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List of works by Tanja Hakkarainen

CD40 is expressed on ovarian cancer cells and can be utilized for targeting adenoviruses

scientific article published in February 2003

Cancer cells as targets for lentivirus-mediated gene transfer and gene therapy.

scientific article published in December 2004

Cell surface structures influence lung clearance rate of systemically infused mesenchymal stromal cells

scientific article published on February 2013

Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus

scientific article published in September 2003

Generation of a conditionally replicating adenovirus based on targeted destruction of E1A mRNA by a cell type-specific MicroRNA.

scientific article

HIV-1 TAT protein transduction domain mediates enhancement of enzyme prodrug cancer gene therapy in vitro: a study with TAT-TK-GFP triple fusion construct.

scientific article published on July 2005

Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors

scientific article published in July 2007

In vivo enhancement of herpes simplex virus thymidine kinase/ganciclovir cancer gene therapy with polyamine biosynthesis inhibition

scientific article

Induction of Interferon Pathways Mediates In Vivo Resistance to Oncolytic Adenovirus

scientific article published on July 26, 2011

Mre11 inhibition by oncolytic adenovirus associates with autophagy and underlies synergy with ionizing radiation

scientific article

Noninvasive imaging for evaluation of the systemic delivery of capsid-modified adenoviruses in an orthotopic model of advanced lung cancer

scientific article published in October 2006

Oncolytic Semliki forest virus vector as a novel candidate against unresectable osteosarcoma

scientific article published on October 2008

Oncolytic adenoviruses kill breast cancer initiating CD44+CD24-/low cells

scientific article

Production of an EGFR targeting molecule from a conditionally replicating adenovirus impairs its oncolytic potential

scientific article published in August 2003

SPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131I

scientific article

Sodium iodide symporter SPECT imaging of a patient treated with oncolytic adenovirus Ad5/3-Δ24-hNIS

scientific article published on April 2011

Systemic efficacy of oncolytic adenoviruses in imagable orthotopic models of hormone refractory metastatic breast cancer

scientific article published on July 2007

TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo.

scientific article published on October 2003

Targeted chemotherapy for head and neck cancer with a chimeric oncolytic adenovirus coding for bifunctional suicide protein FCU1.

scientific article published on 13 April 2010

Targeted radiotherapy for prostate cancer with an oncolytic adenovirus coding for human sodium iodide symporter

scientific article

The cyclo-oxygenase 2 promoter is induced in nontarget cells following adenovirus infection, but an AU-rich 3'-untranslated region destabilization element can increase specificity

scientific article

The secretory leukoprotease inhibitor (SLPI) promoter for ovarian cancer gene therapy

scientific article published on April 1, 2003

Tissue-specific promoters active in CD44+CD24-/low breast cancer cells

scientific article

Transcriptional targeting of virus-mediated gene transfer by the human hexokinase II promoter

scientific article published on November 2006

Transient proteolytic modification of mesenchymal stromal cells increases lung clearance rate and targeting to injured tissue

scientific article published on 03 June 2013

Treatment of metastatic renal cancer with capsid-modified oncolytic adenoviruses

scientific article published in October 2007

Treatment of prostate cancer with Ad5/3Delta24hCG allows non-invasive detection of the magnitude and persistence of virus replication in vivo

scientific article published in February 2007

Triple-targeted oncolytic adenoviruses featuring the cox2 promoter, E1A transcomplementation, and serotype chimerism for enhanced selectivity for ovarian cancer cells

scientific article published on 31 March 2006

Type I interferon response against viral and non-viral gene transfer in human tumor and primary cell lines

scientific article published on February 2007

Utility of cell-permeable peptides for enhancement of virus-mediated gene transfer to human tumor cells

scientific article published on May 2006

VP22 does not significantly enhance enzyme prodrug cancer gene therapy as a part of a VP22-HSVTk-GFP triple fusion construct.

scientific article

Validity and reliability of the Fatigue Severity Scale in Finnish multiple sclerosis patients

scientific article

Validity and reliability of the Finnish version of the Multiple Sclerosis Impact Scale-29.

scientific article

[Adenoviruses in cancer therapy]

scientific article published on 01 January 2005

hCAR-EGFP fusion receptor in human follicular lymphoma B cells - a model for adenoviral gene therapy for B cell malignancies.

scientific article published on June 2006