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List of works by Mark Kester

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

scientific article

A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines

scientific article

AP-1 binding transcriptionally regulates human neutral ceramidase

scientific article

Altered sphingolipid metabolism in patients with metastatic pancreatic cancer

scientific article published on 25 July 2013

Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis

scientific article published on 23 February 2012

Bif-1 regulates Atg9 trafficking by mediating the fission of Golgi membranes during autophagy

scientific article

C(6)-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch-Injured Arteries

scientific article published in August 2008

C6-ceramide nanoliposomes target the Warburg effect in chronic lymphocytic leukemia

scientific article

Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells

scientific article published on December 2008

Calcium phosphate-based composite nanoparticles in bioimaging and therapeutic delivery applications

scientific article published on 30 September 2011

Calcium phosphosilicate nanoparticles for imaging and photodynamic therapy of cancer

scientific article published on April 2012

Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex

scientific article published on 21 May 2013

Ceramide kinase regulates TNFα-stimulated NADPH oxidase activity and eicosanoid biosynthesis in neuroblastoma cells ⬇️

scientific article published on December 30, 2011

Ceramide modulates HERG potassium channel gating by translocation into lipid rafts

scientific article

Ceramide nanoliposomes as a MLKL-dependent, necroptosis-inducing, chemotherapeutic reagent in ovarian cancer

scientific article published on 27 October 2017

Ceramide recruits and activates protein kinase C zeta (PKC zeta) within structured membrane microdomains

scientific journal article

Ceramide--antiestrogen nanoliposomal combinations--novel impact of hormonal therapy in hormone-insensitive breast cancer

scientific article

Ceramide-based therapeutics for the treatment of cancer

scientific article published on November 1, 2011

Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest

scientific article (publication date: February 2002)

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia

scientific article

Characterization of insulin signaling in rat retina in vivo and ex vivo

scientific article published on 10 June 2003

Circulating sphingolipid biomarkers in models of type 1 diabetes

scientific article

Clinical experience using a minimally invasive surgical approach for total knee arthroplasty: early results of a prospective randomized study compared to a standard approach

scientific article published in January 2007

Clinical, objective, and functional outcomes of manipulation under anesthesia to treat knee stiffness following total knee arthroplasty

scientific article published on 4 September 2013

Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer ⬇️

scientific article published on October 1, 2011

Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development

scientific article

Delivery of PAR-4 plasmid in vivo via nanoliposomes sensitizes colon tumor cells subcutaneously implanted into nude mice to 5-FU.

scientific article

Deregulated Akt3 activity promotes development of malignant melanoma

scientific article

Development and use of ceramide nanoliposomes in cancer.

scientific article published in January 2012

Diabetes alters sphingolipid metabolism in the retina: a potential mechanism of cell death in diabetic retinopathy

scientific article

Diabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death

scientific article

Diabetic retinopathy: seeing beyond glucose-induced microvascular disease.

scientific article

Dynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemia

scientific article

Dysregulation of sphingolipid metabolism in cancer ⬇️

scientific article published on January 15, 2011

Effect of IL-1beta on survival and energy metabolism of R28 and RGC-5 retinal neurons

scientific article

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer

scientific article published on 30 June 2017

Emerging technologies in arthroplasty: additive manufacturing

scientific article published on 24 April 2014

Encapsulation of organic molecules in calcium phosphate nanocomposite particles for intracellular imaging and drug delivery

scientific article published on December 2008

Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation.

scientific article

Ether-linked diglycerides inhibit vascular smooth muscle cell growth via decreased MAPK and PI3K/Akt signaling

scientific article published on 22 August 2008

Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression

scientific article published on 7 November 2011

Formation and role of exosomes in cancer

scientific article

Growth of human pancreatic cancer is inhibited by down-regulation of gastrin gene expression

scientific article published on July 2009

Inhibition of NADPH oxidase by glucosylceramide confers chemoresistance ⬇️

scientific article published on December 1, 2010

Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide

scientific article published on 17 April 2008

Innovations in knee arthroplasty: three-dimensional modeling and analytical technology (SOMA).

scientific article published on March 2014

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo

scientific article published on 13 September 2017

Liposomal delivery enhances short-chain ceramide-induced apoptosis of breast cancer cells

scientific article published on 15 September 2003

Long-term outcomes of MUA for stiffness in primary TKA.

scientific article published on 19 March 2013

Lysosomal degradation of CD44 mediates ceramide nanoliposome-induced anoikis and diminished extravasation in metastatic carcinoma cells

scientific article

Minimally invasive total knee arthroplasty.

scientific article

Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics

scientific article

Nanoliposomal minocycline for ocular drug delivery

scientific article published on 28 March 2012

Nanoliposomal short-chain ceramide inhibits agonist-dependent translocation of neurotensin receptor 1 to structured membrane microdomains in breast cancer cells

scientific article published on 12 May 2009

Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice

scientific article published on 30 January 2018

Nanoparticulate Alternatives for Drug Delivery ⬇️

scientific article published on September 28, 2010

Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains

scientific article

Novel Sphingolipid-Based Cancer Therapeutics in the Personalized Medicine Era

scientific article published on 19 June 2018

Paralemmin interacts with D3 dopamine receptors: implications for membrane localization and cAMP signaling

scientific article

Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway

scientific article

Preclinical development of a C6-ceramide NanoLiposome, a novel sphingolipid therapeutic

scientific article published on June 2015

Predicting the effect of tray malalignment on risk for bone damage and implant subsidence after total knee arthroplasty

scientific article

Propagation of Undifferentiated Human Embryonic Stem Cells with Nano-Liposomal Ceramide

scientific article published in January 2009

Rapid distribution of liposomal short-chain ceramide in vitro and in vivo

scientific article published on 19 May 2008

Regulatory role of sphingomyelin metabolites in hypoxia-induced vascular smooth muscle cell proliferation

scientific article

Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer

scientific article

Rotational constraint of posterior-stabilized total knee prostheses

scientific article published in October 2008

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models

scientific article published on July 2017

STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia

Short-chain ceramides depress integrin cell surface expression and function in colorectal cancer cells

scientific article

Single radius total knee arthroplasty: PCL sacrifice without substitution yields excellent outcomes minimum 8-year follow-up.

scientific article published on April 2010

Sphingolipids as therapeutics

scientific article

Sphingolipids: regulators of crosstalk between apoptosis and autophagy

scientific article

Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking

scientific article

State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy

scientific article published on 25 February 2009

Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model

scientific article

Synergistic combination therapy with nanoliposomal C6-ceramide and vinblastine is associated with autophagy dysfunction in hepatocarcinoma and colorectal cancer models

scientific article published on 07 May 2013

Systemic delivery of liposomal short-chain ceramide limits solid tumor growth in murine models of breast adenocarcinoma.

scientific article

Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53.

scientific article published on 24 January 2013

Targeting V600EB-Raf and Akt3 using nanoliposomal-small interfering RNA inhibits cutaneous melanocytic lesion development.

scientific article

Targeting glucosylceramide synthase synergizes with C6-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia

scientific article

Targeting of survivin by nanoliposomal ceramide induces complete remission in a rat model of NK-LGL leukemia

scientific article

The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines

scientific article

The therapeutic potential of nanoscale sphingolipid technologies

scientific article published on January 2013

The use of nanoparticulates to treat breast cancer

scientific article published on 4 September 2017

Therapeutic Effect of Blueberry Extracts for Acute Myeloid Leukemia

Therapeutic efficacy of FTY720 in a rat model of NK-cell leukemia

scientific article

Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer

scientific article published on 7 July 2017

Therapeutic strategies for diabetes and complications: a role for sphingolipids?

scientific article published on January 2010

Thermoresponsive and biodegradable linear-dendritic nanoparticles for targeted and sustained release of a pro-apoptotic drug

scientific article published on 26 October 2007

Toll-like receptors at the ocular surface

scientific article published on July 2008

Transcriptional regulation of the human neutral ceramidase gene

scientific article

Use of an alumina-on-alumina bearing system in total hip arthroplasty for osteonecrosis of the hip.

scientific article published in November 2006

Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels

scientific article

Vemurafenib (PLX4032): An Orally Available Inhibitor of Mutated BRAF for the Treatment of Metastatic Melanoma ⬇️

scientific article published on October 25, 2011

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