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List of works by Shannon L Macauley

A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration

scientific journal article

AAV2-mediated ocular gene therapy for infantile neuronal ceroid lipofuscinosis.

scientific article

An anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosis

scientific article

Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse

scientific article published on 10 February 2009

Changes in insulin and insulin signaling in Alzheimer's disease: cause or consequence?

scientific article published on 18 July 2016

Combination Therapies for Lysosomal Storage Diseases: A Complex Answer to a Simple Problem

scientific article published on June 2016

Glucagon-Like Peptide-1 Cleavage Product Improves Cognitive Function in a Mouse Model of Down Syndrome

scientific article published on 01 March 2019

Hyperglycemia modulates extracellular amyloid-β concentrations and neuronal activity in vivo

scientific article published on 4 May 2015

Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology.

scientific article published in November 2004

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

scientific article published on 29 July 2009

Neuropathology of the acid sphingomyelinase knockout mouse model of Niemann-Pick A disease including structure-function studies associated with cerebellar Purkinje cell degeneration.

scientific article published on 16 August 2008

Synergistic effects of central nervous system-directed gene therapy and bone marrow transplantation in the murine model of infantile neuronal ceroid lipofuscinosis

scientific article

Targeted Deletion of Hepatocyte Abca1 Increases Plasma HDL (High-Density Lipoprotein) Reverse Cholesterol Transport via the LDL (Low-Density Lipoprotein) Receptor

scientific article published on 06 June 2019

The Effects of Peripheral and Central High Insulin on Brain Insulin Signaling and Amyloid-β in Young and Old APP/PS1 Mice.

scientific article

The Interaction Between Sleep and Metabolism in Alzheimer's Disease: Cause or Consequence of Disease?

scientific article published on 20 September 2019

The effects of transforming growth factor-beta2 on dopaminergic graft survival.

scientific article

Type-2-Diabetes Alters CSF but Not Plasma Metabolomic and AD Risk Profiles in Vervet Monkeys

scientific article published on 28 August 2019

Widespread Expression of a Membrane-Tethered Version of the Soluble Lysosomal Enzyme Palmitoyl Protein Thioesterase-1.

scientific article published on 18 February 2017

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