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List of works by Bjarne Bogen

"Troy-bodies": recombinant antibodies that target T cell epitopes to antigen presenting cells

scientific article

'Troy-bodies': antibodies as vector proteins for T cell epitopes

scientific article published in October 2001

103 Modulation of Human Basophilic Responses by a Fibroleukin-Allergen Fusion Protein.

scientific article published on 17 February 2012

A DNA Vaccine That Encodes an Antigen-Presenting Cell-Specific Heterodimeric Protein Protects against Cancer and Influenza

scientific article published on 25 January 2020

A DNA Vaccine That Targets Hemagglutinin to Antigen-Presenting Cells Protects Mice against H7 Influenza

scientific article published on 20 September 2017

A VH4-34+ myeloma protein with weak autoreactivity

scientific article published in May 2007

A model for cancer-suppressive inflammation

scientific article published on October 2012

A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation

scientific article

A mouse model for immunotherapy of myeloma.

scientific article published in January 2002

A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease

scientific article (publication date: 2012)

A public T cell receptor recognized by a monoclonal antibody specific for the D-J junction of the β-chain.

scientific article published on October 2013

A role for IL-34 in osteolytic disease of multiple myeloma

ARHGAP45 controls naïve T- and B-cell entry into lymph nodes and T-cell progenitor thymus seeding

scientific article published on 15 March 2021

Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response.

scientific article published on 12 September 2016

An Early Myeloma Bone Disease Model in Skeletally Mature Mice as a Platform for Biomaterial Characterization of the Extracellular Matrix

scientific article published on 27 June 2020

Antibodies engineered with IgD specificity efficiently deliver integrated T-cell epitopes for antigen presentation by B cells

scientific article published in July 1999

Antibody‐mediated delivery of antigen to chemokine receptors on antigen‐presenting cells results in enhanced CD4+ T cell responses ⬇️

scientific article published on 01 November 2003

Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination

scientific article published on 26 September 2016

Author Correction: Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site

scientific article published on 31 March 2020

Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice.

scientific article published on 24 February 2017

B cell receptor ligation induces display of V-region peptides on MHC class II molecules to T cells

scientific article published on 03 December 2019

B-cell tolerance to the B-cell receptor variable regions

scientific article published on 19 July 2013

Broad and Largely Concordant Molecular Changes Characterize Tolerogenic and Immunogenic Dendritic Cell Maturation in Thymus and Periphery.

scientific article published on August 2016

CD4+ T cells indirectly kill tumor cells via induction of cytotoxic macrophages in mouse models

scientific article published on 26 August 2019

CD4+ T cells kill Id+ B-lymphoma cells: FasLigand-Fas interaction is dominant in vitro but is redundant in vivo.

scientific article published on December 2004

CD4+ T-cell killing of multiple myeloma cells is mediated by resident bone marrow macrophages

scientific article published on 01 June 2020

CD4+ T-cell-Mediated Rejection of MHC Class II-Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

scientific article published on 11 May 2018

CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses

scientific article published on 10 January 2012

Ca2+ mobilization in physiologically stimulated single T cells gradually increases with peptide concentration (analog signaling).

scientific article published on April 1994

Cerebrospinal fluid T cell clones from patients with multiple sclerosis: recognition of idiotopes on monoclonal IgG secreted by autologous cerebrospinal fluid B cells

scientific article

Chaperone-assisted thermostability engineering of a soluble T cell receptor using phage display

scientific article

Chemokine-idiotype fusion DNA vaccines are potentiated by bivalency and xenogeneic sequences

scientific article published on 31 May 2007

Chronic Lymphocytic Leukemia Cells Are Activated and Proliferate in Response to Specific T Helper Cells ⬇️

scientific article published on August 8, 2013

Chronic lymphocytic leukemia cells express CD38 in response to Th1 cell-derived IFN-γ by a T-bet-dependent mechanism

scientific article published on 10 December 2014

Clonal deletion of thymocytes as a tumor escape mechanism ⬇️

scientific article published on October 5, 1998

Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity

scientific article

Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type.

scientific article published on 23 September 2011

Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target

scientific article published on 01 July 2003

Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model ⬇️

scientific article published on July 18, 2011

Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model

scientific article published on May 2017

DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease

scientific article published on 23 August 2016

DNA vaccine that targets hemagglutinin to MHC class II molecules rapidly induces antibody-mediated protection against influenza.

scientific article

DNA vaccines increase immunogenicity of idiotypic tumor antigen by targeting novel fusion proteins to antigen-presenting cells

scientific article published on 18 January 2006

DNA vaccines: MHC II-targeted vaccine protein produced by transfected muscle fibres induces a local inflammatory cell infiltrate in mice

scientific article

Deletion of idiotype (Id)-specific T cells in multiple myeloma

scientific article published on 01 January 2000

Delivery of antigen to CD40 induces protective immune responses against tumors

scientific article published in April 2007

DeltaPhage--a novel helper phage for high-valence pIX phagemid display

scientific article

Dendritic cell targeted Ccl3- and Xcl1-fusion DNA vaccines differ in induced immune responses and optimal delivery site

scientific article published in Scientific Reports

Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor

scientific article published on 01 December 1996

Efficient delivery of T cell epitopes to APC by use of MHC class II-specific Troybodies

scientific article published on March 2002

Efficient vaccine against pandemic influenza: combining DNA vaccination and targeted delivery to MHC class II molecules

scientific article

Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

scientific article

Endocytosis Deficient Murine Xcl1-Fusion Vaccine Enhances Protective Antibody Responses in Mice.

scientific article

Enhanced germinal center reaction by targeting vaccine antigen to major histocompatibility complex class II molecules

Eosinophils and megakaryocytes support the early growth of murine MOPC315 myeloma cells in their bone marrow niches

scientific article

Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation

scientific article

Expanding the tools for identifying mononuclear phagocyte subsets in swine: Reagents to porcine CD11c and XCR1.

scientific article published on 21 June 2016

Expanding the versatility of phage display I: efficient display of peptide-tags on protein VII of the filamentous phage

scientific article

Expanding the versatility of phage display II: improved affinity selection of folded domains on protein VII and IX of the filamentous phage

scientific article

Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level

scientific article published on 26 December 2007

Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor

scientific article published on 14 December 2016

Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice

scientific article published on 01 March 2012

Functional design of pH-responsive folate-targeted polymer-coated gold nanoparticles for drug delivery and in vivo therapy in breast cancer

scientific article published on 15 October 2019

Functional phage display of two murine alpha/beta T-cell receptors is strongly dependent on fusion format, mode and periplasmic folding assistance

scientific article

Genetic fusions with viral chemokines target delivery of nonimmunogenic antigen to trigger antitumor immunity independent of chemotaxis

scientific article published on 9 April 2004

Heterodimeric Barnase-Barstar Vaccine Molecules: Influence of One versus Two Targeting Units Specific for Antigen Presenting Cells ⬇️

scientific article published on September 18, 2012

How Do CD4(+) T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?

scientific article

Human CD14 is an efficient target for recombinant immunoglobulin vaccine constructs that deliver T cell epitopes

scientific article

Human Cysteine Cathepsins Degrade Immunoglobulin G In Vitro in a Predictable Manner

scientific article published on 29 September 2019

Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells

scientific article

Human chemokine MIP1α increases efficiency of targeted DNA fusion vaccines

scientific article published on 4 November 2010

Human receptors of innate immunity (CD14, TLR2) are promising targets for novel recombinant immunoglobulin-based vaccine candidates

scientific article published on 20 April 2007

IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration

scientific article published on December 2015

Idiotope-specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules

scholarly article by Bjarne Bogen et al published 1986 in European Journal of Immunology

Idiotype-specific CD4(+) T cells eradicate disseminated myeloma

scientific article published on 09 October 2015

Idiotype-specific Th cells support oligoclonal expansion of anti-dsDNA B cells in mice with lupus

scientific article published on 15 August 2014

Idiotype-specific immunotherapy in multiple myeloma: suggestions for future directions of research.

scientific article published on July 2006

Immunoglobulin as a vehicle for foreign antigenic peptides immunogenic to T cells ⬇️

scientific article published on November 1, 1997

Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models

scientific article published on 15 April 2004

In Silico Prediction Analysis of Idiotope-Driven T-B Cell Collaboration in Multiple Sclerosis

scientific article published on 2 October 2017

Increased generation of HIV-1 gp120-reactive CD8+ T cells by a DNA vaccine construct encoding the chemokine CCL3.

scientific article

Indirect CD4+ T-cell-mediated elimination of MHC II(NEG) tumor cells is spatially restricted and fails to prevent escape of antigen-negative cells

scientific article published on 20 June 2014

Induction of Cross-Reactive and Protective Antibody Responses After DNA Vaccination With MHCII-Targeted Stem Domain From Influenza Hemagglutinin

scientific article published on 25 March 2020

Induction of central T cell tolerance: recombinant antibodies deliver peptides for deletion of antigen-specific (CD4+)8+ thymocytes

scientific article published on 01 November 2005

Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer

scientific article

Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells

scientific article published on 25 July 2015

Laser-assisted intradermal delivery of adjuvant-free vaccines targeting XCR1+ dendritic cells induces potent antitumoral responses

scientific article published on 4 May 2015

Limitations of bystander killing in Th1/M1 immune responses against a secreted tumor antigen

scientific article published in October 2014

Lymphomas can develop from B cells chronically helped by idiotype-specific T cells

scientific article published on 7 May 2007

MHC-restricted Ig V region-driven T-B lymphocyte collaboration: B cell receptor ligation facilitates switch to IgG production

scientific article published in June 2004

Mechanical loading prevents bone destruction and exerts anti-tumor effects in the MOPC315.BM.Luc model of myeloma bone disease

scientific article published on 29 October 2020

Molecular profiling of tumor-specific TH1 cells activated in vivo.

scientific article published on May 2013

Monoclonal antibodies produced by muscle after plasmid injection and electroporation

scientific article published in March 2004

Naive idiotope-specific B and T cells collaborate efficiently in the absence of dendritic cells

scientific article published on 04 April 2014

Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza

scientific article published on 09 January 2019

Non-Invasive Imaging Provides Spatiotemporal Information on Disease Progression and Response to Therapy in a Murine Model of Multiple Myeloma ⬇️

scientific article published on December 26, 2012

Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model

scientific article

Periplasmic expression of soluble single chain T cell receptors is rescued by the chaperone FkpA.

scientific article

Phosphorylation-mediated EZH2 inactivation promotes drug resistance in multiple myeloma

scientific article

Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd

scientific article published in Scientific Reports

Polarizing T and B Cell Responses by APC-Targeted Subunit Vaccines

scientific article (publication date: 2015)

Preferential positive selection of T lymphocytes which express two different TCR alpha chains, an endogenous and a transgenic

scientific article published on 01 December 1995

Primary antitumor immune response mediated by CD4+ T cells

scientific article

Processing of an antigenic sequence from IgG constant domains for presentation by MHC class II

scientific article published on 01 November 2008

Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation

scientific article

Recombinant antibodies for delivery of antigen: a single loop between beta-strands in the constant region can accommodate long, complex and tandem T cell epitopes

scientific article published on 04 February 2008

Resting small B cells present endogenous immunoglobulin variable-region determinants to idiotope-specific CD4(+) T cells in vivo

scientific article published on 01 December 1999

SH2D2A modulates T cell mediated protection to a B cell derived tumor in transgenic mice

scientific article

Secretion of tumor-specific antigen by myeloma cells is required for cancer immunosurveillance by CD4+ T cells

scientific article

Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza.

scientific article published on 2 February 2018

Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells

scientific article published on 20 November 2015

Stabilizing mutations increase secretion of functional soluble TCR-Ig fusion proteins

scientific article

Surface expression of transglutaminase 2 by dendritic cells and its potential role for uptake and presentation of gluten peptides to T cells

scientific article published on 01 March 2007

Systemic Lupus Erythematosus: Molecular Mimicry between Anti-dsDNA CDR3 Idiotype, Microbial and Self Peptides-As Antigens for Th Cells

scientific article

Systemic autoimmune disease caused by autoreactive B cells that receive chronic help from Ig V region-specific T cells

scientific article

Systemic therapy with oncolytic myxoma virus cures established residual multiple myeloma in mice

scientific article published on 07 December 2016

T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation

scientific article

T cells from multiple sclerosis patients recognize multiple epitopes on Self-IgG

scientific article published on 01 October 2007

T cells with two Tcrbeta chains and reactivity to both MHC/idiotypic peptide and superantigen

scientific article published in June 1996

TLR3-responsive, XCR1+, CD141(BDCA-3)+/CD8α+-equivalent dendritic cells uncovered in healthy and simian immunodeficiency virus-infected rhesus macaques

scientific article published on 16 April 2014

Targeted DNA vaccines eliciting crossreactive anti-idiotypic antibody responses against human B cell malignancies in mice

scientific article

Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells ⬇️

scientific article published on October 30, 2012

Targeted idiotype‐fusion DNA vaccines for human multiple myeloma: preclinical testing ⬇️

scientific article published on March 30, 2011

Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response

scientific article published on 26 June 2020

Targeting Conventional Dendritic Cells to Fine-Tune Antibody Responses

scientific article published on 04 July 2019

Targeting Influenza Virus Hemagglutinin to Xcr1+ Dendritic Cells in the Absence of Receptor-Mediated Endocytosis Enhances Protective Antibody Responses

scientific article published on 22 February 2017

Targeting of HA to chemokine receptors induces strong and cross-reactive T cell responses after DNA vaccination in pigs

scientific article published on 10 December 2019

Targeting of nucleoprotein to chemokine receptors by DNA vaccination results in increased CD8(+)-mediated cross protection against influenza

scientific article published on 17 September 2015

The Magnitude and IgG Subclass of Antibodies Elicited by Targeted DNA Vaccines Are Influenced by Specificity for APC Surface Molecules

scientific article published on 18 January 2018

The anti-influenza M2e antibody response is promoted by XCR1 targeting in pig skin.

scientific article

The cellular mechanism by which complementary Id+ and anti-Id antibodies communicate: T cells integrated into idiotypic regulation

scientific article published on 12 January 2010

The heat shock transcription factor 1 as a potential new therapeutic target in multiple myeloma ⬇️

scientific article published on December 18, 2012

The idiotype connection: linking infection and multiple sclerosis

scientific article published on 02 December 2009

The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: implications for peptide vaccination

scientific article

The specificity of targeted vaccines for APC surface molecules influences the immune response phenotype

scientific article

Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies

scientific article published on 20 March 2003

Tracking early autoimmune disease by bioluminescent imaging of NF-kappaB activation reveals pathology in multiple organ systems

scientific article

Transient overexpression of CD4 enhances allelic exclusion of T-cell receptor (TCR) alpha chains and promotes positive selection of class II-restricted TCR-transgenic thymocytes.

scientific article

Troybodies and pepbodies

scientific article

Tumor Killing by CD4+ T Cells Is Mediated via Induction of Inducible Nitric Oxide Synthase-Dependent Macrophage Cytotoxicity

scientific article published on 23 July 2018

Tumor cells loaded with α-galactosylceramide promote therapeutic NKT-dependent anti-tumor immunity in multiple myeloma

scientific article published on 19 October 2013

Tumor-specific CD4+ T cells eradicate myeloma cells genetically deficient in MHC class II display

scientific article published on 10 September 2016

Tumors Escape CD4+ T-cell-Mediated Immunosurveillance by Impairing the Ability of Infiltrating Macrophages to Indirectly Present Tumor Antigens

scientific article published on 2 June 2015

Tumour necrosis factor receptor superfamily member 6 gene mutation detection by denaturing high-performance liquid chromatography

scientific article

Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages.

scientific article published on 09 December 2016

Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

scientific article published on 13 September 2016

Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8+ T-cell responses against influenza virus

scientific article published on 28 December 2014

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