List of works - Irina Udalova

A critical role for IRF5 in regulating allergic airway inflammation.

scientific article published on 19 October 2016

Activation and function of interferon regulatory factor 5.

scientific article published on 26 September 2014

Advances and challenges in targeting IRF5, a key regulator of inflammation

scientific article published on 21 September 2018

Anti-TNF Therapy.

scientific article

Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-kappaB binding to the TNF promoter region

scientific article published on 01 July 2002

Beyond the enhanceosome: cluster of novel κB sites downstream of the human IFN-β gene is essential for lipopolysaccharide-induced gene activation.

scientific article published on 20 September 2010

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

scientific article published on 11 January 2022

Caspase-8 promotes c-Rel-dependent inflammatory cytokine expression and resistance against Toxoplasma gondii

scientific article published on 30 May 2019

Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.

scientific article

Detecting and modulating the NF-kB activity in human immune cells: generation of human cell lines with altered levels of NF-kappaB.

scientific article published in January 2009

Direct evidence for involvement of NF-kappaB in transcriptional activation of tumor necrosis factor by a spirochetal lipoprotein.

scientific article published on September 2000

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

scientific article published on 29 June 2020

Distinct transcription factor networks control neutrophil-driven inflammation

scientific article published on 19 July 2021

Diverse mechanisms of IRF5 action in inflammatory responses.

scientific article published on 22 March 2018

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction.

scientific article published on 7 September 2017

Engagement of the p55 TNF-R for different periods of time induces qualitatively distinct pathways of tumour necrosis factor signalling and gene expression profiles in murine T cells.

scientific article

Evolution of a Polymorphic Regulatory Element in Interferon-γ Through Transposition and Mutation

scientific article published in June 2002

Expression and immune function of tenascin-C.

scientific article published on January 2011

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits.

scientific article published on 29 July 2011

FOXO3 as a new IKK-ε-controlled check-point of regulation of IFN-β expression.

scientific article

Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients.

scientific article published in January 2006

Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region.

scientific article published on December 2000

Functional conservation of Rel binding sites in drosophilid genomes.

scientific article published on September 2007

Genetic polymorphism of the human tumor necrosis factor region in insulin-dependent diabetes mellitus. Linkage disequilibrium of TNFab microsatellite alleles with HLA haplotypes

scientific article published on 01 October 1995

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production.

scientific article

IL-17 boosts proinflammatory outcome of antiviral response in human cells

scientific article published on 30 September 2011

IRF5 controls both acute and chronic inflammation.

scientific article

IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.

scientific article published on 08 December 2016

IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation

scientific article published on 01 May 2020

IRF5 is a specific marker of inflammatory macrophages in vivo

scientific article published on 23 December 2013

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

scientific article

IRF5:RelA interaction targets inflammatory genes in macrophages

scientific article published on 21 August 2014

Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.

scientific article published on 28 April 2006

Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility.

scientific article published in June 2004

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

scientific article (publication date: 15 May 2002)

Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region

scientific article (publication date: 23 November 2001)

Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

scientific article published on 11 July 2017

Interferon regulatory factor 5 in human autoimmunity and murine models of autoimmune disease.

scientific article published on 04 July 2015

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

scientific article

KAP1/TRIM28: an inhibitor of IRF5 function in inflammatory macrophages

scientific article published on 11 August 2012

Localization of a long-range cis-regulatory element of IL13 by allelic transcript ratio mapping

scientific article

Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques

scientific article published on 30 October 2015

Macrophage activation and polarization: nomenclature and experimental guidelines

scientific article (publication date: 17 July 2014)

Macrophage heterogeneity in the context of rheumatoid arthritis.

scientific article published on 7 July 2016

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

scientific article published in 2023

Multiparametric Analysis of Myeloid Populations by Flow Cytometry

scientific article published on 01 January 2018

Neutrophil phenotypes and functions in cancer: A consensus statement

scientific article published in 2022

Nucleotide sequence of two exons of the human T-lymphocyte CD4 receptor gene

scientific article

Quantitative high-throughput analysis of transcription factor binding specificities.

scientific article published on 27 February 2004

Quantitative measurement of cytokine expression in synoviocytes derived from rheumatoid arthritis patients.

scientific article published in January 2009

Quantitative profiling of protein-DNA binding on microarrays.

scientific article published on January 2006

The alarmin IL-33 is a notch target in quiescent endothelial cells

scientific article published on 16 July 2012

The malarial fever response--pathogenesis, polymorphism and prospects for intervention.

scientific article published on July 1997

Transcriptional regulation of neutrophil differentiation and function during inflammation

scientific article published on 17 January 2020

Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation.

scientific article

Use of synthetic oligonucleotides for studying gene structure and polymorphism: human genes encoding tumor necrosis factors and their receptors

scientific article published on 01 January 1991

[A polymorphic markers for the p75 tumor necrosis factor receptor gene: use for analyzing disease linkage]

scientific article published on 01 December 1996

[Biochemical and immunochemical characteristics of a new oral, chemical cholera bivalent vaccine and results of a trial of the preparation on volunteers]

scientific article published on 01 January 1982

[Cloning and characteristics of the human genome locus containing genes of a second type of receptor (75 kDa) for tumor necrosis factor and lymphotoxin]

scientific article published on 01 January 1991

[Genetic polymorphism of the human genome locus containing the tumor necrosis factor gene: ethnic differences in the allele frequency distribution]

scientific article published on 01 August 1993

[The concentration of free amino acids in the blood of uterine cancer patients following surgery and radiotherapy]

scientific article published on 01 January 1970

[The molecular cloning and characteristics of the chromosomal copy of the human gene coding for the tumor-necrosis factor receptor]

scientific article published on 01 January 1990

[Two steps in activating human tumor necrosis factor gene transcription in macrophages. The role of proteins from the NF-kappa B/Rel family in the effect of lipopolysaccharide]

scientific article published on 01 May 1995

List of works by Irina Udalova

A critical role for IRF5 in regulating allergic airway inflammation.

Activation and function of interferon regulatory factor 5.

Advances and challenges in targeting IRF5, a key regulator of inflammation

Anti-TNF Therapy.

Association of accelerated erosive rheumatoid arthritis with a polymorphism that alters NF-kappaB binding to the TNF promoter region

Beyond the enhanceosome: cluster of novel κB sites downstream of the human IFN-β gene is essential for lipopolysaccharide-induced gene activation.

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

Caspase-8 promotes c-Rel-dependent inflammatory cytokine expression and resistance against Toxoplasma gondii

Complex NF-kappaB interactions at the distal tumor necrosis factor promoter region in human monocytes.

Detecting and modulating the NF-kB activity in human immune cells: generation of human cell lines with altered levels of NF-kappaB.

Direct evidence for involvement of NF-kappaB in transcriptional activation of tumor necrosis factor by a spirochetal lipoprotein.

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

Distinct transcription factor networks control neutrophil-driven inflammation

Diverse mechanisms of IRF5 action in inflammatory responses.

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction.

Engagement of the p55 TNF-R for different periods of time induces qualitatively distinct pathways of tumour necrosis factor signalling and gene expression profiles in murine T cells.

Evolution of a Polymorphic Regulatory Element in Interferon-γ Through Transposition and Mutation

Expression and immune function of tenascin-C.

Extensive characterization of NF-κB binding uncovers non-canonical motifs and advances the interpretation of genetic functional traits.

FOXO3 as a new IKK-ε-controlled check-point of regulation of IFN-β expression.

Factor H, a regulator of complement activity, is a major determinant of meningococcal disease susceptibility in UK Caucasian patients.

Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region.

Functional conservation of Rel binding sites in drosophilid genomes.

Genetic polymorphism of the human tumor necrosis factor region in insulin-dependent diabetes mellitus. Linkage disequilibrium of TNFab microsatellite alleles with HLA haplotypes

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production.

IL-17 boosts proinflammatory outcome of antiviral response in human cells

IRF5 controls both acute and chronic inflammation.

IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.

IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation

IRF5 is a specific marker of inflammatory macrophages in vivo

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

IRF5:RelA interaction targets inflammatory genes in macrophages

Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III.

Increased in vivo transcription of an IL-8 haplotype associated with respiratory syncytial virus disease-susceptibility.

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors

Interaction of AP-1 with a cluster of NF-kappa B binding elements in the human TNF promoter region

Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

Interferon regulatory factor 5 in human autoimmunity and murine models of autoimmune disease.

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity.

KAP1/TRIM28: an inhibitor of IRF5 function in inflammatory macrophages

Localization of a long-range cis-regulatory element of IL13 by allelic transcript ratio mapping

Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques

Macrophage activation and polarization: nomenclature and experimental guidelines

Macrophage heterogeneity in the context of rheumatoid arthritis.

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

Multiparametric Analysis of Myeloid Populations by Flow Cytometry

Neutrophil phenotypes and functions in cancer: A consensus statement

Nucleotide sequence of two exons of the human T-lymphocyte CD4 receptor gene

Quantitative high-throughput analysis of transcription factor binding specificities.

Quantitative measurement of cytokine expression in synoviocytes derived from rheumatoid arthritis patients.

Quantitative profiling of protein-DNA binding on microarrays.

The alarmin IL-33 is a notch target in quiescent endothelial cells

The malarial fever response--pathogenesis, polymorphism and prospects for intervention.

Transcriptional regulation of neutrophil differentiation and function during inflammation

Transcriptional regulation of the endogenous danger signal tenascin-C: a novel autocrine loop in inflammation.

Use of synthetic oligonucleotides for studying gene structure and polymorphism: human genes encoding tumor necrosis factors and their receptors

[A polymorphic markers for the p75 tumor necrosis factor receptor gene: use for analyzing disease linkage]

[Biochemical and immunochemical characteristics of a new oral, chemical cholera bivalent vaccine and results of a trial of the preparation on volunteers]

[Cloning and characteristics of the human genome locus containing genes of a second type of receptor (75 kDa) for tumor necrosis factor and lymphotoxin]

[Genetic polymorphism of the human genome locus containing the tumor necrosis factor gene: ethnic differences in the allele frequency distribution]

[The concentration of free amino acids in the blood of uterine cancer patients following surgery and radiotherapy]

[The molecular cloning and characteristics of the chromosomal copy of the human gene coding for the tumor-necrosis factor receptor]

[Two steps in activating human tumor necrosis factor gene transcription in macrophages. The role of proteins from the NF-kappa B/Rel family in the effect of lipopolysaccharide]