List of works by Nora Klöting

40 EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004 ⬇️

article

A Human REPIN1 Gene Variant: Genetic Risk Factor for the Development of Nonalcoholic Fatty Liver Disease

scientific article published on 01 January 2020

A novel thermoregulatory role for PDE10A in mouse and human adipocytes

scientific article published on 31 May 2016

ADCY5 gene expression in adipose tissue is related to obesity in men and mice

scientific article

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype

scientific article

Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high fat diet-induced obesity by counteracting adipose tissue inflammation in vivo

scientific article published on 20 September 2017

Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization

scientific article published on 10 June 2010

Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation

scientific article published on 23 September 2020

Activated Ask1-MKK4-p38MAPK/JNK Stress Signaling Pathway in Human Omental Fat Tissue May Link Macrophage Infiltration to Whole-Body Insulin Sensitivity.

scientific article

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity

scientific article

Adipocyte dysfunction, inflammation and metabolic syndrome

scientific article

Adipocyte size threshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass

scientific article published on 29 April 2014

Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats

scientific article published on 14 June 2018

Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro

scientific article published on 15 October 2013

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity

scientific article published on 05 June 2009

Adipose triglyceride lipase gene expression in human visceral obesity

scientific article published on 10 December 2007

Alleles on rat chromosome 4 (D4Got41-Fabp1/Tacr1) regulate subphenotypes of obesity

scientific article published in March 2005

Altered Autophagy in Human Adipose Tissues in Obesity.

scientific article

Altered autophagy in human adipose tissues in obesity

scientific article published on 03 November 2010

Aminoguanidine downregulates expression of cytokine-induced Fas and inducible nitric oxide synthase but not cytokine-enhanced surface antigens of rat islet cells

scientific article published in December 2003

Antioxidants prevent health-promoting effects of physical exercise in humans

scientific article

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

scientific article

Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth

scientific article published on 28 April 2008

Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors

scientific article published on 20 March 2017

Autophagy in adipose tissue of patients with obesity and type 2 diabetes

scientific article published on 26 March 2015

Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots

scientific article

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

scientific article

C57BL/6JRj mice are protected against diet induced obesity (DIO).

scientific article published on 8 December 2011

CD14 triggers autoimmune Type 1 diabetes in the NOD mouse ⬇️

scientific article published on November 12, 2003

COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size

scientific article published on 10 April 2014

COMP-Ang-1 Improves Glucose Uptake in db/db Mice with Type 2 Diabetes

scientific article published on 06 April 2020

COMP-angiopoietin-1 recovers molecular biomarkers of neuropathy and improves vascularisation in sciatic nerve of ob/ob mice

scientific article

Central vaspin administration acutely reduces food intake and has sustained blood glucose-lowering effects

scientific article published on 5 April 2011

Circulating adipocyte fatty acid binding protein is increased in chronic and acute renal dysfunction.

scientific article

Circulating adipocyte fatty acid-binding protein induces insulin resistance in mice in vivo

scientific article published on 10 April 2015

Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training.

scientific article

Circulating cell adhesion molecules in metabolically healthy obesity

scientific article published on 01 September 2020

Circulating progranulin but not renal progranulin expression is increased in renal dysfunction

scientific article published in November 2015

Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice

scientific article

Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice

scientific article

Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites

scientific article (publication date: 2015)

Diabetes per se and metabolic state influence gene expression in tissue-dependent manner of BB/OK rats

scientific article published on 01 May 2005

Dissociation Between Brown Adipose Tissue 18F-FDG Uptake and Thermogenesis in Uncoupling Protein 1-Deficient Mice

scientific article published on 12 January 2017

Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesity

scientific article published on 24 June 2020

Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity

scientific article

Effect of a 4 week physical training program on plasma concentrations of inflammatory markers in patients with abnormal glucose tolerance.

scientific article published in April 2006

Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression

scientific article published on 29 October 2009

Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity

Effects of exercise on ACE2

scientific article published on 17 September 2020

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression

scientific article published on 29 August 2007

Effects of isoflurane anesthesia on F-waves in the sciatic nerve of the adult rat.

scientific article published on 5 May 2014

Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity

scientific article published on 21 February 2013

Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity

scientific article published on 2 December 2011

Elevated autophagy gene expression in adipose tissue of obese humans: A potential non-cell-cycle-dependent function of E2F1.

scientific article published on 22 September 2015

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats

scientific article published on July 2007

Extended longevity and insulin signaling in adipose tissue

scientific article

Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue

scientific article

FSTL3 is increased in renal dysfunction

scientific article published on 3 March 2017

Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes

scientific article published on 20 December 2013

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits

scientific article published on 9 December 2015

Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio

scientific article published on 19 April 2013

Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes

scientific article published on 11 May 2007

Free fatty acids sensitize dendritic cells to amplify TH1/TH17-immune responses

scientific article

Functional relevance of genes implicated by obesity genome-wide association study signals for human adipocyte biology

scientific article published on 16 November 2012

Gene expression of PPARgamma and PGC-1alpha in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training

scientific article

Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training

scientific article published on 18 September 2007

Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target

article

Gene expression profiling supports the role of Repin1 in the pathophysiology of metabolic syndrome

scientific article published on 24 June 2011

Genes on rat chromosomes 3, 5, 10, and 16 are linked with facets of metabolic syndrome.

scientific article published on 19 February 2009

Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression

scientific article published on 5 July 2013

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity

scientific article

Genetic variation in the multifunctional transcription factor Yy1 and type 1 diabetes mellitus in the BB rat.

scientific article

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans.

scientific article published on 24 April 2006

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

scientific article

Glucose concentration and AMP-dependent kinase activation regulate expression of insulin receptor family members in rat islets and INS-1E beta cells

scientific article

Glucose regulates expression of the nerve growth factor (NGF) receptors TrkA and p75NTR in rat islets and INS-1E beta-cells

scientific article published on 27 April 2006

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes

scientific article published on 01 March 2020

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

scientific article published on 17 May 2016

Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism

scientific article

High metabolic in vivo stability and bioavailability of a palmitoylated ghrelin receptor ligand assessed by mass spectrometry

scientific article published on 10 December 2014

High-fat diet protects BB/OK rats from developing type 1 diabetes

scientific article published in September 2011

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction

scientific article published on 27 June 2016

Iddm1 and Iddm2 homozygous WOK.4BB rats develop lymphopenia, but no hyperglycemia like the BB/OK rats

scientific article published on 03 March 2011

Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation

scientific article

Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains

scientific article published in April 2014

Increased Ifi202b/IFI16 expression stimulates adipogenesis in mice and humans.

scientific article published on 24 February 2018

Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy

scientific article

Increased circulating chemerin in patients with advanced carotid stenosis.

scientific article

Insulin up-regulates natriuretic peptide clearance receptor expression in the subcutaneous fat depot in obese subjects: a missing link between CVD risk and obesity?

scientific article published on 14 March 2012

Insulin-Like Peptide 5 Interacts with Sex Hormones and Metabolic Parameters in a Gender and Adiposity Dependent Manner in Humans

scientific article published on 29 June 2016

Insulin-sensitive obesity

scientific article published on 22 June 2010

Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans

scientific article published on 5 February 2008

Is there an autoimmune process in bone? Gene expression studies in diabetic and nondiabetic BB rats as well as BB rat-related and -unrelated rat strains

scientific article published on 27 September 2005

Is there relatedness between maternal lines of Type 1 diabetic patients?

scientific article published on 01 March 2003

Leptin Within the Subphysiological to Physiological Range Dose Dependently Improves Male Reproductive Function in an Obesity Mouse Model

scientific article

Leptin decreases circulating inflammatory IL-6 and MCP-1 in mice

scientific article published on 29 November 2018

Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin

scientific article published on 28 October 2015

Leptin restores markers of female fertility in lipodystrophy

scientific article published on 23 July 2018

Leptin-deficient (ob/ob) mouse ovaries show fatty degeneration, enhanced apoptosis and decreased expression of steroidogenic acute regulatory enzyme

scientific article

Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity

scientific article (publication date: 2012)

Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice.

scientific article

Liver-specific Repin1 deficiency impairs transient hepatic steatosis in liver regeneration

scientific article published in Scientific Reports

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation.

scientific article published on 17 December 2013

Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11β-hydroxysteroid dehydrogenase type 1 expression and development of obesity

scientific article published on 12 June 2012

Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity

scientific article published on 20 March 2007

Metabolic effects of genetic variation in the human REPIN1 gene

scientific article published on 18 June 2018

MicroRNA expression in human omental and subcutaneous adipose tissue

scientific article

NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes progression

scientific article published on 16 November 2019

Neuropeptide Y impairs insulin-stimulated translocation of glucose transporter 4 in 3T3-L1 adipocytes through the Y1 receptor

scientific article published on 27 July 2011

Nicotinamide Nucleotide Transhydrogenase (Nnt) is Related to Obesity in Mice

scientific article published on 06 July 2020

Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity

scientific article published in March 2013

Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size

scientific article published on 27 July 2016

PACAP up-regulates the expression of apolipoprotein D in 3T3-L1 adipocytes. DRG/3T3-L1 co-cultures study ⬇️

scientific article published on November 13, 2010

PPP2R5C Couples Hepatic Glucose and Lipid Homeostasis

scientific article (publication date: October 2015)

Phenotypic and genetic analyses of subcongenic BB.SHR rat lines shorten the region on chromosome 4 bearing gene(s) for underlying facets of metabolic syndrome

scientific article

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans

scientific article published in October 2005

Prenatal notch1 receptor blockade by protein delta homolog 1 (DLK1) modulates adipocyte size in vivo

scientific article published on 26 October 2015

Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats

scientific article published on 17 August 2016

Pro-Neurotensin depends on renal function and is related to all-cause mortality in chronic kidney disease

scientific article published on 01 June 2020

Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight

scientific article published on 7 May 2015

Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation.

scientific article published on 8 July 2016

Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism

scientific article published on 24 July 2017

Repin1 deficiency in liver tissue alleviates NAFLD progression in mice

scientific article published on 22 November 2018

Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes

scientific journal article

Replication initiator 1 in adipose tissue function and human obesity

scientific article published on January 2013

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity

scientific article published in May 2010

Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue

scientific article published on 03 December 2008

Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass

scientific article published on 01 July 2007

Serum vaspin concentrations in human obesity and type 2 diabetes

scientific article published on 8 November 2007

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus

scientific article

TSH compensates thyroid-specific IGF-I receptor knockout and causes papillary thyroid hyperplasia

scientific article

Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice

scientific article published on 8 July 2015

Tamoxifen treatment causes early hepatic insulin resistance

scientific article published on 06 January 2020

Telomere length differences between subcutaneous and visceral adipose tissue in humans

scientific article published on 13 January 2015

The Effect of Wolffia globosa Mankai, a Green Aquatic Plant, on Postprandial Glycemic Response: A Randomized Crossover Controlled Trial

scientific article published on 10 May 2019

The Effects of Thyroid Hormones on Gene Expression of Acyl-Coenzyme A Thioesterases in Adipose Tissue and Liver of Mice

scientific article

The Fabp4-Cre-Model is Insufficient to Study Hoxc9 Function in Adipose Tissue

scientific article published on 29 June 2020

The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG

scientific article published on 01 October 2020

The Role of Iron and Nerve Inflammation in Diabetes Mellitus Type 2-Induced Peripheral Neuropathy

scientific article published on 10 March 2019

The SGLT2 inhibitor empagliflozin improves insulin sensitivity in db/db mice both as monotherapy and in combination with linagliptin

scientific article published on 13 November 2015

The brown fat-secreted adipokine neuregulin 4 is decreased in human and murine chronic kidney disease

scientific article published on 01 August 2019

The novel adipokine/hepatokine fetuin B in severe human and murine diabetic kidney disease

scientific article published on 14 February 2017

The polygenetically inherited metabolic syndrome of WOKW rats is associated with insulin resistance and altered gene expression in adipose tissue

scientific article

The polygenetically inherited metabolic syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue

scientific article published on 13 May 2013

The role of dietary non-heme iron load and peripheral nerve inflammation in the development of peripheral neuropathy (PN) in obese non-diabetic leptin-deficient ob/ob mice

scientific article published on 13 January 2019

The role of nerve inflammation and exogenous iron load in experimental peripheral diabetic neuropathy (PDN).

scientific article published on 6 November 2015

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice

scientific article published on 12 December 2016

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis

scientific article published on 01 February 2019

Transplantation of adipose tissue protects BB/OK rats from type 1 diabetes development.

scientific article published on 26 January 2011

Triplet repeat in the Repin1 3'-untranslated region on rat chromosome 4 correlates with facets of the metabolic syndrome

scientific article published on 01 July 2007

Two patterns of adipokine and other biomarker dynamics in a long-term weight loss intervention

scientific article published on 21 December 2011

Up-regulated autophagy: as a protective factor in adipose tissue of WOKW rats with metabolic syndrome.

scientific article

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes

scientific article

Vaspin inhibits kallikrein 7 by serpin mechanism

scientific article

Vaspin serum concentrations in patients with carotid stenosis

scientific article published on 2 September 2008

Visfatin is a positive regulator of MCP-1 in human adipocytes in vitro and in mice in vivo

scientific article published on 24 December 2009

Visfatin: gene expression in isolated adipocytes and sequence analysis in obese WOKW rats compared with lean control rats

scientific article published in July 2005

WISP1 is a novel adipokine linked to inflammation in obesity

scientific article published on 3 October 2014

microRNA-379 couples glucocorticoid hormones to dysfunctional lipid homeostasis

scientific article

p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet

scientific article published on 24 July 2018

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