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List of works by Lisardo Bosca

2-deoxy-2-[18F]fluoro-d-mannose positron emission tomography imaging in atherosclerosis

scientific article published on 12 January 2014

A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: involvement of AKT-dependent mechanisms.

scientific article published on 31 December 2014

Absence of NO synthase type II expression in fetal liver from pregnant rats under septic shock conditions

scientific article published on 01 June 1997

Activation of autophagy in macrophages by pro-resolving lipid mediators.

scientific article

Activation of protein kinase C from B lymphocytes by lipid A

scientific article published on 01 April 1988

Age-related changes in the translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in rat liver

scientific article published on 01 November 1988

Anti-inflammatory action of type I interferons deduced from mice expressing interferon beta.

scientific article published in May 2000

Anti-inflammatory actions of acanthoic acid-related diterpenes involve activation of the PI3K p110γ/δ subunits and inhibition of NF-κB.

scientific article published on 24 July 2014

Atherogenesis takes place in cholesterol-fed rabbits when circulating concentrations of endogenous cortisol are increased and inflammation suppressed

scientific article published on 27 June 2006

Attenuation of NF-kappaB signalling in rat cardiomyocytes at birth restricts the induction of inflammatory genes

scientific article published on 01 November 2004

Bacterial lipopolysaccharide antagonizes transforming growth factor beta 1-induced apoptosis in primary cultures of hepatocytes

scientific article published on 01 May 1996

Benznidazole blocks NF-kappaB activation but not AP-1 through inhibition of IKK.

scientific article published on 3 July 2010

Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells

scientific article published on 23 August 2018

Bioactivity of nitrolinoleate: effects on adhesion molecules and CD40-CD40L system.

scientific article

Biphasic effect of fructose 2,6-bisphosphate on the liver fructose-1,6-bisphosphatase: mechanistic and physiological implications

scientific article published on 01 February 1984

CD2-CD48 interaction prevents apoptosis in murine B lymphocytes by up-regulating bcl-2 expression

scientific article published on 01 October 1994

CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform): A multicenter preclinical network for testing reproducibility in cardiovascular interventions

scientific article published on 30 December 2019

Cell Expansion-Dependent Inflammatory and Metabolic Profile of Human Bone Marrow Mesenchymal Stem Cells.

scientific article

Characterization of 6-phosphofructo-2-kinase from foetal-rat liver ⬇️

scientific article published on January 15, 1992

Characterization of Signals Leading to Clonal Expansion or to Cell Death During Lymphocyte B Cell Activation ⬇️

scientific article published on January 1, 1995

Characterization of nitric oxide dependent changes in carbohydrate hepatic metabolism during septic shock

scientific article published on 01 January 1996

Chronic Stress Induces the Expression of Inducible Nitric Oxide Synthase in Rat Brain Cortex

scientific article published on 01 February 2000

Coexistence of translocated cytochrome c and nitrated protein in neurons of the rat cerebral cortex after oxygen and glucose deprivation.

scientific article published in January 2002

Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages

scientific article published on 15 February 2019

Constitutive COX-2 activity in cardiomyocytes confers permanent cardioprotection Constitutive COX-2 expression and cardioprotection.

scientific article published on 25 November 2008

Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy.

scientific article published on 9 July 2001

Correction: Induction of nitric oxide synthase-2 proceeds with the concomitant downregulation of the endogenous caveolin levels (doi:10.1242/jcs.01002)

scientific article published on 04 June 2018

Critical role of the death receptor pathway in the antitumoral effects induced by hispanolone derivatives.

scientific article published on 6 February 2012

Cyclo-oxygenase 2 expression impairs serum-withdrawal-induced apoptosis in liver cells.

scientific article published on September 2006

Cyclooxygenase 2 in liver dysfunction and carcinogenesis: Facts and perspectives.

scientific article published on May 2017

Cyclooxygenase-2 expression in hepatocytes attenuates non-alcoholic steatohepatitis and liver fibrosis in mice.

scientific article published on 14 June 2016

Cyclooxygenase-2 is a target of microRNA-16 in human hepatoma cells

scientific article

Deficiency of NOD1 Improves the β-Adrenergic Modulation of Ca2+ Handling in a Mouse Model of Heart Failure.

scientific article published on 14 June 2018

Deletion or Inhibition of NOD1 Favors Plaque Stability and Attenuates Atherothrombosis in Advanced Atherogenesis †

scientific article published on 10 September 2020

Difference in glucose sensitivity of liver glycolysis and glycogen synthesis. Relationship between lactate production and fructose 2,6-bisphosphate concentration ⬇️

scientific article published on December 15, 1984

Differential calcium mobilization by vasopressin, angiotensin II, gastrin-releasing peptide, and adenosine triphosphate in adult and fetal hepatocytes. Relevance for the activation of calcium-dependent enzymes

scientific article published on 01 January 1993

Differential expression pattern of S-adenosylmethionine synthetase isoenzymes during rat liver development.

scientific article published in October 1996

Differential regulation of nitric oxide synthase mRNA expression by lipopolysaccharide and pro-inflammatory cytokines in fetal hepatocytes treated with cycloheximide ⬇️

scientific article published on November 1, 1997

Differential regulation of the expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and pyruvate kinase by cyclic adenosine 3',5'-monophosphate in fetal and adult hepatocytes

scientific journal article

Dispensability and dynamics of caveolin-1 during liver regeneration and in isolated hepatic cells.

scientific article

Down-regulation of neuronal nitric oxide synthase by nitric oxide after oxygen-glucose deprivation in rat forebrain slices.

scientific article

Electronegative LDL induction of apoptosis in macrophages: involvement of Nrf2.

scientific article

Epidermal growth factor inhibits cytokine-dependent nitric oxide synthase expression in hepatocytes

scientific article published on 01 July 1995

Evaluation of epigenetic modulation of cyclooxygenase-2 as a prognostic marker for hepatocellular carcinoma

scientific article

Evidence for Common Mechanisms in the Transcriptional Control of Type II Nitric Oxide Synthase in Isolated Hepatocytes

scientific article published in Journal of Biological Chemistry

Expression of Concern: Induction of nitric oxide synthase-2 proceeds with the concomitant downregulation of the endogenous caveolin levels. J. Cell Sci. doi: 10.1242/jcs.01002.

scientific article published on 30 August 2017

Expression of cyclooxygenase-2 in foetal rat hepatocytes stimulated with lipopolysaccharide and pro-inflammatory cytokines.

scientific article

Expression of cyclooxygenase-2 promotes the release of matrix metalloproteinase-2 and -9 in fetal rat hepatocytes.

scientific article published in April 2001

From apoptosis to autoimmunity: insights from the signaling pathways leading to proliferation or to programmed cell death.

scientific article published on December 1994

Fructose 2,6-bisphosphate in isolated foetal hepatocytes

scientific article published on 01 December 1987

GM-CSF Enhances Macrophage Glycolytic Activity In Vitro and Improves Detection of Inflammation In Vivo

scientific article published on 14 April 2016

GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice

scientific article published on 30 January 2018

H-Ras-specific activation of NF-kappaB protects NIH 3T3 cells against stimulus-dependent apoptosis.

scientific article

Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity, and insulin resistance.

scientific article published on 24 November 2014

Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.

scientific article published on 27 August 2010

ILK mediates LPS-induced vascular adhesion receptor expression and subsequent leucocyte trans-endothelial migration

scientific article published on 17 February 2010

Identification of a novel Pfkfb1 mRNA variant in rat fetal liver.

scientific article published on 3 January 2013

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.

scientific article published on 17 April 2014

Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration.

scientific article

Implication of Glutamate in the Expression of Inducible Nitric Oxide Synthase After Oxygen and Glucose Deprivation in Rat Forebrain Slices

scientific article published on 01 May 2000

Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain.

scientific article

Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis.

scientific article published on November 2006

Inflammation in Parkinson's Disease: Mechanisms and Therapeutic Implications

scientific article published on 14 July 2020

Inhibition of 6-phosphofructo-2-kinase activity by mercaptopurines

scientific article published on February 18, 1992

Inhibition of NOS-2 expression in macrophages through the inactivation of NF-kappaB by andalusol. ⬇️

scientific article published on October 1999

Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: involvement of phosphatidylinositol 3-kinase.

scientific article published on February 2000

Interferon-alpha/beta inhibits the apoptosis induced by lipopolysaccharide and interferon-gamma in murine peritoneal macrophages

scientific article published on 01 July 1998

Interleukin-4 and interleukin-10 modulate nuclear factor kappaB activity and nitric oxide synthase-2 expression in Theiler's virus-infected brain astrocytes.

scientific article

Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort

scientific article published on 01 January 2019

Intracellular water motion decreases in apoptotic macrophages after caspase activation.

scientific article

Involvement of mitogen-activated protein kinases in the symbiosis Bradyrhizobium-Lupinus

scientific article published on 25 July 2006

Involvement of monocytes/macrophages as key factors in the development and progression of cardiovascular diseases.

scientific article published on March 2014

Isoenzymes of carbohydrate metabolism in primary cultures of hepatocytes from thioacetamide-induced rat liver necrosis: responses to growth factors.

scientific article

Kaurane diterpenes protect against apoptosis and inhibition of phagocytosis in activated macrophages.

scientific article

LXR Signaling Regulates Macrophage Survival and Inflammation in Response to Ionizing Radiation

scientific article published on 25 March 2019

Lack of correlation between translocation and biological effects mediated by protein kinase C: an appraisal.

scientific article

Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices

scientific article published on 01 April 2000

Metabolic signatures linked to macrophage polarization: from glucose metabolism to oxidative phosphorylation.

scientific article published on 3 August 2015

Mild and Short-Term Caloric Restriction Prevents Obesity-Induced Cardiomyopathy in Young Zucker Rats without Changing in Metabolites and Fatty Acids Cardiac Profile.

scientific article published on February 2017

Mitochondrial DAMPs induce endotoxin tolerance in human monocytes: an observation in patients with myocardial infarction.

scientific article

Mitochondrial membrane-bound hexokinase of ascites tumor cells. Functional implications of lysine residues studied by modification with imidoesters

scientific article published on 01 June 1982

Modulation of voltage-dependent and inward rectifier potassium channels by 15-epi-lipoxin-A4 in activated murine macrophages: implications in innate immunity.

scientific article published on 18 November 2013

NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.

scientific article published on 15 September 2014

NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes

scientific article published on November 2016

NOD1 activation induces cardiac dysfunction and modulates cardiac fibrosis and cardiomyocyte apoptosis

scientific journal article

NOD1 receptor is up-regulated in diabetic human and murine myocardium.

scientific article

NOD1, a new player in cardiac function and calcium handling.

scientific article published on 30 March 2015

Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices.

scientific article published in February 1998

New PPARγ partial agonist improves obesity-induced metabolic alterations and atherosclerosis in LDLr(-/-) mice

scientific article published on 16 December 2015

New indole-thiazolidine attenuates atherosclerosis in LDLr(-/-) mice.

scientific article

New thiazolidinediones affect endothelial cell activation and angiogenesis.

scientific article published on 21 April 2016

Nitric oxide and cell signaling: in vivo evaluation of NO-dependent apoptosis by MRI and not NMR techniques

scientific article published on 01 January 2005

Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophage function and fate.

scientific article

Nitric oxide and resolution of inflammation.

scientific article published on January 2002

Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.

scientific article published in June 1997

Nitric oxide is released in regenerating liver after partial hepatectomy*1

scientific article published on 01 March 1995

Nuclear factor kappaB is required for the transcriptional control of type II NO synthase in regenerating liver.

scientific article published on September 1997

Oleate-induced translocation of protein kinase C to hepatic microsomal membranes

scientific article published on 01 May 1989

PGE1-induced NO reduces apoptosis by D-galactosamine through attenuation of NF-kappaB and NOS-2 expression in rat hepatocytes.

scientific article published in December 2004

PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p.

scientific article published on 3 November 2017

Peroxisome proliferator-activated receptor-gamma-independent inhibition of macrophage activation by the non-thiazolidinedione agonist L-796,449. Comparison with the effects of 15-deoxy-delta(12,14)-prostaglandin J(2).

scientific article published on 3 July 2001

Phorbol 12-myristate 13-acetate and insulin increase the concentration of fructose 2,6-bisphosphate and stimulate glycolysis in chicken embryo fibroblasts.

scientific article published on October 1985

Phorbol esters induce nitric oxide synthase and increase arginine influx in cultured peritoneal macrophages

scientific article published on 01 April 1993

Phorbol esters, bombesin and insulin elicit differential responses on the 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase system in primary cultures of foetal and adult rat hepatocytes

scientific article published on 01 July 1992

Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge

scientific article published on 13 March 2014

Platelet-activating factor: the effector of protein-rich plasma extravasation and nitric oxide synthase induction in rat immune complex peritonitis

scientific article published on February 1995

Post-translational modifications of prostaglandin-endoperoxide synthase 2 in colorectal cancer: An update

scientific article published on 01 December 2018

Potentiation of protein kinase C zeta activity by 15-deoxy-delta(12,14)-prostaglandin J(2) induces an imbalance between mitogen-activated protein kinases and NF-kappa B that promotes apoptosis in macrophages.

scientific article

Presence of a nitric oxide synthase inhibitor in the graft efflux during reperfusion in human liver transplantation

scientific article published on 01 June 1999

Presence of antibody to A- and B-transferases in minor incompatible bone marrow transplant

scientific article published on 01 December 1988

Presence of methylated arginine derivatives in orthotopic human liver transplantation: relevance for liver function.

scientific article

Progression of liver oncogenesis in the double transgenic mice c-myc/TGF α is not enhanced by cyclooxygenase-2 expression.

scientific article published on 8 April 2013

Prolonged leptin treatment increases transient outward K⁺ current via upregulation of Kv4.2 and Kv4.3 channel subunits in adult rat ventricular myocytes.

scientific article published on 18 September 2013

Prostaglandin E2 Impairs P2Y2/P2Y4 Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors

scientific article published on 22 December 2017

Prostaglandin E2 promotes migration and adhesion in hepatocellular carcinoma cells.

scientific article published on 20 January 2005

Protection against Fas-induced liver apoptosis in transgenic mice expressing cyclooxygenase 2 in hepatocytes

article

Protection against gamma-radiation injury by protein tyrosine phosphatase 1B.

scientific article published on 21 April 2018

Protective Role of Hepatocyte Cyclooxygenase-2 Expression Against Liver Ischemia-Reperfusion Injury in Mice

scientific article published on 17 February 2019

Protein kinase C V3 domain mutants with differential sensitivities to m-calpain are not resistant to phorbol-ester-induced down-regulation.

scientific article

Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection

scientific journal article

Rapid Up-regulation of IκBβ and Abrogation of NF-κB Activity in Peritoneal Macrophages Stimulated with Lipopolysaccharide

scientific article published in Journal of Biological Chemistry

Rat liver messenger ribonucleic acid and enzyme activity of 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase impairment during the late period of pregnancy

scientific article published on 01 September 1993

Regional distribution of hyperpolarization‐activated current (If) and hyperpolarization‐activated cyclic nucleotide‐gated channel mRNA expression in ventricular cells from control and hypertrophied rat hearts ⬇️

scientific article published on September 26, 2003

Regulation of 15-hydroxyprostaglandin dehydrogenase expression in hepatocellular carcinoma.

scientific article published on 15 August 2013

Regulation of MicroRNA 183 by Cyclooxygenase 2 in Liver Is DEAD-Box Helicase p68 (DDX5) Dependent: Role in Insulin Signaling.

scientific article published on 11 May 2015

Regulation of rat liver S-adenosylmethionine synthetase during septic shock: role of nitric oxide

scientific article published on 01 February 1997

Relationship between genomic DNA ploidy and parameters of liver damage during necrosis and regeneration induced by thioacetamide

scientific article published on 01 October 1993

Relevance of the MEK/ERK signaling pathway in the metabolism of activated macrophages: a metabolomic approach.

scientific article

Requirement of nitric oxide and calcium mobilization for the induction of apoptosis in adrenal vascular endothelial cells

scientific article published on 01 August 1997

Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression.

scientific article

Role of NOD1 in Heart Failure Progression via Regulation of Ca2+ Handling.

scientific article published in January 2017

Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.

scientific article published in February 2006

Selective impairment of P2Y signaling by prostaglandin E2 in macrophages: implications for Ca2+-dependent responses

scientific journal article

Selective impairment of nuclear factor-kappaB-dependent gene transcription in adult cardiomyocytes: relevance for the regulation of the inflammatory response in the heart.

scientific article

Simultaneous abrogation of NOS-2 and COX-2 activities is lethal in partially hepatectomised mice.

scientific article published in June 2004

Specific Contribution of p19ARF to Nitric Oxide-Dependent Apoptosis

scientific article published on 01 September 2006

Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights

scientific article published on 20 October 2020

Specific activation by fructose 2,6-bisphosphate and inhibition by P-enolpyruvate of ascites tumor phosphofructokinase

scientific article published on 01 May 1982

Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels

scientific article

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

scientific article published on 24 May 2010

Substrate specificity of protein kinase C inhibitors

scientific article published on 01 December 1990

Substrate-dependent inhibition of protein kinase C by specific inhibitors.

scientific article published in April 1990

Sulfonylureas activate glycogen phosphorylase and increase cytosolic free-Ca2+ levels in isolated rat hepatocytes

scientific article published on 01 May 1993

Suppression of inflammatory responses by labdane-type diterpenoids.

scientific article published on 14 December 2007

Surgical excision of bone sarcomas involving the sacroiliac joint

scientific article published on 01 October 2006

Sustained release of prostaglandin E₂ in fibroblasts expressing ectopically cyclooxygenase 2 impairs P2Y-dependent Ca²⁺-mobilization

scientific article

The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras

scientific article published on 01 July 2018

The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.

scientific article published on 4 June 2004

The effect of fructose 2,6-bisphosphate on muscle fructose-1,6-bisphosphatase activity

scientific article published on 01 April 1985

The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells

scientific article published on 9 June 2006

The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress.

scientific article published in February 2002

The nNOS inhibitor, AR-R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum

scientific article published on April 2003

The nonthiazolidinedione PPARgamma agonist L-796,449 is neuroprotective in experimental stroke.

scientific article

Thioacetamide-induced liver regeneration involves the expression of cyclooxygenase 2 and nitric oxide synthase 2 in hepatocytes.

scientific article

Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta.

scientific article published on 11 September 2003

Translocation of phosphatidate phosphohydrolase from the cytosol to microsomal membranes in thioacetamide-induced liver tumours in rats

scientific article published on 01 April 1989

Up-regulation of protein kinase C-epsilon promotes the expression of cytokine-inducible nitric oxide synthase in RAW 264.7 cells.

scientific article published on December 1996

[Atypical metastatic sites in rectal cancer]

scientific article published on 01 June 2000

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