List of works - Cathy Tournier

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis

scientific article

A novel mitogen-activated protein kinase docking site in the N terminus of MEK5alpha organizes the components of the extracellular signal-regulated kinase 5 signaling pathway.

scientific article published on November 2005

Alternative ERK5 regulation by phosphorylation during the cell cycle.

scientific article published on 25 July 2010

Can tumor cells proliferate without ERK5?

scientific article published on 29 January 2016

Dual role of ERK5 in the regulation of T cell receptor expression at the T cell surface

scientific article published on 24 August 2015

ERK5 is a critical mediator of inflammation-driven cancer

scientific article published on 3 February 2015

ERK5 regulation in naïve T-cell activation and survival.

scientific article

Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK

scientific article published on 2 March 2016

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.

scientific article

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

scientific article

Map2k4 Functions as a Tumor Suppressor in Lung Adenocarcinoma and Inhibits Tumor Cell Invasion by Decreasing Peroxisome Proliferator-Activated Receptor γ2 Expression ⬇️

scientific article published on September 6, 2011

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

scientific article

Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition.

scientific article published on 5 March 2018

Pathological axonal death through a MAPK cascade that triggers a local energy deficit

scientific article published on January 2015

REST and its downstream molecule Mek5 regulate survival of primordial germ cells.

scientific article published on 26 September 2012

Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants.

scientific article published in March 2012

Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death

scientific article

The 2 Faces of JNK Signaling in Cancer.

scientific article published on September 2013

The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion

scientific article published on 12 May 2021

The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs).

scientific article published on 15 August 2012

The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo.

scientific article published in November 2011

The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.

scientific article

The regulation of Bax by c-Jun N-terminal protein kinase (JNK) is a prerequisite to the mitochondrial-induced apoptotic pathway

scientific journal article

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy ⬇️

scientific article published on July 1, 2011

Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5

scientific article published on 16 August 2017

ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates

scientific article

p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.

scientific article published on 19 January 2012

List of works by Cathy Tournier

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis

A novel mitogen-activated protein kinase docking site in the N terminus of MEK5alpha organizes the components of the extracellular signal-regulated kinase 5 signaling pathway.

Alternative ERK5 regulation by phosphorylation during the cell cycle.

Can tumor cells proliferate without ERK5?

Dual role of ERK5 in the regulation of T cell receptor expression at the T cell surface

ERK5 is a critical mediator of inflammation-driven cancer

ERK5 regulation in naïve T-cell activation and survival.

Fibroblast Growth Factor 21 Mediates Glycemic Regulation by Hepatic JNK

Guidelines for the use and interpretation of assays for monitoring autophagy

Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma.

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

Map2k4 Functions as a Tumor Suppressor in Lung Adenocarcinoma and Inhibits Tumor Cell Invasion by Decreasing Peroxisome Proliferator-Activated Receptor γ2 Expression ⬇️

Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition.

Pathological axonal death through a MAPK cascade that triggers a local energy deficit

REST and its downstream molecule Mek5 regulate survival of primordial germ cells.

Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants.

Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death

The 2 Faces of JNK Signaling in Cancer.

The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion

The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs).

The loss of c-Jun N-terminal protein kinase activity prevents the amyloidogenic cleavage of amyloid precursor protein and the formation of amyloid plaques in vivo.

The mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.

The regulation of Bax by c-Jun N-terminal protein kinase (JNK) is a prerequisite to the mitochondrial-induced apoptotic pathway

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy ⬇️

Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5

ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates

p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction.