swine ovarian cells

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Pubertal alterations in growth and body composition: IX. Altered spontaneous secretion and metabolic clearance of growth hormone in overweight youth

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Pulsatile Cortisol Feedback on ACTH Secretion Is Mediated by the Glucocorticoid Receptor and Modulated by Gender

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Pulsatile cosecretion of estradiol and progesterone by the midluteal phase corpus luteum: temporal link to luteinizing hormone pulses

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Pulsatile growth hormone release in normal women during the menstrual cycle

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Pulsatile insulin secretion by human pancreatic islets

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Pulsatile insulin secretion dictates systemic insulin delivery by regulating hepatic insulin extraction in humans

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Pulsatile insulin secretion in elderly patients with diabetes

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Pulsatile insulin secretion: detection, regulation, and role in diabetes

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Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men.

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Pulsatile intravenous infusion of recombinant human luteinizing hormone under acute gonadotropin-releasing hormone receptor blockade reconstitutes testosterone secretion in young men.

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Pulsatile iv infusion of recombinant human LH in leuprolide-suppressed men unmasks impoverished Leydig-cell secretory responsiveness to midphysiological LH drive in the aging male

scientific article published in November 2001

Pulsatile release of bioactive luteinizing hormone in prepubertal girls: discordance with immunoreactive luteinizing hormone pulses

scientific article published on April 1987

Pulsatile secretion of gonadotropins and prolactin in male marathon runners. Relation to the endogenous opiate system

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Pulsatile, nyctohemeral and entropic characteristics of GH secretion in adult GH-deficient patients: selectively decreased pulsatile release and increased secretory disorderliness with preservation of diurnal timing and gender distinctions

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Pulsatility of Hypothalamo-Pituitary Hormones: A Challenge in Quantification

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Purification of three forms of chromatographically distinct protein kinase C from the swine ovary

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Putative GH pulse renewal: periventricular somatostatinergic control of an arcuate-nuclear somatostatin and GH-releasing hormone oscillator

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Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells

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Putative somatostatin suppression potentiates adrenocorticotropin secretion driven by ghrelin and human corticotropin-releasing hormone

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Quantifying nonlinear interactions within the hypothalamo-pituitary-adrenal axis in the conscious horse

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Reanalysis of the rat proestrous LH surge by deconvolution analysis

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Recent insights into neuroendocrine mechanisms of aging of the human male hypothalamic-pituitary-gonadal axis

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Recent neuroendocrine facets of male reproductive aging

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Reconstruction of in vivo time-evolving neuroendocrine dose-response properties unveils admixed deterministic and stochastic elements

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Recruitment of individually (all-or-none) responding cells, rather than amplitude enhancement, is the single-cell mechanism subserving the dose-responsive activation of intracellular calcium second messenger signaling by the human luteinizing-hormon

scientific article published on October 1, 1997

Reduced nocturnal ACTH-driven cortisol secretion during critical illness

scientific article published on 25 February 2014

Regulated recovery of pulsatile growth hormone secretion from negative feedback: a preclinical investigation

scientific article published on July 27, 2011

Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells

scientific article published on 04 December 2007

Regulation of Ornithine Decarboxylase in Isolated Granulosa Cells in Vitro by Constituents of Follicular Fluid

scientific article published on November 1, 1979

Regulation of Pulsatile and Entropic ACTH Secretion Under Fixed Exogenous Secretagogue Clamps

scientific article published on 28 March 2017

Regulation of basal, pulsatile, and entropic (patterned) modes of GH secretion in a putatively low-somatostatin milieu in women

scientific article published on 02 June 2009

Regulation of complex pulsatile and rhythmic neuroendocrine systems: the male gonadal axis as a prototype

scientific article published on January 2010

Regulation of porcine granulosa cell 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin and insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist

scientific article published on November 1, 1995

Regulation of porcine granulosa cell steroidogenic acute regulatory protein (StAR) by insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist

scientific article

Relationship between age, percentage body fat, fitness, and 24-hour growth hormone release in healthy young adults: effects of gender

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Relationship between beta-cell mass and fasting blood glucose concentration in humans

scientific article published in March 2006

Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women

scientific article published on 26 May 2009

Reliability of estimates of pulsatile characteristics of luteinizing hormone and growth hormone release in women

scientific article

Repaglinide acutely amplifies pulsatile insulin secretion by augmentation of burst mass with no effect on burst frequency

scientific article published in May 2000

Repaglinide treatment amplifies first-phase insulin secretion and high-frequency pulsatile insulin release in Type 2 diabetes

scientific article published in October 2005

Repeated bouts of exercise alter the blood lactate-RPE relation

scientific article published on July 1, 1998

Requirement for proximal putative Sp1 and AP-2 cis-deoxyribonucleic acid elements in mediating basal and luteinizing hormone- and insulin-dependent in vitro transcriptional activation of the CYP17 gene in porcine theca cells

scientific article published on 4 March 2004

Responsiveness of gonadotropin secretion to infusion of an opiate-receptor antagonist in hypogonadotropic individuals

scientific article published on October 1982

Retention of estradiol negative feedback relationship to LH predicts ovulation in response to caloric restriction and weight loss in obese patients with polycystic ovary syndrome

scientific article published on 16 December 2003

Rhythmic and nonrhythmic modes of anterior pituitary gland secretion

scientific article published on October 1, 1992

Robustness of the male lactotropic axis to the hyperprolactinemic stimulus of primary thyroidal failure

scientific article published on March 1, 1992

Saltation and stasis: a model of human growth

scientific article published on October 30, 1992

Secretagogue type, sex-steroid milieu, and abdominal visceral adiposity individually determine secretagogue-stimulated cortisol secretion

scientific article

Secretagogues govern GH secretory-burst waveform and mass in healthy eugonadal and short-term hypogonadal men.

scientific article

Secretory process regularity monitors neuroendocrine feedback and feedforward signaling strength in humans

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Sensitivity and specificity of pulse detection using a new deconvolution method

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Serum GH response to pharmacological stimuli and physical exercise in two siblings with two new inactivating mutations in the GH-releasing hormone receptor gene

scientific article published in November 2002

Sex Steroids, GHRH, Somatostatin, IGF-I, and IGFBP-1 Modulate Ghrelin's Dose-Dependent Drive of Pulsatile GH Secretion in Healthy Older Men

scientific article published on September 18, 2012

Sex defines the age dependence of endogenous ACTH-cortisol dose responsiveness

scientific article

Sex differences in circulating human leptin pulse amplitude: clinical implications

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Sex steroids modulate prolactin action in spontaneously luteinizing porcine granulosa cells in vitro

scientific article published on April 1981

Sex-Steroid Modulation of Growth Hormone (GH) Secretory Control: Three-Peptide Ensemble Regulation Under Dual Feedback Restraint by GH and IGF-I

scientific article published on October 1, 2003

Sex-steroid control of the aging somatotropic axis

scientific article published in December 2005

Short-Term Modulation of the Androgen Milieu Alters Pulsatile, But Not Exercise- or Growth Hormone (GH)-Releasing Hormone-Stimulated GH Secretion in Healthy Men: Impact of Gonadal Steroid and GH Secretory Changes on Metabolic Outcomes1

scientific article published on November 1, 1997

Short-term aromatase-enzyme blockade unmasks impaired feedback adaptations in luteinizing hormone and testosterone secretion in older men.

scientific article

Short-term estradiol replacement in postmenopausal women selectively mutes somatostatin's dose-dependent inhibition of fasting growth hormone secretion

scientific article published in July 2001

Short-term estradiol supplementation potentiates low-dose ghrelin action in the presence of GHRH or somatostatin in older women

scientific article published on 20 December 2013

Short-term fasting selectively suppresses leptin pulse mass and 24-hour rhythmic leptin release in healthy midluteal phase women without disturbing leptin pulse frequency or its entropy control (pattern orderliness).

scientific article

Short-term fasting suppresses leptin and (conversely) activates disorderly growth hormone secretion in midluteal phase women--a clinical research center study

scientific article published in March 1999

Short-term testosterone supplementation does not activate GH and IGF-I production in postmenopausal women

scientific article published in July 2005

Short-term testosterone supplementation relieves growth hormone autonegative feedback in men.

scientific article published in March 2004

Single and combined effects of growth hormone and testosterone administration on measures of body composition, physical performance, mood, sexual function, bone turnover, and muscle gene expression in healthy older men.

scientific article

Sites of inhibition of steroidogenesis by activation of protein kinase-C in swine ovarian (granulosa) cells

scientific article

Slow baseline growth and a good response to growth hormone (GH) therapy are related to elevated spontaneous GH pulse frequency in girls with Turner's syndrome

scientific article

Somatotropic and gonadotropic axes linkages in infancy, childhood, and the puberty-adult transition

scientific article

Somatotropin pulse frequency and basal concentrations are increased in acromegaly and are reduced by successful therapy

scientific article

Specific, time-dependent actions of low-dose ethinyl estradiol administration on the episodic release of growth hormone, follicle-stimulating hormone, and luteinizing hormone in prepubertal girls with Turner's syndrome

scientific article published in November 1989

Spectrum of the pulsatile characteristics of LH release in normal men.

scientific article published in March 1986

Statistically accurate estimation of hormone concentrations and associated uncertainties: methodology, validation, and applications

scientific article published on January 1, 1998

Steroidal regulation of biologically active luteinizing hormone secretion in men and women

scientific article

Stimulation of insulin secretion by a rapid intravenous calcium infusion in patients with beta-cell neoplasms of the pancreas

scientific article published in January 1986

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects

scientific article

Subcutaneous infusion of kisspeptin-54 stimulates gonadotrophin release in women and the response correlates with basal oestradiol levels

scientific article

Suppression and recovery of LH secretion by a potent and selective GnRH-receptor antagonist peptide in healthy early follicular-phase women are mediated via selective control of LH secretory burst mass

scientific article published in October 2003

Suppressive actions of a gonadotropin-releasing hormone antagonist on luteinizing hormone, follicle-stimulating hormone, and prolactin release in estrogen-deficient postmenopausal women

scientific article

Surgical versus medical management of multiple endocrine neoplasia (MEN) type I.

scientific article

Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3), and IGFBP-5 concentrations during 30-day continuous subcutaneous infusion of GH-releasing peptide-2 in older me

scientific article published in May 2004

Synchronous fluctuations of blood insulin and lactate concentrations in humans.

scientific article

Synthetic somatostatin analog (octreotide) suppresses daytime growth hormone secretion equivalently in young and older men: preserved pituitary responsiveness to somatostatin's inhibition in aging

scientific article published in December 1999

Tamoxifen Hormonal Effects

scientific article published on March 1, 1979

Temporal architecture of in vivo endocrine glandular signaling: Obtaining a secretory blueprint by deconvolution analysis

scientific article published on May 1, 1991

Temporal coupling among luteinizing hormone, follicle stimulating hormone, beta-endorphin and cortisol pulse episodes in vivo

scientific article published on March 1, 1992

Temporal pattern of renin and aldosterone secretion in men: effects of sodium balance

scientific article published on May 1, 1992

Temporal structure of in vivo growth hormone secretory events in humans

scientific article

Testing pulse detection algorithms with simulations of episodically pulsatile substrate, metabolite, or hormone release

scientific article

Testosterone Deficiency in Young Men: Marked Alterations in Whole Body Protein Kinetics, Strength, and Adiposity1

scientific article published on June 1, 1998

Testosterone and estradiol regulate free insulin-like growth factor I (IGF-I), IGF binding protein 1 (IGFBP-1), and dimeric IGF-I/IGFBP-1 concentrations

scientific article

Testosterone and oxandrolone, a nonaromatizable androgen, specifically amplify the mass and rate of growth hormone (GH) secreted per burst without altering GH secretory burst duration or frequency or the GH half-life

scientific article published on October 1990

Testosterone blunts feedback inhibition of growth hormone secretion by experimentally elevated insulin-like growth factor-I concentrations

scientific article published on 7 December 2004

Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy

scientific article published in October 2005

Testosterone supplementation in older men restrains insulin-like growth factor's dose-dependent feedback inhibition of pulsatile growth hormone secretion

scientific article

Testosterone's short-term positive effect on luteinizing-hormone secretory-burst mass and its negative effect on secretory-burst frequency are attenuated in middle-aged men.

scientific article

The Role of Estradiol as a Biological Amplifier of the Actions of Follicle-Stimulating Hormone: In Vitro Studies in Swine Granulosa Cells*

scientific article published on July 1, 1982

The aging male hypothalamic-pituitary-gonadal axis: pulsatility and feedback

scientific article

The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone

scientific article published in May 2002

The effect of caloric restriction interventions on growth hormone secretion in nonobese men and women

scientific article

The effect of long-term opiate antagonist administration to pubertal boys

scientific article published on November 1987

The effects of time following acute growth hormone administration on metabolic and power output measures during acute exercise

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The hypothalamic pulse generator: the reproductive core

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The insulin secretagogues glibenclamide and repaglinide do not influence growth hormone secretion in humans but stimulate glucagon secretion during profound insulin deficiency

scientific article

The nature of the gonadotropin-releasing hormone stimulus-luteinizing hormone secretory response of human gonadotrophs in vivo

scientific article

The orderliness of the growth hormone (GH) release process and the mean mass of GH secreted per burst are highly conserved in individual men on successive days

scientific article

The relationship between 24-hour growth hormone secretion and insulin-like growth factor I in patients with successfully treated acromegaly: impact of surgery or radiotherapy

scientific article published in January 2001

The role of cholesterol esterification in ovarian steroidogenesis: studies in cultured swine granulosa cells using a novel inhibitor of acyl coenzyme A: cholesterol acyltransferase

scientific article

The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men

scientific article

Thigh intermuscular fat is inversely associated with spontaneous GH release in post-menopausal women with abdominal obesity

scientific article published in August 2006

Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages

scientific article

Three-peptide control of pulsatile and entropic feedback-sensitive modes of growth hormone secretion: modulation by estrogen and aromatizable androgen.

scientific article

Thyrotropin secretion by thyrotropinomas is characterized by increased pulse frequency, delayed diurnal rhythm, enhanced basal secretion, spikiness, and disorderliness

scientific article published on 5 August 2008

Thyrotropin secretion in mild and severe primary hypothyroidism is distinguished by amplified burst mass and Basal secretion with increased spikiness and approximate entropy

scientific article

Thyrotropin secretion patterns in health and disease

scientific article published on 10 April 2013

Thyrotropin secretion profiles are not different in men and women

scientific article published on 22 September 2009

Time mode of growth hormone (GH) entry into the bloodstream and steady-state plasma GH concentrations, rather than sex, estradiol, or menstrual cycle stage, primarily determine the GH elimination rate in healthy young women and men.

scientific article

Tripartite Control of Dynamic ACTH-Cortisol Dose Responsiveness by Age, Body Mass Index, and Gender in 111 Healthy Adults

scientific article published on July 13, 2011

Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro

scientific article

Twenty-Four Hour Cortisol Release Profiles in Patients With Alzheimer's and Parkinson's Disease Compared to Normal Controls: Ultradian Secretory Pulsatility and Diurnal Variation

scientific article published on May 1, 1997

Twenty-four hour continuous ghrelin infusion augments physiologically pulsatile, nycthemeral, and entropic (feedback-regulated) modes of growth hormone secretion

scientific article published on July 2008

Twenty-four-hour rhythms in plasma concentrations of adenohypophyseal hormones are generated by distinct amplitude and/or frequency modulation of underlying pituitary secretory bursts

scientific article

Unequal autonegative feedback by GH models the sexual dimorphism in GH secretory dynamics

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Unequal impact of short-term testosterone repletion on the somatotropic axis of young and older men.

scientific article published on February 2002

Up-regulation of basal transcriptional activity of the cytochrome P450 cholesterol side-chain cleavage (CYP11A) gene by isoform-specific calcium-calmodulin-dependent protein kinase in primary cultures of ovarian granulosa cells

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Utility of ultrasensitive growth hormone assays in assessing aging-related hyposomatotropism

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Validation of deconvolution analysis of LH secretion and half-life

scientific article published in July 1994

Validation of growth-hormone-releasing peptide 2 for the diagnosis of adult growth hormone deficiency.

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