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List of works by Lucía Nuñez

A new procedure for amyloid β oligomers preparation enables the unambiguous testing of their effects on cytosolic and mitochondrial Ca(2+) entry and cell death in primary neurons.

scientific article published in December 2015

A reciprocal shift in transient receptor potential channel 1 (TRPC1) and stromal interaction molecule 2 (STIM2) contributes to Ca2+ remodeling and cancer hallmarks in colorectal carcinoma cells

scientific article

Aging Enables Ca2+ Overload and Apoptosis Induced by Amyloid-β Oligomers in Rat Hippocampal Neurons: Neuroprotection by Non-Steroidal Anti-Inflammatory Drugs and R-Flurbiprofen in Aging Neurons.

scientific article published on 22 July 2016

Aging and amyloid β oligomers enhance TLR4 expression, LPS-induced Ca2+ responses, and neuron cell death in cultured rat hippocampal neurons.

scientific article published on 31 January 2017

Amyloid β Oligomers Increase ER-Mitochondria Ca Cross Talk in Young Hippocampal Neurons and Exacerbate Aging-Induced Intracellular Ca Remodeling

scientific article published on 08 February 2019

Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: A preliminary report

scientific article published on 21 July 2016

Anterior pituitary thyrotropes are multifunctional cells.

scientific article published on 29 June 2004

Association of 14-3-3 proteins to beta1-adrenergic receptors modulates Kv11.1 K+ channel activity in recombinant systems.

scientific article published on 16 August 2006

Bioluminescence imaging of mitochondrial Ca2+ dynamics in soma and neurites of individual adult mouse sympathetic neurons

scientific article published on 18 January 2007

Bioluminescence imaging of nuclear calcium oscillations in intact pancreatic islets of Langerhans from the mouse.

scientific article published in August 2005

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation.

scientific article

Calcium remodeling in colorectal cancer.

scientific article published on 10 January 2017

Calcium signaling and cell cycle: Progression or death.

scientific article published on 25 July 2017

Cytosolic phospholipase A2 is coupled to muscarinic receptors in the human astrocytoma cell line 1321N1: characterization of the transducing mechanism.

scientific article published on April 1997

Delphinidin Reduces Glucose Uptake in Mice Jejunal Tissue and Human Intestinal Cells Lines through FFA1/GPR40.

scientific article

Donor Polymorphisms in Genes Related to B-Cell Biology Associated With Antibody-Mediated Rejection After Heart Transplantation.

scientific article published on 3 April 2018

Effects of atorvastatin and simvastatin on atrial plateau currents.

scientific article published on 19 March 2007

Episodic gonadotropin-releasing hormone gene expression revealed by dynamic monitoring of luciferase reporter activity in single, living neurons ⬇️

scientific article published on August 4, 1998

Fluorescence and Bioluminescence Imaging of Subcellular Ca2+ in Aged Hippocampal Neurons.

scientific article published on December 2015

Functional effects of KCNE3 mutation and its role in the development of Brugada syndrome

scientific article

Glucose induces synchronous mitochondrial calcium oscillations in intact pancreatic islets

scientific article published on 11 May 2007

In vitro aging promotes endoplasmic reticulum (ER)-mitochondria Ca2+ cross talk and loss of store-operated Ca2+ entry (SOCE) in rat hippocampal neurons

scientific article

Inhibition of Polyamine Biosynthesis Reverses Ca Channel Remodeling in Colon Cancer Cells

scientific article published on 13 January 2019

Insights into genotype-phenotype correlation in hypertrophic cardiomyopathy. Findings from 18 Spanish families with a single mutation in MYBPC3

scientific article published on 01 December 2010

Interaction of angiotensin II with the angiotensin type 2 receptor inhibits the cardiac transient outward potassium current

scientific article published in April 2004

Intracellular Ca(2+) remodeling during the phenotypic journey of human coronary smooth muscle cells.

scientific article published on 08 September 2013

Irvalec inserts into the plasma membrane causing rapid loss of integrity and necrotic cell death in tumor cells

scientific article (publication date: 2011)

Is it all said for NSAIDs in Alzheimer's disease? Role of mitochondrial calcium uptake.

scientific article published on 27 December 2017

Lipid-lowering therapy with statins, a new approach to antiarrhythmic therapy.

scientific article published on 29 December 2006

Mechanisms for stimulation of rat anterior pituitary cells by arginine and other amino acids.

scientific article published in July 1997

Mechanisms for synchronous calcium oscillations in cultured rat cerebellar neurons.

scientific article published in January 1996

Mitochondria sustain store-operated currents in colon cancer cells but not in normal colonic cells: reversal by non-steroidal anti-inflammatory drugs

scientific article

Mitochondrial control of store-operated Ca2+ channels in cancer: Pharmacological implications

scientific article published on 03 August 2018

Multi-responsiveness of single anterior pituitary cells to hypothalamic-releasing hormones: a cellular basis for paradoxical secretion

scientific article

Multifunctional cells of mouse anterior pituitary reveal a striking sexual dimorphism.

scientific article published on 2 May 2003

Neurotoxic Ca2+ Signaling Induced by Amyloid-β Oligomers in Aged Hippocampal Neurons In Vitro

scientific article published on 01 January 2018

Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism.

scientific article published on 27 June 2006

Nitric oxide inhibits Kv4.3 and human cardiac transient outward potassium current (Ito1).

scientific article

Non-steroidal anti-inflammatory drugs (NSAIDs) and neuroprotection in the elderly: a view from the mitochondria

scientific article

Nonsteroidal anti-inflammatory drugs inhibit vascular smooth muscle cell proliferation by enabling the Ca2+-dependent inactivation of calcium release-activated calcium/orai channels normally prevented by mitochondria.

scientific article published on 14 March 2011

Phenotypic characterization of multi-functional somatotropes, mammotropes and gonadotropes of the mouse anterior pituitary

scientific article published on 01 December 2004

Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection.

scientific article published on 15 July 2017

Rapid changes in anterior pituitary cell phenotypes in male and female mice after acute cold stress.

scientific article published on 17 January 2008

Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells

scientific article published in March 2002

Remodeling of Calcium Entry Pathways in Cancer.

scientific article published on January 2016

Single-Cell Phenotypic Characterization of Human Pituitary GHomas and Non-Functioning Adenomas Based on Hormone Content and Calcium Responses to Hypothalamic Releasing Hormones

scientific article published on 9 June 2015

Store-operated Ca2+ entry and Ca2+ responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1-/- and heptaTRPC knockout mice

scientific article published on 17 November 2018

Study of neurotoxic intracellular calcium signalling triggered by amyloids

scientific article published on 01 January 2012

Susceptibility to excitotoxicity in aged hippocampal cultures and neuroprotection by non-steroidal anti-inflammatory drugs: role of mitochondrial calcium.

scientific article published on 26 January 2015

The Calcium-Sensing Receptor in Health and Disease.

scientific article

The role of mitochondrial potential in control of calcium signals involved in cell proliferation.

scientific article

Transcriptomic Analysis of Calcium Remodeling in Colorectal Cancer

scientific article

Two different constituents of plasma increase cytosolic calcium selectively in neurons or glia of primary rat cerebellar cultures.

scientific article published in February 1996

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